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Browsing MIT Open Access Articles by Title

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  • A 76GHz PLL for mm-wave imaging applications 
    Nguyen, Khoa M.; Kim, Helen H.; Sodini, Charles G. (Institute of Electrical and Electronics Engineers (IEEE), 2010-01)
    A 76 GHz phase-locked loop (PLL) was designed in 0.13 μm IBM BiCMOS8HP technology with the intended application of millimeter-wave imaging. The PLL has a type II second order loop filter. The voltage-controlled oscillator ...
  • A 78 dB SNDR 87 mW 20 MHz Bandwidth Continuous-Time Delta Sigma ADC With VCO-Based Integrator and Quantizer Implemented in 0.13 mu m CMOS 
    Park, Matthew; Perrott, Michael H. (Institute of Electrical and Electronics Engineers, 2009-12)
    The use of a VCO-based integrator and quantizer within a continuous-time (CT) \Delta \Sigma analog-to-digital converter (ADC) structure is explored, and a custom prototype in a 0.13 \mum CMOS with a measured performance ...
  • The AAA+ ClpX machine unfolds a keystone subunit to remodel the Mu transpososome 
    Baker, Tania; Sauer, Robert T.; Abdelhakim, Aliaa H. (National Academy of Sciences (U.S.), 2009-09)
    A hyperstable complex of the tetrameric MuA transposase with recombined DNA must be remodeled to allow subsequent DNA replication. ClpX, a AAA+ enzyme, fulfills this function by unfolding one transpososome subunit. Which ...
  • Aberrant AKT activation drives well-differentiated liposarcoma 
    Marino-Enriquez, Adrian; Zhang, Yi-Xiang; Sioletic, Stefano; Kozakewich, Elena; Grebliunaite, Ruta; Ou, Wen-bin; Sicinska, Ewa; Raut, Chandrajit P.; Demetri, George D.; Perez-Atayde, Antonio R.; Wagner, Andrew J.; Fletcher, Jonathan A.; Fletcher, Christopher D. M.; Look, A. Thomas; Snyder, Eric; Gutierrez, Alejandro (Proceedings of the National Academy of Sciences (PNAS), 2011-09)
    Well-differentiated liposarcoma (WDLPS), one of the most common human sarcomas, is poorly responsive to radiation and chemotherapy, and the lack of animal models suitable for experimental analysis has seriously impeded ...
  • Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase 
    Greenblatt, Wesley H.; Rubenstein, Eric M.; Kreft, Stefan G.; Swanson, Robert; Hochstrasser, Mark (Rockefeller University Press, The, 2012-06)
    Little is known about quality control of proteins that aberrantly or persistently engage the endoplasmic reticulum (ER)-localized translocon en route to membrane localization or the secretory pathway. Hrd1 and Doa10, the ...
  • Ab initio converse NMR approach for pseudopotentials 
    Ceresoli, Davide; Marzari, Nicola; Lopez, M. G.; Thonhauser, T. (American Physical Society, 2010-05)
    We extend the recently developed converse NMR approach [Thonhauser et al., J. Chem. Phys. 131, 101101 (2009)] such that it can be used in conjunction with norm-conserving, nonlocal pseudopotentials. This extension permits ...
  • Ab initio investigation of high multiplicity Rþ—Rþ [sigma superscript + - sigma superscript +] optical transitions in the spectra of CN and isoelectronic species 
    Kulik, Heather J.; Steeves, Adam H.; Field, Robert W. (Elsevier ScienceDirect, 2009-08)
    Based on high-level ab initio calculations, we predict the existence of a strong 4Σ+–4Σ+ [superscript 4 sigma superscript + - superscript 4 sigma superscript +] optical transition (dav=1.6 D) [(d subscript av = 1.6 D)] ...
  • Ab initio reconstruction of transcriptomes of pluripotent and lineage committed cells reveals gene structures of thousands of lincRNAs 
    Guttman, Mitchell; Garber, Manuel; Levin, Joshua Z.; Donaghey, Julie; Robinson, James; Adiconis, Xian; Fan, Lin; Koziol, Magdalena J.; Gnirke, Andreas; Nusbaum, Chad; Rinn, John L.; Lander, Eric S.; Regev, Aviv (Nature Publishing Group, 2010-07)
    RNA-Seq provides an unbiased way to study a transcriptome, including both coding and noncoding genes. To date, most RNA-Seq studies have critically depended on existing annotations, and thus focused on expression levels ...
  • Ab initio study of structural stability of small 3d late transition metal clusters: Interplay of magnetization and hybridization 
    Datta, Soumendu; Saha-Dasgupta, Tanusri; Kabir, Mohammad Mukul (American Physical Society, 2011-07)
    Using first-principles density-functional-theory–based calculations, we analyze the structural stability of small clusters of 3d late transition metals. We consider the relative stability of the two structures: layer-like ...
  • Ab initio study of the low-temperature phases of lithium imide 
    Mueller, Timothy K.; Ceder, Gerbrand (American Physical Society, 2010-11)
    We present a low-temperature structural model for lithium imide (Li[subscript 2]NH) that is consistent with experimental studies. Using the cluster expansion formalism and density-functional theory, we have identified a ...
  • Abl Kinase Inhibits the Engulfment of Apoptotic [corrected] Cells in Caenorhabditis elegans 
    Hurwitz, Michael Eliezer; Vanderzalm, Pamela J.; Bloom, Laird; Goldman, Julia; Garriga, Gian; Horvitz, H. Robert (Public Library of Science, 2009-04)
    The engulfment of apoptotic cells is required for normal metazoan development and tissue remodeling. In Caenorhabditis elegans, two parallel and partially redundant conserved pathways act in cell-corpse engulfment. One ...
  • Abortion and Selection 
    Gruber, Jonathan; Ananat, Elizabeth Oltmans; Staiger, Douglas; Levine, Phillip B. (MIT Press, 2009-01)
    Abortion legalization in the early 1970s led to dramatic changes in fertility. Some research has suggested that it altered cohort outcomes, but this literature has been limited and controversial. In this paper, we provide ...
  • Abrupt coupling between strongly dissimilar waveguides with 100% transmission 
    Kurs, Andre B.; Joannopoulos, John D.; Soljacic, Marin; Johnson, Steven G. (Optical Society of America, 2011-06)
    We present numerical experiments showing how coupled-mode theory can be systematically applied to join very dissimilar photonic crystal waveguides with 100% transmission. Our approach relies on appropriately tuning the ...
  • Absolute Continuity of Brownian Bridges Under Certain Gauge Transformations 
    Nahmod, Andrea R.; Rey-Bellet, Luc; Sheffield, Scott Roger; Staffilani, Gigliola (International Press, 2011-01)
    We prove absolute continuity of Gaussian measures associated to complex Brownian bridges under certain gauge transformations. As an application we prove that the invariant measure for the periodic derivative nonlinear ...
  • Absolute Generality Reconsidered 
    Rayo, Agustin (Oxford University Press, 2012-12)
    Years ago, when I was young and reckless, I believed that there was such a thing as an allinclusive domain.1 Now I have come to see the error of my ways. The source of my mistake was a view that might be labeled ...
  • Absolute Raman matrix elements of graphene and graphite 
    Reich, Stephanie; Panknin, Robert; Narula, Rohit (American Physical Society, 2010-07)
    Using sample substitution [Grimsditch et al., J. Raman Spectrosc. 10, 77 (1981)] we deconvolve the highly wavelength-dependent response of the spectrometer from the Raman spectra of graphene suspended on an SiO[subscript ...
  • Absorption of lower hybrid waves in the scrape off layer of a diverted tokamak 
    Wallace, Gregory Marriner; Parker, Ronald R.; Bonoli, Paul T.; Hubbard, Amanda E.; Hughes, Jerry W.; LaBombard, Brian; Meneghini, Orso-Maria Corneli; Schmidt, Andrea Elizabeth; Shiraiwa, Shunichi; Whyte, Dennis G.; Wright, John C.; Wukitch, Stephen James; Smirnov, A. P.; Wilson, J. R. (American Institute of Physics, 2010-08)
    The goal of the Lower Hybrid Current Drive (LHCD) system on the Alcator C-Mod tokamak [ Hutchinson et al., Phys. Plasmas 1, 1511 (1994) ] is to investigate current profile control under plasma conditions relevant to future ...
  • The abstract MAC layer 
    Kuhn, Fabian; Lynch, Nancy Ann; Newport, Calvin Charles (Association for Computing Machinery, 2009-09)
    A diversity of possible communication assumptions complicates the study of algorithms and lower bounds for radio networks. We address this problem by defining an Abstract MAC Layer. This service provides reliable local ...
  • An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data 
    Burge, Christopher B.; Wang, Eric T.; Ramsköld, Daniel; Sandberg, Rickard (Public Library of Science, 2009-12)
    The parts of the genome transcribed by a cell or tissue reflect the biological processes and functions it carries out. We characterized the features of mammalian tissue transcriptomes at the gene level through analysis of ...
  • Abyssal Atlantic circulation during the Last Glacial Maximum: Constraining the ratio between transport and vertical mixing 
    Ferrari, Raffaele; Lund, D. C.; Adkins, J. F. (American Geophysical Union (AGU), 2011-03)
    The ocean's role in regulating atmospheric carbon dioxide on glacial-interglacial timescales remains an unresolved issue in paleoclimatology. Reduced mixing between deep water masses may have aided oceanic storage of ...
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