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Browsing MIT Open Access Articles by Title

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  • Wang, Danhua; Turitsyn, Konstantin; Chertkov, Michael (Institute of Electrical and Electronics Engineers, 2012-12)
    We consider a linear feeder connecting multiple distributed loads and generators to the sub-station. Voltage is controlled directly at the sub-station, however, voltage down the line shifts up or down, in particular depending ...
  • Haslam, Bryan Todd; Gordhandas, Ankit; Ricciardi, Catherine; Verghese, George C.; Heldt, Thomas (2011-08)
    Medical electronic systems are generating ever larger data sets from a variety of sensors and devices. Such systems are also being packaged in wearable designs for easy and broad use. The large volume of data and the ...
  • Rajagopal, Nisha; Kellis, Manolis; Ernst, Jason; Ray, Pradipta; Wu, Jie; Zhang, Michael; Ren, Bing (Genetics Society of America, 2014-08)
    In eukaryotic cells, histone lysines are frequently acetylated. However, unlike modifications such as methylations, histone acetylation modifications are often considered redundant. As such, the functional roles of distinct ...
  • Guth, Lawrence (Springer US, 2014-12)
    We give a shorter proof of a slightly weaker version of a theorem from Guth and Katz (Ann Math 181:155–190, 2015): we prove that if L is a set of L lines in R[superscript 3] with at most L[superscript 1/2] lines in any ...
  • King, A. L.; Miller, J. M.; Cackett, E. M.; Fabian, Andrew C.; Markoff, Sera B.; Rupen, M.; Reynolds, M. T.; Nowak, Michael A.; Gultekin, K. (IOP Publishing, 2010-02)
    We report on the results of a simultaneous monitoring campaign employing eight Chandra X-ray (0.5-10 keV) and six Very Large Array/Extended Very Large Array (8.4 GHz) radio observations of NGC 4051 over seven months. ...
  • Rago, Florencia; Gascoigne, Karen E.; Cheeseman, Iain M (Elsevier, 2015-02)
    The kinetochore provides a vital connection between chromosomes and spindle microtubules [1 and 2]. Defining the molecular architecture of the core kinetochore components is critical for understanding the mechanisms by ...
  • Shabalina, Svetlana A.; Ogurtsov, Aleksey Y.; Spiridonov, Alexey Nikolaevich; Novichkov, Pavel S.; Spiridonov, Nikolay A.; Koonin, Eugene V. (Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2010-04)
    Comparison of expression levels and breadth and evolutionary rates of intronless and intron-containing mammalian genes shows that intronless genes are expressed at lower levels, tend to be tissue specific, and evolve ...
  • Dragoi, George; Tonegawa, Susumu (National Academy of Sciences (U.S.), 2013-05)
    The activity of ensembles of hippocampal place cells represents a hallmark of an animal’s spatial experience. The neuronal mechanisms that enable the rapid expression of novel place cell sequences are not entirely understood. ...
  • Frederick, Kendra K.; Debelouchina, Galia Tzvetanova; Kayatekin, Can; Dorminy, Tea; Jacavone, Angela; Griffin, Robert Guy; Lindquist, Susan (Elsevier, 2014-01)
    Yeast prions are self-templating protein-based mechanisms of inheritance whose conformational changes lead to the acquisition of diverse new phenotypes. The best studied of these is the prion domain (NM) of Sup35, which ...
  • Vieux (Kloss), Ellen; Wohlever, Matthew Lee; Chen, James Z.; Sauer, Robert T.; Baker, Tania (National Academy of Sciences (U.S.), 2013-05)
    Lon is an ATPase associated with cellular activities (AAA+) protease that controls cell division in response to stress and also degrades misfolded and damaged proteins. Subunits of Lon are known to assemble into ring-shaped ...
  • Triantafyllou, Christina; Brown, Emery N.; Whitfield-Gabrieli, Susan; Scholz, Jonathan; Saxe, Rebecca R. (Public Library of Science, 2009-03)
    In functional magnetic resonance imaging (fMRI) studies, a cortical region in the right temporo-parietal junction (RTPJ) is recruited when participants read stories about people's thoughts (‘Theory of Mind’). Both fMRI and ...
  • Gantz, Stephanie C.; Robinson, Brooks G.; Buck, David C.; Bunzow, James R.; Neve, Rachael L.; Williams, John T.; Neve, Kim A. (eLife Sciences Publications, Ltd., 2015-08)
    D2 autoreceptors regulate dopamine release throughout the brain. Two isoforms of the D2 receptor, D2S and D2L, are expressed in midbrain dopamine neurons. Differential roles of these isoforms as autoreceptors are poorly ...
  • Kim, Seokhee; Sauer, Robert T. (Cold Spring Harbor Laboratory Press, 2014-04)
    Intracellular proteases combat proteotoxic stress by degrading damaged proteins, but their activity must be carefully controlled to maintain cellular fitness. The activity of Escherichia coli DegP, a highly conserved ...
  • Golarai, Golijeh; Ghahremani, Dara G.; Eberhardt, Jennifer L.; Gabrieli, John D. E. (Frontiers Research Foundation, 2015-11)
    Several regions of the human brain respond more strongly to faces than to other visual stimuli, such as regions in the amygdala (AMG), superior temporal sulcus (STS), and the fusiform face area (FFA). It is unclear if these ...
  • McLaughlin, Nathan; Foster, Kelly A.; Edbauer, Dieter; Phillips, Marnie A.; Bolton, Andrew Donald; Constantine-Paton, Martha; Sheng, Morgan Hwa-Tze (Society for Neuroscience, 2010-02)
    NMDA receptors (NMDARs) are critical mediators of activity-dependent synaptic plasticity, but the differential roles of NR2A- versus NR2B-containing NMDARs have been controversial. Here, we investigate the roles of NR2A ...
  • Goard, Michael; Pho, Gerald N; Woodson, Jonathan; Sur, Mriganka (eLife Sciences Publications, Ltd., 2016-08)
    Mapping specific sensory features to future motor actions is a crucial capability of mammalian nervous systems. We investigated the role of visual (V1), posterior parietal (PPC), and frontal motor (fMC) cortices for ...
  • Sun, Chen; Kitamura, Takashi; Yamamoto, Jun; Martin, Jared; Kitch, Lacey J.; Schnitzer, Mark J.; Tonegawa, Susumu; Pignatelli di Spinazzola, Michele (National Academy of Sciences (U.S.), 2015-07)
    Entorhinal–hippocampal circuits in the mammalian brain are crucial for an animal’s spatial and episodic experience, but the neural basis for different spatial computations remain unknown. Medial entorhinal cortex layer II ...
  • Conlon, David; Fox, Jacob; Gasarch, William; Harris, David G.; Ulrich, Douglas; Zbarsky, Samuel (Society for Industrial and Applied Mathematics, 2015-03)
    Suppose that a and d are positive integers with a ≥ 2. Let h[subscript a,d](n) be the largest integer t such that any set of n points in R[superscript d] contains a subset of t points for which all the nonzero volumes of ...
  • Lusztig, George (American Mathematical Society (AMS), 2014-08)
    We define and study a correspondence between the set of distinguished G[superscript 0]-conjugacy classes in a fixed connected component of a reductive group G (with G[superscript 0] almost simple) and the set of (twisted) ...
  • Haslanger, Sally (Muse - Johns Hopkins University Press, 2015-03)
    Recent work on social injustice has focused on implicit bias as an important factor in explaining persistent injustice in spite of achievements on civil rights. In this paper, I argue that because of its individualism, ...
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