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Browsing MIT Open Access Articles by Title

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  • Agrawal, Prateek; Fan, JiJi; Reece, Matthew; Xue, Wei (Springer Berlin Heidelberg, 2017-06)
    Future hadron colliders will have a remarkable capacity to discover massive new particles, but their capabilities for precision measurements of couplings that can reveal underlying mechanisms have received less study. In ...
  • Montaño, Sherwin P.; Rice, Phoebe A.; Ling, Lorraine; Sauer, Robert T; Baker, Tania (Elsevier, 2015-03)
    ATP-dependent protein remodeling and unfolding enzymes are key participants in protein metabolism in all cells. How these often-destructive enzymes specifically recognize target protein complexes is poorly understood. Here, ...
  • Prelec, Drazen (Cambridge University Press, 2013)
    By Calvinist point of view, I refer to analysis focused on assessing the diagnostic significance of policy decisions, rather than establishing the direct consequences of decisions. Diagnostic significance refers to information ...
  • Linkov, Igor; Trump, Benjamin; Jin, David S.; Mazurczak, Marcin; Schreurs, Miranda (Springer, 2014-08)
    Background: The development of horizontal drilling and hydraulic fracturing methods has dramatically increased the potential for the extraction of previously unrecoverable natural gas. Nonetheless, the potential risks and ...
  • Gombolay, Matthew Craig; Gutierrez, Reymundo A.; Clarke, Shanelle G.; Sturla, Giancarlo F.; Shah, Julie A. (Springer Nature, 2015-07)
    In manufacturing, advanced robotic technology has opened up the possibility of integrating highly autonomous mobile robots into human teams. However, with this capability comes the issue of how to maximize both team ...
  • Amon, Angelika B.; Tyers, Mike (Elsevier Ltd., 2009-12)
    Cells must perpetually decide on three big choices in life: to grow, to divide or to die. These system-level decisions are the output of a complex and still very poorly understood molecular algorithm, which is built from ...
  • McShane, Blakeley B.; Chen, Chaoqun; Anderson, Eric T.; Simester, Duncan (Institute for Operations Research and the Management Sciences (INFORMS), 2016-03)
    We study the pass-through of wholesale price changes onto regular retail prices using an unusually detailed data set obtained from a major retailer. We model pass-through as a two-stage decision process that reflects both ...
  • Klann, Jeffrey G.; Szolovits, Peter; Downs, Stephen M.; Schadow, Gunther (Elsevier, 2013-12)
    Objective Reducing care variability through guidelines has significantly benefited patients. Nonetheless, guideline-based Clinical Decision Support (CDS) systems are not widely implemented or used, are frequently out-of-date, ...
  • Sandberg, Melanie J.; Simaiakis, Ioannis; Balakrishnan, Hamsa; Reynolds, Thomas G.; Hansman, Robert J., Jr. (Institute of Electrical and Electronics Engineers (IEEE), 2014-05)
    Airport surface congestion control has the potential to mitigate the increase in taxi times and fuel burn at major airports. One possible class of congestion control strategies predicts the departure throughput, and ...
  • Kharait, Sourabh; Hautaniemi, Sampsa; Wu, Shan; Iwabu, Akihiro; Lauffenburger, Douglas A.; Wells, Alan (BioMed Central Ltd, 2007-01)
    Background: Computational models of cell signaling networks typically are aimed at capturing dynamics of molecular components to derive quantitative insights from prior experimental data, and to make predictions concerning ...
  • Shaevitz, M. H.; Axani, Spencer Nicholas; Collin, Gabriel Lewis; Conrad, Janet; Spitz, Joshua B.; Wongjirad, Taritree (American Physical Society, 2015-11)
    “KPipe” is a proposed experiment which will study muon neutrino disappearance for a sensitive test of the Δm[superscript 2] ~ 1  eV[superscript 2] anomalies, possibly indicative of one or more sterile neutrinos. The ...
  • Huang, Junhua; Algeo, Thomas J.; Li, Chao; Zhou, Lian; Robinson, Andrew; Lyons, Timothy W.; Xie, Shucheng; Luo, Genming; Ono, Shuhei (Elsevier, 2014-12)
    Multiple-sulfur isotope compositions ([superscript 32]S, [superscript 33]S, [superscript 34]S and [superscript 36]S) were analyzed for paired carbonate-associated sulfate (CAS) and disseminated pyrite (PY) from the ∼1.6-Ga ...
  • Youngman, Matthew J.; Rogers, Zoe N.; Kim, Dennis H. (Public Library of Science, 2011-05)
    The decline in immune function with aging, known as immunosenescence, has been implicated in evolutionarily diverse species, but the underlying molecular mechanisms are not understood. During aging in Caenorhabditis elegans, ...
  • Tikekar, Mehul; Huang, Chao-Tsung; Sze, Vivienne; Juvekar, Chiraag Shashikant; Chandrakasan, Anantha P. (Springer-Verlag, 2014)
    This chapter provides an overview of the design challenges faced in the implementation of hardware HEVC decoders. These challenges can be attributed to the larger and diverse coding block sizes and transform sizes, the ...
  • Koster-Hale, Jorie; Saxe, Rebecca R.; Dungan, James; Young, Liane L. (National Academy of Sciences (U.S.), 2013-03)
    Intentional harms are typically judged to be morally worse than accidental harms. Distinguishing between intentional harms and accidents depends on the capacity for mental state reasoning (i.e., reasoning about beliefs and ...
  • Matthews, Gillian A.; Presbrey, Kara N.; Wichmann, Romy; Wildes, Craig P.; Nieh, Horng-An Edward; Allsop, Stephen Azariah; Leppla, Christopher Albert; Neve, Rachael L.; Tye, Kay; Matthews, Gillian A.; Presbrey, Kara N.; Wildes, Craig P. (Elsevier, 2015-01)
    The lateral hypothalamic (LH) projection to the ventral tegmental area (VTA) has been linked to reward processing, but the computations within the LH-VTA loop that give rise to specific aspects of behavior have been difficult ...
  • Pan, Wei; Altshuler, Yaniv; Pentland, Alex Paul (Institute of Electrical and Electronics Engineers (IEEE), 2012-09)
    In this paper, we study roles of social mechanisms in a financial system. Our data come from a novel on-line foreign exchange trading brokerage for individual investors, which also allows investors to form social network ...
  • Day, Mitchell L.; Delgutte, Bertrand (Society for Neuroscience, 2013-10)
    The strategies by which the central nervous system decodes the properties of sensory stimuli, such as sound source location, from the responses of a population of neurons are a matter of debate. We show, using the average ...
  • Jayaraman, Akila; Chandrasekaran, Aarthi; Viswanathan, Karthik; Raman, Rahul; Fox, James G.; Sasisekharan, Ram (Public Library of Science, 2012-02)
    Ferrets are widely used as animal models for studying influenza A viral pathogenesis and transmissibility. Human-adapted influenza A viruses primarily target the upper respiratory tract in humans (infection of the lower ...
  • Kwee, Patrick; Miller, John; Isogai, Tomoki; Barsotti, Lisa; Evans, Matthew J. (American Physical Society, 2014-09)
    Squeezed states of light have been successfully employed in interferometric gravitational-wave detectors to reduce quantum noise, thus becoming one of the most promising options for extending the astrophysical reach of the ...
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