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Browsing MIT Open Access Articles by Title

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  • Regev, Aviv; Immunological Genome Consortium (Nature Publishing Group, 2012-09)
    We assessed gene expression in tissue macrophages from various mouse organs. The diversity in gene expression among different populations of macrophages was considerable. Only a few hundred mRNA transcripts were selectively ...
  • Boissonneault, Katie; Henningsen, Brooks M; Bates, Stephen S; Robertson, Deborah L; Milton, Sean; Pelletier, Jerry; Hogan, Deborah A; Housman, David E; Housman, David E. (Biomed Central Ltd., 2013-11)
    Background: Pseudo-nitzschia multiseries Hasle (Hasle) (Ps-n) is distinctive among the ecologically important marine diatoms because it produces the neurotoxin domoic acid. Although the biology of Ps-n has been investigated ...
  • Spidlen, Josef; Barsky, Aaron; Breuer, Karin; Carr, Peter; Nazaire, Marc-Danie; Hill, Barbara A; Qian, Yu; Liefeld, Ted; Reich, Michael; Wilkinson, Peter; Scheuermann, Richard H; Sekaly, Rafick-Pierre; Brinkman, Ryan R; Hill, Barbara; Mesirov, Jill P. (BioMed Central Ltd, 2013-07)
    Background: Traditional flow cytometry data analysis is largely based on interactive and time consuming analysis of series two dimensional representations of up to 20 dimensional data. Recent technological advances have ...
  • Adida, Ben; Kohane, Isaac (BioMed Central Ltd, 2006-04)
    Background: Patient genomic data are rapidly becoming part of clinical decision making. Within a few years, full genome expression profiling and genotyping will be affordable enough to perform on every individual. The ...
  • Brown, Emery N.; Purdon, Patrick Lee; Van Dort, Christa (Annual Reviews, 2011-07)
    Placing a patient in a state of general anesthesia is crucial for safely and humanely performing most surgical and many nonsurgical procedures. How anesthetic drugs create the state of general anesthesia is considered a ...
  • Schiff, Nicholas D.; Brown, Emery N.; Lydic, Emily K. (New England Journal of Medicine, 2010-12)
    In the United States, nearly 60,000 patients per day receive general anesthesia for surgery.1 General anesthesia is a drug-induced, reversible condition that includes specific behavioral and physiological traits — ...
  • Brown, Emery N.; Lydic, Ralph; Schiff, Nicholas D. (New England Journal of Medicine, 2010-12)
    In the United States, nearly 60,000 patients per day receive general anesthesia for surgery.1 General anesthesia is a drug-induced, reversible condition that includes specific behavioral and physiological traits — ...
  • Kim, Justin; Movassaghi, Mohammad (American Chemical Society, 2010-09)
    A highly stereoselective and systematic strategy for the introduction of polysulfides in the synthesis of epipolythiodiketopiperazines is described. We report the first total synthesis of dimeric epitri- and epitetrathio ...
  • Braatz, Richard D.; Chen, Kejia; Vaidyanathan, Ramakrishnan; Seebauer, Edmund G. (American Institute of Physics (AIP), 2010-01)
    In many solids, diffusion of foreign atoms takes place primarily through highly mobile intermediate species that periodically exchange with atoms in the crystalline lattice. The governing reaction-diffusion equations include ...
  • Berger, Carola; Gainer, J.S.; Hewett, J.L.; Lillie, B.; Rizzo, T.G. (American Physical Society, 2009-11)
    We present the first detailed, large-scale study of the minimal supersymmetric standard model (MSSM) at the √s=500  GeV International Linear Collider (ILC), including full standard model backgrounds and detector simulation. ...
  • He, Xuhua; Lusztig, George (American Mathematical Society, 2012-01)
    Let G be a semisimple group over an algebraically closed field. Steinberg has associated to a Coxeter element w of minimal length r a subvariety V of G isomorphic to an affine space of dimension r which meets the regular ...
  • Demaine, Erik D.; Lubiw, Anna (Springer-Verlag, 2012)
    We present a new method for unfolding a convex polyhedron into one piece without overlap, based on shortest paths to a convex curve on the polyhedron. Our “sun unfoldings” encompass source unfolding from a point, source ...
  • Kedlaya, Kiran S.; Shao, Xuancheng (American Mathematical Society, 2009-01)
    In this paper, we present some generalizations of Gowers’s result about product-free subsets of groups. For any group G of order n, a subset A of G is said to be product-free if there is no solution of the equation ab = ...
  • Hwang, J. George; Lehn, Peter W.; Winkelnkemper, Manfred (Institute of Electrical and Electronics Engineers (IEEE), 2010-10)
    Within power systems, high-power pulsewidth-modulated ac-dc converters are used in flexible ac transmission systems controllers and for interfacing renewable energy sources to the grid. These converters traditionally ...
  • Grassl, Markus; Shor, Peter W.; Smith, Graeme; Smolin, John; Zeng, Bei (American Physical Society, 2009-05)
    We discuss the concept of generalized concatenated quantum codes. This generalized concatenation method provides a systematical way for constructing good quantum codes, both stabilizer codes and nonadditive codes. Using ...
  • Grassl, Markus; Zeng, Bei; Shor, Peter W. (Institute of Electrical and Electronics Engineers, 2009-08)
    We show how good quantum error-correcting codes can be constructed using generalized concatenation. The inner codes are quantum codes, the outer codes can be linear or nonlinear classical codes. Many new good codes are ...
  • Demaine, Erik D.; Price, Gregory N. (Springer-Verlag, 2009-09)
    A convex surface that is flat everywhere but on finitely many smooth curves (or seams) and points is a seam form. We show that the only creases through the flat components of a seam form are either between vertices or ...
  • Iadecola, Thomas; Chamon, Claudio; Jackiw, Roman; Pi, So-Young (American Physical Society, 2013-09)
    Driven condensed matter systems consistently pose substantial challenges to theoretical understanding. Progress in the study of such systems has been achieved using the Floquet formalism, but certain aspects of this approach ...
  • Yu, Xiangyao; Ren, Ling; Devadas, Srinivas; Fletcher, Christopher Wardlaw; van Dijk, Marten (Association for Computing Machinery (ACM), 2013-11)
    This paper investigates secure ways to interact with tamper-resistant hardware leaking a strictly bounded amount of information. Architectural support for the interaction mechanisms is studied and performance implications ...
  • Domínguez-García, A. D.; Schindall, Joel E.; Kassakian, John G. (Institute of Electrical and Electronics Engineers, 2009-05)
    This paper proposes a fault coverage model for linear time-invariant (LTI) systems subject to uncertain input. A state-space representation, defined by the state-transition matrix, and the input matrix, is used to represent ...
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