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Browsing MIT Open Access Articles by Title

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  • Le, Tung Ba Khanh; Imakaev, Maksim Viktorovich; Mirny, Leonid A.; Laub, Michael T. (American Association for the Advancement of Science (AAAS), 2013-10)
    Chromosomes must be highly compacted and organized within cells, but how this is achieved in vivo remains poorly understood. We report the use of chromosome conformation capture coupled with deep sequencing (Hi-C) to map ...
  • Bayro, Marvin J.; Griffin, Robert Guy; Maly, Thorsten; Birkett, Neil R.; Dobson, Christopher M.; MacPhee, Cait E. (American Chemical Society (ACS), 2010-07)
    The SH3 domain of the PI3 kinase (PI3-SH3 or PI3K-SH3) readily aggregates into fibrils in vitro and has served as an important model system in the investigation of the molecular properties and mechanism of formation of ...
  • Harman, Michelle; Li, Xingde; Pitris, Costas; Ghanta, Ravi; Fujimoto, James G.; Stamper, Debra L.; Brezinski, Mark E.; Martin, Scott (BioMed Central Ltd, 2005-01)
    This study demonstrates the first real-time imaging in vivo of human cartilage in normal and osteoarthritic knee joints at a resolution of micrometers, using optical coherence tomography (OCT). This recently developed ...
  • Leeb, Steven B.; Paris, James; Avestruz, Al-Thaddeus; Wichakool, Warit (Institute of Electrical and Electronics Engineers, 2010-02)
    This paper presents a high-resolution, physically-windowed sensor architecture that is well-suited for energy scorekeeping and diagnostic applications. The sensor can track a large-scale main signal while capturing small-scale ...
  • Wichakool, Warit; Paris, James; Avestruz, Al-Thaddeus; Leeb, Steven B. (Institute of Electrical and Electronics Engineers (IEEE), 2010-03)
    This paper presents a high-resolution, physically-windowed sensor architecture that is well-suited for energy scorekeeping and diagnostic applications. The sensor can track a large-scale main signal while capturing small-scale ...
  • Aoki, Wako; Beers, Timothy C.; Lee, Young Sun; Honda, Satoshi; Ito, Hiroko; Takada-Hidai, Masahide; Frebel, Anna L.; Suda, Takuma; Fujimoto, Masayuki Y.; Carollo, Daniela; Sivarani, Thirupathi (IOP Publishing, 2012-12)
    Chemical compositions are determined based on high-resolution spectroscopy for 137 candidate extremely metal-poor (EMP) stars selected from the Sloan Digital Sky Survey (SDSS) and its first stellar extension, the Sloan ...
  • Gayou, Olivier; Monaghan, Peter; Qiang, Yi (American Physical Society, 2009-11)
    An experimental study of the 16O(e,e′K+)Λ16N [superscript 16 O (e, e prime K superscript +) superscript 16 subscript lambda N] reaction has been performed at Jefferson Lab. A thin film of falling water was used as a target. ...
  • Fang, Taotao; Canizares, Claude R.; Marshall, Herman Lee (IOP Publishing, 2005-01)
    We present a survey of six low- to moderate-redshift quasars with Chandra and XMM-Newton. The primary goal is to search for the narrow X-ray absorption lines produced by highly ionized metals in the warm-hot intergalactic ...
  • Kim, Kyoohyun; Yoon, HyeOk; Dao, Ming; Park, YongKeun; Diez Silva, Monica; Dasari, Ramachandra Rao (SPIE, 2013-06)
    We present high-resolution optical tomographic images of human red blood cells (RBC) parasitized by malaria-inducing Plasmodium falciparum (Pf)-RBCs. Three-dimensional (3-D) refractive index (RI) tomograms are reconstructed ...
  • Chen, Yu; Andrews, Peter M.; Aguirre, Aaron D.; Schmitt, Joseph M.; Fujimoto, James G. (SPIE, 2007-05)
    Optical coherence tomography (OCT) is an emerging medical imaging technology that enables high-resolution, noninvasive, cross-sectional imaging of microstructure in biological tissues in situ and in real time. When combined ...
  • Kashif, Faisal Mahmood; Shafi, Imran; Ahmad, Jamil; Shah, Syed Ismail; Ikram, Ataul Aziz; Khan, Adnan Ahmad; Bashir, Sajid (European Association for Signal Processing / Hindawi, 2010-01)
    his work evaluates the performance of high-resolution quadratic time-frequency distributions (TFDs) including the ones obtained by the reassignment method, the optimal radially Gaussian kernel method, the t-f autoregressive ...
  • Regev, Aviv; Brar, Gloria A.; Yassour, Moran; Friedman, Nir; Ingolia, Nicholas T.; Weissman, Jonathan S. (American Association for the Advancement of Science (AAAS), 2011-12)
    Meiosis is a complex developmental process that generates haploid cells from diploid progenitors. We measured messenger RNA (mRNA) abundance and protein production through the yeast meiotic sporulation program and found ...
  • Ragan, Timothy; Sylvan, Jeremy D.; Kim, Ki Hean; Huang, Hayden; Bahlmann, Karsten; Lee, Richard T.; So, Peter T. C. (SPIE, 2007-02)
    Three-dimensional (3-D) tissue imaging offers substantial benefits to a wide range of biomedical investigations from cardiovascular biology, diabetes, Alzheimer’s disease to cancer. Two-photon tissue cytometry is a novel ...
  • Zhekov, Svetozar A.; McCray, Richard; Dewey, Dan; Canizares, Claude R.; Borkowski, Kazimierz J.; Burrows, David N.; Park, Sangwook (American Astronomical Society, 2009-02)
    We present an extended analysis of the deep Chandra LETG and HETG observations of the supernova remnant 1987A (SNR 1987A) carried out in 2007. The global fits to the grating spectra show that the temperature of the X-ray ...
  • Schulz, Norbert S.; Gu, Ming F.; Nowak, Michael A.; Canizares, Claude R. (American Astronomical Society, 2009-04)
    High-resolution X-ray absorption spectroscopy is a powerful diagnostic tool for probing chemical and physical properties of the interstellar medium (ISM) at various phases. We present detections of K transition absorption ...
  • Marshall, Herman Lee; Canizares, Claude R.; Schulz, Norbert S. (IOP Publishing, 2002-01)
    We present observations of SS 433 using the Chandra High Energy Transmission Grating Spectrometer. Many emission lines of highly ionized elements are detected with relativistic blue and red Doppler shifts. The lines are ...
  • Wynn, Charles M.; Palmacci, Stephen; Clark, Michelle L.; Kunz, Roderick R. (SPIE, 2013-08)
    Lincoln Laboratory of Massachusetts Institute of Technology has developed a technique known as dynamic photoacoustic spectroscopy (DPAS) that could enable remote detection of trace gases via a field-portable laser-based ...
  • Schulein, Robert T.; Grein, Matthew E.; Yoon, Jung Uk; Lennon, Donna M.; Geis, Michael W.; Lyszczarz, Theodore M.; Spector, Steven Jay; Zhou, G. R.; Smith, Henry Ignatius; Ram, Rajeev J.; Popovic, Milos; Perrott, Michael H.; Park, M.; Orcutt, Jason Scott; Motamedi, Ali R.; Kim, M.; Kim, J.; Khilo, Anatol M.; Kaertner, Franz X.; Ippen, Erich P.; Hoyt, Judy L.; Gan, F.; DiLello, Nicole Ann; Dahlem, Marcus Vinicius Sobral; Chen, J.; Byun, Hyunil; Birge, Jonathan R.; Araghchini, Mohammad; Amatya, Reja; Holzwarth, Charles W.; Shmulovich, J.; Hanjani, A.; Frolov, S. (The International Society for Optical Engineering, 2009-02)
    Sampling rates of high-performance electronic analog-to-digital converters (ADC) are fundamentally limited by the timing jitter of the electronic clock. This limit is overcome in photonic ADC's by taking advantage of the ...
  • Karaman, Sertac; Frazzoli, Emilio (Institute of Electrical and Electronics Engineers, 2012-05)
    Inspired by birds flying through cluttered environments such as dense forests, this paper studies the theoretical foundations of high-speed motion through a randomly-generated obstacle field. Assuming that the locations ...
  • Chen, Xiangyu; Lee, Kyeong-Jae; Akinwande, Deji; Close, Gael F.; Yasuda, Shinichi; Paul, Bipul; Fujita, Shinobu; Kong, Jing; Wong, H. -S. Philip (Institute of Electrical and Electronics Engineers (IEEE), 2010-03)
    We have successfully experimentally integrated graphene interconnects with commercial 0.25 ¿m technology CMOS ring oscillator circuit using conventional fabrication techniques, and demonstrated high speed on-chip graphene ...
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