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Browsing MIT Open Access Articles by Title

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  • Schultz, David; Liskov, Barbara H. (Association for Computing Machinery (ACM), 2013-04)
    Numerous sensitive databases are breached every year due to bugs in applications. These applications typically handle data for many users, and consequently, they have access to large amounts of confidential information. This ...
  • Grodzinsky, Alan J.; Wheeler, Cameron A.; Jafarzadeh, Seyed R.; Rocke, David M. (Elsevier Ltd., 2009-02)
    Objective To determine changes in chondrocyte transcription of a range of anabolic, catabolic and signaling genes following simultaneous treatment of cartilage with Insulin-like growth factor-1 (IGF-1) and ramp-and-hold ...
  • del Alamo, Jesus A.; Kim, Dae-Hyun; Kim, Tae-Woo; Jin, Donghyun; Antoniadis, Dimitri A. (Institute of Electrical and Electronics Engineers (IEEE), 2011-08)
    The ability of Si CMOS to continue to scale down transistor size while delivering enhanced logic performance has recently come into question. An end to Moore's Law threatens to bring to a halt the microelectronics revolution: ...
  • Christoffel, Daniel J.; Golden, Sam A.; Dumitriu, Dani; Robison, Alfred J.; Janssen, William G.; Ahn, H. Francisca; Krishnan, Vaishnav; Reyes, Cindy M.; Han, Ming-Hu; Ables, Jessica L.; Eisch, Amelia J.; Dietz, David M.; Ferguson, Deveroux; Neve, Rachael L.; Greengard, Paul; Kim, Yong; Morrison, John H.; Russo, Scott J. (Society for Neuroscience, 2011-01)
    The neurobiological underpinnings of mood and anxiety disorders have been linked to the nucleus accumbens (NAc), a region important in processing the rewarding and emotional salience of stimuli. Using chronic social defeat ...
  • Knepper, Ross A.; Layton, Todd; Romanishin, John William; Rus, Daniela L. (Institute of Electrical and Electronics Engineers (IEEE), 2013-05)
    We present an automated assembly system that directs the actions of a team of heterogeneous robots in the completion of an assembly task. From an initial user-supplied geometric specification, the system applies reasoning ...
  • Howlett, Meegan; Chalinor, Heather V.; Buzzelli, Jon N.; Nguyen, Nhung; van Driel, Ian R.; Bell, Katrina M.; Dimitriadis, Eva; Menheniott, Trevelyan R; Giraud, Andrew S.; Judd, Louise M.; Fox, James G. (BMJ Publishing Group, 2011-12)
    Background and Aims IL-is important in gastric damage, mucosal repair and gastric cancer progression. We analysed IL-11 expression in H.pylori infected mouse stomach, the site of gastric IL-11 expression in mice and humans, ...
  • Maier, Lisa M.; Lowe, Christopher E.; Cooper, Jason; Downes, Kate; Anderson, David E.; Severson, Christopher; Clark, Pamela M.; Healy, Brian; Walker, Neil; Aubin, Cristin; Oksenberg, Jorge R.; Hauser, Stephen L.; Compston, Alistair; Sawcer, Stephen; De Jager, Philip L.; Wicker, Linda S.; Todd, John A.; Hafler, David A. (Public Library of Science, 2009-01)
    Multiple sclerosis (MS) and type 1 diabetes (T1D) are organ-specific autoimmune disorders with significant heritability, part of which is conferred by shared alleles. For decades, the Human Leukocyte Antigen (HLA) complex ...
  • Ernst, Jason M.; Ghanem, Louis; Bar-Joseph, Ziv; McNamara, Michael; Brown, Jason; Steinman, Richard A. (Public Library of Science, 2009-10)
    The growth factor interleukin-3 (IL-3) promotes the survival and growth of multipotent hematopoietic progenitors and stimulates myelopoiesis. It has also been reported to oppose terminal granulopoiesis and to support ...
  • Bao, Jack; Pan, Jun; Wang, Jiang (American Finance Association/John Wiley & Sons, Inc., 2011-06)
    This paper examines the illiquidity of corporate bonds and its asset-pricing implications. Using transactions data from 2003 to 2009, we show that the illiquidity in corporate bonds is substantial, significantly greater ...
  • Lo, Andrew W.; Khandani, Amir Ehsan (World Scientific, 2011-06)
    We establish a link between illiquidity and positive autocorrelation in asset returns among a sample of hedge funds, mutual funds, and various equity portfolios. For hedge funds, this link can be confirmed by comparing the ...
  • Silbey, Susan S.; Agrawal, Tanu (World Scientific, 2011-01)
    How do laws and regulations govern the activities of large, decentralized, and often geographically dispersed organizations? Under conditions of loose coupling, how does the organization coordinate action and know what it ...
  • Redaelli, F.; Santambrogio, Marco Domenico; Memik, S. Ogrenci (Hindawi Publishing, 2009-09)
    This work proposes an exact ILP formulation for the task scheduling problem on a 2D dynamically and partially reconfigurable architecture. Our approach takes physical constraints of the target device that is relevant for ...
  • Kamentsky, Lee; Liu, Zihan H; Riklin-Raviv, Tammy; Conery, Annie L; O'Rourke, Eyleen J; Sokolnicki, Katherine L; Visvikis, Orane; Ljosa, Vebjorn; Irazoqui, Javier E; Golland, Polina; Ruvkun, Gary; Ausubel, Frederick M; Carpenter, Anne E; Wahlby, Carolina (Nature Publishing Group, 2012-04)
    We present a toolbox for high-throughput screening of image-based Caenorhabditis elegans phenotypes. The image analysis algorithms measure morphological phenotypes in individual worms and are effective for a variety of ...
  • Bae, Soonmin; Cho, Peter L.; Durand, Fredo (The International Society for Optical Engineering, 2009-05)
    We extend recent automated computer vision algorithms to reconstruct the global three-dimensional structures for photos and videos shot at fixed points in outdoor city environments. Mosaics of digital stills and embedded ...
  • Lanman, Douglas; Mohan, Ankit; Hiura, Shinsaku; Raskar, Ramesh (Institute of Electrical and Electronics Engineers, 2010-08)
    We propose a novel camera setup in which both the lens and the sensor are perturbed during the exposure. We analyze the defocus effects produced by such a setup, and use it to demonstrate new methods for simulating a lens ...
  • Shenton, Martha E.; Balci, Serdar K.; Sabuncu, Mert R.; Golland, Polina (Institute of Electrical and Electronics Engineers, 2009-08)
    We present iCluster, a fast and efficient algorithm that clusters a set of images while co-registering them using a parameterized, nonlinear transformation model. The output of the algorithm is a small number of template ...
  • Khosla, Aditya; Xiao, Jianxiong; Isola, Phillip John; Torralba, Antonio; Oliva, Aude (Association for Computing Machinery, 2012)
    When glancing at a magazine, or browsing the Internet, we are continuously being exposed to photographs. However, not all images are equal in memory; some stitch to our minds, while others are forgotten. In this paper we ...
  • Kovac, Joseph; Gerardin, Ylaine; Voldman, Joel (Wiley Blackwell, 2012-11)
    Using photopatterned hydrogels and selective cell encapsulation, populations of adherent cells are examined using microscopy and sorted into viable sub-populations predicated on their imaged phenotypes. The inexpensive ...
  • Cho, Taeg Sang; Zitnick, C. Lawrence; Joshi, Neel; Kang, Sing Bing; Szeliski, Richard; Freeman, William T. (Institute of Electrical and Electronics Engineers (IEEE), 2011-08)
    The restoration of a blurry or noisy image is commonly performed with a MAP estimator, which maximizes a posterior probability to reconstruct a clean image from a degraded image. A MAP estimator, when used with a sparse ...
  • Masters, Barry R. (Society of Photo-optical Instrumentation Engineers, 2011-03)
    Imaging: A Laboratory Manual Rafael Yuste, Editor 952 pages; ISBN 978-087969-36-9, Cold Spring Harbor Laboratory Press,Woodbury, NewYork (2011), $165 paperback. Reviewed by Barry R. Masters, Visiting Scientist, ...
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