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Browsing MIT Open Access Articles by Title

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  • Zheng, Tengfei; Nolan, Elizabeth M. (American Chemical Society (ACS), 2014-06)
    The design, synthesis, and characterization of enterobactin–antibiotic conjugates, hereafter Ent-Amp/Amx, where the β-lactam antibiotics ampicillin (Amp) and amoxicillin (Amx) are linked to a monofunctionalized enterobactin ...
  • Thomson, John M.; Hansen, Richard; Berry, Susan H.; Hope, Mairi E.; Murray, Graeme I.; Mukhopadhya, Indrani; McLean, Mairi H.; Shen, Zeli; Fox, James G.; El-Omar, Emad; Hold, Georgina L. (Public Library of Science, 2011-02)
    Background Changes in bacterial populations termed “dysbiosis” are thought central to ulcerative colitis (UC) pathogenesis. In particular, the possibility that novel Helicobacter organisms play a role in human UC has ...
  • Muzhikyan, Aramazd; Farid, Amro M.; Youcef-Toumi, Kamal (Institute of Electrical and Electronics Engineers (IEEE), 2015-03)
    In recent years, renewable energy has developed to address energy security and climate change drivers. However, as energy resources, they possess a variable and uncertain nature that significantly complicates grid balancing ...
  • Muzhikyan, Aramazd; Farid, Amro M.; Youcef-Toumi, Kamal (Institute of Electrical and Electronics Engineers (IEEE), 2015-03)
    In recent years, an extensive academic and industrial literature has been developed to determine how much such variable energy resources (VERs) may be integrated and how to best mitigate their impacts. While certainly ...
  • Trivedi, Mehul A.; Stoub, Travis R.; Murphy, Christopher M.; George, Sarah; deToledo-Morrell, Leyla; Shah, Raj C.; Gabrieli, Susan; Gabrieli, John D. E.; Stebbins, Glenn T. (Springer-Verlag, 2011-02)
    The present study examined the relationship between entorhinal cortex and hippocampal volume with fMRI activation during episodic memory function in elderly controls with no cognitive impairment and individuals with amnesic ...
  • Huang, Kenneth G.; Murray, Fiona E. (Elsevier, 2010-06)
    We re-conceptualize the role of science policy makers, envisioning and illustrating their move from being simple investors in scientific projects to entrepreneurs who create the conditions for entrepreneurial experiments ...
  • Chen, Hui; Miao, Jianjun; Wang, Neng (Oxford University Press, 2010-11)
    We develop a dynamic incomplete-markets model of entrepreneurial firms, and demonstrate the implications of nondiversifiable risks for entrepreneurs' interdependent consumption, portfolio allocation, financing, investment, ...
  • Byers, Jeffery A.; Jamison, Timothy F. (National Academy of Sciences (U.S.), 2013-09)
    Despite the myriad of selective enzymatic reactions that occur in water, chemists have rarely capitalized on the unique properties of this medium to govern selectivity in reactions. Here we report detailed mechanistic ...
  • Faghfoor Maghrebi, Mohammad; Kantor, Yacov; Kardar, Mehran (IOP Publishing, 2011-12)
    We consider polymers attached to the tip of a cone, and the resulting force due to entropy loss on approaching a plate (or another cone). At separations shorter than the polymer radius of gyration Rg, the only relevant ...
  • Sinatra, Roberta; Szell, Michael (MDPI AG, 2014-01)
    Using mobile phone records and information theory measures, our daily lives have been recently shown to follow strict statistical regularities, and our movement patterns are, to a large extent, predictable. Here, we apply ...
  • Sze, Vivienne; Marpe, Detlev (Springer-Verlag, 2014)
    Context-Based Adaptive Binary Arithmetic Coding (CABAC) is a method of entropy coding first introduced in H.264/AVC and now used in the latest High Efficiency Video Coding (HEVC) standard. While it provides high coding ...
  • Mistry, Karan Hemant; McGovern, Ronan Killian; Thiel, Gregory P.; Summers, Edward K.; Zubair, Syed M.; Lienhard, John H. (MDPI Publishing, 2011-09)
    Increasing global demand for fresh water is driving the development and implementation of a wide variety of seawater desalination technologies. Entropy generation analysis, and specifically, Second Law efficiency, is an ...
  • Lienhard, John H.; Thiel, Gregory Parker (Elsevier, 2012-05)
    The physical mechanisms of entropy generation in a condenser with high fractions of noncondensable gases are examined using scaling and boundary layer techniques, with the aim of defining a criterion for minimum entropy ...
  • Lienhard, John H.; Zubair, Syed M.; Narayan, G. Prakash (Elsevier, 2010-06)
    This paper details a simple procedure by which the entropy generation in simultaneous heat and mass exchange devices can be minimized. Effectiveness for these devices is defined and a new parameter, ‘modified heat capacity ...
  • Mistry, Karan Hemant; Chung, Hyung; Warsinger, David Elan Martin; Nayar, Kishor Govind; Lienhard, John H.; Chung, Hyung Won (MDPI AG, 2015-10)
    Powering desalination by waste heat is often proposed to mitigate energy consumption and environmental impact; however, thorough technology comparisons are lacking in the literature. This work numerically models the ...
  • Moon, SangJun; Gurkan, Umut Atakan; Blander, Jeffrey; Fawzi, Wafaie W.; Aboud, Said; Mugusi, Ferdinand; Kuritzkes, Daniel R.; Demirci, Utkan (Public Library of Science, 2011-04)
    Background CD4+ T-lymphocyte count (CD4 count) is a standard method used to monitor HIV-infected patients during anti-retroviral therapy (ART). The World Health Organization (WHO) has pointed out or recommended that a ...
  • Pisania, Anna; Papas, Klearchos K.; Powers, Daryl E.; Rappel, Michael J.; Omer, Abdulkadir; Bonner-Weir, Susan; Weir, Gordon C.; Colton, Clark K. (Nature Publishing Group, 2010-08)
    Islet enumeration in impure preparations by conventional dithizone staining and visual counting is inaccurate and operator dependent. We examined nuclei counting for measuring the total number of cells in islet preparations, ...
  • Chiu, C. S.; Ignarra, Christina; Bugel, Leonard G.; Chen, H.; Conrad, Janet; Jones, Benjamin James Poyner; Katori, Teppei; Moult, Ian James (Institute of Physics Publishing, 2012-07)
    The scintillation detection systems of liquid argon time projection chambers (LArTPCs) require wavelength shifters to detect the 128 nm scintillation light produced in liquid argon. Tetraphenyl butadiene (TPB) is a fluorescent ...
  • Brooks, Zanzile; Ulm, Franz-Josef; Einstein, Herbert H. (Springer-Verlag, 2013-03)
    This study explores the interaction between crack initiation and nanomechanical properties in the crack-tip fracture process zone of Carrara marble. Specimens with preexisting cracks were loaded in a uniaxial testing machine ...
  • Acemoglu, Daron; Aghion, Philippe; Bursztyn, Leonardo; Hemous, David (American Economic Association, 2012-02)
    This paper introduces endogenous and directed technical change in a growth model with environmental constraints. A unique final good is produced by combining inputs from two sectors. One of these sectors uses “dirty” ...
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