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Browsing MIT Open Access Articles by Title

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  • Abbott, Timothy G.; Burr, Michael A.; Chan, Timothy M.; Demaine, Erik D.; Demaine, Martin L.; Hugg, John; Kane, Daniel; Langerman, Stefan; Nelson, Jelani; Rafalin, Eynat; Seyboth, Kathryn; Yeung, Vincent (Elsevier, 2009-01)
    We design efficient data structures for dynamically maintaining a ham-sandwich cut of two point sets in the plane subject to insertions and deletions of points in either set. A ham-sandwich cut is a line that simultaneously ...
  • Waite, Janelle C.; Leiner, Ingrid; Lauer, Peter; Rae, Chris S.; Barbet, Gaetan; Zheng, Huan; Portnoy, Daniel A.; Pamer, Eric G.; Dustin, Michael L. (Public Library of Science, 2011-03)
    Host defense against the intracellular pathogen Listeria monocytogenes (Lm) requires innate and adaptive immunity. Here, we directly imaged immune cell dynamics at Lm foci established by dendritic cells in the subcapsular ...
  • Hassan, Musa A.; Good, Barbara; Hanrahan, James P.; Campion, Deirdre; Sayers, Gearoid; Mulcahy, Grace; Sweeney, Torres (BioMed Central Ltd, 2011-03)
    Suffolk sheep carrying the DRB1*1101 (previously referred to as-DRB1*0203 or G2) allele have been reported to show increased resistance to natural Teladorsagia circumcincta infection compared to non-carriers. The objective ...
  • Hoffmann, Henry Christian; Sidiroglou, Stelios; Carbin, Michael James; Misailovic, Sasa; Agarwal, Anant (Association for Computing Machinery (ACM), 2011-03)
    We present PowerDial, a system for dynamically adapting application behavior to execute successfully in the face of load and power fluctuations. PowerDial transforms static configuration parameters into dynamic knobs that ...
  • Brockman, Irene Marie; Prather, Kristala L. Jones (Elsevier, 2014-12)
    Control of native enzyme levels is important when optimizing strains for overproduction of heterologous compounds. However, for many central metabolic enzymes, static knockdown results in poor growth and protein expression. ...
  • Choudhury, Charisma F.; Abou-Zeid, Maya; Ben-Akiva, Moshe E. (Elsevier, 2010-01)
    Planning is an integral part of many behavioural aspects related to transportation: residential relocation, activity and travel scheduling, route choice, etc. People make plans and then select actions to execute those ...
  • Yamanaka, Yvonne J.; Love, J. Christopher; Gierahn, Todd Michael (Elsevier, 2012-11)
    Activated T cells have classically been thought to progress unidirectionally through discrete phenotypic states and differentiate into static lineages. It is increasingly evident, however, that T cells exhibit much more ...
  • Grodzinsky, Alan J.; Lee, BoBae; Han, Lin; Frank, Eliot H.; Ortiz, Christine; Grodzinsky, Alan J. (Elsevier Ltd., 2010-02)
    The success of cell-based tissue engineering approaches in restoring biological function will be facilitated by a comprehensive fundamental knowledge of the temporal evolution of the structure and properties of the newly ...
  • Toikka, Juuso; Pavan, Alessandro; Segal, Ilya (The Econometric Society, 2014-03)
    We study mechanism design in dynamic quasilinear environments where private information arrives over time and decisions are made over multiple periods. We make three contributions. First, we provide a necessary condition ...
  • Borau, Carlos; Kamm, Roger Dale (Public Library of Science, 2012-11)
    Cells modulate themselves in response to the surrounding environment like substrate elasticity, exhibiting structural reorganization driven by the contractility of cytoskeleton. The cytoskeleton is the scaffolding structure ...
  • Brockman, Irene Marie; Jones, Kristala L. (Wiley Blackwell, 2015-09)
    Metabolic engineering strategies have enabled improvements in yield and titer for a variety of valuable small molecules produced naturally in microorganisms, as well as those produced via heterologous pathways. Typically, ...
  • Karanfil, Ozge; Sterman, John (BioMed Central, 2015-08)
    Implications of widespread mammography screening remain controversial, and major health organizations in the US adopt different guidelines reflecting significant variations in actual practice. Literature suggests that ...
  • Kim, Min-Cheol; Neal, Devin M.; Kamm, Roger Dale; Asada, Harry (Public Library of Science, 2013-02)
    An integrative cell migration model incorporating focal adhesion (FA) dynamics, cytoskeleton and nucleus remodeling, actin motor activity, and lamellipodia protrusion is developed for predicting cell spreading and migration ...
  • Kanoria, Yash; Anderson, Ross Michael; Ashlagi, Itai; Gamarnik, David (Society for Industrial and Applied Mathematics (SIAM), 2015)
    We consider the problem of efficient operation of a barter exchange platform for indivisible goods. We introduce a dynamic model of barter exchange where in each period one agent arrives with a single item she wants to ...
  • Ghaffarzadegan, Navid; Ebrahimvandi, Alireza; Jalali, Seyed Mohammad Javad (Public Library of Science, 2016-10)
    Post-traumatic stress disorder (PTSD) stands out as a major mental illness; however, little is known about effective policies for mitigating the problem. The importance and complexity of PTSD raise critical questions: What ...
  • Smith, Stephen L.; Bullo, Francesco; Pavone, Marco; Frazzoli, Emilio (Institute of Electrical and Electronics Engineers, 2009-07)
    In this paper we study a dynamic vehicle routing problem in which there are multiple vehicles and multiple classes of demands. Demands of each class arrive in the environment randomly over time and require a random amount ...
  • Vasquez, Claudia G.; Tworoger, Michael B.; Martin, Adam C. (Rockefeller University Press, 2014-08)
    Apical constriction is a cell shape change that promotes epithelial bending. Activation of nonmuscle myosin II (Myo-II) by kinases such as Rho-associated kinase (Rok) is important to generate contractile force during apical ...
  • Bierlaire, Michel; Osorio Pizano, Carolina; Flotterod, Gunnar (Elsevier, 2011-05)
    We present a dynamic network loading model that yields queue length distributions, accounts for spillbacks, and maintains a differentiable mapping from the dynamic demand on the dynamic queue lengths. The model also captures ...
  • Grubb, Michael D. (Elsevier, 2012-01)
    Recent research highlights the importance of biased expectations and inattention for nonlinear pricing in dynamic environments. Findings are: (1) Three-part tariffs, such as cellular service contracts, exploit consumer ...
  • Bajaj, Vikram S.; Farrar, C. T.; Hornstein, Melissa K.; Mastovsky, Ivan; Vieregg, Jeffrey; Bryant, Jeffrey A.; Elena, B.; Kreischer, K. E.; Temkin, Richard J.; Griffin, Robert Guy (Elsevier, 2011-12)
    In this communication, we report enhancements of nuclear spin polarization by dynamic nuclear polarization (DNP) in static and spinning solids at a magnetic field strength of 9 T (250 GHz for g = 2 electrons, 380 MHz for ...
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