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Browsing MIT Open Access Articles by Title

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  • Cassa, Christopher A.; Savage, Sarah K.; Taylor, Patrick L.; Green, Robert C.; McGuire, Amy L.; Mandl, Kenneth D. (Cold Spring Harbor Laboratory Press, 2011-12)
    There is an emerging consensus that when investigators obtain genomic data from research participants, they may incur an ethical responsibility to inform at-risk individuals about clinically significant variants discovered ...
  • Hidalgo, Cesar A. (Springer International Publishing, 2016-07)
    During decades the study of networks has been divided between the efforts of social scientists and natural scientists, two groups of scholars who often do not see eye to eye. In this review I present an effort to mutually ...
  • Armoundas, Antonis A. (Institute of Electrical and Electronics Engineers, 2009-08)
    Electrocardiographic alternans is known to predispose to increased susceptibility to life threatening arrhythmias and sudden cardiac death. While this decreased level of cardiac electrical stability is often due to the ...
  • Eisenstein, Jacob; Barzilay, Regina; Davis, Randall (Association for Computing Machinery (ACM), 2008)
    Coverbal gesture provides a channel for the visual expression of ideas. While some gestural emblems have culturally predefined forms (e.g., "thumbs up"), the relationship between gesture and meaning is, in general, not ...
  • Kirkpatrick, J. Davy; Looper, Dagny L.; Burgasser, Adam J.; Schurr, Steven D.; Cutri, Roc M.; Cushing, Michael C.; Cruz, Kelle L.; Sweet, Anne C.; Knapp, Gillian R.; Barman, Travis S.; Bochanski, John J.; Roellig, Thomas L.; McLean, Ian S.; McGovern, Mark R.; Rice, Emily L. (American Astronomical Society, 2010-09)
    We have conducted a 4030 deg[superscript 2] near-infrared proper motion survey using multi-epoch data from the Two Micron All-Sky Survey (2MASS). We find 2778 proper motion candidates, 647 of which are not listed in SIMBAD. ...
  • Zhao, Qing; Xie, Lisi; Kulik, Heather Janine (American Chemical Society (ACS), 2015-09)
    We employ high-temperature ab initio molecular dynamics (AIMD) as a sampling approach to discover low-energy, semiconducting, indium phosphide nanostructures. Starting from under-coordinated models of InP (e.g. a single ...
  • Kolb, Brian; Lentz, Levi Carl; Kolpak, Alexie M. (Nature Publishing Group, 2017-04)
    Modern ab initio methods have rapidly increased our understanding of solid state materials properties, chemical reactions, and the quantum interactions between atoms. However, poor scaling often renders direct ab initio ...
  • Coulter, Bob; Perry, Judy; Klopfer, Eric; Sheldon, Joshua (Cambridge University Press, 2012-08)
    February 12, 2100: Walking down by the river’s shore it is hard to believe that as recently as a hundred years ago this bank of the river was dry l and. Today all of this land is frequently under water as a result of ...
  • Danford, Timothy William; Dowell, Robin D.; Agarwala, Sundeep; Grisafi, Paula; Fink, Gerald R.; Gifford, David K. (Springer Berlin/Heidelberg, 2010-05)
    STEREO is a novel algorithm that discovers cis-regulatory RNA interactions by assembling complete and potentially overlapping same-strand RNA transcripts from tiling expression data. STEREO first identifies coherent segments ...
  • Demirbas, Murat; Bayir, Murat Ali; Eagle, Nathan N. (Institute of Electrical and Electronics Engineers, 2009-10)
    Mobility path information of cellphone users play a crucial role in a wide range of cellphone applications, including context-based search and advertising, early warning systems, city-wide sensing applications such as air ...
  • Isola, Phillip John; Lim, Joseph Jaewhan; Adelson, Edward H (Institute of Electrical and Electronics Engineers (IEEE), 2015-10)
    Objects in visual scenes come in a rich variety of transformed states. A few classes of transformation have been heavily studied in computer vision: mostly simple, parametric changes in color and geometry. However, ...
  • Lake, Brenden M; Tenenbaum, Joshua B (Cognitive Science Society, Inc., 2010-08)
    Systems of concepts such as colors, animals, cities, and artifacts are richly structured, and people discover the structure of these domains throughout a lifetime of experience. Discovering structure can be formalized as ...
  • Lashkari, Danial; Vul, Edward; Kanwisher, Nancy; Golland, Polina (Elsevier, 2010-01)
    We present a method for discovering patterns of selectivity in fMRI data for experiments with multiple stimuli/tasks. We introduce a representation of the data as profiles of selectivity using linear regression estimates, ...
  • Reshetouski, Ilya; Manakov, Alkhazur; Bandhari, Ayush; Raskar, Ramesh; Seidel, Hans-Peter; Ihrke, Ivo; Bhandari, Ayush (Institute of Electrical and Electronics Engineers (IEEE), 2013-06)
    We investigate the problem of identifying the position of a viewer inside a room of planar mirrors with unknown geometry in conjunction with the room's shape parameters. We consider the observations to consist of angularly ...
  • Widhalm, Peter; Yang, Yingxiang; Ulm, Michael; Athavale, Shounak; Gonzalez, Marta C. (Springer US, 2015-03)
    Massive and passive data such as cell phone traces provide samples of the whereabouts and movements of individuals. These are a potential source of information for models of daily activities in a city. The main challenge ...
  • Jiang, Shan; Ferreira, Joseph, Jr.; Gonzalez, Marta C. (Association for Computing Machinery (ACM), 2012-08)
    Urban geographers, planners, and economists have long been studying urban spatial structure to understand the development of cities. Statistical and data mining techniques, as proposed in this paper, go a long way in ...
  • Simmons, Sean Kenneth; Peng, Jian; Bienkowska, Jadwiga R; Berger Leighton, Bonnie (Mary Ann Liebert, Inc., 2015-07)
    Biology is being inundated by noisy, high-dimensional data to an extent never before experienced. Dimensionality reduction techniques such as principal component analysis (PCA) are common approaches for dealing with this ...
  • Demory, Brice-Olivier; Seager, Sara (IOP Publishing, 2011-10)
    We report the discovery of planet Kepler-12b (KOI-20), which at 1.695 ± 0.030 R [subscript J] is among the handful of planets with super-inflated radii above 1.65 R [subscript J]. Orbiting its slightly evolved G0 host with ...
  • Ziarek, Joshua J.; Wagner, Gerhard; Wommack, Andrew; Tomaras, Jill M; Chileveru, Haritha reddy; Zhang, Yunfei; Nolan, Elizabeth Marie (American Chemical Society, 2014-09)
    We report the discovery of HD5-CD, an unprecedented C[subscript 2]-symmetric β-barrel-like covalent dimer of the cysteine-rich host-defense peptide human defensin 5 (HD5). Dimerization results from intermonomer disulfide ...
  • Lander, Eric S.; Costello, Maura; Pugh, Trevor J.; Fennell, Timothy; Stewart, Chip; Lichtenstein, Lee; Meldrim, James C.; Fostel, Jennifer L.; Friedrich, Dennis C.; Perrin, Danielle; Dionne, Danielle; Kim, Sharon; Gabriel, Stacey B.; Fisher, Sheila; Getz, Gad (Oxford University Press, 2013-01)
    As researchers begin probing deep coverage sequencing data for increasingly rare mutations and subclonal events, the fidelity of next generation sequencing (NGS) laboratory methods will become increasingly critical. Although ...
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