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Browsing MIT Open Access Articles by Title

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  • Robinson, James T.; Thorvaldsdóttir, Helga; Winckler, Wendy; Guttman, Mitchell; Lander, Eric S.; Getz, Gad; Mesirov, Jill P. (Nature Publishing Group, 2011-01)
    To the Editor: Rapid improvements in sequencing and array-based platforms are resulting in a flood of diverse genome-wide data, including data from exome and whole-genome sequencing, epigenetic surveys, expression profiling ...
  • Marchetti, Giovanni; Escuin, Sarah; van der Flier, Arjan; De Arcangelis, Adèle; Hynes, Richard O.; Georges-Labouesse, Elisabeth (Federation of European Neuroscience Societies and Blackwell Publishing Ltd, 2010-02)
    During cerebral cortex development, post-mitotic neurons interact with radial glial fibers and the extracellular environment to migrate away from the ventricular region and form a correct laminar structure. Integrin receptors ...
  • Shibue, Tsukasa; Weinberg, Robert A. (United States National Academy of Sciences, 2009-04)
    The development of metastases is an extended and inefficient process involving multiple steps. The last of these involves the growth of micrometastases into macroscopic tumors. We show here that intravenously injected, ...
  • Gupton, Stephanie L.; Gertler, Frank (Elsevier, 2010-05)
    Neurons establish their unique morphology by elaborating multiple neurites that subsequently form axons and dendrites. Neurite initiation entails significant surface area expansion, necessitating addition to the plasma ...
  • Gupton, Stephanie L.; Gertler, Frank (Elsevier B.V., 2010-05)
    Neurons establish their unique morphology by elaborating multiple neurites that subsequently form axons and dendrites. Neurite initiation entails significant surface area expansion, necessitating addition to the plasma ...
  • Ren, Ling; Yu, Xiangyao; Devadas, Srinivas; Fletcher, Christopher Wardlaw; Van Dijk, Marten (Institute of Electrical and Electronics Engineers (IEEE), 2013-09)
    Oblivious-RAMs (ORAM) are used to hide memory access patterns. Path ORAM has gained popularity due to its efficiency and simplicity. In this paper, we propose an efficient integrity verification layer for Path ORAM, which ...
  • Williams, Heidi L. (University of Chicago Press, 2013-02)
    Do intellectual property (IP) rights on existing technologies hinder subsequent innovation? Using newly-collected data on the sequencing of the human genome by the public Human Genome Project and the private rm Celera, ...
  • Acemoglu, Daron; Akcigit, Ufuk (Wiley Blackwell, 2011-12)
    To what extent and in what form should the intellectual property rights (IPR) of innovators be protected? Should a company with a large technology lead over its rivals receive the same IPR protection as a company with a ...
  • Redding, Josh; Geramifard, Alborz; Undurti, Aditya; Choi, Han-Lim; How, Jonathan P. (Institute of Electrical and Electronics Engineers, 2010-07)
    This paper presents an extension of existing cooperative control algorithms that have been developed for multi-UAV applications to utilize real-time observations and/or performance metric(s) in conjunction with learning ...
  • Geramifard, Alborz; Redding, Joshua; How, Jonathan P. (Springer-Verlag, 2013-03)
    Planning for multi-agent systems such as task assignment for teams of limited-fuel unmanned aerial vehicles (UAVs) is challenging due to uncertainties in the assumed models and the very large size of the planning space. ...
  • Klann, Jeffrey G.; Szolovits, Peter (BioMed Central Ltd, 2009-11)
    Background: Capturing accurate and machine-interpretable primary data from clinical encounters is a challenging task, yet critical to the integrity of the practice of medicine. We explore the intriguing possibility that ...
  • Graves, William S.; Kaertner, Franz X.; Moncton, David E.; Piot, Philippe (American Physical Society, 2012-06)
    A novel method of producing intense short wavelength radiation from relativistic electrons is described. The electrons are periodically bunched at the wavelength of interest enabling in-phase superradiant emission that is ...
  • Muller, Caroline; O'Gorman, Paul Ambrose; Back, Larissa E. (American Meteorological Society, 2011-06)
    A cloud-resolving model is used to investigate the effect of warming on high percentiles of precipitation (precipitation extremes) in the idealized setting of radiative-convective equilibrium. While this idealized setting ...
  • Howard, Newton; Cambria, Erik (Springer, 2013-06)
    As the gap between human and machine shrinks, it becomes increasingly important to develop computer systems that incorporate or enhance existing Situation Awareness. However, these tend to focus on raw quantitative parameters, ...
  • Bombin, Hector; Kargarian, M.; Martin-Delgado, M. A. (American Physical Society, 2009-08)
    We introduce a two-body quantum Hamiltonian model of spin 1/2 on a two-dimensional spatial lattice with exact topological degeneracy in all coupling regimes. There exists a gapped phase in which the low-energy sector ...
  • Wang, Chong; Todadri, Senthil (American Physical Society, 2014-05)
    Symmetry protected topological (SPT) phases are a minimal generalization of the concept of topological insulators to interacting systems. In this paper, we describe the classification and properties of such phases for ...
  • Tang, Evelyn May Yin; Wen, Xiao-Gang (American Physical Society, 2012-08)
    In free fermion systems with given symmetry and dimension, the possible topological phases are labeled by elements of only three types of Abelian groups, 0, Z[subscript 2], or Z. For example, noninteracting one-dimensional ...
  • Szolovits, Peter; Berners-Lee, Tim; Weitzner, Daniel J.; Schraefel, M. C.; André, Paul; White, Ryen; Tan, Desney; Consolvo, Sunny; Jacobs, Robert; Kohane, Isaac; La Dantec, Christopher A.; Mamykina, Lena; Marsden, Gary; Shneiderman, Ben (Association for Computing Machinery, 2009-04)
    While health records are increasingly stored electronically, we, as citizens, have little access to this data about ourselves. We are not used to thinking of these official records either as ours or as useful to us. We ...
  • Luhar, Mitul; Rominger, Jeffrey Tsaros; Nepf, Heidi (Springer-Verlag, 2008-07)
    This paper summarizes recent advances in vegetation hydrodynamics and uses the new concepts to explore not only how vegetation impacts flow and transport, but also how flow feedbacks can influence vegetation spatial ...
  • Coughlin, M.; Mitchison, T. J.; Chang, Paul (American Society for Cell Biology, 2009-09)
    Poly(ADP-ribose) (pADPr), made by PARP-5a/tankyrase-1, localizes to the poles of mitotic spindles and is required for bipolar spindle assembly, but its molecular function in the spindle is poorly understood. To investigate ...
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