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Browsing MIT Open Access Articles by Title

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  • Li, Aming; Broom, Mark; Du, Jinming; Wang, Long (American Physical Society, 2016-02)
    The evolution of populations is influenced by many factors, and the simple classical models have been developed in a number of important ways. Both population structure and multiplayer interactions have been shown to ...
  • Plunkett, Jevon; Doniger, Scott; Orabona, Guilherme; Morgan, Thomas; Haataja, Ritva; Hallman, Mikko; Puttonen, Hilkka; Menon, Ramkumar; Kuczynski, Edward; Norwitz, Errol; Snegovskikh, Victoria; Palotie, Aarno; Peltonen, Leena; Fellman, Vineta; DeFranco, Emily A.; Chaudhari, Bimal P.; McGregor, Tracy L.; McElroy, Jude J.; Oetjens, Matthew T.; Teramo, Kari; Borecki, Ingrid; Fay, Justin C.; Muglia, Louis J. (Public Library of Science, 2011-04)
    Coordination of fetal maturation with birth timing is essential for mammalian reproduction. In humans, preterm birth is a disorder of profound global health significance. The signals initiating parturition in humans have ...
  • Brennan, Thomas J.; Lo, Andrew W. (Public Library of Science, 2012-11)
    Background: Most economic theories are based on the premise that individuals maximize their own self-interest and correctly incorporate the structure of their environment into all decisions, thanks to human intelligence. ...
  • Weng, Jing-Ke (Wiley Blackwell, 2014-03)
    As sessile organisms, land plants have exploited their metabolic systems to produce a panoply of structurally and functionally diverse natural chemicals and polymers to adapt to challenging ecosystems. Many of these core ...
  • Thompson, Dawn A.; Roy, Sushmita; Chan, Michelle Mei Wah; Styczynsky, Mark P.; Pfiffner, Jenna; French, Courtney; Socha, Amanda; Thielke, Anne; Napolitano, Sara; Muller, Paul; Kellis, Manolis; Konieczka, Jay; Wapinski, Ilan; Regev, Aviv (eLife Sciences Publications, Ltd, 2013-06)
    Divergence in gene regulation can play a major role in evolution. Here, we used a phylogenetic framework to measure mRNA profiles in 15 yeast species from the phylum Ascomycota and reconstruct the evolution of their modular ...
  • Yang, Lei; Damkiaer, Soren; Molin, Soren; Jelsbak, Lars (National Academy of Sciences (U.S.), 2013-04)
    The genetic basis of bacterial adaptation to a natural environment has been investigated in a highly successful Pseudomonas aeruginosa lineage (DK2) that evolved within the airways of patients with cystic fibrosis (CF) for ...
  • Wu, Yi-Chieh; Rasmussen, Matthew D.; Kellis, Manolis (Oxford University Press (OUP), 2011-09)
    Although the possibility of gene evolution by domain rearrangements has long been appreciated, current methods for reconstructing and systematically analyzing gene family evolution are limited to events such as duplication, ...
  • Wu, Yi-Chieh; Rasmussen, Matthew D.; Kellis, Manolis (Oxford University Press (OUP), 2011-09)
    Although the possibility of gene evolution by domain rearrangements has long been appreciated, current methods for reconstructing and systematically analyzing gene family evolution are limited to events such as duplication, ...
  • George, Janet A.; Traverse, Karen L.; DeBaryshe, Gregory; Kelley, Kerry; Pardue, Mary-Lou (National Academy of Sciences (U.S.), 2010-11)
    The retrotransposons HeT-A, TART, and TAHRE, which maintain Drosophila telomeres, transpose specifically onto chromosome ends to form long arrays that extend the chromosome and compensate for terminal loss. Because they ...
  • Abbey, Darren A.; Issi, Luca; Guiducci, Candace; Martinez, Diego A; Delorey, Toni; Li, Bi yu; White, Theodore C; Cuomo, Christina; Rao, Reeta P; Berman, Judith; Thompson, Dawn A; Regev, Aviv; Ford, Christopher B.; Funt, Jason (eLife Sciences Publications, Ltd., 2015-02)
    Candida albicans is both a member of the healthy human microbiome and a major pathogen in immunocompromised individuals. Infections are typically treated with azole inhibitors of ergosterol biosynthesis often leading to ...
  • Franses, Joseph W.; Edelman, Elazer R. (American Association for Cancer Research, 2011-12)
    Although the roles of endothelial cells in cancer have primarily been considered to be related to tumor perfusion, the emerging appreciation of “angiocrine” regulation adds stromal regulatory capabilities to the expanding ...
  • Sommer, Ariel Tjodolv; Cheuk, Lawrence W.; Ku, Mark Jen-Hao; Bakr, Waseem S.; Zwierlein, Martin Wolfram (American Physical Society, 2012-01)
    We follow the evolution of fermion pairing in the dimensional crossover from three-dimensional to two-dimensional as a strongly interacting Fermi gas of [superscript 6]Li atoms becomes confined to a stack of two-dimensional ...
  • Li, Guohong; Luican-Mayer, Adina; Abanin, Dmitry A.; Levitov, Leonid; Andrei, Eva Y. (Nature Publishing Group, 2013-04)
    Two-dimensional electron systems in the presence of a magnetic field support topologically ordered states, in which the coexistence of an insulating bulk with conducting one-dimensional chiral edge states gives rise to the ...
  • Gruber, Jonathan; Levy, Helen (American Economic Association, 2009-09)
    How has the economic risk of health spending changed over time for U.S. households? We describe trends in aggregate health spending in the United States and how private insurance markets and public insurance programs have ...
  • Hynes, Richard O. (Rockefeller University Press, The, 2012-03)
    The modular domain structure of extracellular matrix (ECM) proteins and their genes has allowed extensive exon/domain shuffling during evolution to generate hundreds of ECM proteins. Many of these arose early during metazoan ...
  • Szulczewski, Michael Lawrence; Juanes, Ruben (Cambridge University Press, 2013-02)
    Gravity currents of miscible fluids in porous media are important to understand because they occur in important engineering projects, such as enhanced oil recovery and geologic CO[subscript 2] sequestration. These flows ...
  • Traverse, Karen L.; George, Janet A.; DeBaryshe, Gregory; Pardue, Mary-Lou (National Academy of Sciences (U.S.), 2010-03)
    The non-LTR retrotransposons forming Drosophila telomeres constitute a robust mechanism for telomere maintenance, one which has persisted since before separation of the extant Drosophila species. These elements in D. ...
  • Makaram, Prashanth; Joh, Jungwoo; del Alamo, Jesus A.; Palacios, Tomas; Thompson, Carl V. (American Institute of Physics (AIP), 2010-06)
    We have investigated the surface morphology of electrically stressed AlGaN/GaN high electron mobility transistors using atomic force microscopy and scanning electron microscopy after removing the gate metallization by ...
  • Jeltema, Tesla E.; Canizares, Claude R.; Bautz, Mark W.; Buote, David A. (IOP Publishing, 2005-05)
    Using Chandra archival data, we quantify the evolution of cluster morphology with redshift. Clusters form and grow through mergers with other clusters and groups, and the amount of substructure in clusters in the present ...
  • Waterhouse, Robert; Neafsey, Daniel E.; Christophides, George K.; Collins, Frank H.; Emrich, Scott J.; Fontaine, Michael C.; Gelbart, William; Hahn, Matthew W.; Howell, Paul I.; Kafatos, Fotis C.; Lawson, Daniel; Muskavitch, Marc A. T.; Williams, Louise J.; Besansky, Nora J. (Genetics Society of America, 2013-05)
    We report the imminent completion of a set of reference genome assemblies for 16 species of Anopheles mosquitoes. In addition to providing a generally useful resource for comparative genomic analyses, these genome sequences ...
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