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Browsing MIT Open Access Articles by Title

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  • A melting model for variably depleted and enriched lherzolite in the plagioclase and spinel stability fields 
    Till, Christy B.; Grove, Timothy L.; Krawczynski, Michael J. (American Geophysical Union (AGU), 2012-06)
    Here we develop a lherzolite melting model and explore the effects of variations in mantle composition, pressure, temperature, and H[subscript 2]O content on melt composition. New experiments and a compilation of experimental ...
  • Members of the miRNA-200 Family Regulate Olfactory Neurogenesis 
    Choi, Philip S.; Zakhary, Lisa; Choi, Wen-Yee; Caron, Sophie; Alvarez-Saavedra, Ezequiel; Miska, Eric A.; McManus, Mike; Harfe, Brian; Giraldez, Antonio J.; Horvitz, H. Robert; Schier, Alexander F.; Dulac, Catherine (Elsevier B.V., 2008-01)
    MicroRNAs (miRNAs) are highly expressed in vertebrate neural tissues, but the contribution of specific miRNAs to the development and function of different neuronal populations is still largely unknown. We report that miRNAs ...
  • Memory coherence in the age of multicores 
    Lis, Mieszko; Shim, Keun Sup; Cho, Myong Hyon; Devadas, Srinivas (Institute of Electrical and Electronics Engineers (IEEE), 2011-11)
    As we enter an era of exascale multicores, the question of efficiently supporting a shared memory model has become of paramount importance. On the one hand, programmers demand the convenience of coherent shared memory; on ...
  • Memory, plasticity, and sleep – a role for calcium permeable AMPA receptors? 
    Shepherd, Jason Dennis (Frontiers Research Foundation, 2012-04)
    Experience shapes and molds the brain throughout life.These changes in neuronal circuits are produced by a myriad of molecular and cellular processes. Simplistically, circuits are modified through changes in neurotransmitter ...
  • MemTable: An integrated system for capture and recall of shared histories in group workspaces 
    Hunter, Seth Edward; Maes, Patricia; Scott, Stacey; Kaufman, Henry (Association for Computing Machinery, 2011-05)
    This paper presents the design, implementation, and evaluation of an interactive tabletop system that supports co-located meeting capture and asynchronous search and review of past meetings. The goal of the project is to ...
  • Mena binds α5 integrin directly and modulates α5β1 function 
    Gupton, Stephanie L.; Riquelme, Daisy Noelia; Hughes-Alford, Shannon Kay; Tadros, Jenny; Rudina, Shireen S.; Hynes, Richard O.; Lauffenburger, Douglas A.; Gertler, Frank B. (Rockefeller University Press, The, 2012-08)
    Mena is an Ena/VASP family actin regulator with roles in cell migration, chemotaxis, cell–cell adhesion, tumor cell invasion, and metastasis. Although enriched in focal adhesions, Mena has no established function within ...
  • Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors 
    Roussos, Evanthia T.; Wang, Yarong; Wyckoff, Jeffrey B.; Sellers, Rani S.; Wang, Weigang; Li, Jiufeng; Pollard, Jeffrey W.; Gertler, Frank; Condeelis, John S. (BioMed Central Ltd., 2010-11)
    Introduction The actin binding protein Mammalian enabled (Mena), has been implicated in the metastatic progression of solid tumors in humans. Mena expression level in primary tumors is correlated with metastasis in ...
  • Menu Pricing and Learning 
    Bonatti, Alessandro (American Economic Association, 2011-08)
    We analyze the design of dynamic menus to sell experience goods. The quality of the product is initially unknown, and the total quantity sold in each period determines the amount of information in the market. We characterize ...
  • Merging Multiple-Partial-Depth Data Time Series Using Objective Empirical Orthogonal Function Fitting 
    Lin, Ying-Tsong; Newhall, Arthur E.; Duda, Timothy F.; Lermusiaux, Pierre F. J.; Haley, Patrick J. (Institute of Electrical and Electronics Engineers, 2010-10)
    In this paper, a method for merging partial overlapping time series of ocean profiles into a single time series of profiles using empirical orthogonal function (EOF) decomposition with the objective analysis is presented. ...
  • Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential 
    Drake, Adam; Chen, Qingfeng; Dong, Di; Leskov, Ilya; Fragoso, Maria F.; Li, Yan; Iliopoulou, Bettina P.; Hwang, William; Lodish, Harvey F.; Chen, Jianzhu (Mary Ann Liebert, 2010-12)
    Clinical and preclinical applications of human hematopoietic stem cells (HSCs) are often limited by scarcity of cells. Expanding human HSCs to increase their numbers while maintaining their stem cell properties has therefore ...
  • Meson-exchange currents and final-state interactions in quasielastic electron scattering at high momentum transfers 
    Amaro, J. E.; Barbaro, M. B.; Caballero, J. A.; Maieron, C.; Udias, J. M.; Donnelly, T. William (American Physical Society, 2010-01)
    The effects of meson-exchange currents (MEC) are computed for the one-particle one-hole transverse response function for finite nuclei at high momentum transfers q in the region of the quasi-elastic peak. A semirelativistic ...
  • Meson-exchange currents and quasielastic neutrino cross sections in the superscaling approximation model 
    Amaro, J. E.; Barbaro, M. B.; Caballero, J. A.; Donnelly, T. William (American Physical Society, 2012-04)
    We evaluate quasielastic double-differential antineutrino cross sections obtained in a phenomenological model based on the superscaling behavior of electron scattering data and estimate the contribution of the vector ...
  • Meson widths from string worldsheet instantons 
    Faulkner, Thomas; Liu, Hong (Elsevier, 2009-02)
    We show that open strings living on a D-brane which lies outside an AdS black hole We show that open strings living on a D-brane which lies outside an AdS black hole can tunnel into the black hole through worldsheet ...
  • Meso-Scale Modeling of Amorphous Metals by Shear Transformation Zone Dynamics 
    Homer, Eric R.; Schuh, Christopher A. (Elsevier, 2009-03)
    A new mesoscale modeling technique for the thermo-mechanical behavior of metallic glasses is proposed. The modeling framework considers the shear transformation zone (STZ) as the fundamental unit of deformation, and ...
  • Message Passing for Maximum Weight Independent Set 
    Sanghavi, Sujay; Shah, Devavrat; Willsky, Alan S. (2009-10)
    In this paper, we investigate the use of message-passing algorithms for the problem of finding the max-weight independent set (MWIS) in a graph. First, we study the performance of the classical loopy max-product belief ...
  • Message-passing for wireless scheduling: An experimental study 
    Giaccone, Paolo; Shah, Devavrat (Institute of Electrical and Electronics Engineers (IEEE), 2010-09)
    In the recent years, message-passing paradigm has emerged as a canonical algorithmic solution to solve networkwide problems by means of minimal local information exchange, across variety of disciplines. The primary purpose ...
  • Message quantization in belief propagation: Structural results in the low-rate regime 
    Willsky, Alan S.; Kreidl, Olivier Patrick (Institute of Electrical and Electronics Engineers, 2010-01)
    Motivated by distributed inference applications in unreliable communication networks, we adapt the popular (sum-product) belief propagation (BP) algorithm under the constraint of discrete-valued messages. We show that, in ...
  • Me[subscript 3](OMe)tBuXPhos: A Surrogate Ligand for Me[subscript 4]tBuXPhos in Palladium-Catalyzed C-N and C-O Bond-Forming Reactions 
    Ueda, Satoshi; Fors, Brett P.; Ali, Siraj Z.; Buchwald, Stephen Leffler (American Chemical Society (ACS), 2012-02)
    A new biarylphosphine ligand, Me[subscript 3](OMe)tBuXPhos (L3), was designed as a surrogate for Me[subscript 4]tBuXPhos (L1). The Me[subscript 3](OMe)tBuXPhos could be prepared in a chromatography-free manner from inexpensive ...
  • Metabolic cycling without cell division cycling in respiring yeast 
    Slavov, Nikolai G.; Macinskas, Joanna; Caudy, Amy; Botstein, David (National Academy of Sciences (U.S.), 2011-11)
    Despite rapid progress in characterizing the yeast metabolic cycle, its connection to the cell division cycle (CDC) has remained unclear. We discovered that a prototrophic batch culture of budding yeast, growing in a ...
  • Metabolic Factors Limiting Performance in Marathon Runners 
    Rapoport, Benjamin I. (Public Library of Science, 2010-10)
    Each year in the past three decades has seen hundreds of thousands of runners register to run a major marathon. Of those who attempt to race over the marathon distance of 26 miles and 385 yards (42.195 kilometers), more ...
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