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Browsing MIT Open Access Articles by Title

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  • Gilet, Tristan; Bush, John W. M. (American Institute of Physics (AIP), 2012-12)
    We present the results of an experimental investigation of fluid drops impacting an inclined rigid surface covered with a thin layer of high viscosity fluid. We deduce the conditions under which droplet bouncing, splitting, ...
  • Moon, Sangjun; Kim, Yun-Gon; Dong, Lingsheng; Lombardi, Michael; Haeggstrom, Edward; Jensen, Roderick V.; Hsiao, Li-Li; Demirci, Utkan (Public Library of Science, 2011-03)
    Technologies that rapidly isolate viable single cells from heterogeneous solutions have significantly contributed to the field of medical genomics. Challenges remain both to enable efficient extraction, isolation and ...
  • Renvoise, P.; Bush, John W. M.; Prakash, Manu; Quere, D. (European Physical Society by EDP Sciences, IOP Publishing and Società Italiana di Fisica, 2009-07)
    We present the results of a combined experimental and theoretical investigation of the motion of wetting droplets in tapered capillary tubes. We demonstrate that drops may move spontaneously towards the tapered end owing ...
  • Bush, John W. M.; Molacek, Jan (Cambridge University Press, 2013-06)
    We present the results of a combined experimental and theoretical investigation of millimetric droplets bouncing on a vertically vibrating fluid bath. We first characterize the system experimentally, deducing the dependence ...
  • Bush, John W. M.; Molacek, Jan (Cambridge University Press, 2013-06)
    We present the results of a combined experimental and theoretical investigation of droplets walking on a vertically vibrating fluid bath. Several walking states are reported, including pure resonant walkers that bounce ...
  • Rykaczewski, Konrad; Paxson, Adam T.; Staymates, Matthew; Walker, Marlon L.; Sun, Xiaoda; Anand, Sushant; Srinivasan, Siddarth; McKinley, Gareth H.; Chinn, Jeff; Scott, John Henry J.; Varanasi, Kripa K. (Nature Publishing Group, 2014-03)
    Compared to the significant body of work devoted to surface engineering for promoting dropwise condensation heat transfer of steam, much less attention has been dedicated to fluids with lower interfacial tension. A vast ...
  • Miljkovic, Nenad; Enright, Ryan; Alvarado, Jorge; Kwang, Kim; Rose, John (Taylor & Francis, 2014-03)
    In this review we cover recent developments in the area of surface- enhanced dropwise condensation against the background of earlier work. The development of fabrication techniques to create surface structures at the micro- ...
  • Rodal, Avital A.; Del Signore, Steven J.; Martin, Adam C (John Wiley & Sons, Inc., 2015-05)
    For the last 100 years, Drosophila melanogaster has been a powerhouse genetic system for understanding mechanisms of inheritance, development, and behavior in animals. In recent years, advances in imaging and genetic tools ...
  • Unhavaithaya, Yingdee; Park, Eugenia A.; Royzman, Irena; Orr-Weaver, Terry L. (Genetics Society of America, 2013-08)
    Nearly all cell division mutants in Drosophila were recovered in late larval/pupal lethal screens, with less than 10 embryonic lethal mutants identified, because larval development occurs without a requirement for cell ...
  • Park, Sang Mee; Park, Hae Ryoun; Littleton, J. Troy; Lee, Ji Hye (Korean Society for Brain and Neural Science (KAMJE), 2016-02)
    Copy number variations at multiple chromosomal loci, including 16p11.2, have recently been implicated in the pathogenesis of autism spectrum disorder (ASD), a neurodevelopmental disease that affects 1~3% of children ...
  • Hongaya, Cintia F.; Orr-Weaver, Terry L. (Proceedings of the National Academy of Sciences (PNAS), 2011-08)
    N⁶-methyladenosine is a nonediting RNA modification found in mRNA of all eukaryotes, from yeast to humans. Although the functional significance of N⁶-methyladenosine is unknown, the Inducer of MEiosis 4 (IME4) gene of ...
  • Hannan, Shabab B.; Stapper, Zeenna A.; Kern, Jeannine V.; Jahn, Thomas R.; Rasse, Tobias M.; Zhang, Yao (Frontiers Research Foundation, 2016-09)
    Mutations in the kinesin-3 family member KIF1A have been associated with hereditary spastic paraplegia (HSP), hereditary and sensory autonomic neuropathy type 2 (HSAN2) and non-syndromic intellectual disability (ID). Both ...
  • Krench, Megan A.; Cho, Richard W.; Littleton, J. Troy (Oxford University Press, 2016-05)
    Huntington disease-like 2 (HDL2) and Huntington disease (HD) are adult-onset neurodegenerative diseases characterized by movement disorders, psychiatric disturbances and cognitive decline. Brain tissue from HD and HDL2 ...
  • Heissler, Sarah M; Billington, Neil; Sellers, James R; Vasquez, Claudia G; Martin, Adam C (eLife Sciences Publications, Ltd., 2016-12)
    Non-muscle cell contractility is critical for tissues to adopt shape changes. Although, the non-muscle myosin II holoenzyme (myosin) is a molecular motor that powers contraction of actin cytoskeleton networks, recent studies ...
  • Pardue, Mary-Lou; DeBaryshe, P. G. (Landes Bioscience, 2008-05)
    In Drosophila, the role of telomerase is carried out by three specialized retrotransposable elements, HeT-A, TART, and TAHRE. Telomeres contain long tandem head-to-tail arrays of these elements. Within each array, the ...
  • Zaroug, M. A. H.; Eltahir, Elfatih A. B.; Giorgi, F. (Copernicus GmbH on behalf of the European Geosciences Union, 2014-03)
    The Blue Nile originates from Lake Tana in the Ethiopian Highlands and contributes about 60–69% of the main Nile discharge. Previous studies investigated the relationship of sea surface temperature (SST) in the Pacific ...
  • Famm, Kristoffer; Litt, Brian; Tracey, Kevin J.; Boyden, Edward Stuart; Slaoui, Moncef (Nature Publishing Group, 2013-04)
    Imagine a day when electrical impulses are a mainstay of medical treatment. Your clinician will administer electroceuticals that target individual nerve fibres or specific brain circuits to treat an array of conditions. ...
  • Molavian, Hamid R.; Goldman, Aaron; Phipps, Colin J.; Kohandel, Mohammad; Wouters, Bradly G.; Sengupta, Shiladitya; Sivaloganathan, Sivabal (Springer Nature, 2016-06)
    Pharmacological concentrations of small molecule natural products, such as ascorbic acid, have exhibited distinct cell killing outcomes between cancer and normal cells whereby cancer cells undergo apoptosis or necrosis ...
  • Maire, Cecile L; Murakami, Mark A; Knoff, David S; Liu, Huiyun; Haidar, Samer; Idbaih, Ahmed; Weinstock, David M; Ligon, Keith L; Stevens, Mark M.; Chou, Shijie Nigel; Kikuchi, Yuki; Kimmerling, Robert John; Calistri, Nicholas L; Cermak, Nathan; Olcum, Selim A.; Cordero, Nicolas; Wen, Patrick; Manalis, Scott R (Nature Publishing Group, 2016-10)
    Assays that can determine the response of tumor cells to cancer therapeutics could greatly aid the selection of drug regimens for individual patients. However, the utility of current functional assays is limited, and ...
  • Mendoza, Hiroshi A.; Ashall, Daniel T.; Yin, Allen S.; Baldo, Marc A.; Bahlke, Matthias Erhard (Wiley Blackwell, 2012-09)
    To address the incompatibility of organic semiconductors with traditional photolithography, an inert, frozen CO[subscript 2] resist is demonstrated that forms an in situ shadow mask. Contact with a room-temperature ...
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