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Browsing MIT Open Access Articles by Title

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  • Seneff, Stephanie; Lauritzen, Ann; Davidson, Robert; Lentz-Marino, Laurie (MDPI AG, 2012-12)
    Theoretical inferences, based on biophysical, biochemical, and biosemiotic considerations, are related here to the pathogenesis of cardiovascular disease, diabetes, and other degenerative conditions. We suggest that the ...
  • Kitamura, Takashi; Pignatelli di Spinazzola, Mich; Suh, Junghyup; Kohara, Keigo; Tonegawa, Susumu; Yoshiki, Atsushi; Abe, Kuniya (American Association for the Advancement of Science (AAAS), 2014-01)
    Episodic memory requires associations of temporally discontiguous events. In the entorhinal-hippocampal network, temporal associations are driven by a direct pathway from layer III of the medial entorhinal cortex (MECIII) ...
  • Papas, Klearchos K.; Suszynski, Thomas M.; Colton, Clark K. (Lippincott Williams & Wilkins, 2009-12)
    Purpose of review: There is a critical need for meaningful viability and potency assays that characterize islet preparations for release prior to clinical islet cell transplantation (ICT). Development, testing, and ...
  • Lohith, Talakad G; Osterweil, Emily K; Fujita, Masahiro; Jenko, Kimberly J; Bear, Mark F; Innis, Robert B (BioMed Central Ltd, 2013-05)
    Abstract Background: Fragile X syndrome (FXS) is a common inherited form of intellectual disability caused by loss of function of the fragile X mental retardation protein. Recent animal ...
  • Johnson, Simon; Larson, William; Papageorgiou, Chris; Subramanian, Arvind (Elsevier B.V., 2013-03)
    This paper sheds light on two problems in the Penn World Table (PWT) GDP estimates. First, we show that these estimates vary substantially across different versions of the PWT despite being derived from very similar ...
  • Park, Daniel Kyu; Singh, Rohit; Baym, Michael Hartmann; Liao, Chung-Shou; Berger, Bonnie (Oxford University Press, 2011-01)
    We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorhabditis elegans, Mus musculus and Homo ...
  • Hou, Han Wei; Warkiani, Majid Ebrahimi; Khoo, Bee Luan; Li, Zi Rui; Soo, Ross A.; Tan, Daniel Shao-Weng; Lim, Wan-Teck; Han, Jongyoon; Bhagat, Ali Asgar S.; Lim, Chwee Teck (Nature Publishing Group, 2013-02)
    Presence and frequency of rare circulating tumor cells (CTCs) in bloodstreams of cancer patients are pivotal to early cancer detection and treatment monitoring. Here, we use a spiral microchannel with inherent centrifugal ...
  • Marinescu, Smaranda C.; Levine, Daniel S.; Zhao, Yu; Schrock, Richard Royce; Hoveyda, Amir H. (American Chemical Society, 2011-08)
    Monoaryloxide–pyrrolide (MAP) complexes of molybdenum were employed for the selective ethenolysis of 1,2-disubstituted Z olefins in the presence of the corresponding E olefins. Reactions were performed in the presence of ...
  • Wang, Y.; Phon, T. H.; Pfeifer, B.; Ajikumar, Parayil Kumaran; Xiao, Wen-Hai; Tyo, Keith E. J.; Simeon, Fritz; Tyo, Keith E. J.; Leonard, Effendi; Mucha, Oliver; Stephanopoulos, Gregory (American Association for the Advancement of Science (AAAS), 2010-09)
    Taxol (paclitaxel) is a potent anticancer drug first isolated from the Taxus brevifolia Pacific yew tree. Currently, cost-efficient production of Taxol and its analogs remains limited. Here, we report a multivariate-modular ...
  • Liao, Chung-Shou; Lu, Kanghao; Baym, Michael Hartmann; Singh, Rohit (Oxford University Press, 2009-06)
    Motivation: With the increasing availability of large protein–protein interaction networks, the question of protein network alignment is becoming central to systems biology. Network alignment is further delineated into two ...
  • Serbyn, Maksym; Lee, Patrick A. (American Physical Society, 2011-01)
    We investigate the isotope effect on the London penetration depth of a superconductor which measures nS/m* [n subscript s / m superscript asterisk], the ratio of superfluid density to effective mass. We use a simplified ...
  • Wu, Jingfeng; Rember, Robert; Jin, Meibin; Boyle, Edward A.; Flegal, A. Russell (Elsevier, 2010-08)
    The absence of accurate measurements of lead (Pb) isotopic composition in the pristine North Pacific abyssal water has made it difficult to assess the relative importance of what are believed to be the two major Pb sources: ...
  • Mulligan, Michael; Nayak, Chetan; Kachru, Shamit (American Physical Society, 2010-08)
    We study an Abelian gauge theory in 2+1 dimensions which has surprising theoretical and phenomenological features. The theory has a vanishing coefficient for the square of the electric field ei2, characteristic of a quantum ...
  • Ellison, Glenn (John Wiley & Sons, Inc., 2011-03)
    Over the past decade, there has been a decline in the fraction of papers in top economics journals written by economists from the highest-ranked economics departments. This paper documents this fact and uses additional ...
  • Malani, Shreya; Prasanna, G.N. Srinivasa; del Alamo, Jesus A.; Hardison, James L.; Moudgalya, Kannan; Chopella, Venkatesh (Institute of Electrical and Electronics Engineers (IEEE), 2012-07)
    An Online Lab is a multi-university shared laboratory environment, where students can exercise their knowledge as they would do in a physical lab. The idea is to have maximum resource utilization and collaboration between ...
  • Medard, Muriel; Chang, Christopher S.; Ho, Tracey; Effros, Michelle; Leong, Ben (Institute of Electrical and Electronics Engineers, 2010-06)
    In this paper we consider a linear optimization approach for studying download finish times in peer-to-peer networks that allow but do not require coding. We demonstrate that using the network coding framework simplifies ...
  • Johnson, Steven G.; Levin, Michael (American Association of Physics Teachers (AAPT), 2011-08)
    We give an example of a geometry in which the electrostatic force between a point charge and a neutral metallic object is repulsive. The example consists of a point charge centered above a thin metallic hemisphere, positioned ...
  • Lockwood, Ronald B.; Cooley, T.; Jacobson, J.; Manolakis, Dimitris G. (The International Society for Optical Engineering, 2009-04)
    A large number of hyperspectral detection algorithms have been developed and used over the last two decades. Some algorithms are based on highly sophisticated mathematical models and methods; others are derived using ...
  • Allcott, Hunt Volney; Greenstone, Michael (American Economic Association, 2012-01)
    Many analysts of the energy industry have long believed that energy efficiency offers an enormous "win-win" opportunity: through aggressive energy conservation policies, we can both save money and reduce negative externalities ...
  • Acemoglu, Daron; Robinson, James A. (Walter de Gruyter, 2012-03)
    Societies are molded by their institutions that determine both their levels of prosperity and how that prosperity is distributed within society. For most of its history the U.S. has had economic institutions which have ...
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