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Browsing MIT Open Access Articles by Title

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  • Krueger, Andrew T.; Imperiali, Barbara (Wiley Blackwell, 2013-04)
    Fluorescence spectroscopy is a powerful tool for probing complex biological processes. The ubiquity of peptide–protein and protein–protein interactions in these processes has made them important targets for fluorescence ...
  • Ahmed, Eilaf; Hammond, Paula T.; Morton, Stephen Winford; Swager, Timothy Manning (Wiley Blackwell, 2013-06)
    Highly fluorescent multiblock conjugated polymer nanoparticles with folic acid surface ligands are highly effective for bioimaging and in vivo tumor targeting. The targeted nanoparticles were preferentially localized in ...
  • Chauhan, Vikash P.; Popovic, Zoran; Chen, Ou; Cui, Jian; Fukumura, Dai; Bawendi, Moungi G.; Jain, Rakesh K. (Wiley Blackwell (John Wiley & Sons), 2011-10)
    Shape dependent: Fluorescent quantum-dot-based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios were developed for real-time in vivo tumor imaging. The nanorods ...
  • Seto, Jennifer E.; Polat, Baris E.; VanVeller, Brett; Langer, Robert; Blankschtein, Daniel; Lopez, Renata F. V. (Elsevier, 2011-10)
    Chemical penetration enhancers are often used to enhance transdermal drug delivery. However, the fundamental mechanisms that govern the interactions between penetration enhancers and skin are not fully understood. Therefore, ...
  • Uttamapinant, Chayasith; White, Katherine A.; Baruah, Hemanta; Thompson, Samuel; Fernandez-Suarez, Marta; Puthenveetil, Sujiet; Ting, Alice Y. (National Academy of Sciences (U.S.), 2010-06)
    Biological microscopy would benefit from smaller alternatives to green fluorescent protein for imaging specific proteins in living cells. Here we introduce PRIME (PRobe Incorporation Mediated by Enzymes), a method for ...
  • Lim, Jeewoo; Swager, Timothy Manning (Wiley-VCH Verlag GmbH & Co. KGaA, 2010-09)
    It's just a phase: A highly fluorinated compound with a rigid three-dimensional architecture was synthesized as a monomer for poly(p-phenyleneethynylene)s (PPEs). Fluorous biphase reactions were applied for the synthesis ...
  • Iniguez, Sergio D.; Alcantara, Lyonna F.; Warren, Brandon L.; Riggs, Lace M.; Parise, Eric M.; Vialou, Vincent; Wright, Katherine N.; Dayrit, Genesis; Nieto, Steven J.; Wilkinson, Matthew B.; Lobo, Mary Kay; Neve, Rachael L.; Nestle, Eric J.; Bolaños-Guzmán, Carlos A. (Society for Neuroscience, 2014-01)
    The mechanisms underlying the enduring neurobiological consequences of antidepressant exposure during adolescence are poorly understood. Here, we assessed the long-term effects of exposure to fluoxetine (FLX), a selective ...
  • Kerman, Andrew J. (2013-10)
    It has long been thought that macroscopic phase coherence breaks down in effectively lower-dimensional superconducting systems even at zero temperature due to enhanced topological quantum phase fluctuations. In ...
  • Görler, T.; Told, D.; Jenko, F.; Holland, C.; Rhodes, T. L.; White, Anne E. (American Institute of Physics (AIP), 2014-12)
    Previous nonlinear gyrokinetic simulations of specific DIII-D L-mode cases have been found to significantly underpredict the ion heat transport and associated density and temperature fluctuation levels by up to almost one ...
  • Yoshihara, Fumiki; Nakamura, Yasunobu; Yan, Fei; Gustavsson, Simon; Bylander, Jonas; Oliver, William D.; Tsai, Jaw-Shen (American Physical Society, 2014-01)
    We infer the high-frequency flux noise spectrum in a superconducting flux qubit by studying the decay of Rabi oscillations under strong driving conditions. The large anharmonicity of the qubit and its strong inductive ...
  • Saxe, Rebecca R.; Young, Liane (MIT Press, 2009-04)
    Human moral judgment depends critically on “theory of mind,” the capacity to represent the mental states of agents. Recent studies suggest that the right TPJ (RTPJ) and, to lesser extent, the left TPJ (LTPJ), the precuneus ...
  • Ghosh, Satrajit; Guenther, Frank H.; Perkell, Joseph S.; Cai, Shanqing (Society for Neuroscience, 2011-11)
    Within the human motor repertoire, speech production has a uniquely high level of spatiotemporal complexity. The production of running speech comprises the traversing of spatial positions with precisely coordinated articulator ...
  • Li, Junlun; Kuleli, Huseyin Sadi; Zhang, Haijiang; Toksoz, M. Nafi (Society of Exploration Geophysicists, 2011-12)
    A new, relatively high frequency, full waveform matching method was used to study the focal mechanisms of small, local earthquakes induced in an oil field, which are monitored by a sparse near-surface network and a deep ...
  • Bautz, Marshall W.; Foster, Richard F.; Murray, S. S.; WFXT Team (Institute of Electrical and Electronics Engineers, 2010-06)
    The three X-ray imaging focal planes of the Wide-Field X-ray Telescope (WFXT) Mission will each have a field of view up to 1 degree square, pixel pitch smaller than 1 arcsec, excellent X-ray detection efficiency and spectral ...
  • Yao, Lining; DeVincenzi, Anthony; Pereira, Anna; Ishii, Hiroshi (Association for Computing Machinery (ACM), 2013-07)
    We introduce FocalSpace, a video conferencing system that dynamically recognizes relevant activities and objects through depth sensing and hybrid tracking of multimodal cues, such as voice, gesture, and proximity to surfaces. ...
  • Maimone, Andrew; Wetzstein, Gordon; Hirsch, Matthew Waggener; Lanman, Douglas R.; Raskar, Ramesh; Fuchs, Henry (Association for Computing Machinery, 2013-09)
    We present a glasses-free 3D display design with the potential to provide viewers with nearly correct accommodative depth cues, as well as motion parallax and binocular cues. Building on multilayer attenuator and directional ...
  • Dooley, William C.; Vargas, Hernan I.; Fenn, Alan J.; Tomaselli, Mary Beth; Harness, Jay K. (Springer New York, 2009-12)
    Background: Preoperative focused microwave thermotherapy (FMT) is a promising method for targeted treatment of breast cancer cells. Results of four multi-institutional clinical studies of preoperative FMT for treating ...
  • Leitenstorfer, Alfred; Nelson, Keith Adam; Reimann, Klaus; Tanaka, Koichiro (Institute of Physics Publishing and Deutsche Physikalische Gesellschaft, 2014-04)
    Resulting from the availability of improved sources, research in the terahertz (THz) spectral range has increased dramatically over the last decade, leading essentially to the disappearance of the so-called 'THz gap'. While ...
  • Lecuyer, Sigolene; Stocker, Roman; Rusconi, Roberto (IOP Publishing, 2015-03)
    Bacteria are the smallest and most abundant form of life. They have traditionally been considered as primarily planktonic organisms, swimming or floating in a liquid medium, and this view has shaped many of the approaches ...
  • Li, Lan; Zhang, Ping; Wang, Wei-Ming; Lin, Hongtao; Zerdoum, Aidan B.; Geiger, Sarah J.; Liu, Yangchen; Xiao, Nicholas; Zou, Yi; Ogbuu, Okechukwu; Du, Qingyang; Jia, Xinqiao; Li, Jingjing; Hu, Juejun (Nature Publishing Group, 2015-09)
    Integrated photonics provides a miniaturized and potentially implantable platform to manipulate and enhance the interactions between light and biological molecules or tissues in in-vitro and in-vivo settings, and is thus ...
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