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Browsing MIT Open Access Articles by Title

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  • Deisboeck, Thomas S. (European Molecular Biology Organization / Nature Publishing, 2009-03)
    According to the SEER Cancer Statistics Review, between 1975 and 2005, the deaths from heart disease in the United States declined from 37.8 to 26.6%, whereas over the same period those from cancer increased from 19.2 ...
  • Hidalgo-Sotelo, Barbara Irene; Oliva, Aude (Cognitive Science Society, 2010-08)
    What is the role of an individual’s past experience in guiding gaze in familiar environments? Contemporary models of search guidance suggest high level scene context is a strong predictor of where observers search in ...
  • Biderman, Assaf; Pereira, Francisco; Alves, Ana; Oliveirinha, Jo˜ao (Institute of Electrical and Electronics Engineers, 2009-09)
    We present a methodology for extraction of semantic indexes related to a given geo-referenced place. These lists of words correspond to the concepts that should be semantically related to that place, according to a number ...
  • Siegel, Mikey; Breazeal, Cynthia Lynn; Norton, Michael I. (Institute of Electrical and Electronics Engineers / Robotics Society of Japan, 2009-10)
    Persuasive Robotics is the study of persuasion as it applies to human-robot interaction (HRI). Persuasion can be generally defined as an attempt to change another’s beliefs or behavior. The act of influencing others is ...
  • Qiao, Wenlian; Quon, Gerald; Csaszar, Elizabeth; Yu, Mei; Morris, Quaid; Zandstra, Peter W. (Public Library of Science, 2012-12)
    The cellular composition of heterogeneous samples can be predicted using an expression deconvolution algorithm to decompose their gene expression profiles based on pre-defined, reference gene expression profiles of the ...
  • Chen, Mark; Bartlett, Alice I.; Nerenberg, Paul S.; Friel, Claire T.; Hackenberger, Christian P. R.; Stultz, Collin M.; Radford, Sheena E.; Imperiali, Barbara (National Academy of Sciences, 2010-12)
    N-linked glycosylation modulates protein folding and stability through a variety of mechanisms. As such there is considerable interest in the development of general rules to predict the structural consequences of site-specific ...
  • Chi, Pei-Yu; Lo, Jin-Ling; Chu, Hao-Hua; Wang, Hsin-Yen; Chou, Seng-Cho T. (Institute of Electrical and Electronics Engineers, 2009-07)
    Embedding digital technology into playful activity can make play-based occupational therapy more effective. This study proposes two play-based activities to improve children's eating and tooth-brushing behavior.
  • Resch, Bernd; Mittlboeck, Manfred; Lippautz, Michael (Molecular Diversity Preservation International. (MDPI), 2010-12)
    Geo-sensor networks have traditionally been built up in closed monolithic systems, thus limiting trans-domain usage of real-time measurements. This paper presents the technical infrastructure of a standardised embedded ...
  • Madan, Anmol Prem Prakash; Farrahi, Katayoun; Gatica-Perez, Daniel; Pentland, Alex Paul (Springer, 2011-06)
    Exposure and adoption of opinions in social networks are important questions in education, business, and government. We de- scribe a novel application of pervasive computing based on using mobile phone sensors to measure ...
  • Cotsapas, Chris; Voight, Benjamin F.; Lage, Kasper; Neale, Benjamin M.; Wallace, Chris; Abecasis, Gonçalo R.; Barrett, Jeffrey C.; Behrens, Timothy; Cho, Judy; Jager, Philip L. De; Elder, James T.; Graham, Robert R.; Gregersen, Peter; Klareskog, Lars; Siminovitch, Katherine A.; Heel, David A. van; Wijmenga, Cisca; Worthington, Jane; Todd, John A.; Hafler, David A.; Rich, Stephen S.; Daly, Mark J.; Rossin, Elizabeth (Public Library of Science, 2011-08)
    Genome-wide association (GWA) studies have identified numerous, replicable, genetic associations between common single nucleotide polymorphisms (SNPs) and risk of common autoimmune and inflammatory (immune-mediated) diseases, ...
  • Pham, Hubert; Paluska, Justin Mazzola (Institute of Electrical and Electronics Engineers, 2010-03)
    Debugging pervasive applications is difficult due to their distributed, asynchronous, and dynamic nature. To help ease the debugging process, we propose PerViz, a developer-targeted tool that enhances system visibility ...
  • Ansel, Jason Andrew; Chan, Cy; Wong, Yee Lok; Olszewski, Marek Krystyn; Zhao, Qin; Edelman, Alan; Amarasinghe, Saman P. (Association for Computing Machinery, 2009-06)
    It is often impossible to obtain a one-size-fits-all solution for high performance algorithms when considering different choices for data distributions, parallelism, transformations, and blocking. The best solution to these ...
  • Caffrey, Daniel R; Dana, Paul H; Mathur, Vidhya; Ocano, Marco; Hong, Eun-Jong; Wang, Yaoyu E; Somaroo, Shyamal; Caffrey, Brian E; Potluri, Shobha; Huang, Enoch S (BioMed Central Ltd, 2007-10)
    Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to identify trends that relate to function. ...
  • North, Trista E.; Vedder, Lea M.; Lord, Allegra M.; Wishnok, John S.; Tannenbaum, Steven Robert; Zon, Leonard I.; Goessling, Wolfram; Badu, I. Ramesh (National Academy of Sciences (U.S.), 2010-10)
    Acetaminophen (APAP) toxicity is the most common drug-induced cause of acute liver failure in the United States. The only available treatment, N-acetylcysteine (NAC), has a limited time window of efficacy, indicating a ...
  • Thompson, Luke Richard; Zeng, Qinglu; Kelly, Libusha; Huang, Katherine H.; Singer, Alexander U.; Stubbe, JoAnne; Chisholm, Sallie (Penny) (National Academy of Sciences (U.S.), 2011-09)
    Cyanophages infecting the marine cyanobacteria Prochlorococcus and Synechococcus encode and express genes for the photosynthetic light reactions. Sequenced cyanophage genomes lack Calvin cycle genes, however, suggesting ...
  • Rädler, Joachim; Horton, Margaret R.; Gast, Alice Petry (Elsevier, 2006-10)
    The membrane binding and model lipid raft interaction of synthetic peptides derived from the caveolin scaffolding domain (CSD) of the protein caveolin-1 have been investigated. CSD peptides bind preferentially to ...
  • Shapiro, Jeffrey H.; Le Gouet, Julien; Venkatraman, Dheera; Wong, Franco N. C. (Institute of Electrical and Electronics Engineers, 2009-04)
    We demonstrate a new type of optical coherence tomography using only classical resources to achieve results that are typically associated with quantum-enhanced metrology: factor-of-two axial resolution enhancement and ...
  • Edlund, Eric Matthias; Porkolab, Miklos; Kramer, G. J.; Lin, Liang; Lin, Yijun; Wukitch, Stephen James (American Institute of Physics, 2009-03)
    Reversed shear Alfvén eigenmodes (RSAEs) have been observed with the phase contrast imaging diagnostic and Mirnov coils during the sawtooth cycle in Alcator C-mod [M. Greenwald et al., Nucl. Fusion 45, S109 (2005)] plasmas ...
  • Siegel, Markus; Warden, Melissa R.; Miller, Earl K. (National Academy of Sciences (U.S.), 2009-12)
    The ability to hold multiple objects in memory is fundamental to intelligent behavior, but its neural basis remains poorly understood. It has been suggested that multiple items may be held in memory by oscillatory activity ...
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