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Browsing MIT Open Access Articles by Title

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  • Schwartz, Ernst; Kasprian, Gregor; Gruber, Gerlinde M.; Prayer, Daniela; Langs, Georg; Jakab, András; Schöpf, Veronika (Frontiers Research Foundation, 2014-10)
    The functional connectivity architecture of the adult human brain enables complex cognitive processes, and exhibits a remarkably complex structure shared across individuals. We are only beginning to understand its heterogeneous ...
  • Chou, Song; Flygare, Johan; Lodish, Harvey F. (Elsevier, 2013-02)
    We have developed a coculture system that establishes DLK[superscript +] fetal hepatic progenitors as the authentic supportive cells for expansion of hematopoietic stem (HSCs) and progenitor cells. In 1-week cultures ...
  • Chou, Song; Lodish, Harvey F. (National Academy of Sciences, 2010-03)
    Previously we showed that the ~2% of fetal liver cells reactive with an anti-CD3ε monoclonal antibody support ex vivo expansion of both fetal liver and bone marrow hematopoietic stem cells (HSCs); these cells express two ...
  • Young, David Y.; Young, John D.; Martel, Jan; Wu, Cheng-Yeu (Public Library of Science, 2009-11)
    Serum-derived granulations and purported nanobacteria (NB) are pleomorphic apatite structures shown to resemble calcium granules widely distributed in nature. They appear to be assembled through a dual inhibitory-seeding ...
  • Surmeier, D. James; Graybiel, Ann M. (Elsevier, 2012-07)
    In this issue of Neuron, Threlfell et al. (2012) report that synchronous activation of cholinergic interneurons evokes striatal dopamine release by activating presynaptic nicotinic acetylcholine receptors. These findings ...
  • Vuletic, Vladan; Peyronel, Thibault Michel Max; Lukin, M. D.; Zibrov, A. S.; Hafezi, Mohammad; Balic, Vlatko; Hofferberth, Sebastian; Bajcsy, Michal (The International Society for Optical Engineering, 2009-02)
    Cold atoms confined inside a hollow-core photonic-crystal fiber with core diameters of a few photon wavelengths are a promising medium for studying nonlinear optical interactions at extremely low light levels. The high ...
  • Bajcsy, Michal; Hofferberth, Sebastian; Balic, Vlatko; Peyronel, Thibault Michel Max; Zibrov, A. S.; Hafezi, Mohammad; Vuletic, Vladan; Lukin, M. D. (Society of Photo-Optical Instrumentation Engineers, 2009-02)
    Cold atoms confined inside a hollow-core photonic-crystal fiber with core diameters of a few photon wavelengths are a promising medium for studying nonlinear optical interactions at extremely low light levels. The high ...
  • Ku, Mark Jen-Hao; Sommer, Ariel Tjodolv; Cheuk, Lawrence W.; Zwierlein, Martin Wolfram; Houcke, K. Van; Werner, F.; Kozik, E.; Prokofev, N.; Svistunov, B.; Schirotzek, A. (Nature Publishing Group, 2012-03)
    Precise understanding of strongly interacting fermions, from electrons in modern materials to nuclear matter, presents a major goal in modern physics. However, the theoretical description of interacting Fermi systems is ...
  • Raj, Bhiksha; Turicchia, Lorenzo; Schmidt-Nielsen, Bent; Sarpeshkar, Rahul (Hindawi Publishing Corporation, 2007-06)
    We describe an FFT-based companding algorithm for preprocessing speech before recognition. The algorithm mimics tone-to-tone suppression and masking in the auditory system to improve automatic speech recognition performance ...
  • Chen, Pei-Yu; Qin, Lingfeng; Barnes, Carmen; Charisse, Klaus; Yi, Tai; Zhang, Xinbo; Ali, Rahmat; Medina, Pedro P.; Yu, Jun; Slack, Frank J.; Kotelianski, Victor E.; Wang, Fen; Tellides, George; Simons, Michael; Anderson, Daniel Griffith (Elsevier, 2012-11)
    Maintenance of normal endothelial function is critical to various aspects of blood vessel function, but its regulation is poorly understood. In this study, we show that disruption of baseline fibroblast growth factor (FGF) ...
  • Delaware, Benjamin James; Pit-Claudel, Clement F.; Gross, Jason S.; Chlipala, Adam (Association for Computing Machinery, 2015-01)
    We present Fiat, a library for the Coq proof assistant supporting refinement of declarative specifications into efficient functional programs with a high degree of automation. Each refinement process leaves a proof trail, ...
  • Mekkaoui, Choukri; Huang, Shuning; Chen, Howard H.; Dai, Guangping; Reese, Timothy G; Kostis, William J; Thiagalingam, Aravinda; Maurovich-Horvat, Pal; Ruskin, Jeremy N; Hoffmann, Udo; Jackowski, Marcel P; Sosnovik, David (BioMed Central Ltd, 2012-10)
    Background: The study of myofiber reorganization in the remote zone after myocardial infarction has been performed in 2D. Microstructural reorganization in remodeled hearts, however, can only be fully appreciated by ...
  • Tsai, Tsung-Han; Zhou, Chao; Fujimoto, James G. (Institute of Electrical and Electronics Engineers (IEEE), 2010-07)
    An improved design for fiber bundle fluorescence endomicroscopy is demonstrated. Scanned illumination and detection using coherent fiber bundles with 30,000 elements with 3 μm resolution enables high speed imaging with ...
  • Hu, Xiaolong; Zhong, Tian; White, James E.; Dauler, Eric A.; Najafi, Faraz; Herder, Charles Henry; Wong, Franco N. C.; Berggren, Karl K. (Optical Society of America, 2009-11)
    We developed a fiber-coupled superconducting nanowire single-photon detector system in a close-cycled cryocooler and achieved 24% and 22% system detection efficiencies at wavelengths of 1550 and 1315 nm, respectively. The ...
  • Orf, Nicholas D.; Shapira, Ofer; Sorin, Fabien; Danto, Sylvain; Baldo, Marc A.; Joannopoulos, John D.; Fink, Yoel (National Academy of Sciences (U.S.), 2011-03)
    The synthesis of a high-melting temperature semiconductor in a low-temperature fiber drawing process is demonstrated, substantially expanding the set of materials that can be incorporated into fibers. Reagents in the solid ...
  • Ng, Chee Ping; Zhuang, Yuhang; Lin, Alex Wei Haw; Teo, Jeremy Choon Meng (Hindawi Publishing Corporation, 2013)
    A bioartificial renal proximal tubule is successfully engineered as a first step towards a bioartificial kidney for improved renal substitution therapy. To engineer the tubule, a tunable hollow fiber membrane with an ...
  • Xu, Kun; Tian, Xuejun; Movassaghi, Mohammad; Kuperwasser, Charlotte; Oh, Sun Y.; Naber, Stephen P.; Buchsbaum, Rachel J. (BioMed Central, 2016-01)
    Background The tumor microenvironment has complex effects in cancer pathophysiology that are not fully understood. Most cancer therapies are directed against malignant cells specifically, leaving pro-malignant signals ...
  • Yu, Hanry; So, Peter T. C.; Rajapakse, Jagath; Chen, Chien Shing; Tang, Hui-Huan; Chang, Shi; Xiao, Guangfa; Raja, Anju Mythreyi; Wei, Chiang Li; Wee, Aileen; Cheng, Chee Leong; Chia, Ser-Mien; Kang, Chiang Huen; Xu, Shuoyu; Tan, Nancy; Tai, Dean C. S. (Society of Photo-Optical Instrumentation Engineers, 2009-07)
    We develop a standardized, fully automated, quantification system for liver fibrosis assessment using second harmonic generation microscopy and a morphology-based quantification algorithm. Liver fibrosis is associated with ...
  • Taylor, Frank E. (Elsevier, 2014-09)
    Measurements of fiducial and differential cross sections of Higgs boson production in the H→ZZ*→4ℓ decay channel are presented. The cross sections are determined within a fiducial phase space and corrected for detection ...
  • Pollock, Nira R.; McGray, Sarah; Colby, Donn J.; Noubary, Farzad; Nguyen, Huyen; Nguyen, The Anh; Khormaee, Sariah; Jain, Sidhartha; Hawkins, Kenneth; Kumar, Shailendra; Rolland, Jason P.; Beattie, Patrick D.; Chau, Nguyen V.; Quang, Vo M.; Barfield, Cori; Tietje, Kathy; Steele, Matt; Weigl, Bernhard H. (Public Library of Science, 2013-09)
    Monitoring for drug-induced liver injury (DILI) via serial transaminase measurements in patients on potentially hepatotoxic medications (e.g., for HIV and tuberculosis) is routine in resource-rich nations, but often ...
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