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Browsing MIT Open Access Articles by Title

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  • Wyatt, John L.; Mendoza, Oscar D.; Kelly, Shawn K.; Doyle, Patrick S.; Shire, Douglas B.; Gingerich, Marcus D.; Chen, Jinghua; Cogan, Stuart F.; Drohan, William A.; Theogarajan, Luke; Rizzo, Joseph F. (SPIE, 2010-02)
    This presentation concerns the engineering development of the Boston visual prosthesis for restoring useful vision to patients blind with degenerative retinal disease. A miniaturized, hermetically-encased, 15-channel ...
  • Chan, Juliana Maria; Rhee, June-Wha; Drum, Chester L.; Bronson, Roderick T.; Golomb, Gershon; Langer, Robert; Farokhzad, Omid C. (National Academy of Sciences, 2011-11)
    Following recent successes with percutaneous coronary intervention (PCI) for treating coronary artery disease (CAD), many challenges remain. In particular, mechanical injury from the procedure results in extensive endothelial ...
  • Wirth, Dyann; Daily, Johanna; Winzeler, Elizabeth; Mesirov, Jill P.; Regev, Aviv (National Academy of Sciences, 2009-07)
    Lemieux et al. (1) describe a reanalysis of our in vivo Plasmodium falciparum patient samples (2), supporting many of our conclusions (exclusive presence of rings, lack of distinct asexual phases in the clusters, a relation ...
  • Motz, Jason T.; Fitzmaurice, Maryann; Miller, Arnold; Gandhi, Saumil J.; Haka, Abigail S.; Galindo, Luis H.; Kramer, John R.; Feld, Michael S.; Dasari, Ramachandra Rao (SPIE, 2006-04)
    The rupture of vulnerable atherosclerotic plaque accounts for the majority of clinically significant acute cardiovascular events. Because stability of these culprit lesions is directly related to chemical and morphological ...
  • Menolascina, Filippo; Fiore, Gianfranco; Orabona, Emanuele; De Stefano, Luca; Ferry, Mike; Hasty, Jeff; di Bernardo, Mario; di Bernardo, Diego (Public Library of Science, 2014-05)
    We describe an innovative experimental and computational approach to control the expression of a protein in a population of yeast cells. We designed a simple control algorithm to automatically regulate the administration ...
  • Ho, Emily E.; Dubrovsky, Esther; Gertler, Frank; Meacham, Meacham; Hemann, Michael (Nature Publishing Group, 2009-09)
    Mouse models have markedly improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic experimentation. Here, we report ...
  • Lau, Ken S.; Lauffenburger, Douglas A.; Juchheim, Alwin M.; Cavaliere, Kimberly R.; Philips, Sarah R.; Haigis, Kevin M. (American Association for the Advancement of Science (AAAS), 2011-03)
    Cellular responses to external stimuli depend on dynamic features of multipathway network signaling; thus, cell behavior is influenced in a complex manner by the environment and by intrinsic properties. Methods of multivariate ...
  • Zheng, Yiran; Stephan, Matthias T.; Gai, S. Annie; Abraham, Wuhbet; Shearer, Adrianne; Irvine, Darrell J.; Zheng, Yiran (Elsevier, 2013-06)
    In adoptive cell therapy (ACT), autologous tumor-specific T-cells isolated from cancer patients are activated and expanded ex vivo, then infused back into the individual to eliminate metastatic tumors. A major limitation ...
  • Agrawal, Rohit; Musiker, Gregg; Sotirov, Vladimir; Wei, Fan (Electronic Journal of Combinatorics, 2013-09)
    We elaborate upon a bijection discovered by Cools, Draisma, Payne, and Robeva (2012) between the set of rectangular standard Young tableaux and the set of equivalence classes of chip configurations on certain metric graphs ...
  • Lamata, L.; Leibrant, David R.; Chuang, Isaac L.; Cirac, J. I.; Lukin, M. D.; Vuletic, Vladan; Yelin, S. F. (American Physical Society, 2011-07)
    A new approach for the realization of a quantum interface between single photons and single ions in an ion crystal is proposed and analyzed. In our approach the coupling between a single photon and a single ion is enhanced ...
  • Schulz, Norbert S.; Canizares, Claude R.; Lee, Julia C.; Sako, Masao (IOP Publishing, 2001-12)
    We present a first analysis of a high-resolution X-ray spectrum of the ionized stellar wind of Vela X-1 during eclipse. The data were obtained with the High-Energy Transmission Grating Spectrometer on board the Chandra ...
  • Landreman, Matt; Fulop, T. (American Physical Society, 2013-07)
    Runaway ions can be produced in plasmas with large electric fields, where the accelerating electric force is augmented by the low mean ionic charge due to the imbalance between the number of electrons and ions. Here we ...
  • Gardikis, Georgios; Xilouris, George; Montpetit, Marie-Jose; Vanelli-Coralli, Alessandro; Negru, Daniel (Hindawi Publishing Corporation, 2010-12)
    The vision of the Internet of the Future for service ubiquity dictates that end users should be able to access services—mostly media-oriented ones—at any time from a variety of networks, including mobile, broadband, and ...
  • Tierney, Patrick L.; Koretsky, Alan P.; Walters, Judith R.; Leopold, David A.; Yu, David; Chuang, Kai-Hsiang; Conroy, Richard S.; Bergstrom, Debra A.; Pelled, Galit (United States National Academy of Sciences, 2009-08)
    In the weeks following unilateral peripheral nerve injury, the deprived primary somatosensory cortex (SI) responds to stimulation of the ipsilateral intact limb as demonstrated by functional magnetic resonance imaging ...
  • Montpetit, Marie-Jose (Institute of Electrical and Electronics Engineers, 2009-08)
    This keynote address wants to establish the current status of IPTV and define how it will evolve with the new ubiquity of Internet video and smartphones with Web access. In particular, the discussion centers on how IPTV ...
  • Fischer, Michael M. J. (Berg Publishers, 2009-03)
    Twelve cartoons, published in the Danish newspaper Jyllands-Posten in September 2005, nine cartoons published in the Tehran newspaperIran in May 2006, and two hundred eighty-two cartoons curated in Tehran in September 2006 ...
  • Hur, Kyu Yeon; So, Jae-Seon; Frank-Kamenetsky, Maria; Fitzgerald, Kevin; Koteliansky, Victor; Iwawaki, Takao; Lee, Ann-Hwee; Ruda, Vera; Glimcher, Laurie H. (Rockefeller University Press, The, 2012-01)
    The mammalian stress sensor IRE1α plays a central role in the unfolded protein, or endoplasmic reticulum (ER), stress response by activating its downstream transcription factor XBP1 via an unconventional splicing mechanism. ...
  • Emtage, Lesley; Aziz-Zaman, Sonya; Padovan-Merhar, Olivia; Horvitz, H. Robert; Fang-Yen, Christopher; Ringstad, Niels (Society for Neuroscience, 2012-11)
    To identify molecular mechanisms that function in G-protein signaling, we have performed molecular genetic studies of a simple behavior of the nematode Caenorhabditis elegans, egg laying, which is driven by a pair of ...
  • Fenning, David P.; Hofstetter, J.; Bertoni, Mariana I.; Hudelson, S.; Rinio, M.; Lelievre, J. F.; Lai, B.; del Canizo, C.; Buonassisi, Tonio (American Institute of Physics (AIP), 2011-04)
    The evolution during silicon solar cell processing of performance-limiting iron impurities is investigated with synchrotron-based x-ray fluorescence microscopy. We find that during industrial phosphorus diffusion, bulk ...
  • Parsons, Andrew T.; Senecal, Todd D.; Buchwald, Stephen Leffler (Wiley Blackwell, 2012-02)
    Exchanging BF[subscript 3] by CF[subscript 3]: The title reaction proceeds under exceedingly mild reaction conditions and provides 2-arylvinyl- and 2-heteroarylvinyl-substituted substrates with E/Z selectivities of more ...
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