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Browsing MIT Open Access Articles by Title

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  • Iwasa, Yukikazu; Bascunan, Juan; Hahn, Seung-Yong; Tomita, Masaru; Yao, Weijun (Institute of Electrical and Electronics Engineers (IEEE), 2010-06)
    This paper describes the NMR/MRI magnets that are currently being developed at the MIT Francis Bitter Magnet Laboratory: 1) a 1.3 GHz NMR magnet; 2) a compact NMR magnet assembled from YBCO annuli; and 3) a persistent-mode, ...
  • Wang, Fa; Xiang, Yuan-Yuan; Wang, Da; Wang, Qiang-Hua; Lee, Dung-Hai (American Physical Society, 2012-10)
    In several recent experiments the superconducting gap of a single-unit-cell-thick FeSe film on SrTiO[subscript 3] substrate has been observed by scanning tunneling spectroscopy and angle-resolved photoemission spectroscopy. ...
  • Oberoi, Divya; Evarts, Eric R.; Rogers, Alan E. E. (Springer, 2009-10)
    We report very high temporal and spectral resolution interferometric observations of some unusual solar radio bursts near 1420 MHz. These bursts were observed on 13 September 2005, 22 minutes after the peak of a GOES ...
  • Liao, Bolin; Esfarjani, Keivan; Chen, Gang; Zhang, Qian; Lan, Yucheng; Lukas, Kevin; Liu, Weishu; Opeil, Cyril; Broido, David; Ren, Zhifeng (National Academy of Sciences (U.S.), 2013-07)
    From an environmental perspective, lead-free SnTe would be preferable for solid-state waste heat recovery if its thermoelectric figure-of-merit could be brought close to that of the lead-containing chalcogenides. In this ...
  • Sze, Vivienne; Chandrakasan, Anantha P. (Institute of Electrical and Electronics Engineers, 2009-11)
    Enabling parallel processing is becoming increasingly necessary for video decoding as performance requirements continue to rise due to growing resolution and frame rate demands. It is important to address known bottlenecks ...
  • Garber, Manuel; Yosef, Nir; Goren, Alon; Raychowdhury, Raktima; Thielke, Anne; Guttman, Mitchell; Robinson, James; Minie, Brian; Chevrier, Nicolas; Itzhaki, Zohar; Blecher-Gonen, Ronnie; Bornstein, Chamutal; Amann-Zalcenstein, Daniela; Weiner, Assaf; Friedrich, Dennis; Meldrim, James; Ram, Oren; Cheng, Christine; Gnirke, Andreas; Fisher, Sheila; Friedman, Nir; Wong, Bang; Bernstein, Bradley E.; Nusbaum, Chad; Hacohen, Nir; Regev, Aviv; Amit, Ido (Elsevier, 2012-08)
    Understanding the principles governing mammalian gene regulation has been hampered by the difficulty in measuring in vivo binding dynamics of large numbers of transcription factors (TF) to DNA. Here, we develop a high-throughput ...
  • Angelosanto, Jill; Brosnahan, Kathleen; Ross, Kenneth; Hahn, Cynthia; Russell, Kate; Drury, Linda; Norton, Stephanie; Nadler, Lee; Stegmaier, Kimberly; Haining, W. Nicholas (BioMed Central Ltd, 2008-08)
    Background: The differentiation of naive T and B cells into memory lymphocytes is essential for immunity to pathogens. Therapeutic manipulation of this cellular differentiation program could improve vaccine efficacy and ...
  • Pardo-Martin, Carlos; Allalou, Amin Mohamed; Medina, Jaime; Eimon, Peter; Wählby, Carolina; Yanik, Mehmet Fatih (Nature Publishing Group, 2013-02)
    Most gene mutations and biologically active molecules cause complex responses in animals that cannot be predicted by cell culture models. Yet animal studies remain too slow and their analyses are often limited to only a ...
  • Pardo-Martin, Carlos; Chang, Tsung-Yao; Koo, Bryan Kyo; Gilleland, Cody Lee; Wasserman, Steven Charles; Yanik, Mehmet Fatih (Nature Publishing Group, 2010-07)
    We demonstrate a high-throughput platform for cellular-resolution in vivo chemical and genetic screens on zebrafish larvae. The system automatically loads zebrafish from reservoirs or multiwell plates, and positions and ...
  • Xu, Feng; Beyazoglu, Turker; Emre, Ahmet E.; Hefner, Evan; Manzur, Tariq; Demirci, Utkan; Moon, SangJun (Society of Photo-optical Instrumentation Engineers, 2010-04)
    Cell-based biosensors (CBBs) have important applications in biosecurity and rapid diagnostics. Current CBB technologies have challenges including cell immobilization on the sensors, high throughput fabrication and portability, ...
  • Kothapalli, Chandrasekhar R.; Van Veen, Ed; de Valence, Sarra; Chung, Seok; Zervantonakis, Ioannis; Gertler, Frank; Kamm, Roger Dale (Royal Society of Chemistry, 2010-11)
    Studying neurite guidance by diffusible or substrate bound gradients is challenging with current techniques. In this study, we present the design, fabrication and utility of a microfluidic device to study neurite guidance ...
  • Rohde, Christopher Benjamin; Gilleland, Cody Lee; Samara, Chrysanthi; Yanik, Mehmet Fatih (SPIE, 2010-02)
    Therapeutic treatment of spinal cord injuries, brain trauma, stroke, and neurodegenerative diseases will greatly benefit from the discovery of compounds that enhance neuronal regeneration following injury. We previously ...
  • Chen, Chia-Hung; Miller, Miles Aaron; Sarkar, Aniruddh; Beste, Michael T.; Lauffenburger, Douglas A.; Griffith, Linda G.; Han, Jongyoon (2012-10)
    In this study, we integrated several components, including a droplet generator, a pico-injector, and an analytical inference technique, Proteolytic Activity Matrix Analysis (PrAMA), to create a platform for assessing ...
  • Yew, Elijah Y.S.; So, Peter T. C.; Rowlands, Christopher James; Yew, Elijah Y.S. (Elsevier, 2013-12)
    High-resolution microscopy methods based on different nonlinear optical (NLO) contrast mechanisms are finding numerous applications in biology and medicine. While the basic implementations of these microscopy methods are ...
  • Samara, Chrysanthi; Gilleland, Cody Lee; Zeng, Fei; Rohde, Christopher Benjamin; Yanik, Mehmet Fatih (Society of Photo-optical Instrumentation Engineers, 2009-02)
    In recent years, the advantages of using small invertebrate animals as model systems for human disease have become increasingly apparent and have resulted in three Nobel Prizes in medicine or chemistry during the last six ...
  • Zhao, Wen-Ning; Cheng, Chialin; Theriault, Kraig M.; Sheridan, Steven D.; Tsai, Li-Huei; Haggarty, Stephen J. (Sage Publications, 2012-08)
    Wnt/β-catenin signaling has emerged as a central player in pathways implicated in the pathophysiology and treatment of neuropsychiatric disorders. To identify potential novel therapeutics for these disorders, high-throughput ...
  • Cox, David D.; Pinto, Nicolas; Doukhan, David; DiCarlo, James (Public Library of Science, 2009-11)
    While many models of biological object recognition share a common set of ‘‘broad-stroke’’ properties, the performance of any one model depends strongly on the choice of parameters in a particular instantiation of that ...
  • Pinto, Nicolas; Doukhan, David; DiCarlo, James; Cox, David D. (Public Library of Science, 2009-11)
    While many models of biological object recognition share a common set of “broad-stroke” properties, the performance of any one model depends strongly on the choice of parameters in a particular instantiation of that ...
  • Armiento, R.; Kozinsky, B.; Hautier, G.; Fornari, M.; Ceder, Gerbrand (American Physical Society, 2014-04)
    We screen a large chemical space of perovskite alloys for systems with optimal properties to accommodate a morphotropic phase boundary (MPB) in their composition-temperature phase diagram, a crucial feature for high ...
  • Steinmeyer, Joseph Daly; Yanik, Mehmet Fatih (Public Library of Science, 2012-04)
    The complexity of neurons and neuronal circuits in brain tissue requires the genetic manipulation, labeling, and tracking of single cells. However, current methods for manipulating cells in brain tissue are limited to ...
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