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Browsing MIT Open Access Articles by Title

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  • Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors 
    Mohr, Justin T.; Speers, Anna E.; Wan, Chu; Spicer, Timothy P.; Fernandez-Vega, Virneliz; Chase, Peter; Hodder, Peter S.; Schürer, Stephan C.; Nomura, Daniel K.; Rosen, Hugh; Cravatt, Benjamin F.; Bachovchin, Daniel A.; Berlin, Jacob M.; Fu, Gregory C. (National Academy of Sciences, 2011-03)
    National Institutes of Health (NIH)-sponsored screening centers provide academic researchers with a special opportunity to pursue small-molecule probes for protein targets that are outside the current interest of, or beyond ...
  • ac and dc current-induced motion of a 360 degrees domain wall 
    Mascaro, Mark D.; Ross, Caroline A. (American Physical Society, 2010-12)
    he response of 360° [360 degrees]domain walls in narrow magnetic stripes to applied dc and ac currents, investigated by micromagnetic simulation, differs qualitatively from the response of 180° [180 degrees] domain walls. ...
  • Accelerated Dual Descent for Network Optimization 
    Zargham, Michael; Ribeiro, Alejandro; Ozdaglar, Asuman E.; Jadbabaie, Ali (IEEE Control Systems Society, 2011-06)
    Dual descent methods are commonly used to solve network optimization problems because their implementation can be distributed through the network. However, their convergence rates are typically very slow. This paper ...
  • Accelerated on-line calibration of dynamic traffic assignment using distributed stochastic gradient approximation 
    Huang, Enyang; Antoniou, Constantinos; Lopes, Jorge; Wen, Yang; Ben-Akiva, Moshe E. (Institute of Electrical and Electronics Engineers, 2010-09)
    Dynamic Traffic Assignment (DTA) system [Ben-Akiva et al., 1991] [Mahmassani, 2001] benefits travelers by providing accurate estimate of current traffic conditions, consistent anticipatory network information as well as ...
  • Accelerated Orbital Expansion and Secular Spin-down of the Accreting Millisecond Pulsar Sax J1808.4−3658 
    Patruno, Alessandro; Bult, Peter; Gopakumar, Achamveedu; Hartman, Jacob M.; Wijnands, Rudy; van der Klis, Michiel; Chakrabarty, Deepto (IOP Publishing, 2012-02)
    The accreting millisecond pulsar SAX J1808.4–3658 has shown a peculiar orbital evolution in the past with an orbital expansion much faster than expected from standard binary evolutionary scenarios. Previous limits on the ...
  • Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice 
    Gertler, Frank; Veen, Ed van; Ma, Chi Him Eddie; Omura, Takao; Cobos, Enrique J.; Latrémolière, Alban; Ghasemlou, Nader; Brenner, Gary J.; Barrett, Lee; Sawada, Tomokazu; Gao, Fuying; Coppola, Giovanni; Costigan, Michael; Geschwind, Dan; Woolf, Clifford J. (American Society for Clinical Investigation, 2011-10)
    Although peripheral nerves can regenerate after injury, proximal nerve injury in humans results in minimal restoration of motor function. One possible explanation for this is that injury-induced axonal growth is too slow. ...
  • Accessing the public MIMIC-II intensive care relational database for clinical research 
    Scott, Daniel; Lee, Joon; Silva, Ikaro; Park, Shinhyuk; Moody, George B.; Celi, Leo Anthony G.; Mark, Roger Greenwood (BioMed Central Ltd, 2013-01)
    Background: The Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC-II) database is a free, public resource for intensive care research. The database was officially released in 2006, and has attracted a growing ...
  • Access-network association policies for media streaming in heterogeneous environments 
    Parandehgheibi, Ali; Medard, Muriel; Ozdaglar, Asuman E.; Shakkottai, Srinivas (Institute of Electrical and Electronics Engineers, 2010-12)
    We study the design of media streaming applications in the presence of multiple heterogeneous wireless access methods with different throughputs and costs. Our objective is to analytically characterize the trade-off between ...
  • Accountability and Flexibility in Public Schools: Evidence from Boston's Charters and Pilots 
    Abdulkadiroglu, Atila; Angrist, Joshua; Dynarski, Susan M.; Kane, Thomas J.; Pathak, Parag (President and Fellows of Harvard College, 2011-03)
    We use student assignment lotteries to estimate the effect of charter school attendance on student achievement in Boston. We also evaluate a related alternative, Boston's pilot schools. Pilot schools have some of the ...
  • Accretion of a Terrestrial-Like Minor Planet by a White Dwarf 
    Melis, Carl; Farihi, J.; Dufour, P.; Zuckerman, B.; Burgasser, Adam; Bergeron, P.; Bochanski, J.; Simcoe, Robert A. (Institute of Physics Publishing, 2011-04)
    We present optical and infrared characterization of the polluted DAZ white dwarf GALEX J193156.8+011745. Imaging and spectroscopy from the ultraviolet to the thermal infrared indicate that this white dwarf hosts excess ...
  • Accuracy of density functional theory in predicting formation energies of ternary oxides from binary oxides and its implication on phase stability 
    Hautier, Geoffroy; Ong, Shyue Ping; Jain, Anubhav; Moore, Charles Jacob; Ceder, Gerbrand (American Physical Society, 2012-04)
    The evaluation of reaction energies between solids using density functional theory (DFT) is of practical importance in many technological fields and paramount in the study of the phase stability of known and predicted ...
  • Accuracy of the post-Newtonian approximation. II. Optimal asymptotic expansion of the energy flux for quasicircular, extreme mass-ratio inspirals into a Kerr black hole 
    Zhang, Zhongyang; Berti, Emanuele; Yunes, Nicolas (American Physical Society, 2011-07)
    We study the effect of black hole spin on the accuracy of the post-Newtonian approximation. We focus on the gravitational energy flux for the quasicircular, equatorial, extreme mass-ratio inspiral of a compact object into ...
  • Accurate Determination of Interstrand Distances and Alignment in Amyloid Fibrils by Magic Angle Spinning NMR 
    Bajaj, Vikram S.; Caporini, Marc A.; Griffin, Robert Guy; Veshtort, Mikhail; Dobson, Christopher M.; Fitzpatrick, Anthony; MacPhee, Cait E.; Vendruscolo, Michele (American Chemical Society (ACS), 2010-10)
    Amyloid fibrils are structurally ordered aggregates of proteins whose formation is associated with many neurodegenerative and other diseases. For that reason, their high-resolution structures are of considerable interest ...
  • Accurate FDTD simulation of anisotropic media by subpixel smoothing 
    Oskooi, Ardavan F.; Kottke, Chris; Johnson, Steven G. (Optical Society of America, 2009-09)
    Finite-difference time-domain (FDTD) methods suffer from reduced accuracy when discretizing discontinuous materials. We previously showed that accuracy can be significantly improved by using subpixel smoothing of the ...
  • Accurate Geo-Referencing Method for AUVs for Oceanographic Sampling 
    Khan, Rubaina R.; Taher, Tawfiq; Hover, Franz S. (Institute of Electrical and Electronics Engineers (IEEE), 2010-09)
    The objective of the paper is to understand, characterize and enhance the achievable performance of the system of a state-of-the-art marine observation device, the Oceanserver IVER2 Autonomous Underwater Vehicle(AUV), in ...
  • Accurate, Low-Energy Trajectory Mapping for Mobile Devices 
    Thiagarajan, Arvind; Ravindranath, Lenin; Balakrishnan, Hari; Madden, Samuel R.; Girod, Lewis D. (USENIX Association, 2011-03)
    CTrack is an energy-efficient system for trajectory mapping using raw position tracks obtained largely from cellular base station fingerprints. Trajectory mapping, which involves taking a sequence of raw position samples ...
  • Achieving a Strongly Temperature-Dependent Casimir Effect 
    Rodriguez, Alejandro W.; Woolf, David; McCauley, Alexander Patrick; Capasso, Federico; Joannopoulos, John D.; Johnson, Steven G. (American Physical Society, 2010-08)
    We propose a method of achieving large temperature T sensitivity in the Casimir force that involves measuring the stable separation between dielectric objects immersed in a fluid. We study the Casimir force between slabs ...
  • Achieving bounded delay on a time-varying satellite uplink 
    Wysocarski, Jeffrey S.; Sun, Jun; Wang, Mu-Cheng; Jackson, Crystal (Institute of Electrical and Electronics Engineers, 2010-01)
    In this paper, we investigate the packet transmission delay in a time varying satellite uplink. Specifically, we are interested in bounding the packet transmission delay within the terminal router for uplink traffic in a ...
  • Achieving high-precision pointing on ExoplanetSat: Initial feasibility analysis 
    Pong, Christopher Masaru; Lim, Sungyung; Smith, Matthew William; Miller, David W.; Villasenor, Jesus Noel Samonte; Seager, Sara (SPIE, 2010-07)
    ExoplanetSat is a proposed three-unit CubeSat designed to detect down to Earth-sized exoplanets in an orbit out to the habitable zone of Sun-like stars via the transit method. To achieve the required photometric precision ...
  • Achieving the Holevo bound via sequential measurements 
    Giovannetti, Vittorio; Maccone, Lorenzo; Lloyd, Seth (American Physical Society (APS), 2012-01)
    We present a decoding procedure to transmit classical information in a quantum channel which, saturating asymptotically the Holevo bound, achieves the optimal rate of the communication line. In contrast to previous proposals, ...
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