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Browsing MIT Open Access Articles by Title

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  • Dong, Hongping; Chang, David C.; Ho, Chia-Hua; Lim, Siew Pheng; Chionh, Yok Hian; Hia, Fabian; Lee, Yie Hou; Kukkaro, Petra; Lok, Shee-Mei; Dedon, Peter C.; Shi, Pei-Yong (Public Library of Science, 2012-04)
    RNA modification plays an important role in modulating host-pathogen interaction. Flavivirus NS5 protein encodes N-7 and 2′-O methyltransferase activities that are required for the formation of 5′ type I cap (m[superscript ...
  • Walsh, Martin J.; Brimacombe, Kyle R.; Veith, Henrike; Bougie, James M.; Daniel, Thomas; Leister, William; Cantley, Lewis C.; Israelsen, William J.; Vander Heiden, Matthew G.; Shen, Min; Auld, Douglas S.; Thomas, Craig J.; Boxer, Matthew B. (Elsevier, 2011-09)
    Compared to normal differentiated cells, cancer cells have altered metabolic regulation to support biosynthesis and the expression of the M2 isozyme of pyruvate kinase (PKM2) plays an important role in this anabolic ...
  • Do, Loi Hung; Lippard, Stephen J. (American Chemical Society (ACS), 2009-10)
    A series of 2-phenoxypyridyl and 2-phenoxyimino ligands, H[subscript 2]L[superscript R,R′] [2,2′-(5,5′-(1,2-phenylenebis(ethyne-2,1-diyl))bis(pyridine-5,2-diyl))diphenol, where R = H, Me, or t-Bu, and R′ = H or Ph] and ...
  • Mailoa, Jonathan P.; Bailie, Colin D.; Johlin, Eric Carl; Hoke, Eric T.; Akey, Austin J.; Nguyen, William H.; McGehee, Michael D.; Buonassisi, Tonio (American Institute of Physics (AIP), 2015-03)
    With the advent of efficient high-bandgap metal-halide perovskite photovoltaics, an opportunity exists to make perovskite/silicon tandem solar cells. We fabricate a monolithic tandem by developing a silicon-based interband ...
  • Lunnan, Ragnhild; Casey, Andrew R.; Norris, John E.; Wyse, Rosemary F. G.; Gilmore, Gerard; Frebel, Anna L. (IOP Publishing, 2013-06)
    We present a chemical abundance analysis of 300S-1, the brightest likely member star of the 300 km s[superscript –1] stream near the faint satellite galaxy Segue 1. From a high-resolution Magellan/MIKE spectrum, we determine ...
  • Kim, Dae-Hyun; del Alamo, Jesus A. (Institute of Electrical and Electronics Engineers, 2010-07)
    We present 30-nm InAs pseudomorphic HEMTs (PHEMTs) on an InP substrate with record fT characteristics and well-balanced fT and f[subscript max] values. This result was obtained by improving short-channel effects through ...
  • Kim, Tae-Woo; Kim, Dae-Hyun; del Alamo, Jesus A. (Institute of Electrical and Electronics Engineers, 2010-03)
    We have fabricated 30 nm In0.7Ga0.3As Inverted-Type HEMTs with outstanding logic performance, scalability and high frequency characteristics. The motivation for this work is the demonstration of reduced gate leakage current ...
  • Osgood, Richard M.; Kimball, B. R.; Geis, Michael W.; Turner, George W.; Lyszczarz, Theodore M.; Molnar, Richard J. (SPIE, 2010-02)
    The optical switching times of liquid-crystal cells using 5CB, 5OCB and PCH5 liquid crystal materials have been characterized as a function of applied voltage, V, and temperature, T. The transition time from 90 to 10 % ...
  • Cardin, Michel-Alexandre; de Neufville, Richard (Wiley Blackwell, 2014-11)
    This paper proposes and demonstrates design catalogues as a computationally efficient method for identifying improved designs for complex technological systems. This new process significantly speeds up the analysis of ...
  • Cho, Taeg Sang; Lee, Kyeong-Jae; Kong, Jing; Chandrakasan, Anantha P. (Institute of Electrical and Electronics Engineers, 2009-01)
    This paper presents an energy-efficient chemical sensor system that uses carbon nanotubes (CNT) as the sensing medium. The room-temperature operation of CNT sensors eliminates the need for micro hot-plate arrays, which ...
  • Drake, Jeremy J.; Ratzlaff, Peter; Kashyap, Vinay; Huenemoerder, David P.; Wargelin, Bradford J.; Pease, Deron O. (IOP Publishing, 2014-02)
    Extensive X-ray and EUV photometric observations of the eclipsing RS CVn system AR Lac were obtained over the years 1997-2013 with the Chandra X-Ray Observatory Extreme-Ultraviolet Explorer (EUVE). During primary eclipse, ...
  • Qazi, Masood; Amerasekera, Ajith; Chandrakasan, Anantha P. (Institute of Electrical and Electronics Engineers (IEEE), 2013-10)
    In order to realize a digital system with no distinction between “on” and “off,” the computational state must be stored in nonvolatile memory elements. If the energy cost and time cost of managing the computational state ...
  • Qazi, Masood; Chandrakasan, Anantha P.; Amerasekera, Ajith (Institute of Electrical and Electronics Engineers (IEEE), 2013-02)
    Nonvolatile processing-continuously operating a digital circuit and retaining state through frequent power interruptions-creates new applications for portable electronics operating from harvested energy and high-performance ...
  • Dawson, Joel L.; Chandrakasan, Anantha P.; Bohorquez, Jose L. (Institute of Electrical and Electronics Engineers, 2009-03)
    Recent advances in the medical field are spurring the need for ultra-low power transceivers for wireless communication with medical implants. To deal with the growing demand for medical telemetry, the FCC commissioned the ...
  • Kim, Jun Ki; Yun, Seok Hyun (Andy); Choi, Jin Woo (SPIE, 2013-04)
    Miniature endoscopic probes offer a solution for deep brain imaging by overcoming the limited depth of intravital microscopy. We describe a small-diameter (350 μm) graded-index optical probe with a side-view design for in ...
  • Ren, Y.; de Visser, P. J.; Hovenier, J. N.; Zhang, W.; Gao, J. R.; Klapwijk, T. M.; Shi, S. C.; Kao, T.-Y.; Kumar, S.; Reno, J. L.; Hu, Qing (2011-04)
    We report a set of measurements to demonstrate a new type of surface emitting distributed feedback (DFB) quantum cascade laser (QCL) operated at 3.5 THz as a local oscillator by pumping a superconducting hot-electron ...
  • Zhang, Jinshuo; Siddiqui, Saima Afroz; Ho, Pin; Currivan, Jean Anne; Lage, Enno; Bono, David C; Baldo, Marc A; Ross, Caroline A (IOP Publishing, 2016-05)
    The formation of 360° magnetic domain walls (360DWs) in Co and Ni[subscript 80]Fe[subscript 20] thin film wires was demonstrated experimentally for different wire widths, by successively injecting two 180° domain walls ...
  • Kamakshi, Divya Akella; Shrivastava, Aatmesh; Duan, Chuhong; Calhoun, Benton H. (MDPI AG (Basel, Switzerland), 2016-05)
    We propose a fully on-chip clock-source system in which an ultra-low-power diode-based temperature-uncompensated oscillator (OSC[ subscript diode]) serves as the main clock source and frequency locks to a higher-power ...
  • Oklu, Rahmi; Zhang, Yu Shrike; Yue, Kan; Aleman, Julio; Mollazadeh-Moghaddam, Kamyar; Bakht, Syeda Mahwish; Yang, Jingzhou; Jia, Weitao; Dell’Erba, Valeria; Assawes, Pribpandao; Shin, Su Ryon; Dokmeci, Mehmet R.; Khademhosseini, Alireza (Springer US, 2016-04)
    The field of regenerative medicine has progressed tremendously over the past few decades in its ability to fabricate functional tissue substitutes. Conventional approaches based on scaffolding and microengineering are ...
  • Ji, Xiong; Powell, Benjamin E.; Shachar, Sigal; Hnisz, Denes; Pegoraro, Gianluca; Lee, Tong Ihn; Misteli, Tom; Dadon, Daniel Benjamin; Fan, Zi Peng; Borges-Rivera, Diego Ramon; Weintraub, Abraham Selby; Jaenisch, Rudolf; Young, Richard A (Elsevier, 2015-12)
    In this study, we describe the 3D chromosome regulatory landscape of human naive and primed embryonic stem cells. To devise this map, we identified transcriptional enhancers and insulators in these cells and placed them ...
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