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Browsing MIT Open Access Articles by Title

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  • Kim, Tae-Woo; Kim, Dae-Hyun; del Alamo, Jesus A. (Institute of Electrical and Electronics Engineers (IEEE), 2010-12)
    We have developed a new self-aligned gate technology for InGaAs High Electron Mobility Transistors with non-alloyed Mo-based ohmic contacts and a very low parasitic capacitance gate design. The new process delivers a contact ...
  • Verma, Naveen; Ramadass, Yogesh Kumar; Kwong, Joyce; Chandrakasan, Anantha P. (Institute of Electrical and Electronics Engineers, 2008-12)
    Aggressive supply voltage scaling to below the device threshold voltage provides significant energy and leakage power reduction in logic and SRAM circuits. Consequently, it is a compelling strategy for energy-constrained ...
  • Daly, Denis C.; Chandrakasan, Anantha P. (Institute of Electrical and Electronics Engineers, 2009-08)
    A 6-bit highly digital flash ADC is implemented in a 0.18 mum CMOS process. The ADC operates in the subthreshold regime down to 200 mV and employs comparator redundancy and reconfigurability to improve linearity. The ...
  • Kumar, Vijay; Park, Daniel S.; Taylor, Washington (Springer-Verlag/International School for Advanced Studies (SISSA), 2011-04)
    We systematically investigate the finite set of possible gauge groups and matter content for supergravity theories in six dimensions with no tensor multiplets, focusing on nonabelian gauge groups which are a product of ...
  • Dawson, Joel L.; Chung, SungWon (VLSI-TSA, 2009-04)
    We present a digitally assisted subsampler, designed to serve as the downconversion path in adaptive predistorters for 800MHz–5.8GHz RF power amplifiers. We use digital averaging to overcome the noise folding problems ...
  • Nguyen, Khoa M.; Kim, Helen H.; Sodini, Charles G. (Institute of Electrical and Electronics Engineers (IEEE), 2010-01)
    A 76 GHz phase-locked loop (PLL) was designed in 0.13 μm IBM BiCMOS8HP technology with the intended application of millimeter-wave imaging. The PLL has a type II second order loop filter. The voltage-controlled oscillator ...
  • Park, Matthew; Perrott, Michael H. (Institute of Electrical and Electronics Engineers, 2009-12)
    The use of a VCO-based integrator and quantizer within a continuous-time (CT) \Delta \Sigma analog-to-digital converter (ADC) structure is explored, and a custom prototype in a 0.13 \mum CMOS with a measured performance ...
  • Mercier, Patrick P.; Bandyopadhyay, Saurav; Lysaght, Andrew C.; Stankovic, Konstantina M; Chandrakasan, Anantha P.; Stankovic, Konstantina M. (Institute of Electrical and Electronics Engineers (IEEE), 2013-09)
    This paper presents an ultra-low-standby-power radio transmitter that was designed for applications with extreme energy storage and/or energy harvesting constraints. By utilizing aggressive power gating techniques within ...
  • Hirsch, Matthew; Izadi, Shahram; Raskar, Ramesh; Holtzman, Henry N. (Association for Computing Machinery (ACM), 2013-04)
    We present an 8-dimensional (8D) display that allows glasses-free viewing of 3D imagery, whist capturing and reacting to incident environmental and user controlled light sources. We demonstrate two interactive possibilities ...
  • Baker, Tania; Sauer, Robert T.; Abdelhakim, Aliaa H. (National Academy of Sciences (U.S.), 2009-09)
    A hyperstable complex of the tetrameric MuA transposase with recombined DNA must be remodeled to allow subsequent DNA replication. ClpX, a AAA+ enzyme, fulfills this function by unfolding one transpososome subunit. Which ...
  • Calvo, Jennifer; Moroski-Erkul, Catherine A.; Lake, Annabelle; Eichinger, Lindsey Wood; Shah, Dharini; Jhun, Iny; Limsirichai, Prajit; Bronson, Roderick T.; Christiani, David C.; Meira, Lisiane B.; Samson, Leona D. (Public Library of Science, 2013-04)
    Alkylating agents comprise a major class of front-line cancer chemotherapeutic compounds, and while these agents effectively kill tumor cells, they also damage healthy tissues. Although base excision repair (BER) is essential ...
  • Marino-Enriquez, Adrian; Zhang, Yi-Xiang; Sioletic, Stefano; Kozakewich, Elena; Grebliunaite, Ruta; Ou, Wen-bin; Sicinska, Ewa; Raut, Chandrajit P.; Demetri, George D.; Perez-Atayde, Antonio R.; Wagner, Andrew J.; Fletcher, Jonathan A.; Fletcher, Christopher D. M.; Look, A. Thomas; Snyder, Eric; Gutierrez, Alejandro (Proceedings of the National Academy of Sciences (PNAS), 2011-09)
    Well-differentiated liposarcoma (WDLPS), one of the most common human sarcomas, is poorly responsive to radiation and chemotherapy, and the lack of animal models suitable for experimental analysis has seriously impeded ...
  • Sasaki, Tomoyuki; Lian, Shanshan; Qi, Jie; Bayliss, Peter E.; Carr, Christopher E.; Johnson, Jennifer L.; Guha, Sujay; Kobler, Patrick; Catz, Sergio D.; Gill, Matthew; Jia, Kailiang; Klionsky, Daniel J.; Kishi, Shuji (Public Library of Science, 2014-06)
    Spinster (Spin) in Drosophila or Spinster homolog 1 (Spns1) in vertebrates is a putative lysosomal H[superscript +]-carbohydrate transporter, which functions at a late stage of autophagy. The Spin/Spns1 defect induces ...
  • Picard, Nathalie; Leslie, Jennifer H.; Trowbridge, Sara Kishi; Subramanian, Jaichandar; Nedivi, Elly; Fagiolini, Michela (Society for Neuroscience, 2014-03)
    During development, experience plays a crucial role in sculpting neuronal connections. Patterned neural activity guides formation of functional neural circuits through the selective stabilization of some synapses and the ...
  • Gipson, Theresa Anne; Housman, David E.; Sathasivam, Kirupa; Neueder, Andreas; Landles, Christian; Benjamin, Agnesska C.; Bondulich, Marie K.; Smith, Donna L.; Faull, Richard L. M.; Roos, Raymund A. C.; Howland, David; Detloff, Peter J.; bates, Gillian P. (National Academy of Sciences (U.S.), 2013-01)
    Huntington disease (HD) is a devastating, late-onset, inherited neurodegenerative disorder that manifests with personality changes, movement disorders, and cognitive decline. It is caused by a CAG repeat expansion in exon ...
  • Sathasivam, Kirupa; Neueder, Andreas; Gipson, Theresa Anne; Landles, Christian; Benjamin, Agnesska C.; Bondulich, Marie K.; Amith, Donna L.; Faull, Richard L. M.; Roos, Raymund A. C.; Howland, David; Detloff, Peter J.; Housman, David E.; Bates, Gillian P. (National Academy of Sciences (U.S.), 2013-01)
    Huntington disease (HD) is a devastating, late-onset, inherited neurodegenerative disorder that manifests with personality changes, movement disorders, and cognitive decline. It is caused by a CAG repeat expansion in exon ...
  • Greenblatt, Wesley H.; Rubenstein, Eric M.; Kreft, Stefan G.; Swanson, Robert; Hochstrasser, Mark (Rockefeller University Press, The, 2012-06)
    Little is known about quality control of proteins that aberrantly or persistently engage the endoplasmic reticulum (ER)-localized translocon en route to membrane localization or the secretory pathway. Hrd1 and Doa10, the ...
  • Ceresoli, Davide; Marzari, Nicola; Lopez, M. G.; Thonhauser, T. (American Physical Society, 2010-05)
    We extend the recently developed converse NMR approach [Thonhauser et al., J. Chem. Phys. 131, 101101 (2009)] such that it can be used in conjunction with norm-conserving, nonlocal pseudopotentials. This extension permits ...
  • Kulik, Heather J.; Steeves, Adam H.; Field, Robert W. (Elsevier ScienceDirect, 2009-08)
    Based on high-level ab initio calculations, we predict the existence of a strong 4Σ+–4Σ+ [superscript 4 sigma superscript + - superscript 4 sigma superscript +] optical transition (dav=1.6 D) [(d subscript av = 1.6 D)] ...
  • Guttman, Mitchell; Garber, Manuel; Levin, Joshua Z.; Donaghey, Julie; Robinson, James; Adiconis, Xian; Fan, Lin; Koziol, Magdalena J.; Gnirke, Andreas; Nusbaum, Chad; Rinn, John L.; Lander, Eric S.; Regev, Aviv (Nature Publishing Group, 2010-07)
    RNA-Seq provides an unbiased way to study a transcriptome, including both coding and noncoding genes. To date, most RNA-Seq studies have critically depended on existing annotations, and thus focused on expression levels ...
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