Browsing MIT Open Access Articles by Title
Now showing items 683-702 of 55765
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Acoustic mode confinement using coupled cavity structures in UHF unreleased MEMS resonators
(Springer Berlin Heidelberg, 2018-09)This papers investigates device approaches towards the confinement of acoustic modes in unreleased UHF MEMS resonators. Acoustic mode confinement is achieved using specially designed mechanically coupled acoustic cavities ... -
An acoustic remote sensing method for high-precision propeller rotation and speed estimation of unmanned underwater vehicles
(Acoustical Society of America, 2020-12-01)Understanding the dominant sources of acoustic noise in unmanned underwater vehicles (UUVs) is important for passively tracking these platforms and for designing quieter propulsion systems. This work describes how the ... -
Acoustic separation of circulating tumor cells
(National Academy of Sciences (U.S.), 2015-04)Circulating tumor cells (CTCs) are important targets for cancer biology studies. To further elucidate the role of CTCs in cancer metastasis and prognosis, effective methods for isolating extremely rare tumor cells from ... -
Acoustic streaming near a sharp structure and its mixing performance characterization
(Springer Berlin Heidelberg, 2019-08-07)Abstract Acoustic streaming can be generated in microchannels by low-frequency acoustic transducer in the vicinity of sharp structures. Close to the tip, the strong curvature induces bent trajectories on the ... -
Acoustic Voice and Speech Biomarkers of Treatment Status during Hospitalization for Acute Decompensated Heart Failure
(Multidisciplinary Digital Publishing Institute, 2023-01-31)This study investigates acoustic voice and speech features as biomarkers for acute decompensated heart failure (ADHF), a serious escalation of heart failure symptoms including breathlessness and fatigue. ADHF-related ... -
Acoustic voxels
(Association for Computing Machinery (ACM), 2016-07)Acoustic filters have a wide range of applications, yet customizing them with desired properties is difficult. Motivated by recent progress in additive manufacturing that allows for fast prototyping of complex shapes, we ... -
Acoustic-Gravity Waves Interacting with a Rectangular Trench
(Hindawi Publishing Corporation, 2015)A mathematical solution of the two-dimensional linear problem of an acoustic-gravity wave interacting with a rectangular trench, in a compressible ocean, is presented. Expressions for the flow field on both sides of the ... -
Acoustical breakdown of materials by focusing of laser-generated Rayleigh surface waves
(American Institute of Physics (AIP), 2017-07)Focusing of high-amplitude surface acoustic waves leading to material damage is visualized in an all-optical experiment. The optical setup includes a lens and an axicon that focuses an intense picosecond excitation pulse ... -
Acoustics of the one person space: headphone listening, detachable ambience, and the binaural prehistory of VR
(Informa UK Limited, 2020-04)This article traces forgotten debates over the cultural acceptability of headphone listening in order to present an audio-centric history of private virtual space. I focus on how cultural attitudes towards headphone use ... -
Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies
(Springer Science and Business Media LLC, 2018-12)Seventy percent of breast cancers express the estrogen receptor (ER), and agents that target the ER are the mainstay of treatment. However, virtually all people with ER + breast cancer develop resistance to ER-directed ... -
Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme
(Nature Publishing Group, 2011-10)Glioblastoma multiforme (GBM) is an aggressive brain tumor for which there is no cure. Overexpression of wild-type epidermal growth factor receptor (EGFR) and loss of the tumor suppressor genes Ink4a/Arf and PTEN are salient ... -
Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel
(Proceedings of the National Academy of Sciences, 2021)<jats:title>Significance</jats:title> <jats:p> Resistance to therapeutics is a challenge when treating cancer patients. Cancer can become resistant to therapies in distinct, unpredictable ways. ... -
Acquired Vitamin K Deficiency as Unusual Cause of Bleeding Tendency in Adults: A Case Report of a Nonhospitalized Student Presenting with Severe Menorrhagia
(Hindawi Publishing Corporation, 2017-08)We report a rare case of acquired vitamin K deficiency presenting with severe menorrhagia and without any gynecological problem. Partial thromboplastin time (59.2 seconds) and prothrombin time (33.1 seconds, INR: 5.97) ... -
Acquiring Fluorescence Time-lapse Movies of Budding Yeast and Analyzing Single-cell Dynamics using GRAFTS
(MyJoVE Corporation, 2013-07)Fluorescence time-lapse microscopy has become a powerful tool in the study of many biological processes at the single-cell level. In particular, movies depicting the temporal dependence of gene expression provide insight ... -
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
(Proceedings of the National Academy of Sciences, 2019-04)Carcinoma cells residing in an intermediate phenotypic state along the epithelial–mesenchymal (E–M) spectrum are associated with malignant phenotypes, such as invasiveness, tumor-initiating ability, and metastatic ... -
Acquisition of Surface EMG Using Flexible and Low-Profile Electrodes for Lower Extremity Neuroprosthetic Control
(Institute of Electrical and Electronics Engineers (IEEE), 2021)For persons with lower extremity (LE) amputation, acquisition of surface electromyography (sEMG) from within the prosthetic socket remains a significant challenge due to the dynamic loads experienced during the gait cycle. ... -
Across-species differences in pitch perception are consistent with differences in cochlear filtering
(eLife Sciences Publications, Ltd, 2019-03)Pitch perception is critical for recognizing speech, music and animal vocalizations, but its neurobiological basis remains unsettled, in part because of divergent results across species. We investigated whether species-specific ... -
Acted vs. natural frustration and delight: many people smile in natural frustration
(Institute of Electrical and Electronics Engineers, 2011-05)This work is part of research to build a system to combine facial and prosodic information to recognize commonly occurring user states such as delight and frustration. We create two experimental situations to elicit two ... -
Actin cytoskeleton: Thinking globally, actin’ locally
(Elsevier, 2000-09)A class of proteins dubbed pipmodulins bind to and sequester the phospholipid PIP2 in the plasma membrane. Local release of PIP2 controls actin dynamics in specific subcellular regions and plays a critical role in regulating ... -
Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway
(eLife Sciences Publications, Ltd., 2015-03)Wiscott Aldrich Syndrome protein (WASP) deficiency results in defects in calcium ion signaling, cytoskeletal regulation, gene transcription and overall T cell activation. The activation of WASP constitutes a key pathway ...