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Browsing MIT Open Access Articles by Title

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  • The Effects of the Inertial Properties of Above-Knee Prostheses on Optimal Stiffness, Damping, and Engagement Parameters of Passive Prosthetic Knees 
    Narang, Yashraj S.; Arelekatti, Venkata N M; Winter, Amos G. (ASME International, 2016-11)
    Our research aims to design low-cost, high-performance, passive prosthetic knees for developing countries. In this study, we determine optimal stiffness, damping, and engagement parameters for a low-cost, passive prosthetic ...
  • The effects of the interphase and strain gradients on the elasticity of layer by layer (LBL) polymer/clay nanocomposites 
    Li, Yaning; Waas, Anthony M.; Arruda, Ellen M. (Elsevier B.V., 2011-03)
    A synergistic stiffening effect observed in the elastic mechanical properties of LBL assembled polymer/clay nanocomposites is studied via two continuum mechanics approaches. The nanostructure of the representative volume ...
  • Effects of Thermal Aging on Material Properties, Stress Corrosion Cracking, and Fracture Toughness of AISI 316L Weld Metal 
    Lucas, Timothy Ryan; Forsström, Antti; Saukkonen, Tapio; Ballinger, Ronald G.; Hänninen, Hannu (Springer US, 2016-06)
    Thermal aging and consequent embrittlement of materials are ongoing issues in cast stainless steels, as well as duplex, and high-Cr ferritic stainless steels. Spinodal decomposition is largely responsible for the well-known ...
  • Effects of Threading Dislocations on AlGaN/GaN High-Electron Mobility Transistors 
    Marino, Fabio Alessio; Faralli, Nicolas; Palacios, Tomas; Ferry, David K.; Goodnick, Stephan M.; Saraniti, Marco (Institute of Electrical and Electronics Engineers, 2009-12)
    This brief aims to show the effects of threading edge dislocations on the dc and RF performance of GaN highelectron mobility transistor (HEMT) devices. A state-of-the-art high-frequency and high-power HEMT was investigated ...
  • Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection 
    Kosmrlj, Andrej; Read, Elizabeth L.; Qi, Ying; Allen, Todd M.; Altfeld, Marcus; Deeks, Steven G.; Pereyra, Florencia; Carrington, Mary; Walker, Bruce D.; Chakraborty, Arup K. (Nature Publishing Group, 2010-05)
    Without therapy, most people infected with human immunodeficiency virus (HIV) ultimately progress to AIDS. Rare individuals (‘elite controllers’) maintain very low levels of HIV RNA without therapy, thereby making disease ...
  • Effects of Time Pressure on the Use of an Automated Decision Support System for Strike Planning 
    Cummings, M. L.; Boussemart, Yves; Donmez, Birsen; Las Fargeas, Jonathan C. (Curran Associates, Inc., 2009-04)
    This paper describes the results of an experiment designed to examine the effects of time pressure on behavioral patterns. The main research hypothesis is that people under time pressure tend to increasingly rely on ...
  • Effects of topological constraints on globular polymers 
    Imakaev, Maksim Viktorovich; Tchourine, Konstantin M.; Nechaev, Sergei K.; Mirny, Leonid A. (Royal Society of Chemistry, 2015-01)
    Topological constraints can affect both equilibrium and dynamic properties of polymer systems and can play a role in the organization of chromosomes. Despite many theoretical studies, the effects of topological constraints ...
  • Effects of tunneling on groundwater flow and swelling of clay-sulfate rocks 
    Butscher, Christoph; Einstein, Herbert H.; Huggenberger, Peter (American Geophysical Union (AGU), 2011-11)
    [1] Swelling of clay-sulfate rocks is a major threat in tunneling. It is triggered by the transformation of the sulfate mineral anhydrite into gypsum as a result of water inflow in anhydrite-containing layers after tunnel ...
  • Effects of ultrasound and sodium lauryl sulfate on the transdermal delivery of hydrophilic permeants: Comparative in vitro studies with full-thickness and split-thickness pig and human skin 
    Seto, Jennifer E.; Polat, Baris E.; Blankschtein, Daniel; Langer, Robert; Lopez, Renata F. V. (Elsevier, 2010-03)
    The simultaneous application of ultrasound and the surfactant sodium lauryl sulfate (referred to as US/SLS) to skin enhances transdermal drug delivery (TDD) in a synergistic mechanical and chemical manner. Since full-thickness ...
  • Effects of unilateral robotic limb loading on gait characteristics in subjects with chronic stroke 
    Khanna, Ira; Roy, Anindo; Rodgers, Mary M.; Krebs, Hermano Igo; Macko, Richard M.; Forrester, Larry W. (BioMed Central Ltd, 2010-05)
    Background Hemiparesis after stroke often leads to impaired ankle motor control that impacts gait function. In recent studies, robotic devices have been developed to address this impairment. While capable of imparting ...
  • Effects of unilateral robotic limb loading on gait characteristics in subjects with chronic stroke 
    Khanna, Ira; Roy, Anindo; Krebs, Hermano Igo; Rodger, Mary M.; Macko, Richard M.; Forrester, Larry W. (BioMed Central Ltd, 2010-05)
    Background Hemiparesis after stroke often leads to impaired ankle motor control that impacts gait function. In recent studies, robotic devices have been developed to address this impairment. While capable of imparting ...
  • Effects of Upstream Wake Phasing on Transonic Axial Compressor Performance 
    Gorrell, S. E.; Nolan, Sean P.R.; Botros, Barbara Brenda; Tan, Choon S; Adamczyk, John J; Greitzer, Edward M (ASME International, 2010-10)
    The effect on rotor work of the phase of an upstream wake relative to the rotor is examined computationally and analytically for a transonic blade row. There can be an important impact on the time-mean performance when the ...
  • Effects of vacancy-solute clusters on diffusivity in metastable Fe-C alloys 
    Van Vliet, Krystyn J.; Kabir, Mohammad Mukul; Lau, Timothy T.; Lin, Xi; Yip, Sidney (American Physical Society, 2010-10)
    Diffusivity in defected crystals depends strongly on the interactions among vacancies and interstitials. Here we present atomistic analyses of point-defect cluster (PDC) concentrations and their kinetic barriers to diffusion ...
  • THE EFFECTS OF VARYING COSMOLOGICAL PARAMETERS ON HALO SUBSTRUCTURE 
    Zukin, Phillip; Vogelsberger, Mark; Hernquist, L.; Dooley, Gregory Alan; Griffen, Brendan Francis; Ji, Alexander Pung; Frebel, Anna L. (IOP Publishing, 2014-05)
    We investigate how different cosmological parameters, such as those delivered by the WMAP and Planck missions, affect the nature and evolution of the dark matter halo substructure. We use a series of flat Λ cold dark matter ...
  • Efficacy of a Device to Narrow the Coronary Sinus in Refractory Angina 
    Verheye, Stefan; Jolicœur, E. Marc; Behan, Miles W.; Pettersson, Thomas; Sainsbury, Paul; Hill, Jonathan; Vrolix, Mathias; Agostoni, Pierfrancesco; Engstrom, Thomas; Labinaz, Marino; de Silva, Ranil; Schwartz, Marc; Meyten, Nathalie; Uren, Neal G.; Doucet, Serge; Tanguay, Jean-François; Lindsay, Steven; Henry, Timothy D.; White, Christopher J.; Edelman, Elazer R.; Banai, Shmuel (New England Journal of Medicine Group, 2015-02)
    Background: Many patients with coronary artery disease who are not candidates for revascularization have refractory angina despite standard medical therapy. The balloon-expandable, stainless steel, hourglass-shaped, ...
  • The Efficacy of an Immunoisolating Membrane System for Islet Xenotransplantation in Minipigs 
    Neufeld, Tova; Ludwig, Barbara; Barkai, Uriel; Weir, Gordon C.; Colton, Clark K.; Evron, Yoav; Balyura, Maria; Yavriyants, Karina; Zimermann, Baruch; Azarov, Dmitri; Maimon, Shiri; Shabtay, Noa; Rozenshtein, Tania; Lorber, Dana; Steffen, Anja; Willenz, Udi; Bloch, Konstantin; Vardi, Pnina; Taube, Ran; de Vos, Paul; Lewis, Eli C.; Bornstein, Stefan R.; Rotem, Avi (Public Library of Science, 2013-08)
    Developing a device that protects xenogeneic islets to allow treatment and potentially cure of diabetes in large mammals has been a major challenge in the past decade. Using xenogeneic islets for transplantation is required ...
  • Efficacy of a Web-Based, Crowdsourced Peer-To-Peer Cognitive Reappraisal Platform for Depression: Randomized Controlled Trial 
    Schueller, Stephen M; Picard, Rosalind W.; Morris, Robert Randall (Gunther Eysenbach, JMIR, 2015-03)
    Background: Self-guided, Web-based interventions for depression show promising results but suffer from high attrition and low user engagement. Online peer support networks can be highly engaging, but they show mixed results ...
  • Efficacy of common surgical compounds in preventing articular chondrocyte death from desiccation 
    Von Keudell, A.; Syed, H. M.; Gomoll, A. H.; Canseco, Jose A. (Springer Berlin Heidelberg, 2013-09)
    Purpose: Purpose of this study was to identify potential substances that prevent desiccation of chondrocytes. Methods: Macroscopically normal bovine cartilage explants (n = 80) were exposed to room air, or covered with ...
  • Efficacy of local neem extracts for sustainable malaria vector control in an African village 
    Bomblies, Arne; Dafalla, Mustafa; Issa-Arzika, Ibrahim; Duchemin, Jean-Bernard; Gianotti, Rebecca Louise; Eltahir, Elfatih A. B. (BioMed Central Ltd, 2008-07)
    Background: Larval control of malaria vectors has been historically successful in reducing malaria transmission, but largely fell out of favour with the introduction of synthetic insecticides and bed nets. However, an ...
  • Efficacy of Sunitinib and Radiotherapy in Genetically Engineered Mouse Model of Soft-Tissue Sarcoma 
    Yoon, Sam S.; Stangenberg, Lars; Lee, Yoon-Jin; Rothrock, Courtney; Dreyfuss, Jonathan M.; Baek, Kwan-Hyuck; Waterman, Peter R.; Nielsen, G. Petur; Weissleder, Ralph; Mahmood, Umar; Park, Peter J.; Dodd, Rebecca D.; Fisher, Carolyn J.; Ryeom, Sandra; Kirsch, David G.; Jacks, Tyler E. (Elsevier, 2009-06)
    Purpose Sunitinib (SU) is a multitargeted receptor tyrosine kinase inhibitor of the vascular endothelial growth factor and platelet-derived growth factor receptors. The present study examined SU and radiotherapy (RT) in ...
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