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Browsing MIT Open Access Articles by Title

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  • Narang, Yashraj S.; Arelekatti, Venkata N M; Winter, Amos G. (ASME International, 2016-11)
    Our research aims to design low-cost, high-performance, passive prosthetic knees for developing countries. In this study, we determine optimal stiffness, damping, and engagement parameters for a low-cost, passive prosthetic ...
  • Li, Yaning; Waas, Anthony M.; Arruda, Ellen M. (Elsevier B.V., 2011-03)
    A synergistic stiffening effect observed in the elastic mechanical properties of LBL assembled polymer/clay nanocomposites is studied via two continuum mechanics approaches. The nanostructure of the representative volume ...
  • Lucas, Timothy Ryan; Forsström, Antti; Saukkonen, Tapio; Ballinger, Ronald G.; Hänninen, Hannu (Springer US, 2016-06)
    Thermal aging and consequent embrittlement of materials are ongoing issues in cast stainless steels, as well as duplex, and high-Cr ferritic stainless steels. Spinodal decomposition is largely responsible for the well-known ...
  • Marino, Fabio Alessio; Faralli, Nicolas; Palacios, Tomas; Ferry, David K.; Goodnick, Stephan M.; Saraniti, Marco (Institute of Electrical and Electronics Engineers, 2009-12)
    This brief aims to show the effects of threading edge dislocations on the dc and RF performance of GaN highelectron mobility transistor (HEMT) devices. A state-of-the-art high-frequency and high-power HEMT was investigated ...
  • Kosmrlj, Andrej; Read, Elizabeth L.; Qi, Ying; Allen, Todd M.; Altfeld, Marcus; Deeks, Steven G.; Pereyra, Florencia; Carrington, Mary; Walker, Bruce D.; Chakraborty, Arup K. (Nature Publishing Group, 2010-05)
    Without therapy, most people infected with human immunodeficiency virus (HIV) ultimately progress to AIDS. Rare individuals (‘elite controllers’) maintain very low levels of HIV RNA without therapy, thereby making disease ...
  • Cummings, M. L.; Boussemart, Yves; Donmez, Birsen; Las Fargeas, Jonathan C. (Curran Associates, Inc., 2009-04)
    This paper describes the results of an experiment designed to examine the effects of time pressure on behavioral patterns. The main research hypothesis is that people under time pressure tend to increasingly rely on ...
  • Imakaev, Maksim Viktorovich; Tchourine, Konstantin M.; Nechaev, Sergei K.; Mirny, Leonid A. (Royal Society of Chemistry, 2015-01)
    Topological constraints can affect both equilibrium and dynamic properties of polymer systems and can play a role in the organization of chromosomes. Despite many theoretical studies, the effects of topological constraints ...
  • Butscher, Christoph; Einstein, Herbert H.; Huggenberger, Peter (American Geophysical Union (AGU), 2011-11)
    [1] Swelling of clay-sulfate rocks is a major threat in tunneling. It is triggered by the transformation of the sulfate mineral anhydrite into gypsum as a result of water inflow in anhydrite-containing layers after tunnel ...
  • Seto, Jennifer E.; Polat, Baris E.; Blankschtein, Daniel; Langer, Robert; Lopez, Renata F. V. (Elsevier, 2010-03)
    The simultaneous application of ultrasound and the surfactant sodium lauryl sulfate (referred to as US/SLS) to skin enhances transdermal drug delivery (TDD) in a synergistic mechanical and chemical manner. Since full-thickness ...
  • Khanna, Ira; Roy, Anindo; Rodgers, Mary M.; Krebs, Hermano Igo; Macko, Richard M.; Forrester, Larry W. (BioMed Central Ltd, 2010-05)
    Background Hemiparesis after stroke often leads to impaired ankle motor control that impacts gait function. In recent studies, robotic devices have been developed to address this impairment. While capable of imparting ...
  • Khanna, Ira; Roy, Anindo; Krebs, Hermano Igo; Rodger, Mary M.; Macko, Richard M.; Forrester, Larry W. (BioMed Central Ltd, 2010-05)
    Background Hemiparesis after stroke often leads to impaired ankle motor control that impacts gait function. In recent studies, robotic devices have been developed to address this impairment. While capable of imparting ...
  • Gorrell, S. E.; Nolan, Sean P.R.; Botros, Barbara Brenda; Tan, Choon S; Adamczyk, John J; Greitzer, Edward M (ASME International, 2010-10)
    The effect on rotor work of the phase of an upstream wake relative to the rotor is examined computationally and analytically for a transonic blade row. There can be an important impact on the time-mean performance when the ...
  • Van Vliet, Krystyn J.; Kabir, Mohammad Mukul; Lau, Timothy T.; Lin, Xi; Yip, Sidney (American Physical Society, 2010-10)
    Diffusivity in defected crystals depends strongly on the interactions among vacancies and interstitials. Here we present atomistic analyses of point-defect cluster (PDC) concentrations and their kinetic barriers to diffusion ...
  • Zukin, Phillip; Vogelsberger, Mark; Hernquist, L.; Dooley, Gregory Alan; Griffen, Brendan Francis; Ji, Alexander Pung; Frebel, Anna L. (IOP Publishing, 2014-05)
    We investigate how different cosmological parameters, such as those delivered by the WMAP and Planck missions, affect the nature and evolution of the dark matter halo substructure. We use a series of flat Λ cold dark matter ...
  • Verheye, Stefan; Jolicœur, E. Marc; Behan, Miles W.; Pettersson, Thomas; Sainsbury, Paul; Hill, Jonathan; Vrolix, Mathias; Agostoni, Pierfrancesco; Engstrom, Thomas; Labinaz, Marino; de Silva, Ranil; Schwartz, Marc; Meyten, Nathalie; Uren, Neal G.; Doucet, Serge; Tanguay, Jean-François; Lindsay, Steven; Henry, Timothy D.; White, Christopher J.; Edelman, Elazer R.; Banai, Shmuel (New England Journal of Medicine Group, 2015-02)
    Background: Many patients with coronary artery disease who are not candidates for revascularization have refractory angina despite standard medical therapy. The balloon-expandable, stainless steel, hourglass-shaped, ...
  • Neufeld, Tova; Ludwig, Barbara; Barkai, Uriel; Weir, Gordon C.; Colton, Clark K.; Evron, Yoav; Balyura, Maria; Yavriyants, Karina; Zimermann, Baruch; Azarov, Dmitri; Maimon, Shiri; Shabtay, Noa; Rozenshtein, Tania; Lorber, Dana; Steffen, Anja; Willenz, Udi; Bloch, Konstantin; Vardi, Pnina; Taube, Ran; de Vos, Paul; Lewis, Eli C.; Bornstein, Stefan R.; Rotem, Avi (Public Library of Science, 2013-08)
    Developing a device that protects xenogeneic islets to allow treatment and potentially cure of diabetes in large mammals has been a major challenge in the past decade. Using xenogeneic islets for transplantation is required ...
  • Schueller, Stephen M; Picard, Rosalind W.; Morris, Robert Randall (Gunther Eysenbach, JMIR, 2015-03)
    Background: Self-guided, Web-based interventions for depression show promising results but suffer from high attrition and low user engagement. Online peer support networks can be highly engaging, but they show mixed results ...
  • Von Keudell, A.; Syed, H. M.; Gomoll, A. H.; Canseco, Jose A. (Springer Berlin Heidelberg, 2013-09)
    Purpose: Purpose of this study was to identify potential substances that prevent desiccation of chondrocytes. Methods: Macroscopically normal bovine cartilage explants (n = 80) were exposed to room air, or covered with ...
  • Bomblies, Arne; Dafalla, Mustafa; Issa-Arzika, Ibrahim; Duchemin, Jean-Bernard; Gianotti, Rebecca Louise; Eltahir, Elfatih A. B. (BioMed Central Ltd, 2008-07)
    Background: Larval control of malaria vectors has been historically successful in reducing malaria transmission, but largely fell out of favour with the introduction of synthetic insecticides and bed nets. However, an ...
  • Yoon, Sam S.; Stangenberg, Lars; Lee, Yoon-Jin; Rothrock, Courtney; Dreyfuss, Jonathan M.; Baek, Kwan-Hyuck; Waterman, Peter R.; Nielsen, G. Petur; Weissleder, Ralph; Mahmood, Umar; Park, Peter J.; Dodd, Rebecca D.; Fisher, Carolyn J.; Ryeom, Sandra; Kirsch, David G.; Jacks, Tyler E. (Elsevier, 2009-06)
    Purpose Sunitinib (SU) is a multitargeted receptor tyrosine kinase inhibitor of the vascular endothelial growth factor and platelet-derived growth factor receptors. The present study examined SU and radiotherapy (RT) in ...
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