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Browsing MIT Open Access Articles by Title

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  • Ng, Shengyong; Velmurugan, Soundarapandian; Galstian, Ani; Shan, Jing; Logan, David J.; Carpenter, Anne E.; Thomas, David; Sim, B. Kim Lee; Mota, Maria M.; Hoffman, Stephen L.; Bhatia, Sangeeta N.; March-Riera, Sandra; Bhatia, Sangeeta N. (Elsevier, 2013-07)
    The Plasmodium liver stage is an attractive target for the development of antimalarial drugs and vaccines, as it provides an opportunity to interrupt the life cycle of the parasite at a critical early stage. However, ...
  • Sabatini, David M.; Wood, Kris C.; Konieczkowski, David J.; Johannessen, Cory M.; Boehm, Jesse S.; Tamayo, Pablo; Botvinnik, Olga B.; Mesirov, Jill P.; Hahn, William C.; Root, David E.; Garraway, Levi A. (American Association for the Advancement of Science (AAAS), 2012-05)
    Cell microarrays are a promising tool for performing large-scale functional genomic screening in mammalian cells at reasonable cost, but owing to technical limitations they have been restricted for use with a narrow range ...
  • Selimović, Šeila; Oh, Jonghyun; Bae, Hojae; Dokmeci, Mehmet; Khademhosseini, Ali (MDPI AG, 2012-09)
    Hydrogels in which cells are encapsulated are of great potential interest for tissue engineering applications. These gels provide a structure inside which cells can spread and proliferate. Such structures benefit from ...
  • Paparcone, Raffaella; Buehler, Markus J. (American Institute of Physics (AIP), 2009-06)
    Amyloid fibril formation and characterization are crucial due to their association with severe degenerative disorders such as Alzheimer’s, type II diabetes, and Parkinson’s disease. Here we present an atomistic-based ...
  • Khademhosseini, Ali; Chung, Bong Geun (Institute of Electrical and Electronics Engineers, 2009-05)
    Microscale technologies are emerging as enabling tools for tissue engineering and biology. Here, we present our experience in developing microscale technologies to regulate cell-microenvironment interactions and generate ...
  • Shiga, Takuma; Shiomi, Junichiro; Ma, Jie; Delaire, Olivier; Radzynski, Tomasz; Lusakowski, Andrzej; Esfarjani, Keivan; Chen, Gang (American Physical Society, 2012-04)
    The microscopic physics behind low-lattice thermal conductivity of single-crystal rock salt lead telluride (PbTe) is investigated. Mode-dependent phonon (normal and umklapp) scattering rates and their impact on thermal ...
  • Regnault, N.; Todadri, Senthil (American Physical Society, 2013-10)
    In two dimensions strongly interacting bosons in a magnetic field can form an integer quantum Hall state. This state has a bulk gap, no fractional charges or topological order in the bulk, but nevertheless quantized Hall ...
  • Safavi-Naini, Arghavan; Rabl, P.; Weck, P. F.; Sadeghpour, H. R. (American Physical Society, 2011-08)
    Motional heating of ions in microfabricated traps is one of the open challenges hindering experimental realizations of large-scale quantum processing devices. Recently, a series of measurements of the heating rates in ...
  • Gerber, U.; Hofmann, C. P.; Kampfer, Florian; Wiese, U. J. (American Physical Society, 2010-02)
    We consider a microscopic model for a doped quantum ferromagnet as a test case for the systematic low-energy effective field theory for magnons and holes, which is constructed in complete analogy to the case of quantum ...
  • Iusan, Diana; Kabir, Mohammad Mukul; Granas, Oscar; Eriksson, Olle; Sanyal, Biplab (American Physical Society, 2009-03)
    Density functional theory was applied to study the chemical and magnetic interactions between Co atoms doped in ZnO. It was found that the Co impurities tend to form nanoclusters and the interactions between these atoms ...
  • Cho, Woo-Kyung; Ankrum, James Allen; Guo, Dagang; Chester, Shawn A.; Yang, Seung Yun; Kashyap, Anurag; Campbell, Georgina A.; Wood, Robert J.; Rijal, Ram K.; Karnik, Rohit N.; Langer, Robert; Karp, Jeffrey Michael (National Academy of Sciences (U.S.), 2012-12)
    North American porcupines are well known for their specialized hairs, or quills that feature microscopic backward-facing deployable barbs that are used in self-defense. Herein we show that the natural quill’s geometry ...
  • Johnson, Steven G.; Joannopoulos, John D.; McCauley, Alexander Patrick; Rodriguez, Alejandro W.; Reid, M. T. Homer; Zhao, Rongkuo; Zhou, Jiangfeng; Rossa, F. S. S.; Dalvit, D. A. R.; Soukoulis, Costas M. (American Physical Society, 2010-10)
    We examine a recent prediction for the chirality dependence of the Casimir force in chiral metamaterials by numerical computation of the forces between the exact microstructures, rather than homogeneous approximations. ...
  • Singh, Karuna; Tsai, Li-Huei (Elsevier, 2010-01)
    The microtubule network is crucial for the developing nervous system and mutations in tubulin-encoding genes disrupt neuronal migration. In this issue, Tischfield et al. (2010) report that mutations in the neuronal TUBB3 ...
  • Welburn, Julie P. I.; Cheeseman, Iain McPherson (American Society for Cell Biology, 2012-10)
    Microtubule dynamics are essential throughout mitosis to ensure correct chromosome segregation. Microtubule depolymerization is controlled in part by microtubule depolymerases, including the kinesin-13 family of proteins. ...
  • Hohnloser, Stefan H.; Cohen, Richard J. (Elsevier B.V., 2012-10)
    Gupta et al1 present a meta-analysis and conclude that microvolt T-wave alternans testing (MTWA) does not modify risk of sudden cardiac death (SCD) sufficiently for clinical use. Their analysis involves a number of ...
  • Cohen, Richard J.; Hohnloser, Stefan H. (Oxford University Press, 2012-05)
    Jackson et al. reported on a cohort of heart failure patients and concluded that microvolt T-wave alternans (MTWA) testing has limited utility in this population. Of note, this assessment was made in the complete absence ...
  • Drewsen, M; Shi, Molu; Herskind, Peter F.; Chuang, Isaac L. (IOP Publishing, 2013-11)
    A general method for rotational microwave spectroscopy and control of polar molecular ions via direct microwave addressing is considered. Our method makes use of spatially varying ac Stark shifts, induced by far off-resonant, ...
  • Khademhosseini, Ali; Hwang, Yu-Shik; Chung, Bong Geun; Moeller, Hannes-Christian; Ortmann, Daniel; Hattori, Nobuaki (National Academy of Sciences (U.S.), 2009-09)
    Recently, various approaches for controlling the embryonic stem (ES) cell microenvironment have been developed for regulating cellular fate decisions. It has been reported that the lineage specific differentiation could ...
  • Ozaydin-Ince, Gozde; Dubach, J. Matthew; Gleason, Karen K.; Clark, Heather A. (National Academy of Sciences, 2011-02)
    There have been a variety of nanoparticles created for in vivo uses ranging from gene and drug delivery to tumor imaging and physiological monitoring. The use of nanoparticles to measure physiological conditions while being ...
  • Huang, E-Wen; Qiao, Junwei; Winiarski, Bartlomiej; Lee, Wen-Jay; Scheel, Mario; Chuang, Chih-Pin; Liaw, Peter K.; Lo, Yu-Chieh; Zhang, Yong; Di Michiel, Marco (Nature Publishing Group, 2014-03)
    In-situ synchrotron x-ray experiments have been used to follow the evolution of the diffraction peaks for crystalline dendrites embedded in a bulk metallic glass matrix subjected to a compressive loading-unloading cycle. ...
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