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Browsing MIT Open Access Articles by Title

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  • Sydor, Andrew M.; Jost, Marco; Ryan, Katherine S.; Turo, Kaitlyn E.; Douglas, Colin D.; Drennan, Catherine L.; Zamble, Deborah B. (American Chemical Society (ACS), 2013-02)
    GTPases are critical molecular switches involved in a wide range of biological functions. Recent phylogenetic and genomic analyses of the large, mostly uncharacterized COG0523 subfamily of GTPases revealed a link between ...
  • Stubbe, JoAnne; Cotruvo, Joseph A., Jr.; Cotruvo, Jr, Joseph A. (Royal Society of Chemistry, The, 2012-08)
    How cells ensure correct metallation of a given protein and whether a degree of promiscuity in metal binding has evolved are largely unanswered questions. In a classic case, iron- and manganese-dependent superoxide dismutases ...
  • Bermejo-Deval, Ricardo; Assary, Rajeev S.; Nikolla, Eranda; Moliner, Manuel; Roman-Leshkov, Yuriy; Hwang, Son-Jong; Palsdotter, Arna; Silverman, Dorothy; Lobo, Raul F.; Curtiss, Larry A.; Davis, Mark E. (National Academy of Sciences (U.S.), 2012-06)
    Isomerization of sugars is used in a variety of industrially relevant processes and in glycolysis. Here, we show that hydrophobic zeolite beta with framework tin or titanium Lewis acid centers isomerizes sugars, e.g., ...
  • Placco, Vinicius M.; Beers, Timothy C.; Karakas, Amanda I.; Kennedy, Catherine R.; Rossi, Silvia; Christlieb, Norbert; Stancliffe, Richard J.; Frebel, Anna L. (IOP Publishing, 2013-05)
    We present a comprehensive abundance analysis of two newly discovered carbon-enhanced metal-poor (CEMP) stars. HE 2138?3336 is a s-process-rich star with [Fe/H] = -2.79, and has the highest [Pb/Fe] abundance ratio measured ...
  • Placco, Vinicius M.; Beers, Timothy C.; Christlieb, Norbert; Lee, Young Sun; Kennedy, Catherine R.; Rossi, Silvia; Santucci, Rafael M.; Frebel, Anna L. (IOP Publishing, 2014-01)
    We report on the discovery of seven low-metallicity stars selected from the Hamburg/ESO Survey, six of which are extremely metal-poor (EMP, [Fe/H] ≤ –3.0), with four having [Fe/H] ≤ –3.5. Chemical abundances or upper limits ...
  • Lelyveld, Victor S.; Brustad, Eric; Arnold, Frances H.; Jasanoff, Alan Pradip (American Chemical Society, 2011-02)
    Engineered metalloproteins constitute a flexible new class of analyte-sensitive molecular imaging agents detectable by magnetic resonance imaging (MRI), but their contrast effects are generally weaker than synthetic agents. ...
  • Hwang, Harold Young; Liu, M.; Fan, K.; Zhang, J.; Strikwerda, A. C.; Sternbach, A.; Brandt, N. C.; Perkins Jr, Bradford G.; Zhang, X.; Averitt, R. D.; Nelson, Keith Adam (EDP Sciences, 2013-03)
    We demonstrate large nonlinear terahertz responses in the gaps of metamaterial split ring resonators in several materials and use nonlinear THz transmission and THz-pump/THz-probe spectroscopy to study the nonlinear responses ...
  • Chindelevitch, Leonid; Stanley, Sarah; Hung, Deborah; Regev, Aviv; Berger, Bonnie (Springer/BioMed Central Ltd, 2012-01)
    Reconstructed models of metabolic networks are widely used for studying metabolism in various organisms. Many different reconstructions of the same organism often exist concurrently, forcing researchers to choose one of ...
  • Paradiso, Joseph A.; Lifton, Joshua; Laibowitz, Mathew Joel; Harry, Drew Erikson; Gong, Nan-wei; Mittal, Manas (Institute of Electrical and Electronics Engineers, 2009-07)
    Looks at how MIT Media Lab's Responsive Environments Group is exploring ways to bridge networked electronic sensors and human perception through "cross reality" implementations that render and manifest phenomena between ...
  • Neuman, Yair; Assaf, Dan; Cohen, Yohai; Last, Mark; Argamon, Shlomo; Howard, Newton; Frieder, Ophir (Public Library of Science, 2013-04)
    Identifying metaphorical language-use (e.g., sweet child) is one of the challenges facing natural language processing. This paper describes three novel algorithms for automatic metaphor identification. The algorithms are ...
  • Massachusetts Institute of Technology. Department of Mathematics; Brubaker, Benjamin Brock; Brubaker, Benjamin Brock (Birkhauser Boston, 2012)
    We study spherical Whittaker functions on a metaplectic cover of GL(r + 1) over a nonarchimedean local eld using lattice models from statistical mechanics. An explicit description of this Whittaker function was given ...
  • Hanna, Jacob; Markoulaki, Styliani; Mitalipova, Maisam; Cheng, Albert W.; Cassady, John P.; Staerk, Judith; Carey, Bryce W.; Lengner, Christopher J.; Foreman, Ruth K.; Love, Jennifer; Gao, Qing; Kim, Jongpil; Jaenisch, Rudolf (Elsevier, 2009-05)
    Embryonic stem (ES) cells are isolated from the inner cell mass (ICM) of blastocysts, whereas epiblast stem cells (EpiSCs) are derived from the post-implantation epiblast and display a restricted developmental potential. ...
  • Soto, R.; Martinez, M. N.; Baibich, M. N.; Florez Uribe, Juan Manuel; Vargas, P. (American Physical Society, 2009-05)
    It is well known that the spin-chain compound Ca[subscript 3]Co[subscript 2]O[subscript 6] exhibits interesting plateaus in the magnetization as a function of the magnetic field at low temperatures. The origin of them is ...
  • Kerman, Andrew J. (American Physical Society, 2010-01)
    We propose a superconducting qubit design, based on a tunable rf SQUID and nanowire kinetic inductors, which has a dramatically reduced transverse electromagnetic coupling to its environment, so that its excited state ...
  • Byl, Katie; Tedrake, Russell Louis (Sage, 2009-06)
    Legged robots that operate in the real world are inherently subject to stochasticity in their dynamics and uncertainty about the terrain. Owing to limited energy budgets and limited control authority, these “disturbances” ...
  • Valastyan, Scott; Weinberg, Robert A. (Springer (Biomed Central Ltd.), 2010-11)
    Recent studies have implicated the microRNA biogenesis enzyme Dicer as a suppressor of breast carcinoma metastasis and elucidated upstream signaling pathways that control Dicer levels.
  • Hynes, Richard O.; Hynes, Richard O. (Elsevier, 2011-12)
    Two recent papers in Cancer Cell (Lu et al., this issue of Cancer Cell, and Kang et al.) illustrate means whereby acquisition of VCAM-1 by tumor cells can promote metastasis. First, monocyte/macrophages expressing α4 ...
  • Ottesen, Elizabeth; Marin, Roman, III; Preston, Christina M.; Young, Curtis Robert, III; Ryan, John P.; Scholin, Christopher A.; DeLong, Edward (Nature Publishing Group, 2011-06)
    Planktonic microbial activity and community structure is dynamic, and can change dramatically on time scales of hours to days. Yet for logistical reasons, this temporal scale is typically under-sampled in the marine ...
  • Ventouras, Laure-Anne; Wilson, Samuel T.; Karl, David M.; Martinez, Asuncion; DeLong, Edward (Frontiers Research Foundation, 2013-11)
    Aerobic degradation of methylphosphonate (MPn) by marine bacterioplankton has been hypothesized to contribute significantly to the ocean's methane supersaturation, yet little is known about MPn utilization by marine microbes. ...
  • Mickley, Loretta J.; Jacob, Daniel J.; Leibensperger, Eric Michael; Zhang, L.; Fisher, J.A.; Pye, Havala Olson Taylor; Tai, Amos P.K. (Copernicus GmbH, 2012-03)
    We applied a multiple linear regression model to understand the relationships of PM[subscript 2.5] with meteorological variables in the contiguous US and from there to infer the sensitivity of PM[subscript 2.5] to climate ...
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