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Browsing MIT Open Access Articles by Title

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  • Brennan, Thomas J.; Lo, Andrew W. (Institute for Operations Research and the Management Sciences, 2010-06)
    A key result of the capital asset pricing model (CAPM) is that the market portfolio—the portfolio of all assets in which each asset's weight is proportional to its total market capitalization—lies on the mean-variance-efficient ...
  • Yunes, Nicolas; Kocsis, Bence; Loeb, Abraham; Haiman, Zoltan (American Physical Society (APS), 2011-10)
    We study the effects of a thin gaseous accretion disk on the inspiral of a stellar-mass black hole into a supermassive black hole. We construct a phenomenological angular momentum transport equation that reproduces known ...
  • Orlin, James B. (Association for Computing Machinery, 2010-06)
    We give the first strongly polynomial time algorithm for computing an equilibrium for the linear utilities case of Fisher's market model. We consider a problem with a set B of buyers and a set G of divisible goods. Each ...
  • Cheung, Wang Chi; Goemans, Michel X.; Wong, Sam Chiu-Wai (Society for Industrial and Applied Mathematics, 2014-01)
    In this paper, we consider the minimum unweighted Vertex Cover problem with Hard Capacity constraints (VCHC) on multigraphs and hypergraphs. Given a graph, the objective of VCHC is to find a smallest multiset of vertices ...
  • Ohlson, Tomas; Aggarwal, Varun; Elofsson, Arne; MacCallum, Robert M. (BioMed Central Ltd, 2006-07)
    Background Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic trees and protein structure prediction. ...
  • Manurangsi, Pasin; Moshkovitz, Dana (Springer-Verlag, 2013)
    The projection games (aka Label-Cover) problem is of great importance to the field of approximation algorithms, since most of the NP-hardness of approximation results we know today are reductions from Label-Cover. In this ...
  • Ahn, Jooeun; Hogan, Neville (Public Library of Science, 2015-03)
    Mathematical techniques have provided tools to quantify the stability of rhythmic movements of humans and machines as well as mathematical models. One archetypal example is the use of Floquet multipliers: assuming periodic ...
  • Wong, Liang Jie; Johnson, Steven G.; Kaertner, Franz X. (Optical Society of America, 2014-02)
    We derive an asymptotically accurate formula for the beam waist of ultrashort, tightly focused fundamental linearly polarized, radially polarized, and azimuthally polarized modes in free space. We compute the exact beam ...
  • Hoeppner, Marc P.; Lundquist, Andrew; Pirun, Mono; Meadows, Jennifer R. S.; Zamani, Neda; Johnson, Jeremy; Sundstrom, Gorel; Cook, April; FitzGerald, Michael G.; Swofford, Ross; Mauceli, Evan; Moghadam, Behrooz Torabi; Greka, Anna; Alfoldi, Jessica; Abouelleil, Amr; Aftuck, Lynne; Bessette, Daniel; Berlin, Aaron M.; Brown, Adam; Gearin, Gary; Lui, Annie; Macdonald, J. Pendexter; Priest, Margaret; Shea, Terrance; Turner-Maier, Jason; Zimmer, Andrew; Lander, Eric S.; di Palma, Federica; Lindblad-Toh, Kerstin; Grabherr, Manfred G. (Public Library of Science, 2014-03)
    The domestic dog, Canis familiaris, is a well-established model system for mapping trait and disease loci. While the original draft sequence was of good quality, gaps were abundant particularly in promoter regions of the ...
  • Ma, Xiaohua; Hautier, Geoffroy; Jain, Anubhav; Doe, Robert E.; Ceder, Gerbrand (Electrochemical Society, 2012-12)
    We present a layered Li-intercalation oxide that operates on the V[superscript 3+]/V[superscript 4+] redox couple. The stabilization effect of adding a +3 element into the layered LiVO[subscript 2] has been studied by first ...
  • Lee, Hong Geun; Buchwald, Stephen Leffler; Milner, Phillip John (American Chemical Society (ACS), 2013-11)
    The stable Pd(0) species [(1,5-cyclooctadiene)(L·Pd)[subscript 2]] (L = AdBrettPhos) has been prepared and successfully evaluated as a precatalyst for the fluorination of aryl triflates derived from biologically active and ...
  • Naeser, Margaret A.; Saltmarche, Anita; Krengel, Maxine H.; Hamblin, Michael R.; Knight, Jeffrey A. (Mary Ann Liebert, Inc., 2011-05)
    Objective: Two chronic, traumatic brain injury (TBI) cases, where cognition improved following treatment with red and near-infrared light-emitting diodes (LEDs), applied transcranially to forehead and scalp areas, are ...
  • Boyce, J. W.; Hodges, Kip Vernon; King, D.; Crowley, J. L.; Jercinovic, M.; Chatterjee, Nilanjan; Bowring, Samuel A.; Searle, M. (American Geophysical Union (AGU), 2009-09)
    The newly developed laser microprobe (U-Th)/He thermochronometer permits, for the first time, the ability to generate precise (U-Th)/He cooling ages for even very young (<1 Ma) samples with a spatial resolution on the order ...
  • McMurry, Andrew J; Fitch, Britt; Savova, Guergana; Reis, Ben Y; Kohane, Isaac (BioMed Central Ltd, 2013-10)
    Background: Physician notes routinely recorded during patient care represent a vast and underutilized resource for human disease studies on a population scale. Their use in research is primarily limited by the need to ...
  • Yang, Yung-Hun; Brigham, Christopher J.; Willis, Laura B.; Rha, ChoKyun; Sinskey, Anthony J. (Springer, 2011-01)
    Extracting polyhydroxyalkanoate (PHA) polymer from bacterial cells often involves harsh conditions, including use of environmentally harmful solvents. We evaluated different detergents under various conditions to extract ...
  • Orosz, Jerome A.; Steiner, James F.; McClintock, Jeffrey E.; Torres, Manuel A. P.; Bailyn, Charles D.; Miller, Jon M.; Remillard, Ronald Alan (IOP Publishing, 2011-03)
    We present an improved dynamical model of the X-ray binary and microquasar XTE J1550–564 based on new moderate-resolution optical spectroscopy and near-infrared photometry obtained with the 6.5 m Magellan Telescopes at Las ...
  • Urban, Karsten; Patera, Anthony T. (American Mathematical Society (AMS), 2013-10)
    We consider a space-time variational formulation for linear parabolic partial differential equations. We introduce an associated Petrov-Galerkin truth finite element discretization with favorable discrete inf-sup constant ...
  • Tsakraklides, Vasiliki; Brevnova, Elena; Shaw, A. Joe; Stephanopoulos, Gregory (Public Library of Science, 2015-07)
    Gene targeting is a challenge in organisms where non-homologous end-joining is the predominant form of recombination. We show that cell division cycle synchronization can be applied to significantly increase the rate of ...
  • Bansal, Mukul S.; Wu, Yi-Chieh; Alm, Eric J.; Kellis, Manolis (Oxford University Press, 2014-12)
    Motivation: The accurate inference of gene trees is a necessary step in many evolutionary studies. Although the problem of accurate gene tree inference has received considerable attention, most existing methods are only ...
  • Kurosawa, Kazuhiko; Radek, Andreas; Plassmeier, Jens K.; Sinskey, Anthony J. (Biomed Central Ltd., 2015-02)
    Background: Glycerol generated during renewable fuel production processes is potentially an attractive substrate for the production of value-added materials by fermentation. An engineered strain MITXM-61 of the oleaginous ...
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