Browsing MIT Open Access Articles by Title
Now showing items 7089-7108 of 55750
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Combining the specific anti-MUC1 antibody TAB004 and LIP-MSA-IL-2 limits pancreatic cancer progression in immune competent murine models of pancreatic ductal adenocarcinoma
(Frontiers Media SA, 2019-04)This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the ... -
Combining time-resolved optical (TOS), electronic (trARPES) and structural (UED) probes on the class of rare earth tritellurides RTe₃
(EDP Sciences, 2019-04)The combination of EUV based time-resolved Angle-Resolved-Photo-Electron-Spectroscopy (trARPES), Ultrafast-Electron-Diffraction (UED) and Transient-Optical-Spectroscopy (TOS) facilitates a comprehensive study and all-embracing ... -
Combining Two Consistent Estimators
(Emerald (MCB UP), 2012)This chapter shows how a weighted average of a forward and reverse Jackknife IV estimator (JIVE) yields estimators that are robust against heteroscedasticity and many instruments. These estimators, called HFUL (Heteroscedasticity ... -
Combining video games and constructionist design to support deep learning in play
(International Society of the Learning Sciences, 2014-06)This effort has produced many interesting games though it is unclear if “educational video games” have achieved their promise. Similarly, for many years constructionists have engaged children in learning across a variety ... -
COMBREX: a project to accelerate the functional annotation of prokaryotic genomes
(Oxford University Press (OUP), 2010-11)COMBREX (http://combrex.bu.edu) is a project to increase the speed of the functional annotation of new bacterial and archaeal genomes. It consists of a database of functional predictions produced by computational biologists ... -
Combustion of Synthetic Jet Fuel: Chemical Kinetic Modeling and Uncertainty Analysis
(American Institute of Aeronautics and Astronautics (AIAA), 2016-08)Reaction mechanisms for jet-fuel combustion were built with the aim of providing a better description of the chemistry to reacting flow simulations used to design future aircraft engines. This research effort focused on ... -
COMET: Learning Cardinality Constrained Mixture of Experts with Trees and Local Search
(ACM|Proceedings of the 29th ACM SIGKDD Conference on Knowledge Discovery and Data Mining, 2023-08-06) -
CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage
(Elsevier BV, 2021)Although DNA repair is known to impact susceptibility to cancer and other diseases, relatively few population studies have been performed to evaluate DNA repair kinetics in people due to the difficulty of assessing DNA ... -
CometChip enables parallel analysis of multiple DNA repair activities
(Elsevier BV, 2021-10)DNA damage can be cytotoxic and mutagenic, and it is directly linked to aging, cancer, and other diseases. To counteract the deleterious effects of DNA damage, cells have evolved highly conserved DNA repair pathways. Many ... -
CometChip: A High-throughput 96-Well Platform for Measuring DNA Damage in Microarrayed Human Cells
(MyJoVE Corporation, 2014-10)DNA damaging agents can promote aging, disease and cancer and they are ubiquitous in the environment and produced within human cells as normal cellular metabolites. Ironically, at high doses DNA damaging agents are also ... -
The Comédie-Française by the Numbers, 1752–2020
(PubPub, 2020) -
Coming to See Action as Symbol: the Computer as Collaborator
(Springer International Publishing, 2020-05)Our work with young children began as a project and a place that we called The Laboratory for Making Things. Our hypothesis was that deep learning could accrue in an environment where projects were designed that used ... -
Coming to See Action as Symbol: the Computer as Collaborator
(Springer International Publishing, 2020-05-09)Abstract Our work with young children began as a project and a place that we called The Laboratory for Making Things. Our hypothesis was that deep learning could accrue in an environment where projects were designed that ... -
ComLittee: Literature Discovery with Personal Elected Author Committees
(ACM|Proceedings of the 2023 CHI Conference on Human Factors in Computing Systems, 2023-04-19) -
Command and Control for Multifunction Phased Array Radar
(Institute of Electrical and Electronics Engineers (IEEE), 2017-08)We discuss the challenge of managing the Multifunction Phased Array Radar (MPAR) timeline to satisfy the requirements of its multiple missions, with a particular focus on weather surveillance. This command and control (C2) ... -
Commemorating the 50‐Year Anniversary of Ball and Brown (1968): The Evolution of Capital Market Research over the Past 50 Years
(Wiley, 2019)© University of Chicago on behalf of the Accounting Research Center, 2019 We commemorate the 50th anniversary of Ball and Brown [1968] by chronicling its impact on capital market research in accounting. We trace the evolution ... -
Commensal epitopes drive differentiation of colonic T regs
(American Association for the Advancement of Science (AAAS), 2020)© 2020 The Authors. The gut microbiome is the largest source of intrinsic non-self-antigens that are continuously sensed by the immune system but typically do not elicit lymphocyte responses. CD4+ T cells are critical to ... -
Commensal epitopes drive differentiation of colonic T regs
(American Association for the Advancement of Science (AAAS), 2020-04)© 2020 The Authors. The gut microbiome is the largest source of intrinsic non-self-antigens that are continuously sensed by the immune system but typically do not elicit lymphocyte responses. CD4+ T cells are critical to ... -
The commensal microbiota exacerbate infectious colitis in stressor-exposed mice
(Elsevier BV, 2016-09)Exposure to a prolonged restraint stressor disrupts the colonic microbiota community composition, and is associated with an elevated inflammatory response to colonic pathogen challenge. Since the stability of the microbiota ... -
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells
(Elsevier BV, 2019-02)Lung cancer is closely associated with chronic inflammation, but the causes of inflammation and the specific immune mediators have not been fully elucidated. The lung is a mucosal tissue colonized by a diverse bacterial ...
