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Browsing MIT Open Access Articles by Title

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  • Chiu, C. S.; Ignarra, Christina; Bugel, Leonard G.; Chen, H.; Conrad, Janet; Jones, Benjamin James Poyner; Katori, Teppei; Moult, Ian James (Institute of Physics Publishing, 2012-07)
    The scintillation detection systems of liquid argon time projection chambers (LArTPCs) require wavelength shifters to detect the 128 nm scintillation light produced in liquid argon. Tetraphenyl butadiene (TPB) is a fluorescent ...
  • Brooks, Zanzile; Ulm, Franz-Josef; Einstein, Herbert H. (Springer-Verlag, 2013-03)
    This study explores the interaction between crack initiation and nanomechanical properties in the crack-tip fracture process zone of Carrara marble. Specimens with preexisting cracks were loaded in a uniaxial testing machine ...
  • Acemoglu, Daron; Aghion, Philippe; Bursztyn, Leonardo; Hemous, David (American Economic Association, 2012-02)
    This paper introduces endogenous and directed technical change in a growth model with environmental constraints. A unique final good is produced by combining inputs from two sectors. One of these sectors uses “dirty” ...
  • Cappellaro, Paola; Hodges, Jonathan S.; Goldstein, Garry; Jiang, Liang; Maze, Jeronimo R.; Sørensen, A. S.; Lukin, Mikhail D. (American Physical Society, 2012-03)
    We investigate the sensitivity of a recently proposed method for precision measurement [ Phys. Rev. Lett. 106 140502 (2011)], focusing on an implementation based on solid-state spin systems. The scheme amplifies a quantum ...
  • Goldstein, Garry; Cappellaro, Paola; Maze, Jeronimo R.; Hodges, Jonathan S.; Jiang, L.; Sorensen, A. S.; Lukin, M. D. (American Physical Society, 2011-04)
    We describe a method to enhance the sensitivity of precision measurements that takes advantage of the environment of a quantum sensor to amplify the response of the sensor to weak external perturbations. An individual qubit ...
  • Rebentrost, Patrick; Mohseni, Masoud; Kassal, Ivan; Lloyd, Seth; Aspuru-Guzik, Alan (Institute of Physics Publishing, 2009-03)
    Transport phenomena at the nanoscale are of interest due to the presence of both quantum and classical behavior. In this work, we demonstrate that quantum transport efficiency can be enhanced by a dynamical interplay of ...
  • Volkov, Mikhail; Cornejo Collado, Alex; Lynch, Nancy Ann; Rus, Daniela L. (Springer Berlin / Heidelberg, 2011-11)
    This paper addresses the problem of obtaining a concise description of a physical environment for robotic exploration. We aim to determine the number of robots required to clear an environment using non-recontaminating ...
  • Moon, Tae Seok; Yoon, Sang-Hwal; Tsang Mui Ching, Mary-Jane; Lanza, Amanda M.; Prather, Kristala L. Jones (Elsevier, 2009-05)
    d-Glucuronate is a key metabolite in the process of detoxification of xenobiotics and in a recently constructed synthetic pathway to produce d-glucaric acid, a “top value-added chemical” from biomass. A simple and specific ...
  • Ernst, Robert; Claessen, Jasper H. L.; Mueller, Britta; Sanyal, Sumana; Spooner, Eric; van der Veen, Annemarthe G.; Kirak, Oktay; Schlieker, Christian D.; Weihofen, Wilhelm A.; Ploegh, Hidde (Public Library of Science, 2011-03)
    Ubiquitin-dependent processes control much of cellular physiology. We show that expression of a highly active, Epstein-Barr virus-derived deubiquitylating enzyme (EBV-DUB) blocks proteasomal degradation of cytosolic and ...
  • Zhang, Chi; Spokoyny, Alexander M.; Zou, Yekui; Pentelute, Bradley L.; Simon, Mark (Wiley Blackwell, 2013-11)
    Singled out for special treatment: Naturally occurring glutathione S-transferase (GST) was used to catalyze an efficient “click” ligation between polypeptides with an N-terminal glutathione sequence and biomolecules or ...
  • Zhang, Chi; Dai, Peng; Spokoyny, Alexander M.; Pentelute, Bradley L. (American Chemical Society (ACS), 2014-07)
    A glutathione S-transferase (GST) catalyzed macrocyclization reaction for peptides up to 40 amino acids in length is reported. GST catalyzes the selective SNAr reaction between an N-terminal glutathione (GSH, γ-Glu-Cys-Gly) ...
  • Rashidian, Mohammad; Wang, Lu; Edens, Jerre G.; Jacobsen, Johanne T.; Hossain, Intekhab; Wang, Qifan; Victora, Gabriel D.; Vasdev, Neil; Liang, Steven H.; Ploegh, Hidde (Wiley Blackwell, 2016-01)
    Antibodies are currently the fastest-growing class of therapeutics. Although naked antibodies have proven valuable as pharmaceutical agents, they have some limitations, such as low tissue penetration and a long circulatory ...
  • Vemula, Praveen; Cruikshank, Gregory; John, George; Karp, Jeffrey Michael (Institute of Electrical and Electronics Engineers (IEEE), 2009-05)
    Utilization of enzyme catalysis as a tool to disassemble self-assembled hydrogels to control the release encapsulated drug provides an opportunity to design a wide range of enzyme-specific low-molecular-weight hydrogelators ...
  • Chryssostomidis, Chryssostomos; Karniadakis, George E.; Yang, Xiu; Venturi, Daniele; Chen, Changsheng (American Geophysical Union (AGU), 2010-12)
    Sensor placement at the extrema of empirical orthogonal functions (EOFs) is efficient and leads to accurate reconstruction of the ocean state from a limited number of measurements. In this paper, we develop important new ...
  • Cappallo, Roger J.; Corey, Brian E.; Goeke, Robert F.; Hewitt, Jacqueline N.; Kincaid, Barton B.; Kratzenberg, Eric W.; Lonsdale, Colin John; McWhirter, Stephen R.; Morgan, Edward H.; Oberoi, Divya; Remillard, Ronald Alan; Rogers, Alan E. E.; Salah, J. E.; Whitney, Alan R.; Williams, Christopher Leigh (Oxford University Press, 2012-11)
    Using the final 128 antenna locations of the Murchison Widefield Array (MWA), we calculate its sensitivity to the epoch of reionization (EoR) power spectrum of redshifted 21 cm emission for a fiducial model and provide the ...
  • Pillsbury, Liam; Weber, Thomas; Scandella, Benjamin; Ruppel, Carolyn; Hemond, Harold F; Juanes, Ruben (American Geophysical Union (AGU), 2016-05)
    Methane is a potent greenhouse gas whose emission from sediments in inland waters and shallow oceans may both contribute to global warming and be exacerbated by it. The fraction of methane emitted by sediments that bypasses ...
  • Dragomir, Diana (IOP Publishing, 2016-12)
    We report the discovery of EPIC 201702477b, a transiting brown dwarf in a long period (40.73691 ± 0.00037 day) and eccentric (e = 0.2281 ± 0.0026) orbit. This system was initially reported as a planetary candidate based ...
  • Nowak, Grzegorz; Palle, Enric; Gandolfi, Davide; Lanza, Antonino F.; Hirano, Teruyuki; Barragán, Oscar; Fukui, Akihiko; Bruntt, Hans; Endl, Michael; Cochran, William D.; Moroni, Pier G. Prada; Prieto-Arranz, Jorge; Kiilerich, Amanda; Nespral, David; Hatzes, Artie P.; Albrecht, Simon; Deeg, Hans; Winn, Joshua N.; Kuzuhara, Masayuki; Grziwa, Sascha; Smith, Alexis M. S.; Guenther, Eike W.; Van Eylen, Vincent; Csizmadia, Szilard; Fridlund, Malcolm; Cabrera, Juan; Eigmüller, Philipp; Erikson, Anders; Korth, Judith; Narita, Norio; Pätzold, Martin; Rauer, Heike; Ribas, Ignasi; Dai, Fei; Yu, Liang (IOP Publishing, 2017-02)
  • Farrahi, Katayoun; Emonet, Remi; Cebrian, Manuel (Public Library of Science, 2014-05)
    Traditional contact tracing relies on knowledge of the interpersonal network of physical interactions, where contagious outbreaks propagate. However, due to privacy constraints and noisy data assimilation, this network is ...
  • Guillebaud, Julia; Mahamadou, Aboubacar; Zamanka, Halima; Katzelma, Mariama; Arzika, Ibrahim; Ibrahim, Maman L; Duchemin, Jean-Bernard; Eltahir, Elfatih A. B.; Labbo, Rabiou; Druilhe, Pierre; Fandeur, Thierry (BioMed Central Ltd., 2013-10)
    Background: Few data are available about malaria epidemiological situation in Niger. However, implementation of new strategies such as vaccination or seasonal treatment of a target population requires the knowledge of ...
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