Advanced Search
DSpace@MIT

Browsing MIT Open Access Articles by Title

Research and Teaching Output of the MIT Community

Browsing MIT Open Access Articles by Title

Sort by: Order: Results:

  • Patel, Shyamal; Lorincz, Konrad; Hughes, Richard; Huggins, Nancy; Growdon, John; Standaert, David; Akay, Metin; Dy, Jennifer; Welsh, Matt; Bonato, Paolo (Institute of Electrical and Electronics Engineers, 2009-11)
    This paper presents the results of a pilot study to assess the feasibility of using accelerometer data to estimate the severity of symptoms and motor complications in patients with Parkinson's disease. A support vector ...
  • Loving, Galen S.; Sainlos, Matthieu; Imperiali, Barbara (Elsevier B.V., 2010-02)
    Solvatochromic fluorophores possess emission properties that are sensitive to the nature of the local microenvironment. These dyes have been exploited in applications ranging from the study of protein structural dynamics ...
  • Lukovic, Elvedin; Taylor, Elizabeth Vogel; Imperiali, Barbara (Wiley Blackwell (John Wiley & Sons), 2009-08)
    The best of both worlds: Combining a recombinant docking domain (see picture, blue ribbon) with a chemical sensing module (green hexagons) yields a highly selective ERK sensor. This probe exclusively monitors ERK1/2 activity ...
  • Lukovic, Elvedin; Taylor, Elizabeth Vogel; Imperiali, Barbara (Wiley-Blackwell Pubishers, 2009-08)
    Protein kinases are important regulators of cellular function, and the dynamics of their activities are critical indicators of the health or pathology of living systems.[1, 2] In particular, extracellular-signal regulated ...
  • Mukundan, Harish; Modarres-Sadeghi, Yahya; Dahl, Jason Michael; Hover, Franz S.; Triantafyllou, Michael S. (Elsevier Ltd., 2009-05)
    Long flexible cylinders (e.g., risers, tendons and mooring lines) exposed to the marine environment encounter ocean currents leading to vortex-induced vibration (VIV). These oscillations, often driven at high frequencies ...
  • Reithofer, Michael R.; Dobereiner, Graham E.; Schrock, Richard Royce; Muller, Peter (American Chemical Society (ACS), 2013-05)
    We report the synthesis of Mo and W MAP complexes that contain O-2,6-(2,5-R[subscript 2]-pyrrolyl)[subscript 2]C[subscript 6]H[subscript 3] (2,6-dipyrrolylphenoxide or ODPP[superscript R]) ligands in which R = i-Pr, Ph. ...
  • Skipper, Paul L.; Kim, Min Young; Sun, H. -L. Patty; Wogan, Gerald N.; Tannenbaum, Steven Robert (Oxford University Press, 2009-12)
    Alkylanilines are a group of chemicals whose ubiquitous presence in the environment is a result of the multitude of sources from which they originate. Exposure assessments indicate that most individuals experience lifelong ...
  • Zhu, Guangyu; Myint, MyatNoeZin; Ang, Wee Han; Song, Lina; Lippard, Stephen J. (American Association for Cancer Research, 2011-12)
    To overcome drug resistance and reduce the side effects of cisplatin, a widely used antineoplastic agent, major efforts have been made to develop next generation platinum-based anticancer drugs. Because cisplatin–DNA adducts ...
  • Wang, Jianfei; Zens, Timothy; Hu, Juejun; Becla, Piotr; Kimerling, Lionel C.; Agarwal, Anuradha Murthy (American Institute of Physics (AIP), 2012-05)
    In this paper, we present experimental demonstration of a resonant-cavity-enhanced mid-infrared photodetector monolithically fabricated on a silicon substrate. Dual-band detection at 1.6 μm and 3.7 μm is achieved within a ...
  • Liu, Jifeng; Sun, Xiaochen; Cai, Yan; Kimerling, Lionel C.; Michel, Jurgen; Camacho-Aguilera, Rodolfo Ernesto (Institute of Electrical and Electronics Engineers (IEEE), 2010-09)
    We report room temperature Ge-on-Si lasers with direct gap emission at 1590-1610 nm. Modeling of Ge/Si double heterojunction structures, which is supported by experimental results of Ge/Si LEDs, indicates the feasibility ...
  • Unknown author (Institute of Electrical and Electronics Engineers (IEEE), 2008-10)
    We summarize our work on creating substrate platforms, processes, and devices for the monolithic integration of silicon CMOS circuits with III-V optical and electronic devices. Visible LEDs and InP HBTs have been integrated ...
  • Tingley, Peter William (National Academy of Sciences of Ukraine (SIGMA (Symmetry, Integrability, and Geometry: Methods and Application)), 2010-04)
    Recently Fayers introduced a large family of combinatorial realizations of the fundamental crystal B(Λ[subscript 0]) for [^ over sl][subscript n], where the vertices are indexed by certain partitions. He showed that special ...
  • Corbett, Kevin D.; Yip, Calvin K.; Ee, Ly-Sha; Walz, Thomas; Amon, Angelika B.; Harrison, Stephen C. (Elsevier B.V., 2010-08)
    The monopolin complex regulates different types of kinetochore-microtubule attachments in fungi, ensuring sister chromatid co-orientation in Saccharomyces cerevisiae meiosis I and inhibiting merotelic attachment in ...
  • Ashlagi, Itai; Braverman, Mark; Hassidim, Avinatan; Monderer, Dov (Econometric Society, 2010-09)
    Consider an environment with a finite number of alternatives, and agents with private values and quasilinear utility functions. A domain of valuation functions for an agent is a monotonicity domain if every finite-valued ...
  • Colding, Tobias; Minicozzi, William (National Academy of Sciences (U.S.), 2012-08)
    In this expository article, we discuss various monotonicity formulas for parabolic and elliptic operators and explain how the analysis of function spaces and the geometry of the underlining spaces are intertwined. After ...
  • Mukherjee, Sayak; Zhu, Jing; Zikherman, Julie; Parameswaran, Ramya; Kadlecek, Theresa A.; Wang, Qi; Au-Yeung, Byron; Ploegh, Hidde; Kuriyan, John; Das, Jayajit; Weiss, Arthur (American Association for the Advancement of Science, 2013-01)
    The Src and Syk families of kinases are two distinct sets of kinases that play critical roles in initiating membrane-proximal B cell receptor (BCR) signaling. However, unlike in other lymphocytes, such as T cells, the ...
  • Avalos, Ana M.; Bilate, Angelina M.; Witte, Martin D.; Tai, Albert K.; He, Jiang; Frushicheva, Maria P.; Thill, Peter Daniel; Meyer-Wentrup, Friederike; Theile, Christopher S.; Chakraborty, Arup K.; Zhuang, Xiaowei; Ploegh, Hidde (Rockefeller University Press, 2014-02)
    Valency requirements for B cell activation upon antigen encounter are poorly understood. OB1 transnuclear B cells express an IgG1 B cell receptor (BCR) specific for ovalbumin (OVA), the epitope of which can be mimicked ...
  • Silver, David; Veness, Joel; Ng, Kee Siong; Hutter, Marcus; Uther, William (AI Access Foundation, 2011-01)
    This paper introduces a principled approach for the design of a scalable general reinforcement learning agent. Our approach is based on a direct approximation of AIXI, a Bayesian optimality notion for general reinforcement ...
  • Jiang, Fu-Jiun; Kampfer, Florian; Nyfeler, M. (American Physical Society, 2009-07)
    Motivated by the possible mechanism for the pinning of the electronic liquid crystal direction in YBa2Cu3O6.45 [YBa subscript 2 Cu supscript 3 O subscript 6.45] as proposed by Pardini et al. [Phys. Rev. B 78, 024439 (2008)], ...
  • Xu, Zao; Yue, Dick K. P. (Society of Photo-Optical Instrumentation Engineers (SPIE), 2014-02)
    We present a numerical study of the near-surface underwater solar light statistics using the state-of-the-art Monte Carlo radiative transfer (RT) simulations in the coupled atmosphere-ocean system. Advanced variance-reduction ...
Open Access