Advanced Search
DSpace@MIT

Browsing MIT Open Access Articles by Title

Research and Teaching Output of the MIT Community

Browsing MIT Open Access Articles by Title

Sort by: Order: Results:

  • Li, Deyu; Delaney, James C.; Page, Charlotte M.; Yang, Xuedong; Chen, Alvin S.; Wong, Cintyu; Drennan, Catherine L.; Essigmann, John M. (American Chemical Society (ACS), 2012-04)
    The DNA and RNA repair protein AlkB removes alkyl groups from nucleic acids by a unique iron- and α-ketoglutarate-dependent oxidation strategy. When alkylated adenines are used as AlkB targets, earlier work suggests that ...
  • Sontag, Emily M.; Joachimiak, Lukasz A.; Tan, Zhiqun; Tomlinson, Anthony; Housman, David E.; Glabe, Charles G.; Potkin, Steven G.; Frydman, Judith; Thompson, Leslie M. (National Academy of Sciences (U.S.), 2013-01)
    Aggregation of misfolded proteins is characteristic of a number of neurodegenerative diseases, including Huntington disease (HD). The CCT/TRiC (chaperonin containing TCP-1/TCP-1 ring) chaperonin complex can inhibit aggregation ...
  • Stein, Itai Y.; Lachman-Senesh, Noa; Devoe, Mackenzie E.; Wardle, Brian L. (American Chemical Society (ACS), 2014-05)
    Here we present a study on the presence of physisorbed water on the surface of aligned carbon nanotubes (CNTs) in ambient conditions, where the wet CNT array mass can be more than 200% larger than that of dry CNTs, and ...
  • Lander, Eric S. (Nature Publishing Group, 2013-03)
    The incidence of esophageal adenocarcinoma (EAC) has risen 600% over the last 30 years. With a 5-year survival rate of ~15%, the identification of new therapeutic targets for EAC is greatly important. We analyze the mutation ...
  • Altshuler, David (Springer-Verlag, 2012-11)
    Aims/hypothesis: Human complex metabolic traits are in part regulated by genetic determinants. Here we applied exome sequencing to identify novel associations of coding polymorphisms at minor allele frequencies (MAFs) >1% ...
  • Lander, Eric Steven (Nature Publishing Group, 2015-08)
    Myocardial infarction (MI), a leading cause of death around the world, displays a complex pattern of inheritance. When MI occurs early in life, the role of inheritance is substantially greater. Previously, rare mutations ...
  • Lander, Eric S.; Barbieri, Christopher E.; Baca, Sylvan C.; Lawrence, Michael S.; Demichelis, Francesca; Blattner, Mirjam; Theurillat, Jean-Philippe; White, Thomas A.; Stojanov, Petar; Van Allen, Eliezer; Stransky, Nicolas; Nickerson, Elizabeth; Chae, Sung-Suk; Boysen, Gunther; Auclair, Daniel; Onofrio, Robert; Park, Kyung; Kitabayashi, Naoki; MacDonald, Theresa Y.; Sheikh, Karen (Nature Publishing Group, 2012-05)
    Prostate cancer is the second most common cancer in men worldwide and causes over 250,000 deaths each year. Overtreatment of indolent disease also results in significant morbidity. Common genetic alterations in prostate ...
  • Fabrycky, Daniel C.; Winn, Joshua Nathan (American Astronomical Society, 2009-04)
    One possible diagnostic of planet formation, orbital migration, and tidal evolution is the angle ψ between a planet's orbital axis and the spin axis of its parent star. In general, ψ cannot be measured, but for transiting ...
  • Seager, Sara; Deming, Drake (Annual Reviews, 2010-06)
    At the dawn of the first discovery of exoplanets orbiting Sun-like stars in the mid-1990s, few believed that observations of exoplanet atmospheres would ever be possible. After the 2002 Hubble Space Telescope detection of ...
  • Smith, Matthew William; Seager, Sara; Pong, Christopher Masaru; Villasenor, Jesus Noel Samonte; Ricker, George R.; Miller, David W.; Knapp, Mary E.; Farmer, Grant Trapnell; Jensen-Clem, Rebecca M. (SPIE, 2010-07)
    Nanosatellites, i.e. spacecraft that weigh between 1 and 10 kg, are drawing increasing interest as platforms for conducting on-orbit science. This trend is primarily driven by the ability to piggyback nanosatellites on the ...
  • Saenz-Vash, Veronica; Yua, Miao; Romer, Katherine A.; Nieland, Thomas J.; Xu, Shangzhe; Penman, Marsha L.; Yesilaltay, Ayce; Carr, Steven A.; Krieger, Monty (Proceedings of the National Academy of Sciences (PNAS), 2011-07)
    The HDL receptor, scavenger receptor, class B, type I (SR-BI), is a homooligomeric cell surface glycoprotein that controls HDL structure and metabolism by mediating the cellular selective uptake of lipids, mainly cholesteryl ...
  • Herr, Hugh M. (BioMed Central Ltd., 2009-06)
    For over a century, technologists and scientists have actively sought the development of exoskeletons and orthoses designed to augment human economy, strength, and endurance. While there are still many challenges associated ...
  • Herr, Hugh M. (BioMed Central Ltd., 2009-06)
    For over a century, technologists and scientists have actively sought the development of exoskeletons and orthoses designed to augment human economy, strength, and endurance. While there are still many challenges associated ...
  • Ge, Ruowen; Tan, Evan; Asada, Haruhiko; Sharghi Namini, Soheila (Springer Netherlands, 2012-05)
    Cancer is a complex organ whose behavior is not only influenced by genetic and epigenetic changes in cancer cells but also by stromal cells, local extracellular matrix and specific tissue architecture. Intercellular ...
  • Turnbull, Margaret; Sparks, William; Thomson, Mark; Shaklan, Stuart B.; Roberge, Aki; Kuchner, Marc; Kasdin, N. Jeremy; Domagal-Goldman, Shawn; Cash, Webster; Warfield, Keith; Lisman, Doug; Scharf, Dan; Webb, David; Trabert, Rachel; Martin, Stefan; Cady, Eric; Heneghan, Cate; Seager, Sara (SPIE, 2015-08)
    Exo-S is a direct imaging space-based mission to discover and characterize exoplanets. With its modest size, Exo-S bridges the gap between census missions like Kepler and a future space-based flagship direct imaging exoplanet ...
  • Graham, Peter W.; Harnik, Roni; Rajendran, Surjeet; Saraswat, Prashant (American Physical Society, 2010-09)
    We propose a novel mechanism for dark matter to explain the observed annual modulation signal at DAMA/LIBRA which avoids existing constraints from every other dark matter direct detection experiment including CRESST, CDMS, ...
  • Seidel, Paul Alfred (Mathematical Sciences Publishers, 2015-01)
    Consider cotangent bundles of exotic spheres with their canonical symplectic structure. They admit automorphisms that preserve the part at infinity of one fiber and which are analogous to the square of a Dehn twist. Pursuing ...
  • Barros, Kipton; Chern, Gia-Wei; Batista, C. D.; Venderbos, Jorn W. F. (American Physical Society, 2014-12)
    We consider the Kondo-lattice model on the kagome lattice and study its weak-coupling instabilities at band filling fractions for which the Fermi surface has singularities. These singularities include Dirac points, quadratic ...
  • Serbyn, Maksym; Senthil, Todadri; Lee, Patrick Lee (American Physical Society, 2011-11)
    Motivated by recent experiments on the material Ba₃NiSb₂O₉, we consider a spin-one quantum antiferromagnet on a triangular lattice with the Heisenberg bilinear and biquadratic exchange interactions and a single-ion anisotropy. ...
  • Harris, Daniel Martin; Molacek, Jan; Bush, John W. M.; Wind-Willassen, Oistein (American Institute of Physics (AIP), 2013-08)
    We present the results of an integrated experimental and theoretical investigation of droplets bouncing on a vibrating fluid bath. A comprehensive series of experiments provides the most detailed characterisation to date ...
Open Access