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Browsing MIT Open Access Articles by Title

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  • Goossens, Sander; Sabaka, Terence J.; Nicholas, Joseph B.; Lemoine, Frank G.; Rowlands, David D.; Mazarico, Erwan Matias; Neumann, Gregory A.; Smith, David Edmund; Zuber, Maria (American Geophysical Union (AGU), 2014-05)
    We estimated a high-resolution local gravity field model over the south pole of the Moon using data from the Gravity Recovery and Interior Laboratory's extended mission. Our solution consists of adjustments with respect ...
  • Mag Washietl, Stefan; Kheradpour, Pouya; Ernst, Jason; Ward, Lucas D.; Jungreis, Irwin; Rasmussen, Matthew D.; Kellis, Manolis (Nature Publishing Group, 2011-10)
    The comparison of related genomes has emerged as a powerful lens for genome interpretation. Here we report the sequencing and comparative analysis of 29 eutherian genomes. We confirm that at least 5.5% of the human genome ...
  • Reeder, Christopher; Closser, Michael; Poh, Huay Mei; Sandhu, Kuljeet; Wichterle, Hynek; Gifford, David K. (Public Library of Science, 2015-05)
    RNA Polymerase II ChIA-PET data has revealed enhancers that are active in a profiled cell type and the genes that the enhancers regulate through chromatin interactions. The most commonly used computational method for ...
  • Le, Tung Ba Khanh; Imakaev, Maksim Viktorovich; Mirny, Leonid A.; Laub, Michael T. (American Association for the Advancement of Science (AAAS), 2013-10)
    Chromosomes must be highly compacted and organized within cells, but how this is achieved in vivo remains poorly understood. We report the use of chromosome conformation capture coupled with deep sequencing (Hi-C) to map ...
  • Bayro, Marvin J.; Griffin, Robert Guy; Maly, Thorsten; Birkett, Neil R.; Dobson, Christopher M.; MacPhee, Cait E. (American Chemical Society (ACS), 2010-07)
    The SH3 domain of the PI3 kinase (PI3-SH3 or PI3K-SH3) readily aggregates into fibrils in vitro and has served as an important model system in the investigation of the molecular properties and mechanism of formation of ...
  • Harman, Michelle; Li, Xingde; Pitris, Costas; Ghanta, Ravi; Fujimoto, James G.; Stamper, Debra L.; Brezinski, Mark E.; Martin, Scott (BioMed Central Ltd, 2005-01)
    This study demonstrates the first real-time imaging in vivo of human cartilage in normal and osteoarthritic knee joints at a resolution of micrometers, using optical coherence tomography (OCT). This recently developed ...
  • Leeb, Steven B.; Paris, James; Avestruz, Al-Thaddeus; Wichakool, Warit (Institute of Electrical and Electronics Engineers, 2010-02)
    This paper presents a high-resolution, physically-windowed sensor architecture that is well-suited for energy scorekeeping and diagnostic applications. The sensor can track a large-scale main signal while capturing small-scale ...
  • Wichakool, Warit; Paris, James; Avestruz, Al-Thaddeus; Leeb, Steven B. (Institute of Electrical and Electronics Engineers (IEEE), 2010-03)
    This paper presents a high-resolution, physically-windowed sensor architecture that is well-suited for energy scorekeeping and diagnostic applications. The sensor can track a large-scale main signal while capturing small-scale ...
  • Keller, Stefan C.; Casey, Andrew R.; Asplund, Martin; Bessell, Michael S.; Costa, Gary S. Da; Lind, Karin; Marino, Anna F.; Norris, John E.; Schmidt, Brian P.; Tisserand, Patrick; Walsh, Jennifer M.; Yong, David; Yu, Qinsi; Jacobson, Heather; Frebel, Anna L.; Pena, Jose M. (IOP Publishing, 2015-07)
    The SkyMapper Southern Sky Survey is carrying out a search for the most metal-poor stars in the Galaxy. It identifies candidates by way of its unique filter set which allows for estimation of stellar atmospheric parameters. ...
  • Aoki, Wako; Beers, Timothy C.; Lee, Young Sun; Honda, Satoshi; Ito, Hiroko; Takada-Hidai, Masahide; Frebel, Anna L.; Suda, Takuma; Fujimoto, Masayuki Y.; Carollo, Daniela; Sivarani, Thirupathi (IOP Publishing, 2012-12)
    Chemical compositions are determined based on high-resolution spectroscopy for 137 candidate extremely metal-poor (EMP) stars selected from the Sloan Digital Sky Survey (SDSS) and its first stellar extension, the Sloan ...
  • Simon, Joshua D.; Geha, Marla; Ji, Alexander Pung; Frebel, Anna L. (IOP Publishing, 2016-01)
    We present high-resolution Magellan/MIKE spectra of the four brightest confirmed red giant stars in the ultra-faint dwarf galaxy Bootes II (Boo II). These stars all inhabit the metal-poor tail of the Boo II metallicity ...
  • Gayou, Olivier; Monaghan, Peter; Qiang, Yi (American Physical Society, 2009-11)
    An experimental study of the 16O(e,e′K+)Λ16N [superscript 16 O (e, e prime K superscript +) superscript 16 subscript lambda N] reaction has been performed at Jefferson Lab. A thin film of falling water was used as a target. ...
  • Fang, Taotao; Canizares, Claude R.; Marshall, Herman Lee (IOP Publishing, 2005-01)
    We present a survey of six low- to moderate-redshift quasars with Chandra and XMM-Newton. The primary goal is to search for the narrow X-ray absorption lines produced by highly ionized metals in the warm-hot intergalactic ...
  • Kim, Kyoohyun; Yoon, HyeOk; Dao, Ming; Park, YongKeun; Diez Silva, Monica; Dasari, Ramachandra Rao (SPIE, 2013-06)
    We present high-resolution optical tomographic images of human red blood cells (RBC) parasitized by malaria-inducing Plasmodium falciparum (Pf)-RBCs. Three-dimensional (3-D) refractive index (RI) tomograms are reconstructed ...
  • Chen, Yu; Andrews, Peter M.; Aguirre, Aaron Dominic; Schmitt, Joseph M.; Fujimoto, James G. (SPIE, 2007-05)
    Optical coherence tomography (OCT) is an emerging medical imaging technology that enables high-resolution, noninvasive, cross-sectional imaging of microstructure in biological tissues in situ and in real time. When combined ...
  • Kashif, Faisal Mahmood; Shafi, Imran; Ahmad, Jamil; Shah, Syed Ismail; Ikram, Ataul Aziz; Khan, Adnan Ahmad; Bashir, Sajid (European Association for Signal Processing / Hindawi, 2010-01)
    This work evaluates the performance of high-resolution quadratic time-frequency distributions (TFDs) including the ones obtained by the reassignment method, the optimal radially Gaussian kernel method, the t-f autoregressive ...
  • Regev, Aviv; Brar, Gloria A.; Yassour, Moran; Friedman, Nir; Ingolia, Nicholas T.; Weissman, Jonathan S. (American Association for the Advancement of Science (AAAS), 2011-12)
    Meiosis is a complex developmental process that generates haploid cells from diploid progenitors. We measured messenger RNA (mRNA) abundance and protein production through the yeast meiotic sporulation program and found ...
  • Ragan, Timothy; Sylvan, Jeremy D.; Kim, Ki Hean; Huang, Hayden; Bahlmann, Karsten; Lee, Richard T.; So, Peter T. C. (SPIE, 2007-02)
    Three-dimensional (3-D) tissue imaging offers substantial benefits to a wide range of biomedical investigations from cardiovascular biology, diabetes, Alzheimer’s disease to cancer. Two-photon tissue cytometry is a novel ...
  • Zhekov, Svetozar A.; McCray, Richard; Dewey, Dan; Canizares, Claude R.; Borkowski, Kazimierz J.; Burrows, David N.; Park, Sangwook (American Astronomical Society, 2009-02)
    We present an extended analysis of the deep Chandra LETG and HETG observations of the supernova remnant 1987A (SNR 1987A) carried out in 2007. The global fits to the grating spectra show that the temperature of the X-ray ...
  • Schulz, Norbert S.; Gu, Ming F.; Nowak, Michael A.; Canizares, Claude R. (American Astronomical Society, 2009-04)
    High-resolution X-ray absorption spectroscopy is a powerful diagnostic tool for probing chemical and physical properties of the interstellar medium (ISM) at various phases. We present detections of K transition absorption ...
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