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Browsing MIT Open Access Articles by Title

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  • Lander, Eric S. (Nature Publishing Group, 2014-09)
    Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great Lakes of East Africa. To understand the molecular mechanisms underlying cichlid phenotypic diversity, we sequenced the genomes ...
  • Sealfon, Rachel S.; Lander, Eric S. (American Association for the Advancement of Science (AAAS), 2014-08)
    In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone to ~2000× coverage. We observed a rapid ...
  • Kellis, Manolis (Nature Publishing Group, 2013-05)
    Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain unknown. Most associated variants are not ...
  • Felkner, John S.; Townsend, Robert (Oxford University Press, 2011)
    A nation's economic geography can have an enormous impact on its development. In Thailand, we show that a high concentration of enterprise in an area predicts high subsequent growth in and around that area. We also find ...
  • Onnela, Jukka-Pekka; Arbesman, Samuel; Gonzalez, Marta C.; Barabasi, Albert-Laszlo; Christakis, Nicholas A. (Public Library of Science, 2011-04)
    Social groups are fundamental building blocks of human societies. While our social interactions have always been constrained by geography, it has been impossible, due to practical difficulties, to evaluate the nature of ...
  • Efrat, Alon; Neumayer, Sebastian James; Modiano, Eytan H. (Institute of Electrical and Electronics Engineers (IEEE), 2012-03)
    Failures in fiber-optic networks may be caused by natural disasters, such as floods or earthquakes, as well as other events, such as an Electromagnetic Pulse (EMP) attack. These events occur in specific geographical ...
  • Calabrese, Francesco; Pereira, Francisco C.; Lorenzo, Giusy Di; Liu, Liang; Ratti, Carlo (Springer-Verlag, 2010-05)
    This paper deals with the analysis of crowd mobility during special events. We analyze nearly 1 million cell-phone traces and associate their destinations with social events. We show that the origins of people attending ...
  • Autor, David H.; Dorn, David; Hanson, Gordon H. (American Economic Association, 2013-05)
    This paper explores the geographic overlap of trade and technology shocks across local labor markets in the United States. Regional exposure to technological change, as measured by specialization in routine task-intensive ...
  • Hawelka, Bartosz; Sitko, Izabela; Beinat, Euro; Sobolevsky, Stanislav; Kazakopoulos, Pavlos; Ratti, Carlo (Cartography & Geographic Information Society, 2014-02)
    Pervasive presence of location-sharing services made it possible for researchers to gain an unprecedented access to the direct records of human activity in space and time. This article analyses geo-located Twitter messages ...
  • Ghazanfari, Ehsan; Asanza Izquierdo, Enrique; Villamor Lora, Rafael (Springer Vienna, 2016-04)
    Understanding the reservoir conditions and material properties that govern the geomechanical behavior of shale formations under in situ conditions is of vital importance for many geomechanical applications. The development ...
  • Shabani, A.; Omar, Yasser; Rabitz, H.; Mohseni, Masoud; Lloyd, Seth (American Institute of Physics (AIP), 2013-05)
    We explore various design principles for efficient excitation energy transport in complex quantum systems. We investigate energy transfer efficiency in randomly disordered geometries consisting of up to 20 chromophores to ...
  • Belloni, Alexandre; Freund, Robert Michael (Springer Berlin, 2008-01)
    For a conic linear system of the form Ax ∈ K, K a convex cone, several condition measures have been extensively studied in the last dozen years.Among these, Renegar’s condition number C(A) is arguably the most prominent ...
  • Andrews, Isaiah; Mikusheva, Anna (The Econometric Society, 2016-05)
    Conventional tests for composite hypotheses in minimum distance models can be unreliable when the relationship between the structural and reduced‐form parameters is highly nonlinear. Such nonlinearity may arise for a variety ...
  • Modiano, Eytan H.; Chen, Li-Wei (Springer, 2009)
    In this chapter, we use an asymptotic analysis similar to the spherepacking argument in the proof of Shannon’s channel capacity theorem to derive optimal provisioning requirements for networks with both static and dynamic ...
  • Bertsimas, Dimitris J.; Goyal, Vineet; Sun, Xu Andy (Institute for Operations Research and the Management Sciences (INFORMS), 2011-02)
    In this paper, we show a significant role that geometric properties of uncertainty sets, such as symmetry, play in determining the power of robust and finitely adaptable solutions in multistage stochastic and adaptive ...
  • Anderson, Lara B.; Taylor, Washington (Springer-Verlag, 2014-08)
    We systematically analyze a broad class of dual heterotic and F-theory models that give four-dimensional supergravity theories, and compare the geometric constraints on the two sides of the duality. Specifically, we give ...
  • Baranski, Jan D.; Chaturvedi, Ritika R.; Stevens, Kelly R.; Eyckmans, Jeroen; Carvalho, Brian; Solorzano, Ricardo D.; Yang, Michael T.; Miller, Jordan S.; Bhatia, Sangeeta N.; Chen, Christopher S. (National Academy of Sciences (U.S.), 2013-05)
    Tissue vascularization and integration with host circulation remains a key barrier to the translation of engineered tissues into clinically relevant therapies. Here, we used a microtissue molding approach to demonstrate ...
  • Fathi, Ali; Moradian, Zabihallah; Rivard, Patrice; Ballivy, Gérard; Boyd, Andrew J. (Springer Vienna, 2015-08)
    Three-dimensional tracking of changes of asperities is one of the most important ways to illustrate shear mechanism of rock joints during testing. In this paper, the changes of the role of asperities during different stages ...
  • Lalley, Steven P.; Lawler, Gregory F.; Narayanan, Hariharan (Institute of Mathematical Statistics, 2009-12)
    Schramm-Loewner Evolution describes the scaling limits of interfaces in certain statistical mechanical systems. These interfaces are geometric objects that are not equipped with a canonical parametrization. The standard ...
  • Bousso, Raphael; Leichenauer, Stefan; Rosenhaus, Vladimir; Freivogel, Benjamin W. (American Physical Society (APS), 2011-10)
    We show that the geometry of cutoffs on eternal inflation strongly constrains predictions for the time scales of vacuum domination, curvature domination, and observation. We consider three measure proposals: the causal ...
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