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Browsing MIT Open Access Articles by Title

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  • Shah, Devavrat (Institute of Electrical and Electronics Engineers, 2009-04)
    Unlike the telephone network or the Internet, many of the next generation networks are not engineered for the purpose of providing efficient communication between various networked entities. Examples abound: sensor networks, ...
  • Jensen, Lars Juhl; Pasculescu, Adrian; Olhovsky, Marina; Colwill, Karen; Bork, Peer; Pawson, Tony; Linding, Rune; Yaffe, Michael B. (Oxford University Press (OUP), 2007-11)
    Protein kinases control cellular responses by phosphorylating specific substrates. Recent proteome-wide mapping of protein phosphorylation sites by mass spectrometry has discovered thousands of in vivo sites. Systematically ...
  • Acemoglu, Daron; Carvalho, Vasco M.; Ozdaglar, Asuman E.; Tahbaz-Salehi, Alireza (Econometric Society, 2012-09)
    This paper argues that in the presence of intersectoral input-output linkages, microeconomic idiosyncratic shocks may lead to aggregate fluctuations. We show, as the economy becomes more disaggregated, the rate at which ...
  • Kuperman, Gregory; Modiano, Eytan H. (Institute of Electrical and Electronics Engineers, 2013-04)
    We consider the problem of providing network protection that guarantees the maximum amount of time that flow can be interrupted after a failure. This is in contrast to schemes that offer no recovery time guarantees, such ...
  • Narula-Tam, Aradhana; Kuperman, Gregory; Modiano, Eytan H. (2012-06)
    We develop a novel network protection scheme that provides guarantees on both the fraction of time a flow has full connectivity, as well as a quantifiable minimum grade of service during downtimes. In particular, a flow ...
  • Neumayer, Sebastian James; Modiano, Eytan H. (Institute of Electrical and Electronics Engineers, 2010-05)
    Fiber-optic networks are vulnerable to natural disasters, such as tornadoes or earthquakes, as well as to physical failures, such as an anchor cutting underwater fiber cables. Such real-world events occur in specific ...
  • Alexopoulos, Leonidas G.; Rodriguez, Julio Saez; Cosgrove, Benjamin D.; Lauffenburger, Douglas A.; Sorger, Peter K. (American Society for Biochemistry and Molecular Biology (ASBMB), 2010-05)
    Systematic study of cell signaling networks increasingly involves high throughput proteomics, transcriptional profiling, and automated literature mining with the aim of assembling large-scale interaction networks. In ...
  • Soundararajan, Venkataramanan; Zheng, Shu; Patel, Neel; Warnock, Ken; Raman, Rahul; Wilson, Ian A.; Raguram, S.; Sasisekharan, V.; Sasisekharan, Ram (Nature Publishing Group, 2011-12)
    Influenza viral passaging through pre-vaccinated mice shows that emergent antigenic site mutations on the viral hemagglutinin (HA) impact host receptor-binding affinity and, therefore, the evolution of fitter influenza ...
  • Reinke, Aaron W.; Baek, Jiyeon; Ashenberg, Orr; Keating, Amy E. (American Association for the Advancement of Science (AAAS), 2013-05)
    Differences in biomolecular sequence and function underlie dramatic ranges of appearance and behavior among species. We studied the basic region-leucine zipper (bZIP) transcription factors and quantified bZIP dimerization ...
  • Hidalgo, Cesar A.; Hausmann, Ricardo (Springer-Verlag, 2011-12)
    Much of the analysis of economic growth has focused on the study of aggregate output. Here, we deviate from this tradition and look instead at the structure of output embodied in the network connecting countries to the ...
  • Meyer, Pablo; Cokelaer, Thomas; Chandran, Deepak; Kim, Kyung H; Loh, Po-Ru; Lipson, Mark; Berger, Bonnie; Kreutz, Clemens; Raue, Andreas; Steiert, Bernhard; Timmer, Jens; Bilal, Erhan; DREAM 6&7 Parameter Estimation consortium; Sauro, Herbert M; Stolovitzky, Gustavo; Saez-Rodriguez, Julio; Tucker, George Jay (BioMed Central Ltd, 2014-02)
    Background: Accurate estimation of parameters of biochemical models is required to characterize the dynamics of molecular processes. This problem is intimately linked to identifying the most informative experiments for ...
  • McRae, Kateri; Hughes, Brent; Chopra, Sita; Garbrieli, John D. E.; Gross, James J.; Ochsner, Kevin N. (MIT Press, 2010-02)
    Distraction and reappraisal are two commonly used forms of cognitive emotion regulation. Functional neuroimaging studies have shown that each one depends upon interactions between pFC, interpreted as implementing cognitive ...
  • Noel, Victor; Ryugo, David K.; Delgutte, Bertrand; Hancock, Kenneth E. (Society for Neuroscience, 2010-10)
    Human bilateral cochlear implant users do poorly on tasks involving interaural time differences (ITD), a cue that provides important benefits to the normal hearing, especially in challenging acoustic environments, yet the ...
  • Aldridge, J. Wayne; Tindell, Amy J.; Berridge, Kent C.; Zhang, Jun; Smith, Kyle S. (Public Library of Science, 2009-05)
    Incentive salience is a motivational property with ‘magnet-like’ qualities. When attributed to reward-predicting stimuli (cues), incentive salience triggers a pulse of ‘wanting’ and an individual is pulled toward the cues ...
  • Gershman, Samuel J.; Schapiro, Anna C.; Hupbach, Almut; Norman, Kenneth A. (Society for Neuroscience, 2013-05)
    What causes new information to be mistakenly attributed to an old experience? Some theories predict that reinstating the context of a prior experience allows new information to be bound to that context, leading to source ...
  • Blackburne, Liwei King; Eddy, Marianna D.; Kalra, Priya; Yee, Debbie; Sinha, Pawan; Gabrieli, John D. E. (Public Library of Science, 2014-05)
    Children often make letter reversal errors when first learning to read and write, even for letters whose reversed forms do not appear in normal print. However, the brain basis of such letter reversal in children learning ...
  • Meyers, Ethan M. (Frontiers Research Foundation, 2013-04)
    Population decoding is a powerful way to analyze neural data, however, currently only a small percentage of systems neuroscience researchers use this method. In order to increase the use of population decoding, we have ...
  • Saxe, Rebecca R.; Scholz, Jonathan; Young, Liane (Informa UK (Taylor & Francis), 2011-01)
    Moral judgment depends critically on theory of mind (ToM), reasoning about mental states such as beliefs and intentions. People assign blame for failed attempts to harm and offer forgiveness in the case of accidents. Here ...
  • Blackwell, William J. (Springer, 2012-03)
    Neural networks have been widely used to provide retrievals of geophysical parameters from spectral radiance measurements made remotely by air-, ground-, and space-based sensors. The advantages of retrievals based on neural ...
  • Leslie, R. Vincent; Blackwell, William J.; Bickmeier, Laura J.; Jairam, Laura G. (Society of Photo-Optical Instrumentation Engineers, 2008-12)
    We describe a simulation methodology used to develop and validate precipitation retrieval algorithms for current and future passive microwave sounders with emphasis on the NPOESS (National Polar-orbiting Operational ...
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