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Browsing MIT Open Access Articles by Title

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  • Manara, C. F.; Robberto, M.; Da Rio, N.; Lodato, G.; Hillenbrand, L. A.; Soderblom, D. R.; Stassun, Keivan (IOP Publishing, 2012-08)
    The present observational understanding of the evolution of the mass accretion rates ([dot over M][subscript acc]) in pre-main-sequence stars is limited by the lack of accurate measurements of [dot over M][subscript acc] ...
  • Placco, Vinicius M.; Beers, Timothy C.; Ivans, Inese I.; Filler, Dan; Imig, Julie A.; Roederer, Ian U.; Abate, Carlo; Hansen, Terese; Cowan, John J.; Lawler, James E.; Schatz, Hendrik; Sneden, Christopher; Sobeck, Jennifer S.; Aoki, Wako; Smith, Verne V.; Bolte, Michael; Frebel, Anna L. (IOP Publishing, 2015-10)
    We present an elemental-abundance analysis, in the near-ultraviolet (NUV) spectral range, for the bright carbon-enhanced metal-poor (CEMP) stars HD 196944 (V = 8.40, [Fe/H] = −2.41) and HD 201626 (V = 8.16, [Fe/H] = −1.51), ...
  • Placco, Vinicius M.; Beers, Timothy C.; Roederer, Ian U.; Cowan, John J.; Filler, Dan; Ivans, Inese I.; Lawler, James E.; Schatz, Hendrik; Sneden, Christopher; Sobeck, Jennifer S.; Aoki, Wako; Smith, Verne V.; Frebel, Anna L. (IOP Publishing, 2014-06)
    We present an elemental-abundance analysis, in the near-ultraviolet (NUV) spectral range, for the extremely metal-poor star BD+44°493 a ninth magnitude subgiant with [Fe/H] =–3.8 and enhanced carbon, based on data acquired ...
  • Samuels, Richard J.; Michishita, Narushige (Oxford University Press, 2012-10)
    After decades of accepting US supremacy in Asia as the foundation of its foreign and security policies, finding the right distance between the U.S. and China is the most important strategic choice facing Japan today. ...
  • Jeon, Jessie S.; Bersini, Simone; Gilardi, Mara; Dubini, Gabriele; Charest, Joseph L.; Moretti, Matteo; Kamm, Roger Dale (National Academy of Sciences (U.S.), 2015-01)
    A key aspect of cancer metastases is the tendency for specific cancer cells to home to defined subsets of secondary organs. Despite these known tendencies, the underlying mechanisms remain poorly understood. Here we develop ...
  • Fu, Dragony; Brophy, Jennifer Ann; Chan, Tsz Yan Clement; Atmore, Kyle Aaquil; Dedon, Peter C.; Samson, Leona D.; Begley, Ulrike; Begley, Thomas J.; Paules, Richard S. (American Society for Microbiology, 2010-03)
    tRNA nucleosides are extensively modified to ensure their proper function in translation. However, many of the enzymes responsible for tRNA modifications in mammals await identification. Here, we show that human AlkB homolog ...
  • Santer, Benjamin D.; Painter, Jeffrey F.; Bonfils, Celine; Mears, Carl A.; Solomon, Susan; Wigley, Tom M. L.; Gleckler, Peter J.; Schmidt, Gavin A.; Doutriaux, Charles; Gillett, Nathan P.; Taylor, Karl E.; Thorne, Peter W.; Wentz, Frank J. (National Academy of Sciences (U.S.), 2013-10)
    Since the late 1970s, satellite-based instruments have monitored global changes in atmospheric temperature. These measurements reveal multidecadal tropospheric warming and stratospheric cooling, punctuated by short-term ...
  • Saveski, Martin; Chu, Eric; Vosoughi, Soroush; Roy, Deb K. (Association for Computing Machinery (ACM), 2016-04)
    Most social network analyses focus on online social networks. While these networks encode important aspects of our lives they fail to capture many real-world connections. Most of these connections are, in fact, public and ...
  • Drake, Adam; Khoury, Maroun; Leskov, Ilya B.; Iliopoulou, Bettina P.; Fragoso, Maria F.; Lodish, Harvey F.; Chen, Jianzhu (Public Library of Science, 2011-04)
    Increasing demand for human hematopoietic stem cells (HSCs) in clinical and research applications necessitates expansion of HSCs in vitro. Before these cells can be used they must be carefully evaluated to assess their ...
  • Zhang, Haoqi; Law, Edith; Miller, Robert C.; Gajos, Krzysztof Z.; Parkes, David C.; Horvitz, Eric (Association for Computing Machinery (ACM), 2012-05)
    An important class of tasks that are underexplored in current human computation systems are complex tasks with global constraints. One example of such a task is itinerary planning, where solutions consist of a sequence of ...
  • Wanniarachchi, Yoshitha A.; Kaczmarek, Piotr; Wan, Andrea; Nolan, Elizabeth M. (American Chemical Society, 2011-09)
    Human α-defensin 5 (HD5, HD5[subscript ox] to specify the oxidized and disulfide linked form) is a 32-residue cysteine-rich host-defense peptide, expressed and released by small intestinal Paneth cells, that exhibits ...
  • Park, Seon Joo; Song, Hyun Seok; Kwon, Oh Seok; Chung, Ji Hyun; Lee, Seung Hwan; An, Ji Hyun; Ahn, Sae Ryun; Lee, Ji Eun; Yoon, Hyeonseok; Park, Tai Hyun; Jang, Jyongsik (Nature Publishing Group, 2014-03)
    The development of molecular detection that allows rapid responses with high sensitivity and selectivity remains challenging. Herein, we demonstrate the strategy of novel bio-nanotechnology to successfully fabricate ...
  • Metallo, Christian M.; Azarin, Samira M.; Moses, Laurel E.; Ji, Lin; Pablo, Juan J. de; Palecek, Sean P. (Mary Ann Liebert, 2010-01)
    Human embryonic stem (hES) cells are an attractive source of cellular material for scientific, diagnostic, and potential therapeutic applications. Protocols are now available to direct hES cell differentiation to specific ...
  • Sherley, James L. (Hindawi Publishing Corporation, 2004)
    In recent months, the American public has been bombarded with reports of prominent stem cell scientists attempting to run end-around plays against current US government policies that restrict research that requires the ...
  • Jaenisch, Rudolf; Hanna, Jacob; Cheng, Albert W.; Saha, Krishanu; Kim, Jongpil; Lengner, Christopher J.; Soldner, Frank; Cassady, John P.; Muffat, Julien; Carey, Bryce W. (National Academy of Sciences, 2010-05)
    Human and mouse embryonic stem cells (ESCs) are derived from blastocyst-stage embryos but have very different biological properties, and molecular analyses suggest that the pluripotent state of human ESCs isolated so far ...
  • Gostjeva, Elena V.; Thilly, William G.; Fomina, Janna N.; Darroudi, Firouz; Gruhl, Amanda Natalie (Elsevier, 2010-12)
    Metakaryotic cells and syncytia with large, hollow, bell-shaped nuclei demonstrate symmetrical and asymmetrical amitotic nuclear fissions in microanatomical positions and numbers expected of stem cell lineages in tissues ...
  • Rahmandad, Hazhir (Public Library of Science, 2014-12)
    Quantifying human weight and height dynamics due to growth, aging, and energy balance can inform clinical practice and policy analysis. This paper presents the first mechanism-based model spanning full individual life and ...
  • Grunwald, Martin; Muniyandi, Manivannan; Kim, Hyun; Kim, Jung; Krause, Frank; Mueller, Stephanie; Srinivasan, Mandayam A. (Frontiers Research Foundation, 2014-04)
    Introduction: The explorative scanning movements of the hands have been compared to those of the eyes. The visual process is known to be composed of alternating phases of saccadic eye movements and fixation pauses. Descriptive ...
  • So, Peter T. C.; Kim, Ki Hean; Sun, Tzu-Lin; Liu, Yuan; Sung, Ming-Chin; Chen, Hsiao-Ching; Yang, Chuen-Huei; Huang, Guan-Tarn; Lin, Wei-Chou; Chiou, Ling-Ling; Lin, Chih-Ju; Lee, Hsuan-Shu; Dong, Chen-Yuan; Hovhannisyan, Vladimir (SPIE, 2010-02)
    Conventionally, the diagnosis of hepatocellular carcinoma (HCC) is performed by qualitative examination of histopathological specimens, which takes times for sample preparation in fixation, section and stain. Our objective ...
  • Michini, Bernard J.; How, Jonathan P. (American Institute of Aeronautics and Astronautics, 2011-03)
    Aircraft carrier deck operations present a complex and uncertain environment in which time-critical scheduling and planning must be done, and to date all course of action planning is done solely by human operators who rely ...
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