Advanced Search
DSpace@MIT

Browsing MIT Open Access Articles by Title

Research and Teaching Output of the MIT Community

Browsing MIT Open Access Articles by Title

Sort by: Order: Results:

  • Gong, Nan-wei; Laibowitz, Mat; Paradiso, Joseph A. (New Interfaces for Musical Expression, 2009)
    In this project, we have developed a real-time writing instrument for music control. The controller, MusicGrip, can capture the subtle dynamics of the user’s grip while writing or drawing and map this to musical control ...
  • von Fintel, Kai; Gillies, Anthony S. (Springer Netherlands, 2010-05)
    It is a recurring matra that epistemic must creates a statement that is weaker than the corresponding flat-footed assertion: It must be raining vs. It’s raining. Contrary to classic discussions of the phenomenon such as ...
  • Sheh, Alexander; Lee, Chung-Wei; Masumura, Kenichi; Rickman, Barry H.; Nohmi, Takehiko; Wogan, Gerald N.; Fox, James G.; Schauer, David B. (National Academy of Sciences (U.S.), 2010-08)
    Helicobacter pylori is a human carcinogen, but the mechanisms evoked in carcinogenesis during this chronic inflammatory disease remain incompletely characterized. We determined whether chronic H. pylori infection induced ...
  • Yang, Yue; Huang, Jinghe; Toth, Ildiko; Lichterfeld, Mathias; Yu, Xu G. (Public Library of Science, 2010-12)
    Escape mutations in HIV-1 cytotoxic T cell (CTL) epitopes can abrogate recognition by the TCR of HIV-1-specific CD8+ T cells, but may also change interactions with alternative MHC class I receptors. Here, we show that ...
  • Lander, Eric S. (American Association for the Advancement of Science, 2011-07)
    Head and neck squamous cell carcinoma (HNSCC) is a common, morbid, and frequently lethal malignancy. To uncover its mutational spectrum, we analyzed whole-exome sequencing data from 74 tumor-normal pairs. The majority ...
  • Hobbie, Sven N.; Kalapala, Sarath K.; Bottger, Erik C.; Shcherbakov, Dmitry (Public Library of Science, 2010-04)
    Recent studies have suggested that ribosomal protein S12 modulates 16S rRNA function and susceptibility to 2-deoxystreptamine aminoglycosides. To study whether the non-restrictive K42R mutation in RpsL affects 2-deoxystreptamine ...
  • Leshchiner, Ignaty; Alexa, Kristen; Kelsey, Peter; Adzhubei, Ivan; Austin-Tse, Christina A.; Cooney, Jeffrey D.; Anderson, Heidi; King, Matthew J.; Stottmann, Rolf W.; Garnaas, Maija K.; Ha, Seungshin; Drummond, Iain A.; Paw, Barry H.; North, Trista E.; Beier, David R.; Goessling, Wolfram; Sunyaev, Shamil R. (Cold Spring Harbor Laboratory Press, 2012-05)
    Genetic mapping of mutations in model systems has facilitated the identification of genes contributing to fundamental biological processes including human diseases. However, this approach has historically required the prior ...
  • Melom, Jan Elizabeth; Littleton, J. Troy (Society for Neuroscience, 2013-01)
    Glia exhibit spontaneous and activity-dependent fluctuations in intracellular Ca[superscript 2+], yet it is unclear whether glial Ca[superscript 2+] oscillations are required during neuronal signaling. Somatic glial ...
  • Mullins, James I.; Heath, Laura; Hughes, James P.; Kicha, Jessica; Styrchak, Sheila; Wong, Kim G.; Rao, Ushnal; Hansen, Alexis; Harris, Kevin S.; Laurent, Jean-Pierre; Li, Deyu; Simpson, Jeffrey H.; Essigmann, John M.; Loeb, Lawrence A.; Parkins, Jeffrey (Public Library of Science, 2011-01)
    The deoxycytidine analog KP1212, and its prodrug KP1461, are prototypes of a new class of antiretroviral drugs designed to increase viral mutation rates, with the goal of eventually causing the collapse of the viral ...
  • Lees, Jacqueline; Caron, Alicia M.; Danielian, Paul S.; West, Julie C.; Stone, James R.; Berman, Seth D. (United States National Academy of Sciences, 2009-08)
    The retinoblastoma tumor-suppressor protein, pRb, is a member of the pocket protein family that includes p107 and p130. These proteins have well-defined roles in regulating entry into and exit from the cell cycle and also ...
  • Kirby, Andrew; Gnirke, Andreas; Jaffe, David B.; Baresova, Veronika; Pochet, Nathalie; Blumenstiel, Brendan; Ye, Chun; Aird, Daniel; Stevens, Christine; Robinson, James T.; Cabili, Moran N.; Gat-Viks, Irit; Kelliher, Edward; Daza, Riza; DeFelice, Matthew; Hulkova, Helena; Sovova, Jana; Vylet'al, Petr; Antignac, Corinne; Guttman, Mitchell; Handsaker, Robert E.; Perrin, Danielle; Steelman, Scott; Sigurdsson, Snaevar; Scheinman, Steven J.; Sougnez, Carrie; Cibulskis, Kristian; Parkin, Melissa; Green, Todd; Rossin, Elizabeth; Zody, Michael C.; Xavier, Ramnik J.; Pollak, Martin R.; Alper, Seth L.; Lindblad-Toh, Kerstin; Gabriel, Stacey; Hart, P. Suzanne; Regev, Aviv; Nusbaum, Chad; Kmoch, Stanislav; Bleyer, Anthony J.; Lander, Eric S.; Daly, Mark J. (Nature Publishing Group, 2013-02)
    Although genetic lesions responsible for some mendelian disorders can be rapidly discovered through massively parallel sequencing of whole genomes or exomes, not all diseases readily yield to such efforts. We describe the ...
  • Auerbach, Benjamin; Osterweil, Emily; Bear, Mark (Nature Publishing Group, 2011-11)
    Tuberous sclerosis complex and fragile X syndrome are genetic diseases characterized by intellectual disability and autism. Because both syndromes are caused by mutations in genes that regulate protein synthesis in neurons, ...
  • Houghton, JeanMarie; Li, Hanchen; Fan, Xueli; Liu, Yingwang; Liu, Jian Hua; Rao, Varada P.; Poutahidis, Theofilos; Taylor, Christie L.; Jackson, Erin A.; Hewes, Christine M.; Lyle, Stephen; Cerny, Anna; Bowen, Glennice; Cerny, Jan; Moore, Nathan; Kurt-Jones, Evelyn A.; Erdman, Susan E. (Mary Ann Liebert, 2010-07)
    Neoplastic epithelia may remain dormant and clinically unapparent in human patients for decades. Multiple risk factors including mutations in tumor cells or the stromal cells may affect the switch from dormancy to malignancy. ...
  • Ma, Long; Horvitz, H. Robert (Public Library of Science, 2009-11)
    The removal of introns from eukaryotic RNA transcripts requires the activities of five multi-component ribonucleoprotein complexes and numerous associated proteins. The lack of mutations affecting splicing factors essential ...
  • Ma, Long; Horvitz, H. Robert (Public Library of Science, 2009-11)
    The removal of introns from eukaryotic RNA transcripts requires the activities of five multi-component ribonucleoprotein complexes and numerous associated proteins. The lack of mutations affecting splicing factors essential ...
  • Kini, Lohith G.; Herrero-Jimenez, Pablo; Sanghvi, Jayodita; Gutierrez, Efren; Hensle, David; Kogel, John; Kusko, Rebecca; Rexer, Karl; Kurzweil, Ray; Refinetti, Paulo; Morgenthaler, Stephan; Koledova, Vera V.; Gostjeva, Elena V.; Thilly, William G.; Kamath, Tushar V. (Frontiers Research Foundation, 2013-10)
    Adult age-specific colorectal cancer incidence rates increase exponentially from maturity, reach a maximum, then decline in extreme old age. Armitage and Doll (1) postulated that the exponential increase resulted from “n” ...
  • Kou, Su-Peng; Yu, Jing; Wen, Xiao-Gang (American Physical Society, 2009-09)
    In this paper, we develop an effective mutual Chern-Simons Landau-Ginzburg (MCSLG) theory to describe the continuous topological quantum phase transition (TQPT). In particular, we consider the TQPT between a spin-polarized ...
  • Chan, Chung; Zheng, Lizhong (Institute of Electrical and Electronics Engineers, 2010-05)
    A mutual dependence expression is established for the secret key agreement problem when all users are active. In certain source networks, the expression can be interpreted as certain notions of connectivity and network ...
  • Khan, Mozaffar Nayim; Kogan, Leonid; Serafeim, George (American Finance Association, 2012-07)
    We use price pressure resulting from purchases by mutual funds with large capital inflows to identify overvalued equity. This is a relatively exogenous overvaluation indicator as it is associated with who is buying—buyers ...
  • Sheiretov, Yanko; Grundy, Dave; Zilberstein, Vladimir; Goldfine, Neil J.; Maley, Susan (Institute of Electrical and Electronics Engineers, 2009-10)
    Utilization of America's substantial coal reserves for energy production has become a national priority. Advanced coal-fired power plants offer an environmentally friendly means to achieve that goal. These power plants, ...
Open Access