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Browsing MIT Open Access Articles by Title

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  • Zhao, Wen-Ning; Cheng, Chialin; Theriault, Kraig M.; Sheridan, Steven D.; Tsai, Li-Huei; Haggarty, Stephen J. (Sage Publications, 2012-08)
    Wnt/β-catenin signaling has emerged as a central player in pathways implicated in the pathophysiology and treatment of neuropsychiatric disorders. To identify potential novel therapeutics for these disorders, high-throughput ...
  • Cox, David D.; Pinto, Nicolas; Doukhan, David; DiCarlo, James (Public Library of Science, 2009-11)
    While many models of biological object recognition share a common set of ‘‘broad-stroke’’ properties, the performance of any one model depends strongly on the choice of parameters in a particular instantiation of that ...
  • Pinto, Nicolas; Doukhan, David; DiCarlo, James; Cox, David D. (Public Library of Science, 2009-11)
    While many models of biological object recognition share a common set of “broad-stroke” properties, the performance of any one model depends strongly on the choice of parameters in a particular instantiation of that ...
  • Armiento, Rickard R.; Kozinsky, Boris; Hautier, Geoffroy; Fornari, Marco; Ceder, Gerbrand (American Physical Society, 2014-04)
    We screen a large chemical space of perovskite alloys for systems with optimal properties to accommodate a morphotropic phase boundary (MPB) in their composition-temperature phase diagram, a crucial feature for high ...
  • Watson, Christa; Ge, Jing; Cohen, Joel; Pyrgiotakis, Georgios; Engelward, Bevin P.; Demokritou, Philip (American Chemical Society (ACS), 2014-03)
    The likelihood of intentional and unintentional engineered nanoparticle (ENP) exposure has dramatically increased due to the use of nanoenabled products. Indeed, ENPs have been incorporated in many useful products and have ...
  • Steinmeyer, Joseph Daly; Yanik, Mehmet Fatih (Public Library of Science, 2012-04)
    The complexity of neurons and neuronal circuits in brain tissue requires the genetic manipulation, labeling, and tracking of single cells. However, current methods for manipulating cells in brain tissue are limited to ...
  • Lee, Seung-Kon; Baek, Jinyoung; Jensen, Klavs F. (American Chemical Society (ACS), 2014-02)
    Uniform polymer microbeads with highly loaded quantum dots (QDs) are produced using high-throughput coherent jet breakup of a biocompatible poly(ethylene glycol) diacrylate (PEGDA) prepolymer resin, followed by in-line ...
  • Kim, Daekeun; So, Peter T. C. (Society of Photo-optical Instrumentation Engineers, 2010-02)
    Two-photon excitation microfabrication has been shown to be useful in the field of photonics and biomedicine. It generates 3D microstructures and provides sub-diffraction fabrication resolution. Nevertheless, laser direct ...
  • Alver, Burak Han; Ballintijn, Maarten; Busza, Wit; Decowski, Michael P.; Gulbrandsen, K.; Henderson, C.; Kane, J. L.; Kulinich, Piotr; Li, Wei; Loizides, Constantin; Reed, C.; Roland, Christof E.; Roland, Gunther M.; Stephans, George S. F.; Vale, C.; van Nieuwenhuizen, Gerrit Jan; Vaurynovich, Siarhei S.; Verdier, Robin; Veres, Gabor; Wenger, Edward Allen; Wyslouch, Boleslaw (American Physical Society, 2010-02)
    A measurement of two-particle correlations with a high transverse momentum trigger particle (p[subscript T][superscript trig]>2.5  GeV/c) is presented for Au+Au collisions at √sNN=200   GeV over the uniquely broad ...
  • Miller, Eric D.; Bregman, Joel N.; Wakker, Bart P. (Institute of Physics/American Astronomical Society, 2009-02)
    We present deep H I 21 cm and optical observations of the face-on spiral galaxy M 83 obtained as part of a project to search for high-velocity clouds (HVCs) in nearby galaxies. Anomalous-velocity neutral gas is detected ...
  • Speck, Jared R.; Strain, Robert M. (Springer-Verlag, 2011-02)
    We study the local-in-time hydrodynamic limit of the relativistic Boltzmann equation using a Hilbert expansion. More specifically, we prove the existence of local solutions to the relativistic Boltzmann equation that are ...
  • Byrne, Alex (Springer Netherlands, 2015-12)
    Hill's views on visual experience are critically examined.
  • Abbott, Timothy G.; Abel, Zachary Ryan; Charlton, David; Demaine, Erik D.; Demaine, Martin L.; Kominers, Scott Duke (Springer-Verlag, 2012-01)
    We prove that any finite collection of polygons of equal area has a common hinged dissection. That is, for any such collection of polygons there exists a chain of polygons hinged at vertices that can be folded in the ...
  • Libert, Y.; Gerard, E.; Le Bertre, T.; Johnson, M. C.; Dame, T. M.; Matthews, Lynn D. (IOP Publishing, 2011-01)
    We report H I 21 cm line observations of the asymptotic giant branch (AGB) star X Her obtained with the Robert C. Byrd Green Bank Telescope (GBT) and the Very Large Array. We have unambiguously detected H I emission ...
  • Tonegawa, Susumu; Nakashiba, Toshiaki; Buhl, Derek L.; McHugh, Thomas J. (Cell Press, 2009-06)
    A widely held memory consolidation theory posits that memory of events and space is initially stored in the hippocampus (HPC) in a time-limited manner and is consolidated in the neocortex for permanent storage. Although ...
  • Sananbenesi, Farahnaz; Fischer, Andre; Wang, Xinyu; Schrick, Christina; Neve, Rachael L.; Radulovic, Jelena; Tsai, Li-Huei (Nature Publishing Group, 2007-07)
    Treatment of emotional disorders involves the promotion of extinction processes, which are defined as the learned reduction of fear. The molecular mechanisms underlying extinction have only begun to be elucidated. By ...
  • Kitamura, Takashi; Okubo-suzuki, Reiko; Takashima, Noriko; Murayama, Akiko; Hino, Toshiaki; Nishizono, Hirofumi; Kida, Satoshi; Inokuchi, Kaoru (BioMed Central Ltd, 2012-02)
    Background: During permanent memory formation, recall of acquired place memories initially depends on the hippocampus and eventually become hippocampus-independent with time. It has been suggested that the quality of ...
  • Neve, Rachael L.; Xia, Yan; Portugal, George S.; Fakira, Amanda K.; Melyan, Zara; Lee, H. Thomas; Russo, Scott J.; Liu, Jie; Morón, Jose A. (Society for Neuroscience, 2011-11)
    Glutamatergic systems, including AMPA receptors (AMPARs), are involved in opiate-induced neuronal and behavioral plasticity, although the mechanisms underlying these effects are not fully understood. In the present study, ...
  • Goosens, Ki Ann (Elsevier, 2011-05)
    For many years, the hippocampal formation has been implicated in the regulation of negative emotion, yet the nature of this link has remained elusive. Recent studies have made important links between the hippocampus and ...
  • Davidson, Thomas J.; Kloosterman, Fabian; Wilson, Matthew A. (Elsevier B.V., 2009-08)
    During pauses in exploration, ensembles of place cells in the rat hippocampus re-express firing sequences corresponding to recent spatial experience. Such “replay” co-occurs with ripple events: short-lasting (∼50–120 ms), ...
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