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Browsing MIT Open Access Articles by Title

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  • Spellmeyer, Neal W.; Kerman, Andrew J.; Molnar, Richard J.; Berggren, Karl K.; Moores, John D.; Hamilton, Scott A. (Institute of Electrical and Electronics Engineers (IEEE), 2010-07)
    We demonstrate the potential for 1.85 Mbit/s secure key rates over 101 km of fiber, >100 times faster than previously demonstrated, using the differential phase shift quantum key distribution protocol and superconducting ...
  • Bautz, Marshall W.; McDonald, Michael A. (Institute of Physics/American Astronomical Society, 2012-12)
    We report the first investigation of cool-core properties of galaxy clusters selected via their Sunyaev-Zel'dovich (SZ) effect. We use 13 galaxy clusters uniformly selected from 178 deg[superscript 2] observed with the ...
  • Ippen, Erich P.; Morse, Jonathan Lee; Sickler, J. L.; Chen, J.; Kaertner, Franz X. (Institute of Electrical and Electronics Engineers, 2009-08)
    A 301 MHz fundamentally mode-locked erbium fiber ring laser generating 108 fs pulses is demonstrated. Novel combination of gain fiber with anomalous group-velocity dispersion and intra-cavity silicon with normal group-velocity ...
  • Laserson, Uri; Vigneault, Francois; Gadala-Maria, Daniel; Yaari, Gur; Uduman, Mohamed; Vander Heiden, Jason A.; Kelton, William; Jung, Sang Taek; Liu, Yi; Laserson, Jonathan; Chari, Raj; Lee, Je-Hyuk; Bachelet, Ido; Hickey, Brendan; Lieberman-Aiden, Erez; Hanczaruk, Bozena; Simen, Birgitte B.; Egholm, Michael; Koller, Daphne; Georgiou, George; Kleinstein, Steven H.; Church, George M. (National Academy of Sciences (U.S.), 2014-03)
    The adaptive immune system confers protection by generating a diverse repertoire of antibody receptors that are rapidly expanded and contracted in response to specific targets. Next-generation DNA sequencing now provides ...
  • Garland, Carl W.; Iannacchione, G. S. (American Physical Society, 2009-01)
    High-resolution ac calorimetry has been used to study the nematic to smectic-A (N-SmA) phase transition in the liquid crystal octylcyanobiphenyl (8CB) confined in aligned colloidal aerosil gels. A stable and robust nematic ...
  • Zhu, Cong; Byers, Kelsey J.R.P.; McCord, Rachel P.; Shi, Zhenwei; Berger, Michael F.; Newburger, Daniel E.; Saulrieta, Katrina; Smith, Zachary; Shah, Mita V.; Radhakrishnan, Mathangi; Philippakis, Anthony A.; Hu, Yanhui; De Masi, Federico; Pacek, Marcin; Rolfs, Andreas; Murthy, Tal; LaBaer, Joshua; Bulyk, Martha L. (Cold Spring Harbor Laboratory Press, 2009-01)
    Transcription factors (TFs) regulate the expression of genes through sequence-specific interactions with DNA-binding sites. However, despite recent progress in identifying in vivo TF binding sites by microarray readout of ...
  • Aernecke, M.; Jain, Tarun; Liberman, Vladimir; Karnik, Rohit (American Institute of Physics (AIP), 2014-02)
    Nanostencil lithography has a number of distinct benefits that make it an attractive nanofabrication processes, but the inability to fabricate features with nanometer precision has significantly limited its utility. In ...
  • Edwards, Matthew Douglas; Gifford, David K. (BioMed Central Ltd, 2012-04)
    Background: Modern genetics has been transformed by high-throughput sequencing. New experimental designs in model organisms involve analyzing many individuals, pooled and sequenced in groups for increased efficiency. ...
  • Edwards, Matthew Douglas; Gifford, David K. (BioMed Central, 2012-04)
    Background: Modern genetics has been transformed by high-throughput sequencing. New experimental designs in model organisms involve analyzing many individuals, pooled and sequenced in groups for increased efficiency. ...
  • Guo, Yuchun; Mahony, Shaun (Public Library of Science, 2012-08)
    An essential component of genome function is the syntax of genomic regulatory elements that determine how diverse transcription factors interact to orchestrate a program of regulatory control. A precise characterization ...
  • Ren, Y.; Hovenier, J. N.; Higgins, R.; Gao, J. R.; Klapwijk, T. M.; Shi, S. C.; Klein, B.; Reno, J. L.; Kao, Tsung-Yu; Hu, Qing (American Institute of Physics (AIP), 2011-06)
    A frequency tunable terahertz heterodynespectrometer, based on a third-order distributed feedback quantum cascade laser as a local oscillator, has been demonstrated by measuring molecular spectral lines of methanol ...
  • Goossens, Sander; Sabaka, Terence J.; Nicholas, Joseph B.; Lemoine, Frank G.; Rowlands, David D.; Mazarico, Erwan Matias; Neumann, Gregory A.; Smith, David Edmund; Zuber, Maria (American Geophysical Union (AGU), 2014-05)
    We estimated a high-resolution local gravity field model over the south pole of the Moon using data from the Gravity Recovery and Interior Laboratory's extended mission. Our solution consists of adjustments with respect ...
  • Mag Washietl, Stefan; Kheradpour, Pouya; Ernst, Jason; Ward, Lucas D.; Jungreis, Irwin; Rasmussen, Matthew D.; Kellis, Manolis (Nature Publishing Group, 2011-10)
    The comparison of related genomes has emerged as a powerful lens for genome interpretation. Here we report the sequencing and comparative analysis of 29 eutherian genomes. We confirm that at least 5.5% of the human genome ...
  • Reeder, Christopher; Closser, Michael; Poh, Huay Mei; Sandhu, Kuljeet; Wichterle, Hynek; Gifford, David K. (Public Library of Science, 2015-05)
    RNA Polymerase II ChIA-PET data has revealed enhancers that are active in a profiled cell type and the genes that the enhancers regulate through chromatin interactions. The most commonly used computational method for ...
  • Le, Tung Ba Khanh; Imakaev, Maksim Viktorovich; Mirny, Leonid A.; Laub, Michael T. (American Association for the Advancement of Science (AAAS), 2013-10)
    Chromosomes must be highly compacted and organized within cells, but how this is achieved in vivo remains poorly understood. We report the use of chromosome conformation capture coupled with deep sequencing (Hi-C) to map ...
  • Bayro, Marvin J.; Griffin, Robert Guy; Maly, Thorsten; Birkett, Neil R.; Dobson, Christopher M.; MacPhee, Cait E. (American Chemical Society (ACS), 2010-07)
    The SH3 domain of the PI3 kinase (PI3-SH3 or PI3K-SH3) readily aggregates into fibrils in vitro and has served as an important model system in the investigation of the molecular properties and mechanism of formation of ...
  • Harman, Michelle; Li, Xingde; Pitris, Costas; Ghanta, Ravi; Fujimoto, James G.; Stamper, Debra L.; Brezinski, Mark E.; Martin, Scott (BioMed Central Ltd, 2005-01)
    This study demonstrates the first real-time imaging in vivo of human cartilage in normal and osteoarthritic knee joints at a resolution of micrometers, using optical coherence tomography (OCT). This recently developed ...
  • Leeb, Steven B.; Paris, James; Avestruz, Al-Thaddeus; Wichakool, Warit (Institute of Electrical and Electronics Engineers, 2010-02)
    This paper presents a high-resolution, physically-windowed sensor architecture that is well-suited for energy scorekeeping and diagnostic applications. The sensor can track a large-scale main signal while capturing small-scale ...
  • Wichakool, Warit; Paris, James; Avestruz, Al-Thaddeus; Leeb, Steven B. (Institute of Electrical and Electronics Engineers (IEEE), 2010-03)
    This paper presents a high-resolution, physically-windowed sensor architecture that is well-suited for energy scorekeeping and diagnostic applications. The sensor can track a large-scale main signal while capturing small-scale ...
  • Keller, Stefan C.; Casey, Andrew R.; Asplund, Martin; Bessell, Michael S.; Costa, Gary S. Da; Lind, Karin; Marino, Anna F.; Norris, John E.; Schmidt, Brian P.; Tisserand, Patrick; Walsh, Jennifer M.; Yong, David; Yu, Qinsi; Jacobson, Heather; Frebel, Anna L.; Pena, Jose M. (IOP Publishing, 2015-07)
    The SkyMapper Southern Sky Survey is carrying out a search for the most metal-poor stars in the Galaxy. It identifies candidates by way of its unique filter set which allows for estimation of stellar atmospheric parameters. ...
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