Advanced Search
DSpace@MIT

Browsing MIT Open Access Articles by Title

Research and Teaching Output of the MIT Community

Browsing MIT Open Access Articles by Title

Sort by: Order: Results:

  • Wang, Xiaoxin; Kimerling, Lionel C.; Michel, Jurgen; Liu, Jifeng (American Institute of Physics (AIP), 2013-04)
    The recent demonstration of Ge-on-Si diode lasers renews the interest in the unique carrier dynamics of Ge involving both direct (Γ) and indirect (L) valleys. Here, we report a large inherent direct gap optical gain ...
  • Huarte, Maite; Guttman, Mitchell; Feldser, David; Garber, Manuel; Koziol, Magdalena J.; Kenzelmann-Broz, Daniela; Khalil, Ahmad M.; Zuk, Or; Amit, Ido; Rabani, Michal; Attardi, Laura D.; Regev, Aviv; Lander, Eric S.; Rinn, John L.; Jacks, Tyler E. (Elsevier, 2010-08)
    Recently, more than 1000 large intergenic noncoding RNAs (lincRNAs) have been reported. These RNAs are evolutionarily conserved in mammalian genomes and thus presumably function in diverse biological processes. Here, we ...
  • Guttman, Mitchell; Lander, Eric S.; Loewer, Sabine; Cabili, Moran N.; Loh, Yuin-Han; Thomas, Kelly; Park, In Hyun; Garber, Manuel; Curran, Matthew; Onder, Tamer; Agarwal, Suneet; Manos, Philip D.; Datta, Sumon; Schlaeger, Thorsten M.; Daley, George Q.; Rinn, John L. (Nature Publishing Group, 2010-11)
    The conversion of lineage-committed cells to induced pluripotent stem cells (iPSCs) by reprogramming is accompanied by a global remodeling of the epigenome[superscript 1, 2, 3, 4, 5], resulting in altered patterns of gene ...
  • Chen, Xingang; Wang, Yi (American Physical Society, 2010-03)
    We study the slow-roll inflation models, where the inflaton slow-rolls along a trajectory whose orthogonal directions are lifted by potentials with masses of order the Hubble parameter. In these models large non-Gaussianities ...
  • Cassa, Christopher A.; Tong, Mark Y.; Jordan, Daniel M. (Wiley Blackwell, 2013-07)
    It is now affordable to order clinically interpreted whole-genome sequence reports from clinical laboratories. One major component of these reports is derived from the knowledge base of previously identified pathogenic ...
  • Chakrabarty, Deepto; Remillard, Ronald Alan (Springer Science + Business Media B.V., 2012-10)
    High-time-resolution X-ray observations of compact objects provide direct access to strong-field gravity, to the equation of state of ultradense matter and to black hole masses and spins. A 10 m[superscript 2]-class ...
  • Chen, Xingang; Hu, Bin; Huang, Min-xin; Shiu, Gary; Wang, Yi (Institute of Physics Publishing, 2009-08)
    We compute the large scalar four-point correlation functions in general single field inflation models, where the inflaton Lagrangian is an arbitrary function of the inflaton and its first derivative. We find that the leading ...
  • Cocco, S.; De Leonardis, E.; Monasson, R.; Barton, John P. (American Physical Society, 2014-07)
    The mean-field (MF) approximation offers a simple, fast way to infer direct interactions between elements in a network of correlated variables, a common, computationally challenging problem with practical applications in ...
  • Chua, Song-Liang; Lu, Ling; Bravo-Abad, Jorge; Joannopoulos, John D.; Soljačić, Marin; Soljacic, Marin (Optical Society of America, 2014-03)
    By altering the lattice geometry of the photonic crystal (PhC) surface-emitting lasers (PCSELs), we tune the regular lasing band edges of quadratic dispersions to form a single accidental Dirac point of linear dispersion ...
  • Wang, H.; Yu, L.; Lee, Y.-H.; Fang, W.; Hsu, A.; Chin, M.; Dubey, M.; Li, L.-J.; Kong, J.; Herring, Patrick Kenichi; Palacios, Tomas (Institute of Electrical and Electronics Engineers (IEEE), 2012-12)
    2D nanoelectronics based on single-layer MoS[subscript 2] offers great advantages for both conventional and ubiquitous applications. This paper discusses the large-scale CVD growth of single-layer MoS[subscript 2] and ...
  • Wissner-Gross, Zachary D.; Scott, Mark Andrew; Ku, David L.; Ramaswamy, Priya (Royal Society of Chemistry, The, 2010-09)
    During both development and regeneration of the nervous system, neurons display complex growth dynamics, and several neurites compete to become the neuron's single axon. Numerous mathematical and biophysical models have ...
  • Flood, Thomas F.; Gorczyca, Michael; White, Benjamin H.; Ito, Kei; Yoshihara, Motojiro (Genetics Society of America, 2013-08)
    Drosophila is increasingly used for understanding the neural basis of behavior through genetically targeted manipulation of specific neurons. The primary approach in this regard has relied on the suppression of neuronal ...
  • Kellis, Manolis; Bernstein, Bradley E. (BioMed Central Ltd, 2005-03)
    A report on the genomics workshop 'Identification of Functional Elements in Mammalian Genomes', Cold Spring Harbor, New York, 11-13 November 2004.
  • Carlson, Scott M.; Chouinard, Candace R.; Labadorf, Adam; Lam, Carol J.; Schmelzle, Katrin; Fraenkel, Ernest; White, Forest M. (American Association for the Advancement of Science (AAAS), 2011-10)
    The mitogen-activated protein kinase (MAPK) extracellular signal–regulated kinase 2 (ERK2) is ubiquitously expressed in mammalian tissues and is involved in a wide range of biological processes. Although MAPKs have been ...
  • Issa, Elias; Papanastassiou, Alex M.; DiCarlo, James (Society for Neuroscience, 2013-09)
    Maps obtained by functional magnetic resonance imaging (fMRI) are thought to reflect the underlying spatial layout of neural activity. However, previous studies have not been able to directly compare fMRI maps to high-resolution ...
  • Issa, Elias; DiCarlo, James; Papanastassiou, Alex M. (Society for Neuroscience, 2013-09)
    Maps obtained by functional magnetic resonance imaging (fMRI) are thought to reflect the underlying spatial layout of neural activity. However, previous studies have not been able to directly compare fMRI maps to high-resolution ...
  • Lun, Desmond S.; Rockwell, Graham; Guido, Nicholas J.; Baym, Michael Hartmann; Kelner, Jonathan Adam; Berger, Bonnie; Galagan, James E.; Church, George M. (Nature Publishing Group, 2009-08)
    In the past decade, computational methods have been shown to be well suited to unraveling the complex web of metabolic reactions in biological systems. Methods based on flux–balance analysis (FBA) and bi-level optimization ...
  • Gilleland, Cody Lee; Rohde, Christopher Benjamin; Samara, Chrysanthi; Yanik, Mehmet Fatih; Haggarty, Stephen J. (National Academy of Sciences, 2010-10)
    Discovery of molecular mechanisms and chemical compounds that enhance neuronal regeneration can lead to development of therapeutics to combat nervous system injuries and neurodegenerative diseases. By combining high-throughput ...
  • Berke, Allison P.; Vanberghem, Melanie; Graveland-Bikker, Johanna; Kaiser, Liselotte; Steuerwald, Dirk; Cook, Brian L.; Zhang, Shuguang; Vogel, Horst; Pick, Horst; Herlihy, Kara (United States National Academy of Sciences, 2009-05)
    Although understanding of the olfactory system has progressed at the level of downstream receptor signaling and the wiring of olfactory neurons, the system remains poorly understood at the molecular level of the receptors ...
  • Kundaje, Anshul; Marinov, Georgi K.; Park, Peter J.; Wold, Barbara J. (Genetics Society of America, 2013-12)
    ChIP-seq has become the primary method for identifying in vivo protein–DNA interactions on a genome-wide scale, with nearly 800 publications involving the technique appearing in PubMed as of December 2012. Individually and ...
Open Access