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Browsing MIT Open Access Articles by Title

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  • Lippard, Stephen J.; Dhara, Shanta (National Academy of Sciences, 2009-12)
    The unique glycolytic metabolism of most solid tumors, known as the Warburg effect, is associated with resistance to apoptosis that enables cancer cells to survive. Dichloroacetate (DCA) is an anticancer agent that can ...
  • Fletcher, Luke Sebastian; Teller, Seth; Olson, Edwin B.; Moore, David; Kuwata, Yoshiaki; How, Jonathan P.; Leonard, John Joseph; Miller, Isaac; Campbell, Mark; Huttenlocher, Dan; Nathan, Aaron; Kline, Frank-Robert (Springer Berlin / Heidleberg, 2009-11)
    Mid-way through the 2007 DARPA Urban Challenge, MIT’s autonomous Land Rover LR3 ‘Talos’ and Team Cornell’s autonomous Chevrolet Tahoe ‘Skynet’ collided in a low-speed accident, one of the first well-documented collisions ...
  • Nabian, Nashid; Ratti, Carlo; Biderman, Assaf; Grise, Gabriel (Institute of Electrical and Electronics Engineers, 2009-10)
    This paper focuses on guidelines in designing platforms for collective, location-sensitive user generated content, built upon a system that allows for locating mobile subjects within the space. The process of conceptual ...
  • Masters, Barry R.; So, Peter T. C.; Buehler, Christof; Barry, Nicholas; Sutin, Jason D.; Mantulin, William W.; Gratton, Enrico (SPIE, 2004-10)
    Two-photon excitation fluorescence microscopy allows in vivo high-resolution imaging of human skin structure and biochemistry with a penetration depth over 100 μm. The major damage mechanism during two-photon skin imaging ...
  • Graves, William S.; Brown, W.; Kaertner, Franz X.; Moncton, David E. (Elsevier, 2009-09)
    A compact X-ray source based on inverse Compton scattering of a high-power laser on a high-brightness linac beam is described. The facility can operate in two modes: at high (MHz) repetition rate with flux and brilliance ...
  • Yaffe, Michael B.; Brummelkamp, Thijn R.; Reinhardt, Hans; Ostheimer, Gerard Joseph; Gardino, Alexandra Kate; van Vugt, Marcel A. T. M.; Smerdon, Stephen J.; Carr, Steven A.; Lewis, Timothy A.; Pawson, Tony; Li, Jeijin; Keezer, Susan M.; Miao, Hua; Tan, Chris S.; Ong, Shao-En; Linding, Rune (Public Library of Science, 2010-01)
    DNA damage checkpoints arrest cell cycle progression to facilitate DNA repair. The ability to survive genotoxic insults depends not only on the initiation of cell cycle checkpoints but also on checkpoint maintenance. While ...
  • Schneider, Robert J.; Perrin, Douglas P.; Vasilye, Nikolay V.; Marx, Gerald R.; Nido, Pedro J. del; Howe, Robert D. (Institute of Electrical and Electronics Engineers (IEEE), 2010-08)
    The shape of the mitral valve annulus is used in diagnostic and modeling applications, yet methods to accurately and reproducibly delineate the annulus are limited. This paper presents a mitral annulus segmentation algorithm ...
  • Bosecker, C. J.; Krebs, Hermano Igo (Institute of Electrical and Electronics Engineers, 2009-08)
    The ability to walk is important for independent living and when this capacity is affected by neurological injury, gait therapy is the traditional approach to re-train the nervous system. The importance of this problem is ...
  • Long, Phillip D.; Abelson, Harold (Institute of Electrical and Electronics Engineers, 2008-06)
    This paper discusses the institutional framework and the strategic decisions the led the launch of several major major educational technology initiatives at MIT between 1999 and 2003. It describes how MIT’s central ...
  • Clare, Andrew S; Cummings, M. L.; Macbeth, Jamie C.; Clare, Andrew S. (Institute of Electrical and Electronics Engineers (IEEE), 2012-06)
    Advances in autonomy have made it possible to invert the typical operator-to-unmanned vehicle ratio so that a single operator can now control multiple heterogeneous Unmanned Vehicles (UVs). Real-time scheduling and task ...
  • Shuckburgh, Emily; Maze, Guillaume; Ferreira, David; Marshall, John C.; Jones, Helen; Hill, Christopher N. (American Meteorological Society, 2011-01)
    The modulation of air–sea heat fluxes by geostrophic eddies due to the stirring of temperature at the sea surface is discussed and quantified. It is argued that the damping of eddy temperature variance by such air–sea ...
  • Ajoy, Ashok; Cappellaro, Paola (American Physical Society, 2012-04)
    Quantum spin networks can be used to transport information between separated registers in a quantum-information processor. To find a practical implementation, the strict requirements of ideal models for perfect state ...
  • Nagy, Kevin David; Shen, Bo; Jamison, Timothy F.; Jensen, Klavs F. (American Chemical Society (ACS), 2012-01)
    Continuous flow chemistry is being used increasingly; however, without detailed knowledge of reaction engineering, it can be difficult to judge whether dispersion and mixing are important factors on reaction outcome. ...
  • Plotnik, Aaron M.; Shaw, William; Haslem, Brent; Ferguson, Dean; Marchant, David; Bird, Alan; Peterson, James; Greenman, Mark; Burk, Karl; Ip, Katharine; Brown, Steven; Dixon, Deon; Welsh, Dan; Kalscheur, Micah; Margulis, Michael; Albritton, Jon; Pancholi, Kajal; Sisko, Bryan; Williams, Jason; Scott, Hansen; Tansock, Joseph (The International Society for Optical Engineering, 2009-04)
    The Multiple Kill Vehicle (MKV) system, which is being developed by the US Missile Defense Agency (MDA), is a midcourse payload that includes a carrier vehicle and a number of small kill vehicles. During the mission, the ...
  • McKay, Ian (ASME International, 2012-11)
    By combining the aeroelastic and vortex-forced flutter modes of a thin plastic strip, its oscillation frequency can be confined to scale monotonically with fluid velocity. This principle has been used to produce a low-cost, ...
  • Wang, Chenbo; Haeffner, Fredrik; Hoveyda, Amir H.; Schrock, Richard Royce (Wiley Blackwell, 2013-01)
    Olefin metathesis catalysts for controlling the formation of trisubstituted macrocyclic Z alkenes have been developed. The most effective complexes are Mo alkylidenes with a pentafluorophenylimido group and two large ...
  • Tappan, Jacqueline; Mikkelsen, Christine; Driediger, Ken; Cummings, M. L. (Association for Computing Machinery (ACM), 2011-08)
    This research, a collaboration between MIT and ABB/Ventyx, is focused on the development of a mobile interface for field workers in power repair settings and field service delivery. A Human Systems Engineering (HSE) approach ...
  • Wu, Eugene; Balakrishnan, Hari; Cheung, Alvin K.; Sivalingam, Lenin Ravindranth; Madden, Samuel R. (Association for Computing Machinery (ACM), 2013-07)
    Smart-phone applications ("apps") run across a wide range of environmental conditions, locations, and hardware platforms. They are often subject to an array of interactions that are hard or impossible for developers to ...
  • Reben, Alexander James; Paradiso, Joseph A. (Association for Computing Machinery (ACM), 2011)
    Documentaries are typically captured in a very structured way, using teams to film and interview people. We developed an autonomous method for capturing structured cinéma vérité style documentaries through an interactive ...
  • Johansson, M.; Rivera, C.; de Foy, B.; Lei, Wenfang; Song, J.; Zhang, Y.; Galle, B.; Molina, Luisa Tan (European Geosciences Union / Copernicus, 2009-08)
    We here present the results from mobile measurements using two ground-based zenith viewing Differential Optical Absorption Spectroscopy (DOAS) instruments. The measurement was performed in a cross-section of the plume from ...
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