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Browsing MIT Open Access Articles by Title

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  • Zhu, Guangyu; Myint, MyatNoeZin; Ang, Wee Han; Song, Lina; Lippard, Stephen J. (American Association for Cancer Research, 2011-12)
    To overcome drug resistance and reduce the side effects of cisplatin, a widely used antineoplastic agent, major efforts have been made to develop next generation platinum-based anticancer drugs. Because cisplatin–DNA adducts ...
  • Wang, Jianfei; Zens, Timothy; Hu, Juejun; Becla, Piotr; Kimerling, Lionel C.; Agarwal, Anuradha Murthy (American Institute of Physics (AIP), 2012-05)
    In this paper, we present experimental demonstration of a resonant-cavity-enhanced mid-infrared photodetector monolithically fabricated on a silicon substrate. Dual-band detection at 1.6 μm and 3.7 μm is achieved within a ...
  • Liu, Jifeng; Sun, Xiaochen; Cai, Yan; Kimerling, Lionel C.; Michel, Jurgen; Camacho-Aguilera, Rodolfo Ernesto (Institute of Electrical and Electronics Engineers (IEEE), 2010-09)
    We report room temperature Ge-on-Si lasers with direct gap emission at 1590-1610 nm. Modeling of Ge/Si double heterojunction structures, which is supported by experimental results of Ge/Si LEDs, indicates the feasibility ...
  • Unknown author (Institute of Electrical and Electronics Engineers (IEEE), 2008-10)
    We summarize our work on creating substrate platforms, processes, and devices for the monolithic integration of silicon CMOS circuits with III-V optical and electronic devices. Visible LEDs and InP HBTs have been integrated ...
  • Tingley, Peter William (National Academy of Sciences of Ukraine (SIGMA (Symmetry, Integrability, and Geometry: Methods and Application)), 2010-04)
    Recently Fayers introduced a large family of combinatorial realizations of the fundamental crystal B(Λ[subscript 0]) for [^ over sl][subscript n], where the vertices are indexed by certain partitions. He showed that special ...
  • Corbett, Kevin D.; Yip, Calvin K.; Ee, Ly-Sha; Walz, Thomas; Amon, Angelika B.; Harrison, Stephen C. (Elsevier B.V., 2010-08)
    The monopolin complex regulates different types of kinetochore-microtubule attachments in fungi, ensuring sister chromatid co-orientation in Saccharomyces cerevisiae meiosis I and inhibiting merotelic attachment in ...
  • Ashlagi, Itai; Braverman, Mark; Hassidim, Avinatan; Monderer, Dov (Econometric Society, 2010-09)
    Consider an environment with a finite number of alternatives, and agents with private values and quasilinear utility functions. A domain of valuation functions for an agent is a monotonicity domain if every finite-valued ...
  • Colding, Tobias; Minicozzi, William (National Academy of Sciences (U.S.), 2012-08)
    In this expository article, we discuss various monotonicity formulas for parabolic and elliptic operators and explain how the analysis of function spaces and the geometry of the underlining spaces are intertwined. After ...
  • Mukherjee, Sayak; Zhu, Jing; Zikherman, Julie; Parameswaran, Ramya; Kadlecek, Theresa A.; Wang, Qi; Au-Yeung, Byron; Ploegh, Hidde; Kuriyan, John; Das, Jayajit; Weiss, Arthur (American Association for the Advancement of Science, 2013-01)
    The Src and Syk families of kinases are two distinct sets of kinases that play critical roles in initiating membrane-proximal B cell receptor (BCR) signaling. However, unlike in other lymphocytes, such as T cells, the ...
  • Avalos, Ana M.; Bilate, Angelina M.; Witte, Martin D.; Tai, Albert K.; He, Jiang; Frushicheva, Maria P.; Thill, Peter Daniel; Meyer-Wentrup, Friederike; Theile, Christopher S.; Chakraborty, Arup K.; Zhuang, Xiaowei; Ploegh, Hidde (Rockefeller University Press, 2014-02)
    Valency requirements for B cell activation upon antigen encounter are poorly understood. OB1 transnuclear B cells express an IgG1 B cell receptor (BCR) specific for ovalbumin (OVA), the epitope of which can be mimicked ...
  • Silver, David; Veness, Joel; Ng, Kee Siong; Hutter, Marcus; Uther, William (AI Access Foundation, 2011-01)
    This paper introduces a principled approach for the design of a scalable general reinforcement learning agent. Our approach is based on a direct approximation of AIXI, a Bayesian optimality notion for general reinforcement ...
  • Jiang, Fu-Jiun; Kampfer, Florian; Nyfeler, M. (American Physical Society, 2009-07)
    Motivated by the possible mechanism for the pinning of the electronic liquid crystal direction in YBa2Cu3O6.45 [YBa subscript 2 Cu supscript 3 O subscript 6.45] as proposed by Pardini et al. [Phys. Rev. B 78, 024439 (2008)], ...
  • Xu, Zao; Yue, Dick K. P. (Society of Photo-Optical Instrumentation Engineers (SPIE), 2014-02)
    We present a numerical study of the near-surface underwater solar light statistics using the state-of-the-art Monte Carlo radiative transfer (RT) simulations in the coupled atmosphere-ocean system. Advanced variance-reduction ...
  • Hernandez Rivera, Javier; Hoque, Mohammed Ehasanul; Picard, Rosalind W. (Association for Computing Machinery, 2012-08)
    Have you ever wondered whether it's possible to quantitatively measure how friendly or welcoming a community is? Or imagined which parts of the community are happier than others? In this work, we introduce a new technology ...
  • Kirilenko, Andrei; Lo, Andrew W. (American Economic Association, 2013-02)
    Financial markets have undergone a remarkable transformation over the past two decades due to advances in technology. These advances include faster and cheaper computers, greater connectivity among market participants, and ...
  • Perry, Ruth (Oxford University Press, 2009-11)
    The late Grace Paley was one of the great writers of the twentieth century, loved for her humanity and humor and admired for her brilliant, witty, deeply provocative prose fiction. Her literary voice is sui generis – ...
  • Sontag, David; Meshi, Ofer; Jaakkola, Tommi S.; Globerson, Amir (Neural Information Processing Systems Foundation, 2010-12)
    The problem of learning to predict structured labels is of key importance in many applications. However, for general graph structure both learning and inference in this setting are intractable. Here we show that it is ...
  • Eckhardt, Micah Rye; Picard, Rosalind W. (Institute of Electrical and Electronics Engineers, 2009-09)
    Labeling videos for affect content such as facial expression is tedious and time consuming. Researchers often spend significant amounts of time annotating experimental data, or simply lack the time required to label their ...
  • Skow, Bradford (Wiley Blackwell (Blackwell Publishing), 2011-12)
    Anti-haecceitism is the thesis that the universe could not be nonqualitatively different without being qualitatively different. Haecceitism is the denial of anti-haecceitism.1 In “Haecceitism, Anti-Haecceitism, and ...
  • Giambalvo, Vince; Miller, Haynes R. (Mathematical Sciences Publishers, 2011-09)
    The relations of Barratt and Miller are shown to include all relations among the elements P[superscript i]χP[superscript n−i} in the mod p Steenrod algebra, and a minimal set of relations is given.
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