Feldser, David M.; Kostova, Kamena K.; Winslow, Monte Meier; Taylor, Sarah E.; Cashman, Chris; Whittaker, Charles A.; Sanchez-Rivera, Francisco J.; Resnick, Rebecca; Bronson, Roderick T.; Hemann, Michael; Jacks, Tyler E.
(Nature Publishing Group, 2010-11)
Tumorigenesis is a multistep process that results from the sequential accumulation of mutations in key oncogene and tumour suppressor pathways. Personalized cancer therapy that is based on targeting these underlying genetic ...