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Browsing MIT Open Access Articles by Title

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  • O'Donnell, Charles William; Waldispuhl, Jerome; Lis, Mieszko; Halfmann, Randal Arthur; Devadas, Srinivas; Lindquist, Susan; Berger, Bonnie (Oxford University Press, 2011-07)
    Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the specific molecular structure of a fibril can ...
  • Diephuis, Bradford J.; Tearney, Guillermo J.; Liu, Linbo; Chu, Kengyeh K.; Houser, Grace H.; Li, Yao; Wilsterman, Eric J.; Shastry, Suresh; Dierksen, Gregory; Birket, Susan E.; Birket, Susan E.; Byan-Parker, Suzanne; Grizzle, William E.; Sorscher, Eric J.; Rowe, Steven M. (Public Library of Science, 2013-01)
    We demonstrate the use of a high resolution form of optical coherence tomography, termed micro-OCT (μOCT), for investigating the functional microanatomy of airway epithelia. μOCT captures several key parameters governing ...
  • Rahim, Nur Aida Adbul; Pelet, Serge; Kamm, Roger Dale; So, Peter T. C. (SPIE, 2012-03)
    Global algorithms can improve the analysis of fluorescence energy transfer (FRET) measurement based on fluorescence lifetime microscopy. However, global analysis of FRET data is also susceptible to experimental artifacts. ...
  • Yu, Li; Chang, Wen-Yao; Zuo, Kewei; Wang, Jean; Yu, Douglas; Boning, Duane S. (Institute of Electrical and Electronics Engineers (IEEE), 2012-03)
    As continued scaling becomes increasingly difficult, 3D integration with through silicon vias (TSVs) has emerged as a viable solution to achieve higher bandwidth and power efficiency. Mechanical stress induced by thermal ...
  • Waitz, Ian A.; March, Andrew I.; Willcox, Karen E. (American Institute of Aeronautics and Astronautics, 2009-09)
    Significant reductions in environmental impact and operating costs are achievable when both aircraft configuration and operation are considered simultaneously at the early stages of aircraft design. The challenges with ...
  • Gunter, Samantha Joellyn; Perreault, David J.; Suresh, Sindhu; Afridi, Khurram (Institute of Electrical and Electronics Engineers (IEEE), 2013-02)
    Increased penetration of plug-in electric vehicles (PEVs) will necessitate deployment of numerous PEV chargers. Pairing these chargers with renewable distributed generation (DG) and storage can potentially alleviate negative ...
  • Aggarwal, Nancy; Barsotti, Lisa; Biscans, Sebastien; Bodiya, Timothy Paul; Buikema, Aaron; Donovan, Frederick J.; Essick, Reed Clasey; Evans, Matthew J.; Fritschel, Peter K.; Gras, Slawek; Isogai, Tomoki; Katsavounidis, Erotokritos; Lee, P. J.; Libson, Adam; MacInnis, Myron E.; Mason, Kenneth R.; Matichard, Fabrice; Mavalvala, Nergis; Miller, John; Mittleman, Richard K.; Oelker, Eric Glenn; Sankar, S.; Shoemaker, David H.; Vaulin, R.; Vitale, Salvatore; Weiss, Rainer; Wipf, Christopher; Yam, William; Zhang, Fan; Zucker, Michael E. (American Physical Society, 2014-06)
    In this paper we report on a search for short-duration gravitational wave bursts in the frequency range 64 Hz–1792 Hz associated with gamma-ray bursts (GRBs), using data from GEO 600 and one of the LIGO or Virgo detectors. ...
  • Lee, Byungkun; Paradiso, Joseph A.; Aldrich, Matthew Henry; Lee, ByungKun (SPIE, 2011-09)
    The inherent control flexibility implied by solid-state lighting - united with the rich details offered by sensor networks - prompts us to rethink lighting control. In this research, we propose several techniques for ...
  • Rood, Jennifer E.; Leung, Anthony K. L.; Chang, Paul (Springer Science+Business Media, 2011)
    Poly(ADP-ribose) (pADPr) is a posttranslational modification that regulates protein function through two major mechanisms: covalent modification of acceptor proteins and noncovalent binding of proteins to pADPr. pADPr is ...
  • Farrell, Matthew T.; Herr, Hugh M. (Institute of Electrical and Electronics Engineers (IEEE), 2011-08)
    Lower-limb prostheses are rapidly advancing with greater computing power and sensing modalities. This paper is an attempt to begin exploring the trade-off between extrinsic and intrinsic control modalities. In this case, ...
  • Solt, Ken; Cotten, Joseph F.; Cimenser, Aylin; Wong, Kin F. K.; Chemali, Jessica J.; Brown, Emery N. (Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins, 2011-10)
    Background: Although accumulating evidence suggests that arousal pathways in the brain play important roles in emergence from general anesthesia, the roles of monoaminergic arousal circuits are unclear. In this study, the ...
  • Engelward, Bevin P.; Rugo, Rebecca; Mutamba, James Tendai; Yee, Tiffany L.; Chaillet, J. R.; Greenberger, J. S.; Mohan, K. N. (Nature Publishing Group, 2010-11)
    Characterization of the direct effects of DNA-damaging agents shows how DNA lesions lead to specific mutations. Yet, serum from Hiroshima survivors, Chernobyl liquidators and radiotherapy patients can induce a clastogenic ...
  • Nicolaides, Christos; Cueto-Felgueroso, Luis; Gonzalez, Marta C.; Juanes, Ruben (Public Library of Science, 2012-07)
    The spread of infectious diseases at the global scale is mediated by long-range human travel. Our ability to predict the impact of an outbreak on human health requires understanding the spatiotemporal signature of early-time ...
  • Hastings, Daniel E.; Richards, Matthew G.; Shah, Nirav B.; Ross, Adam Michael (American Institute of Aeronautics and Astronautics, 2009-09)
    Survivability engineering is critical for minimizing the impact of disturbances to the operation of space systems. To improve the evaluation of survivability during conceptual design, metrics are proposed for the assessment ...
  • Kelner, Jonathan Adam; Lee, James R.; Price, Gregory N.; Teng, Shang-Hua (Springer Science + Business Media B.V., 2011-08)
    We present a method for proving upper bounds on the eigenvalues of the graph Laplacian. A main step involves choosing an appropriate 'Riemannian' metric to uniformize the geometry of the graph. In many interesting cases, ...
  • Duan, Huigao; Manfrinato, Vitor Riseti; Yang, Joel K. W.; Winston, Donald; Cord, Bryan M.; Berggren, Karl K. (American Vacuum Society (AVS), 2010-11)
    Exploring the resolution limit of electron-beam lithography is of great interest both scientifically and technologically. However, when electron-beam lithography approaches its resolution limit, imaging and metrology of ...
  • Gummadi, Ramakrishna; Balakrishnan, Hari; Seshan, Srinivasan (Institute of Electrical and Electronics Engineers, 2009-01)
    Many licensed and unlicensed frequency bands support heterogeneous wireless networks running different physical and link layer protocols. These networks ldquosharerdquo spectrum, but in an anarchic and arbitrary manner, ...
  • Aiken, A. C.; Foy, B. de; Wiedinmyer, C.; Ulbrich, I. M.; Wehrli, M. N.; Szidat, S.; Prevot, A. S. H.; Noda, J.; Wacker, L.; Volkamer, R.; Fortner, E.; Wang, J.; Laskin, A.; Shutthanandan, V.; Zheng, J.; Zhang, R.; Paredes-Miranda, G.; Arnott, W. P.; Molina, Luisa Tan; Sosa, G.; Querol, X.; Jimenez, J. L.; DeCarlo, P. F. (European Geosciences Union / Copernicus, 2010-06)
    Submicron aerosol was analyzed during the MILAGRO field campaign in March 2006 at the T0 urban supersite in Mexico City with a High-Resolution Aerosol Mass Spectrometer (AMS) and complementary instrumentation. Positive ...
  • Giunchi, Giovanni; Coppi, Bruno (Institute of Electrical and Electronics Engineers, 2010-06)
    A hybrid solution is proposed for the IGNITOR research fusion machine by using of superconducting coils for some poloidal magnets, in association with high field copper magnets for the central solenoid and for the toroidal ...
  • Yao, Weijun; Hahn, Seung-Yong; Iwasa, Yukikazu (Institute of Electrical and Electronics Engineers, 2010-01)
    In this paper, we report our progress in the development of a low cost, liquid-helium-free MgB2 superconducting MRI magnet. Several technical issues related to the construction of such a magnet to operate in persistent ...
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