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Browsing MIT Open Access Articles by Title

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  • Mercier, Patrick P.; Bandyopadhyay, Saurav; Lysaght, Andrew C.; Stankovic, Konstantina M; Chandrakasan, Anantha P.; Stankovic, Konstantina M. (Institute of Electrical and Electronics Engineers (IEEE), 2013-09)
    This paper presents an ultra-low-standby-power radio transmitter that was designed for applications with extreme energy storage and/or energy harvesting constraints. By utilizing aggressive power gating techniques within ...
  • Hirsch, Matthew Waggener; Izadi, Shahram; Raskar, Ramesh; Holtzman, Henry N. (Association for Computing Machinery (ACM), 2013-04)
    We present an 8-dimensional (8D) display that allows glasses-free viewing of 3D imagery, whist capturing and reacting to incident environmental and user controlled light sources. We demonstrate two interactive possibilities ...
  • Chandrakasan, Anantha P.; Bandyopadhyay, Saurav; Neidorff, Bob; Freeman, Dave (Institute of Electrical and Electronics Engineers (IEEE), 2013-02)
    With the advent of reliable, high brightness and high efficacy LEDs, the lighting industry is expected to see a significant growth in the near future. However, for LEDs to completely replace the traditional incandescent ...
  • El-Damak, Dina Reda; Bandyopadhyay, Saurav; Chandrakasan, Anantha P. (Institute of Electrical and Electronics Engineers (IEEE), 2013-02)
    Dynamic Voltage Scaling (DVS) has become one of the standard techniques for energy efficient operation of systems by powering circuit blocks at the minimum voltage that meets the desired performance [1]. Switched Capacitor ...
  • Baker, Tania; Sauer, Robert T.; Abdelhakim, Aliaa H. (National Academy of Sciences (U.S.), 2009-09)
    A hyperstable complex of the tetrameric MuA transposase with recombined DNA must be remodeled to allow subsequent DNA replication. ClpX, a AAA+ enzyme, fulfills this function by unfolding one transpososome subunit. Which ...
  • Calvo, Jennifer; Moroski-Erkul, Catherine A.; Lake, Annabelle; Eichinger, Lindsey Wood; Shah, Dharini; Jhun, Iny; Limsirichai, Prajit; Bronson, Roderick T.; Christiani, David C.; Meira, Lisiane B.; Samson, Leona D. (Public Library of Science, 2013-04)
    Alkylating agents comprise a major class of front-line cancer chemotherapeutic compounds, and while these agents effectively kill tumor cells, they also damage healthy tissues. Although base excision repair (BER) is essential ...
  • Daneshmand, Ali; Mazumder, Aprotim; Allocca, Mariacarmela; Calvo, Jennifer A.; Abolhassani, Nona; Jhun, Iny; Muthupalani, Sureshkumar; Ayata, Cenk; Samson, Leona D.; Ebrahimkhani, Mohammad Reza (National Academy of Sciences (U.S.), 2014-10)
    Inflammation is accompanied by the release of highly reactive oxygen and nitrogen species (RONS) that damage DNA, among other cellular molecules. Base excision repair (BER) is initiated by DNA glycosylases and is crucial ...
  • Marino-Enriquez, Adrian; Zhang, Yi-Xiang; Sioletic, Stefano; Kozakewich, Elena; Grebliunaite, Ruta; Ou, Wen-bin; Sicinska, Ewa; Raut, Chandrajit P.; Demetri, George D.; Perez-Atayde, Antonio R.; Wagner, Andrew J.; Fletcher, Jonathan A.; Fletcher, Christopher D. M.; Look, A. Thomas; Snyder, Eric; Gutierrez, Alejandro (Proceedings of the National Academy of Sciences (PNAS), 2011-09)
    Well-differentiated liposarcoma (WDLPS), one of the most common human sarcomas, is poorly responsive to radiation and chemotherapy, and the lack of animal models suitable for experimental analysis has seriously impeded ...
  • Sasaki, Tomoyuki; Lian, Shanshan; Qi, Jie; Bayliss, Peter E.; Carr, Christopher E.; Johnson, Jennifer L.; Guha, Sujay; Kobler, Patrick; Catz, Sergio D.; Gill, Matthew; Jia, Kailiang; Klionsky, Daniel J.; Kishi, Shuji (Public Library of Science, 2014-06)
    Spinster (Spin) in Drosophila or Spinster homolog 1 (Spns1) in vertebrates is a putative lysosomal H[superscript +]-carbohydrate transporter, which functions at a late stage of autophagy. The Spin/Spns1 defect induces ...
  • Picard, Nathalie; Leslie, Jennifer H.; Trowbridge, Sara Kishi; Subramanian, Jaichandar; Nedivi, Elly; Fagiolini, Michela (Society for Neuroscience, 2014-03)
    During development, experience plays a crucial role in sculpting neuronal connections. Patterned neural activity guides formation of functional neural circuits through the selective stabilization of some synapses and the ...
  • Gipson, Theresa Anne; Housman, David E.; Sathasivam, Kirupa; Neueder, Andreas; Landles, Christian; Benjamin, Agnesska C.; Bondulich, Marie K.; Smith, Donna L.; Faull, Richard L. M.; Roos, Raymund A. C.; Howland, David; Detloff, Peter J.; bates, Gillian P. (National Academy of Sciences (U.S.), 2013-01)
    Huntington disease (HD) is a devastating, late-onset, inherited neurodegenerative disorder that manifests with personality changes, movement disorders, and cognitive decline. It is caused by a CAG repeat expansion in exon ...
  • Sathasivam, Kirupa; Neueder, Andreas; Gipson, Theresa Anne; Landles, Christian; Benjamin, Agnesska C.; Bondulich, Marie K.; Amith, Donna L.; Faull, Richard L. M.; Roos, Raymund A. C.; Howland, David; Detloff, Peter J.; Housman, David E.; Bates, Gillian P. (National Academy of Sciences (U.S.), 2013-01)
    Huntington disease (HD) is a devastating, late-onset, inherited neurodegenerative disorder that manifests with personality changes, movement disorders, and cognitive decline. It is caused by a CAG repeat expansion in exon ...
  • Greenblatt, Wesley H.; Rubenstein, Eric M.; Kreft, Stefan G.; Swanson, Robert; Hochstrasser, Mark (Rockefeller University Press, The, 2012-06)
    Little is known about quality control of proteins that aberrantly or persistently engage the endoplasmic reticulum (ER)-localized translocon en route to membrane localization or the secretory pathway. Hrd1 and Doa10, the ...
  • Ceresoli, Davide; Marzari, Nicola; Lopez, M. G.; Thonhauser, T. (American Physical Society, 2010-05)
    We extend the recently developed converse NMR approach [Thonhauser et al., J. Chem. Phys. 131, 101101 (2009)] such that it can be used in conjunction with norm-conserving, nonlocal pseudopotentials. This extension permits ...
  • Lee, Yueh-Lin; Morgan, Dane (American Physical Society, 2015-05)
    In this paper, we perform a comparative study based on ab initio modeling for perovskite ABO[subscript 3] (001) surfaces and surface defect energetics in order to understand the influence of polarity and redox active Mn ...
  • Kulik, Heather J.; Steeves, Adam H.; Field, Robert W. (Elsevier ScienceDirect, 2009-08)
    Based on high-level ab initio calculations, we predict the existence of a strong 4Σ+–4Σ+ [superscript 4 sigma superscript + - superscript 4 sigma superscript +] optical transition (dav=1.6 D) [(d subscript av = 1.6 D)] ...
  • Pick, A.; Cerjan, A.; Rodriguez, A. W.; Stone, A. D.; Chong, Y. D.; Liu, David; Johnson, Steven G. (American Physical Society, 2015-06)
    We present a multimode laser-linewidth theory for arbitrary cavity structures and geometries that contains nearly all previously known effects and also finds new nonlinear and multimode corrections, e.g., a correction to ...
  • Guttman, Mitchell; Garber, Manuel; Levin, Joshua Z.; Donaghey, Julie; Robinson, James; Adiconis, Xian; Fan, Lin; Koziol, Magdalena J.; Gnirke, Andreas; Nusbaum, Chad; Rinn, John L.; Lander, Eric S.; Regev, Aviv (Nature Publishing Group, 2010-07)
    RNA-Seq provides an unbiased way to study a transcriptome, including both coding and noncoding genes. To date, most RNA-Seq studies have critically depended on existing annotations, and thus focused on expression levels ...
  • Liao, Bolin; Zhou, Jiawei; Qiu, Bo; Chen, Gang; Dresselhaus, Mildred (American Physical Society, 2015-06)
    The monolayer of black phosphorus, or “phosphorene,” has recently emerged as a two-dimensional semiconductor with intriguing highly anisotropic transport properties. Existing calculations of its intrinsic phonon-limited ...
  • Esfarjani, Keivan; Chen, Gang; Mendoza, Jonathan M. (American Institute of Physics (AIP), 2015-05)
    We have computed phonon scattering rates and density of states in silicon germanium alloys using Green's function calculations and density functional theory. This method contrasts with the virtual crystal approximation ...
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