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Browsing MIT Open Access Articles by Title

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  • Zhu, Yuwen; Yao, Sheng; Iliopoulou, Bettina P.; Han, Xue; Augustine, Mathew M.; Xu, Haiying; Phennicie, Ryan T.; Flies, Sarah J.; Broadwater, Megan; Ruff, William; Taube, Janis M.; Zheng, Linghua; Luo, Liqun; Zhu, Gefeng; Chen, Jianzhu; Chen, Lieping (Nature Publishing Group, 2013-06)
    The B7/CD28 family has profound modulatory effects in immune responses and constitutes an important target for the development of novel therapeutic drugs against human diseases. Here we describe a new CD28 homologue (CD28H) ...
  • Zhu, Xuling; Stubbe, JoAnne; Parker, Mackenzie James (American Chemical Society (ACS), 2014-01)
    The class Ib ribonucleotide reductase (RNR) isolated from Bacillus subtilis was recently purified as a 1:1 ratio of NrdE (α) and NrdF (β) subunits and determined to have a dimanganic-tyrosyl radical (Mn[superscript ...
  • Zhang, Yan; Stubbe, JoAnne (American Chemical Society (ACS), 2011-05)
    Bacillus subtilis class Ib ribonucleotide reductase (RNR) catalyzes the conversion of nucleotides to deoxynucleotides, providing the building blocks for DNA replication and repair. It is composed of two proteins: α (NrdE) ...
  • Lee, Catherine Ann; Thomas, Jacob; Grossman, Alan D. (American Society for Microbiology, 2012-04)
    Integrative and conjugative elements (ICEs, also known as conjugative transposons) are mobile elements that are found integrated in a host genome and can excise and transfer to recipient cells via conjugation. ICEs and ...
  • Roccaro, Alvaro; Tomita, H.; Ahlen, S.; Avery, D.; Inglis, A.; Battat, James; Dujmic, D.; Henderson, Shawn Wesley; Fisher, Peter H.; Kaboth, Asher Cunningham; Kohse, G.; Lanza, Richard C.; Monroe, J.; Sciolla, G.; Skvorodnev, N.; Wellenstein, H.; Yamamoto, R. (Elsevier, 2009-07)
    We show data from a new type of detector that can be used to determine the neutron flux, the energy distribution, and the direction of motion neutron for both fast and thermal neutrons. Many neutron detectors are plagued ...
  • Hohm, Olaf; Hull, Chris; Zwiebach, Barton (Springer Berlin / Heidelberg, 2010-07)
    Double field theory describes a massless subsector of closed string theory with both momentum and winding excitations. The gauge algebra is governed by the Courant bracket in certain subsectors of this double field theory. ...
  • Conrad, Janet; Spitz, Joshua B.; Terao, K.; Winslow, Lindley (Elsevier, 2014-05)
    The oscillation results published by the Double Chooz Collaboration in 2011 and 2012 rely on background models substantiated by reactor-on data. In this analysis, we present a background-model-independent measurement of ...
  • Ahlen, S.; Henderson, S.; Inglis, A.; Tomita, H.; Wellenstein, H.; Lopez, Jeremy P.; Dujmic, Denis; Battat, James; Deaconu, Cosmin; Fisher, Peter H.; Kaboth, Asher; Monroe, Jocelyn; Sciolla, Gabriella; Yamamoto, Richard (Elsevier, 2012-08)
    The Dark Matter Time Projection Chamber (DMTPC) collaboration is developing a low pressure gas TPC for detecting Weakly Interacting Massive Particle (WIMP)-nucleon interactions. Optical readout with CCD cameras allows for ...
  • Brown, Scott R.; Eickstedt, Donald (Institute of Electrical and Electronics Engineers, 2010-03)
    In this paper, an innovative hybrid control architecture for real-time control of autonomous robotic vehicles is described as well as its implementation on a commercially available autonomous underwater vehicle (AUV). This ...
  • Ritvo, Harriet (2014)
    Research from a humanist perspective has much to offer in interrogating the social and cultural ramifications of invasion ecologies. The impossibility of securing national boundaries against accidental transfer and the ...
  • Desimone, Robert; Buffalo, Elizabeth A.; Fries, Pascal; Landman, Rogier; Liang, Hualou (National Academy of Sciences, 2010-01)
    The visual processing of behaviorally relevant stimuli is enhanced through top-down attentional feedback. One possibility is that feedback targets early visual areas first and the attentional enhancement builds up at ...
  • Kim, Dennis H. (Annual Reviews, 2013-11)
    The molecular genetic analysis of longevity of Caenorhabditis elegans has yielded fundamental insights into evolutionarily conserved pathways and processes governing the physiology of aging. Recent studies suggest that ...
  • Sanni, Olutoba; Chang, Chien-Yi; Langer, Robert; Davies, Martyn C.; Williams, Philip M.; Williams, Paul; Alexander, Morgan R.; Hook, Andrew L.; Anderson, Daniel Griffith (Wiley Blackwell, 2014-12)
    A new class of material resistant to bacterial attachment has been discovered that is formed from polyacrylates with hydrocarbon pendant groups. In this study, the relationship between the nature of the hydrocarbon moiety ...
  • Brigham, Christopher J.; Kurosawa, Kazuhiko; Rha, ChoKyun; Sinskey, Anthony J. (OMICS Publishing Group, 2011-12)
    PhaR from Paracoccus denitrificans functions as a repressor or autoregulator of the expression of genes encoding phasin protein (PhaP) and PhaR itself, both of which are components of polyhydroxyalkanoate (PHA) granules ...
  • Chao, Hui Xiao; Artemova, Tatiana; Gore, Jeff; Yurtsev, Eugene; Datta, Manoshi Sen (Nature Publishing Group, 2013-08)
    Inactivation of β‐lactam antibiotics by resistant bacteria is a ‘cooperative’ behavior that may allow sensitive bacteria to survive antibiotic treatment. However, the factors that determine the fraction of resistant cells ...
  • Stocker, Roman; Seymour, Justin R.; Ahmed, Tanvir (Oxford University Press, 2009-10)
    Marine bacteria exhibit positive chemotactic responses to the extracellular exudates of the toxic phytoplankton Heterosigma akashiwo. In the environment, this will support bacteria–algae associations with potential ...
  • Friedlander, Ronn Samuel; Vlamakis, Hera; Kim, Philseok; Khan, Mughees; Kolter, Roberto; Aizenberg, Joanna (National Academy of Sciences (U.S.), 2013-03)
    Biofilms, surface-bound communities of microbes, are economically and medically important due to their pathogenic and obstructive properties. Among the numerous strategies to prevent bacterial adhesion and subsequent biofilm ...
  • Gareau, Melanie G.; Wine, Eytan; Rodrigues, David M.; Cho, Joon Ho; Whary, Mark T.; Philpott, Dana J.; MacQueen, Glenda; Sherman, Philip M. (BMJ Publishing, 2010-10)
    Background: The brain–gut axis is a key regulator of normal intestinal physiology; for example, psychological stress is linked to altered gut barrier function, development of food allergies and changes in behaviour. Whether ...
  • Pacis, Alain; Tailleux, Ludovic; Morin, Alexander M.; Lambourne, John; MacIsaac, Julia L.; Yotova, Vania; Dumaine, Anne; Danckaert, Anne; Luca, Francesca; Grenier, Jean-Christophe; Hansen, Kasper D.; Gicquel, Brigitte; Yu, Miao; He, Chuan; Tung, Jenny; Pastinen, Tomi; Kobor, Michael S.; Pique-Regi, Roger; Gilad, Yoav; Barreiro, Luis B.; Pai, Athma A. (Cold Spring Harbor Laboratory Press, 2015-09)
    DNA methylation is an epigenetic mark thought to be robust to environmental perturbations on a short time scale. Here, we challenge that view by demonstrating that the infection of human dendritic cells (DCs) with a live ...
  • Marcos; Fu, Henry C.; Powers, Thomas R.; Stocker, Roman (National Academy of Sciences (U.S.), 2012-03)
    The motility of organisms is often directed in response to environmental stimuli. Rheotaxis is the directed movement resulting from fluid velocity gradients, long studied in fish, aquatic invertebrates, and spermatozoa. ...
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