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Browsing MIT Open Access Articles by Title

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  • An i2b2-based, generalizable, open source, self-scaling chronic disease registry 
    Natter, Marc D.; Quan, Justin; Ortiz, David M.; Bousvaros, Athos; Ilowite, Norman T.; Inman, Christi J.; Marsolo, Keith; McMurry, Andrew J.; Sandborg, Christy I.; Schanberg, Laura E.; Wallace, Carol A.; Warren, Robert W.; Weber, Griffin M.; Mandl, Kenneth D. (BMJ Publishing Group, 2012-06)
    Objective: Registries are a well-established mechanism for obtaining high quality, disease-specific data, but are often highly project-specific in their design, implementation, and policies for data use. In contrast to the ...
  • The IBEX background monitor 
    Crew, Geoffrey B.; Allegrini, F.; Demkee, D.; Funsten, H. O.; McComas, D. J.; Randol, B.; Rodriguez, B.; Schwadron, N. A.; Valek, P.; Weidner, S. (Springer Netherlands, 2008-10)
    The IBEX Background Monitor (IBaM) provides a small and lightweight method for independently measuring IBEX’s high-energy proton background by integrating the flux of >~14 keV protons over a ~7° conical FOV. The IBaM is ...
  • The IbpA and IbpB small heat-shock proteins are substrates of the AAA plus Lon protease 
    Bissonnette, Sarah A.; Rivera Rivera, Izarys; Sauer, Robert T.; Baker, Tania (Blackwell Scientific Publications, 2010-02)
    Small heat-shock proteins (sHSPs) are a widely conserved family of molecular chaperones, all containing a conserved α-crystallin domain flanked by variable N- and C-terminal tails. We report that IbpA and IbpB, the sHSPs ...
  • iCalm: Measuring electrodermal activity in almost any setting 
    Hedman, Elliott Bruce; Wilder-Smith, Oliver; Goodwin, Matthew; Poh, Ming-Zher; Fletcher, Richard Ribon; Picard, Rosalind W. (Institute of Electrical and Electronics Engineers, 2009-12)
    The iCalm sensor is a wireless, wearable, washable wristband that can measure electrodermal activity and physical activity in almost any natural setting. This platform has many applications including health monitoring for ...
  • iCalm: Wearable Sensor and Network Architecture for Wirelessly Communicating and Logging Autonomic Activity 
    Dobson, Kelly; Fletcher, Richard Ribon; Goodwin, Matthew; Eydgahi, Hoda; Wilder-Smith, Oliver; Fernholz, David; Kuboyama, Yuta; Hedman, Elliott Bruce; Poh, Ming-Zher; Picard, Rosalind W. (Institute of Electrical and Electronics Engineers (IEEE), 2010-03)
    Widespread use of affective sensing in healthcare applications has been limited due to several practical factors, such as lack of comfortable wearable sensors, lack of wireless standards, and lack of low-power affordable ...
  • Icelandic Control Is Not A-Movement: The Case from Case 
    Landau, Idan; Bobaljik, Jonathan David (MIT Press, 2009-12)
    A rich literature on Icelandic syntax has established that infinitival complements of obligatory control verbs constitute a case assignment domain independent from the matrix clause, and in this differ systematically from ...
  • Ice nucleation and droplet formation by bare and coated soot particles 
    Friedman, Beth; Kulkarni, Gourihar; Beránek, Josef; Zelenyuk, Alla; Thornton, Joel A.; Cziczo, Daniel James (American Geophysical Union (AGU), 2011-09)
    We have studied ice formation at temperatures relevant to homogeneous and heterogeneous ice nucleation, as well as droplet activation and hygroscopicity, of soot particles of variable size and composition. Coatings of ...
  • IcLQG: Combining local and global optimization for control in information space 
    Roy, Nicholas; Huynh, Vu Anh (Institute of Electrical and Electronics Engineers, 2009-07)
    When a mobile robot does not have perfect knowledge of its position, conventional controllers can experience failures such as collisions because the uncertainty of the position is not considered in choosing control actions. ...
  • ICRF Mode Conversion Flow Drive on Alcator C-Mod and Projections to Other Tokamaks 
    Lin, Yijun; Rice, John E.; Wukitch, Stephen James; Greenwald, Martin J.; Hubbard, Amanda E.; Ince-Cushman, Alexander; Lin, Liang; Marmar, Earl S.; Porkolab, Miklos; Reinke, Matthew Logan; Tsujii, Naoto; Wright, John C. (American Institute of Physics, 2009-11)
    Plasma flow drive via ICRF mode conversion (MC) has been demonstrated on Alcator C-Mod. The toroidal rotation in these D([superscript 3]He) MC plasmas is typically more than twice above the empirically determined intrinsic ...
  • Ideas for the Future of the Is Field 
    Davis, Gordon B.; Gray, Paul; Madnick, Stuart E.; Nunamaker, Jay F.; Sprague, Ralph; Whinston, Andrew (Association for Computing Machinery, 2010-12)
    Information systems as a field of intellectual inquiry is now approximately 50 years old. It has many achievements and extensive research to its credit and has established a large group of researchers and experts worldwide. ...
  • Identification and characterization of receptor-specific peptides for siRNA delivery 
    Ren, Yin; Hauert, Sabine; Lo, Justin H.; Bhatia, Sangeeta N. (American Chemical Society (ACS), 2012-08)
    Tumor-targeted delivery of siRNA remains a major barrier in fully realizing the therapeutic potential of RNA interference. While cell-penetrating peptides (CPP) are promising siRNA carrier candidates, they are universal ...
  • Identification and Estimation of a Discrete Game of Complete Information 
    Bajari, Patrick; Hong, Han; Ryan, Stephen (Econometric Society / Wiley, 2010-09)
    We discuss the identification and estimation of discrete games of complete information. Following Bresnahan and Reiss (1990, 1991), a discrete game is a generalization of a standard discrete choice model where utility ...
  • Identification and Estimation of Triangular Simultaneous Equations Models Without Additivity 
    Imbens, Guido W.; Newey, Whitney K. (Econometric Society, 2009-10)
    This paper uses control variables to identify and estimate models with nonseparable, multidimensional disturbances. Triangular simultaneous equations models are considered, with instruments and disturbances that are ...
  • Identification and Functional Validation of the Novel Antimalarial Resistance Locus PF10_0355 in Plasmodium falciparum 
    Tyne, Daria Van; Angelino, Elaine; Barnes, Kayla G.; Rosen, David M.; Lukens, Amanda K.; Daniels, Rachel F.; Milner, Danny A., Jr.; Becker, Justin S.; Yamins, Daniel; Ndiaye, Daouda; Sarr, Ousmane; Mboup, Souleymane; Happi, Christian; Furlotte, Nicholas A.; Eskin, Eleazar; Kang, Hyun Min; Hartl, Daniel L.; Park, Daniel J.; Schaffner, Stephen F.; Neafsey, Daniel E.; Cortese, Joseph F.; Daniels, Rachel F.; Johnson, Charles A.; Shlyakhter, Ilya; Grossman, Sharon Rachel; Karlsson, Elinor K.; Birren, Bruce W.; Wiegand, Roger C.; Lander, Eric S.; Wirth, Dyann F.; Volkman, Sarah K.; Sabeti, Pardis C. (Public Library of Science, 2011-04)
    The Plasmodium falciparum parasite's ability to adapt to environmental pressures, such as the human immune system and antimalarial drugs, makes malaria an enduring burden to public health. Understanding the genetic basis ...
  • Identification and Structural Analysis of a Novel Carboxysome Shell Protein with Implications for Metabolite Transport 
    Klein, Michael G.; Zwart, Peter; Bagby, Sarah C.; Cai, Fei; Chisholm, Sallie (Penny); Heinhorst, Sabine; Cannon, Gordon C.; Kerfeld, Cheryl A. (Elsevier, 2009-09)
    Bacterial microcompartments (BMCs) are polyhedral bodies, composed entirely of proteins, that function as organelles in bacteria; they promote subcellular processes by encapsulating and co-localizing targeted enzymes with ...
  • Identification of a methylase required for 2-methylhopanoid production implications for the interpretation of sedimentary hopanes 
    Welander, Paula V.; Coleman, Maureen L.; Sessions, Alex L.; Summons, Roger Everett; Newman, Dianne K. (National Academy of Sciences, 2010-04)
    The rise of atmospheric oxygen has driven environmental change and biological evolution throughout much of Earth’s history and was enabled by the evolution of oxygenic photosynthesis in the cyanobacteria. Dating this ...
  • Identification of A Population of X-ray-emitting Massive Stars in the Galactic Plane 
    Anderson, Gemma E.; Gaensler, B. M.; Kaplan, David L.; Posselt, Bettina; Slane, Patrick O.; Murray, Stephen S.; Mauerhan, Jon C.; Benjamin, Robert A.; Brogan, Crystal L.; Chakrabarty, Deepto; Drake, Jeremy J.; Drew, Janet E.; Grindlay, Jonathan E.; Hong, Jaesub; Lazio, Joseph W.; Lee, Julia C.; Steeghs, Danny T. H.; van Kerkwijk, Marten H. (Institute of Physics Publishing, 2011-01)
    We present X-ray, infrared, optical, and radio observations of four previously unidentified Galactic plane X-ray sources: AX J163252-4746, AX J184738-0156, AX J144701-5919, and AX J144547-5931. Detection of each source ...
  • Identification of avian W-linked contigs by short-read sequencing 
    Chen, Nancy; Bellott, Daniel W.; Page, David C; Clark, Andrew G (BioMed Central Ltd, 2012-05)
    Background: The female-specific W chromosomes and male-specific Y chromosomes have proven difficult to assemble with whole-genome shotgun methods, creating a demand for new approaches to identify sequence contigs specific ...
  • Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays 
    Reinke, Aaron Wade; Grigoryan, Gevorg; Keating, Amy E. (American Chemical Society, 2010-03)
    Basic-region leucine-zipper transcription factors (bZIPs) contain a segment rich in basic amino acids that can bind DNA, followed by a leucine zipper that can interact with other leucine zippers to form coiled-coil homo- ...
  • Identification of Genomic Regions Associated with Phenotypic Variation between Dog Breeds using Selection Mapping 
    Vaysse, Amaury; Ratnakumar, Abhirami; Derrien, Thomas; Axelsson, Erik; Pielberg, Gerli Rosengren; Fall, Tove; Seppälä, Eija H.; Hansen, Mark S. T.; Lawley, Cindy T.; Bannasch, Danika; Vilà, Carles; Lohi, Hannes; Galibert, Francis; Fredholm, Merete; Häggström, Jens; Hedhammar, Åke; André, Catherine; Hitte, Christophe; Webster, Matthew T.; Sigurdsson, Snaevar; Karlsson, Elinor K.; Lindblad-Toh, Kerstin (Public Library of Science, 2011-10)
    The extraordinary phenotypic diversity of dog breeds has been sculpted by a unique population history accompanied by selection for novel and desirable traits. Here we perform a comprehensive analysis using multiple test ...
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