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Browsing MIT Open Access Articles by Title

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  • Conrad, Janet; Fisher, Peter H.; Formaggio, Joseph A.; Karagiorgi, Georgia Stelios; Milner, Richard G.; Yamamoto, Richard K. (World Scientific, 2010-01)
    We extend the physics case for a new high-energy, ultra-high statistics neutrino scattering experiment, NuSOnG (Neutrino Scattering On Glass) to address a variety of issues including precision QCD measurements, extraction ...
  • Xu, Shuoyu; Wang, Yan; Tai, Dean C.S.; Wang, Shi; Cheng, Chee Leong; Peng, Qiwen; Yan, Jie; Chen, Yongpeng; Sun, Jian; Liang, Xieer; Zhu, Youfu; Welsch, Roy E.; Wee, Aileen; Hou, Jinlin; Yu, Hanry; Rajapakse, Jagath; So, Peter T. C. (Elsevier, 2014-02)
    Background & Aims: There is increasing need for accurate assessment of liver fibrosis/cirrhosis. We aimed to develop qFibrosis, a fully-automated assessment method combining quantification of histopathological architectural ...
  • Supran, Geoffrey James Sasaji; Shirasaki, Yasuhiro; Song, Katherine Wei; Caruge, Jean-Michel; Kazlas, Peter T.; Coe-Sullivan, Seth; Andrew, Trisha L.; Bawendi, Moungi G.; Bulovic, Vladimir (Cambridge University Press (Materials Research Society), 2013-09)
    The mainstream commercialization of colloidal quantum dots (QDs) for light-emitting applications has begun: Sony televisions emitting QD-enhanced colors are now on sale. The bright and uniquely size-tunable colors of ...
  • Nair, Prashant; Lindquist, Susan (National Academy of Sciences of the United States of America, 2011-11)
    Prions defy molecular biology’s central dogma. Misfolded proteins that self-perpetuate, prions were first isolated in the early 1980s as the cause of a fatal sheep disease called scrapie. Since then, prions have been ...
  • Glassman, Elena L.; Tedrake, Russell Louis (Institute of Electrical and Electronics Engineers (IEEE), 2010-07)
    Kinodynamic planning algorithms like Rapidly-Exploring Randomized Trees (RRTs) hold the promise of finding feasible trajectories for rich dynamical systems with complex, nonconvex constraints. In practice, these algorithms ...
  • Park, Hae won; Chuah, Meng Yee; Kim, Sangbae (Institute of Electrical and Electronics Engineers (IEEE), 2014-09)
    This paper introduces a bounding gait control algorithm that allows a successful implementation of duty cycle modulation in the MIT Cheetah 2. Instead of controlling leg stiffness to emulate a ‘springy leg’ inspired from ...
  • Zhong, Y.; Shah, Devavrat; Tsitsiklis, John N. (Institute of Mathematical Statistics, 2014-02)
    We consider a flow-level model of a network operating under an α-fair bandwidth sharing policy (with α > 0) proposed by Roberts and Massoulié [Telecomunication Systems 15 (2000) 185–201]. This is a probabilistic model that ...
  • Shah, Devavrat; Tsitsiklis, John N.; Zhong, Yuan (Association for Computing Machinery, 2010-06)
    We consider a switched network, a fairly general constrained queueing network model that has been used successfully to model the detailed packet-level dynamics in communication networks, such as input-queued switches ...
  • Eggleston, Karen N; Shah, Nilay D; Smith, Steven A; Berndt, Ernst R.; Newhouse, Joseph P. (American Economic Association, 2011-05)
    Although US health care expenditures reached 17.6 percent of GDP in 2009, quality measurement in this important service sector remains limited. Studying quality changes associated with 11 years of health care for patients ...
  • Misailovic, Sasa; Sidiroglou, Stylianos; Hoffmann, Henry Christian; Rinard, Martin C. (Association for Computing Machinery, 2010-05)
    Many computations exhibit a trade off between execution time and quality of service. A video encoder, for example, can often encode frames more quickly if it is given the freedom to produce slightly lower quality video. A ...
  • Martello, Rita; Mangerich, Aswin; Sass, Sabine; Dedon, Peter C.; Burkle, Alexander (American Chemical Society (ACS), 2013-04)
    Poly(ADP-ribosyl)ation is an essential post-translational modification with the biopolymer poly(ADP-ribose) (PAR). The reaction is catalyzed by poly(ADP-ribose) polymerases (PARPs) and plays key roles in cellular physiology ...
  • Szell, Michael; Thurner, Stefan; Klimek, Peter; Duftschmid, Georg; Endel, Gottfried; Kautzky-Willer, Alexandra; Kasper, David C. (National Academy of Sciences (U.S.), 2013-03)
    Based on a unique dataset comprising all 325,000 Austrian patients that were under pharmaceutical treatment for diabetes during 2006 and 2007, we measured the excess risk of developing diabetes triggered by undernourishment ...
  • Mortensen, Luke J.; Levy, Oren; Phillips, Joseph P.; Stratton, Tara; Triana, Brian; Ruiz, Juan P.; Gu, Fangqi; Lin, Charles P.; Karp, Jeffrey Michael (Public Library of Science, 2013-10)
    The ability to deliver cells to appropriate target tissues is a prerequisite for successful cell-based therapy. To optimize cell therapy it is therefore necessary to develop a robust method of in vivo cell delivery ...
  • Zhao, Lei; Whiteaker, Jeffrey R.; Pope, Matthew E.; Kuhn, Eric; Jackson, Angela; Anderson, N. Leigh; Pearson, Terry W.; Carr, Steven A.; Paulovich, Amanda G. (MyJoVE Corporation, 2011-07)
    There is a great need for quantitative assays in measuring proteins. Traditional sandwich immunoassays, largely considered the gold standard in quantitation, are associated with a high cost, long lead time, and are fraught ...
  • Chan, Wan Simon; Chen, Bingzi; Wang, Lianrong; Taghizadeh, Koli; Demott, Michael S.; Dedon, Peter C. (American Chemical Society, 2010-04)
    The oxidation of 2-deoxyribose in DNA has emerged as a critical determinant of the cellular toxicity of oxidative damage to DNA, with oxidation of each carbon producing a unique spectrum of electrophilic products. We have ...
  • Liao, K.-J.; Tagaris, E.; Manomaiphiboon, K.; Wang, Chien; Woo, J.-H.; Amar, P.; He, S.; Russell, A. G. (European Geosciences Union, 2009-02)
    Uncertainties in calculated impacts of climate forecasts on future regional air quality are investigated using downscaled MM5 meteorological fields from the NASA GISS and MIT IGSM global models and the CMAQ model in 2050 ...
  • Cai, PingGen; Mizutani, Yusuke; Tsuchiya, Masahiro; Maloney, John M.; Fabry, Ben; Van Vliet, Krystyn J.; Okajima, Takaharu; Maloney, John M.; Van Vliet, Krystyn J. (Elsevier, 2013-09)
    Among individual cells of the same source and type, the complex shear modulus G[subscript ∗] exhibits a large log-normal distribution that is the result of spatial, temporal, and intrinsic variations. Such large distributions ...
  • Gusev, Alexander; Bhatia, Gaurav; Zaitlen, Noah; Vilhjalmsson, Bjarni J.; Stahl, Eli A.; Gregersen, Peter K.; Worthington, Jane; Klareskog, Lars; Raychaudhuri, Soumya; Plenge, Robert M.; Pasaniuc, Bogdan; Price, Alkes L.; Diogo, Dorothee (Public Library of Science, 2013-12)
    Recent work has shown that much of the missing heritability of complex traits can be resolved by estimates of heritability explained by all genotyped SNPs. However, it is currently unknown how much heritability is missing ...
  • Jha, Birendra; Cueto-Felgueroso, Luis; Juanes, Ruben (American Physical Society (APS), 2011-12)
    Viscous fingering is a well-known hydrodynamic instability that sets in when a less viscous fluid displaces a more viscous fluid. When the two fluids are miscible, viscous fingering introduces disorder in the velocity field ...
  • Sung, Phil; Syed, Zeeshan; Guttag, John V. (Institute of Electrical and Electronics Engineers, 2009-04)
    This paper examines strategies to quantify differences in the morphology of time series while accounting for time skew in the observed data. We adapt four measures originally designed for signal shape comparison: Dynamic ...
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