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Browsing MIT Open Access Articles by Title
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(American Economic Association, 2012-02)For political and practical reasons, environmental regulations sometimes treat point-source polluters, such as power plants, differently from mobile-source polluters, such as vehicles. This paper measures the extent of ...
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(Wiley Blackwell, 2013-07)A sacrificial-post templating method is presented for directing block copolymer self-assembly to form nanostructures consisting of monolayers and bilayers of microdomains. In this approach, the topographical post template ...
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(Institute of Electrical and Electronics Engineers, 2013-05)A minimax metaconverse has recently been proposed as a simultaneous generalization of a number of classical results and a tool for the nonasymptotic analysis. In this paper, it is shown that the order of optimizing the ...
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(Wiley Blackwell, 2011-03)Safer flow: The synthesis of 5-substituted tetrazoles in flow (see scheme) is safe, efficient, scalable, requires no metal promoter, and uses a near-equimolar amount of NaN[subscript 3], yet nonetheless displays a broad ...
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(Institute of Electrical and Electronics Engineers (IEEE), 2009-08)Although fall is a rare event in the life of a humanoid robot, we must be prepared for it because its consequences are serious. In this paper we present a fall strategy which rapidly modifies the robot's fall direction in ...
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(Elsevier, 2013-12)Many urban designers and researchers argue that walkable urban environments can encourage older residents’ walking activities that benefit their physical health. However, walking also exposes older adults to safety risks, ...
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(Elsevier, 2013-05)Background The nuclear transcription factor c-Jun is preferentially expressed in basal-cell carcinoma. Dz13 is a deoxyribozyme that targets JUN messenger RNA and has inhibited the growth of a range of tumours in mice. We ...
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(Institute of Electrical and Electronics Engineers, 2011-12)In this paper, we consider the safety control problem for hidden mode hybrid systems (HMHSs), which are a special class of hybrid automata in which the mode is not available for control. For these systems, safety control ...
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(Institute of Electrical and Electronics Engineers, 2011-12)This paper is concerned with safety control of systems with imperfect state information and disturbance input. Specifically, we consider the class of systems whose dynamics preserve a partial ordering. We provide necessary ...
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(Institute of Electrical and Electronics Engineers, 2010-03)Too often, systems are designed and then an attempt is made to add safety features or to prove that the design is safe after the fact. Safety has to be designed into a system from the start-it cannot be effectively added ...
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(Institute of Electrical and Electronics Engineers (IEEE), 2011-09)In this article, we have illustrated the application of a formal hybrid control approach to design semiautonomous multivehicle systems that are guaranteed to be safe. Our experimental results illustrate that, in a structured ...
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(National Academy of Sciences (U.S.), 2014-03)Rett syndrome (RTT) is a severe X-linked neurodevelopmental disorder mainly affecting females and is associated with mutations in MECP2, the gene encoding methyl CpG-binding protein 2. Mouse models suggest that recombinant ...
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(Springer Science + Business Media B.V., 2012-03)This essay explores the question of how to be good. My starting point is a thesis about moral worth that I’ve defended in the past: roughly, that an action is morally worthy if and only it is performed for the reasons ...
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(Co-Action Publishing, 2015-12)Mucus forms a protective coating on wet epithelial surfaces throughout the body that houses the microbiota and plays a key role in host defense. Mucins, the primary structural components of mucus that creates its viscoelastic ...
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(Nature Publishing Group, 2013-08)Hox genes controlling motor neuron subtype identity are expressed in rostrocaudal patterns that are spatially and temporally collinear with their chromosomal organization. Here we demonstrate that Hox chromatin is subdivided ...
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(Royal Society of Chemistry, 2012-09)The rapid development of high throughput biotechnologies has led to an onslaught of data describing genetic perturbations and changes in mRNA and protein levels in the cell. Because each assay provides a one-dimensional ...
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(Oxford University Press, 2014-11)Motivation: High-throughput datasets such as genetic screens, mRNA expression assays and global phospho-proteomic experiments are often difficult to interpret due to inherent noise in each experimental system. Computational ...
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(Institute of Electrical and Electronics Engineers (IEEE), 2011-04)The method of interval estimation (MIE) provides a strategy for mean squared error (MSE) prediction of algorithm performance at low signal-to-noise ratios (SNR) below estimation threshold where asymptotic predictions fail. ...
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(Institute of Physics/American Astronomical Society, 2009-08)We conduct a search for radio stars by combining radio and optical data from the FIRST survey and the Sloan Digital Sky Survey (SDSS). The faint limit of SDSS makes possible a homogeneous search for radio emission from ...
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(Institute of Electrical and Electronics Engineers (IEEE), 2012-12)In this paper, the filtering problem for a large class of continuous-time, continuous-state stochastic dynamical systems is considered. Inspired by recent advances in asymptotically-optimal sampling-based motion planning ...
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