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Browsing MIT Open Access Articles by Title

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  • Kosuri, Sriram; Endy, Drew; Kelly, Jason R. (BioMed Central Ltd, 2007-12)
    Background Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavior. Given our current understanding of gene ...
  • Mazzini, Francesco; Kettler, Daniel; Dubowsky, Steven; Guerrero, Julio (Institute of Electrical and Electronics Engineers, 2009-12)
    World oil demand and advanced oil recovery techniques have made it economically attractive to rehabilitate previously abandoned oil wells. This requires relatively fast mapping of the shape and location of the down-hole ...
  • Soljacic, Marin; Karalis, Aristeidis; Joannopoulos, John D. (Society of Photo-Optical Instrumentation Engineers, 2009-02)
    A new physical mechanism enabling simultaneous cancellation of group-velocity and attenuation dispersion to extremely high orders for subwavelength light of any small positive, negative or zero value of the group velocity ...
  • Bermel, Peter A.; Ghebrebrhan, Michael; Harradon, Michael R.; Yeng, YiXiang; Celanovic, Ivan; Joannopoulos, John D.; Soljacic, Marin (Springer, 2011-10)
    Selective solar absorbers generally have limited effectiveness in unconcentrated sunlight, because of reradiation losses over a broad range of wavelengths and angles. However, metamaterials offer the potential to limit ...
  • Ghebrebrhan, Michael; Bermel, Peter A.; Yeng, YiXiang; Celanovic, Ivan; Soljacic, Marin; Joannopoulos, John D. (American Physical Society, 2011-03)
    We develop a model for predicting the thermal emission spectrum of a two-dimensional metallic photonic crystal for arbitrary angles based on coupled-mode theory. Calculating the appropriate coupled-mode parameters over a ...
  • Rinard, Martin C.; Ganesh, Vijay; Leek, Tim (Institute of Electrical and Electronics Engineers, 2009-06)
    We present a new automated white box fuzzing technique and a tool, BuzzFuzz, that implements this technique. Unlike standard fuzzing techniques, which randomly change parts of the input file with little or no information ...
  • Hare, Caspar (Oxford University Press, 2010-01)
    Sometimes I lack all-things-considered preferences between items. Sometimes this attitude is insensitive to mild sweetening. There are items A, A+, B, B+, such that, all things considered, I have no preference between A ...
  • Sanjana, Neville E.; Cong, Le; Zhou, Yang; Cunniff, Margaret Mary; Feng, Guoping; Zhang, Feng (Nature Publishing Group, 2012-01)
    Transcription activator-like effectors (TALEs) are a class of naturally occurring DNA-binding proteins found in the plant pathogen Xanthomonas sp. The DNA-binding domain of each TALE consists of tandem 34–amino acid repeat ...
  • Adams, E. Eric; Peterson, Charles H.; Anderson, Sean S.; Cherr, Gary N.; Ambrose, Richard F.; Anghera, Shelly; Bay, Steven; Blum, Michael; Taylor, Caz M.; Condon, Robert; Graham, Monty; Dean, Thomas A.; Guzy, Michael; Hampton, Stephanie; Joye, Samantha; Lambrinos, John; Mate, Bruce; Meffert, Douglas; Somasundaran, Ponisseril; Spies, Robert B.; Tjeerdema, Ronald; Powers, Sean P. (University of California Press, 2012-05)
    The 2010 Deepwater Horizon oil release posed the challenges of two types of spill: a familiar spill characterized by buoyant oil, fouling and killing organisms at the sea surface and eventually grounding on and damaging ...
  • Dhar, Shanta; Kolishetti, Nagesh; Lippard, Stephen J.; Farokhzad, Omid C. (National Academy of Sciences (U.S.), 2011-01)
    Targeted delivery and controlled release of inactive platinum (Pt) prodrugs may offer a new approach to improve the efficacy and tolerability of the Pt family of drugs, which are used to treat 50% of all cancers today. ...
  • Raman, Rahul; Sasisekharan, Ram; Bachelet, Ido; Bulmera, Mark S.; Rosengaus, Rebeca B. (United States National Academy of Sciences, 2009-04)
    Insect pests such as termites cause damages to crops and man-made structures estimated at over $30 billion per year, imposing a global challenge for the human economy. Here, we report a strategy for compromising insect ...
  • Vander Heiden, Matthew G. (Nature Publishing Group, 2011-09)
    Genetic events in cancer activate signalling pathways that alter cell metabolism. Clinical evidence has linked cell metabolism with cancer outcomes. Together, these observations have raised interest in targeting metabolic ...
  • Bergemann, Dirk; Bonatti, Alessandro (Wiley Blackwell, 2011-09)
    We develop a model with many advertisers (products) and many advertising markets (media). Each advertiser sells to a different segment of consumers, and each medium is targeting a different audience. We characterize the ...
  • Xie, Huangming; Sun, Lei; Lodish, Harvey F. (Informa Healthcare, 2009-10)
    Obesity is a serious health problem worldwide associated with an increased risk of life-threatening diseases such as type 2 diabetes, atherosclerosis, and certain types of cancer. Fundamental for the development of novel ...
  • Rusolahti, Erkki; Bhatia, Sangeeta N. (Rockefeller University Press, 2010-03)
    The various types of cells that comprise the tumor mass all carry molecular markers that are not expressed or are expressed at much lower levels in normal cells. These differentially expressed molecules can be used as ...
  • Ruoslahti, Erkki; Sailor, Michael J.; Bhatia, Sangeeta N. (Rockefeller University Press, 2010-03)
    The various types of cells that comprise the tumor mass all carry molecular markers that are not expressed or are expressed at much lower levels in normal cells. These differentially expressed molecules can be used as ...
  • Alatas, Vivi; Banerjee, Abhijit (American Economic Association, 2012-06)
    This paper reports an experiment in 640 Indonesian villages on three approaches to target the poor: proxy means tests (PMT), where assets are used to predict consumption; community targeting, where villagers rank everyone ...
  • Warden, Melissa R.; Miller, Earl K. (Society for Neuroscience, 2010-11)
    The prefrontal cortex (PFC) is important for flexible, context-dependent behavioral control. It also plays a critical role in short-term memory maintenance. Though many studies have investigated these functions independently, ...
  • Kaelbling, Leslie P.; Lozano-Perez, Tomas; Hsiao, Kaijen (Robotics: Science and Systems Conference, 2010-01)
    This paper presents a decision-theoretic approach to problems that require accurate placement of a robot relative to an object in the world, including grasping and insertion. The decision process is applied to a robot ...
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