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Browsing MIT Open Access Articles by Title

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  • Lu, Yuan-Ming; Ran, Ying; Lee, Patrick A. (American Physical Society, 2011-06)
    Due to strong geometric frustration and quantum fluctuation, the S = 1/2 quantum Heisenberg antiferromagnet on the kagome lattice has long been considered as an ideal platform to realize a spin liquid (SL), a phase exhibiting ...
  • Weight, Alisha K.; Belser, Jessica A.; Tumpey, Terrence M.; Chen, Jianzhu; Klibanov, Alexander M. (Springer-Verlag, 2013-09)
    Purpose: Previously, polymer-attached zanamivir had been found to inhibit influenza A viruses in vitro far better than did small-molecule zanamivir (1) itself. The aim of this study was to identify in vitro—using the ...
  • Lander, Eric S.; Andersson, Leif; Hjalm, Goran; Andersson, Goran; Lindblad-Toh, Kerstin; Wadelius, Claes; Kullander, Klas; Zierath, Juleen R.; Ponten, Fredrik; De, Sachinandan; Stromberg, Sara; Yan, Jie; Barres, Romain; Lindroth, Anders M.; Gnirke, Andreas; Saenz-Vash, Veronica; Wang, Li; Zhang, Xiaolan; Larhammar, Martin; Wallerman, Ola; Mikkelsen, Tarjei S.; Jaffe, Jacob D.; Jiang, Lin; Markljung, Ellen; Carr, Steven A. (Public Library of Science, 2009-12)
    A single nucleotide substitution in intron 3 of IGF2 in pigs abrogates a binding site for a repressor and leads to a 3-fold upregulation of IGF2 in skeletal muscle. The mutation has major effects on muscle growth, size ...
  • Amsterdam, Adam; Lai, Kevin; Komisarczuk, Anna Z.; Becker, Thomas S.; Bronson, Roderick T.; Hopkins, Nancy H.; Lees, Jacqueline (American Association for Cancer Research, 2009-06)
    We screened an existing collection of zebrafish insertional mutants for cancer susceptibility by histologic examination of heterozygotes at 2 years of age. As most mutants had no altered cancer predisposition, this provided ...
  • Blaker-Lee, Alicia; Gupta, Sunny; McCammon, Jasmine M.; De Rienzo, Gianluca; Sive, Hazel L. (Company of Biologists, The, 2012-05)
    Deletion or duplication of one copy of the human 16p11.2 interval is tightly associated with impaired brain function, including autism spectrum disorders (ASDs), intellectual disability disorder (IDD) and other phenotypes, ...
  • Wardle, Fiona C; Odom, Duncan T; Bell, George W.; Wiellette, Elizabeth L; Herbolsheimer, Elizabeth; Smith, James C; Yuan, Bingbing B.; Sive, Hazel L.; Danford, Timothy William; Young, Richard A. (BioMed Central Ltd, 2006-08)
    We have designed a zebrafish genomic microarray to identify DNA-protein interactions in the proximal promoter regions of over 11,000 zebrafish genes. Using these microarrays, together with chromatin immunoprecipitation ...
  • Nissen, Robert M.; Amsterdam, Adam; Hopkins, Nancy H. (BioMed Central Ltd, 2006-06)
    Background: Craniofacial birth defects result from defects in cranial neural crest (NC) patterning and morphogenesis. The vertebrate craniofacial skeleton is derived from cranial NC cells and the patterning of these cells ...
  • Connolly, Colin B.; Au, Yat Shan; Chae, Eunmi; Tscherbul, Timur V.; Buchachenko, Alexei A.; Ketterle, Wolfgang; Doyle, John M. (American Physical Society, 2013-07)
    We investigate Zeeman relaxation in cold Sb([superscript 4]S[subscript 3/2]∘)–He collisions in a magnetic field. Ensembles of >10[superscript 13] laser-ablated Sb atoms are cooled in cryogenic [superscript 4]He buffer gas ...
  • Johnson, Cort; Newman, Bonna Kay; Brahms, Nathan; Doyle, John M.; Greytak, Thomas J.; Kleppner, Daniel (American Physical Society, 2010-06)
    We have measured the ratio γ of the diffusion cross section to the angular momentum reorientation cross section in the colliding Fe-3He and Ni-3He systems. Nickel (Ni) and iron (Fe) atoms are introduced via laser ablation ...
  • Dong, Hui Yuan; Wang, Jin; Fung, Kin Hung; Fang, Nicholas Xuanlai (American Physical Society (APS), 2011-12)
    We show that, under the presence of a static magnetic field, the photon eigenfrequencies of a circular gyromagnetic cylinder experience a splitting that is proportional to the angular momentum density of light at the ...
  • Potter, Andrew Cole; Lee, Patrick A.; Liu, Jie; Law, K. T. (American Physical Society, 2012-12)
    One of the simplest proposed experimental probes of a Majorana bound state is a quantized (2e[superscript 2]/h) value of zero-bias tunneling conductance. When temperature is somewhat larger than the intrinsic width of the ...
  • Lee, Hae-Seung; Brooks, Lane; Sodini, Charles G. (Institute of Electrical and Electronics Engineers (IEEE), 2009-11)
    Since the first demonstration of a comparator-based switched-capacitor circuit, analog-to-digital (A/D) converters based on virtual ground detection have made steady and significant progress. Comparators have been replaced ...
  • Lajevardi, Payam; Chandrakasan, Anantha P.; Lee, Hae-Seung (Institute of Electrical and Electronics Engineers (IEEE), 2010-11)
    A reconfigurable analog system is presented that implements pipelined ADCs, switched-capacitor filters, and programmable gain amplifiers. Each block employs a zero-crossing based circuit for easy reconfigurability and power ...
  • Oskooi, Ardavan F.; Joannopoulos, John D.; Johnson, Steven G. (Optical Society of America, 2009-06)
    We demonstrate that a holey photonic-crystal fiber with chalcogenide-glass index contrast can be designed to have a complete gap at a propagation constant β=0 that also extends into the non-zero β region. This type of ...
  • Saenz-Otero, Alvar; Katz, Jacob G; Mohan, Swati; Miller, David W.; Chamitoff, Gregory E (Institute of Electrical and Electronics Engineers, 2010-03)
    The designation of the International Space Station as a National Laboratory enhances the ability to use the facility for educational objectives. The MIT Space Systems Laboratory and Aurora Flight Sciences started ...
  • Solomon, Kevin; Prather, Kristala L. Jones (John Wiley & Sons, Inc., 2011-09)
    With increasing price volatility and growing awareness of the lack of sustainability of traditional chemical synthesis, microbial chemical production has been tapped as a promising renewable alternative for the generation ...
  • Schedler, Travis; Etingof, Pavel I. (Walter de Gruyter, 2012-06)
    Let X ⊂ ℂ[superscript 3] be a surface with an isolated singularity at the origin, given by the equation Q(x, y, z) = 0, where Q is a weighted-homogeneous polynomial. In particular, this includes the Kleinian surfaces X =  ...
  • Highcock, E. G.; Schekochihin, A. A.; Cowley, S. C.; Barnes, Michael; Parra Diaz, Felix Ignacio; Roach, C. M.; Dorland, W. (American Physical Society, 2012-12)
    Sheared toroidal flows can cause bifurcations to zero-turbulent-transport states in tokamak plasmas. The maximum temperature gradients that can be reached are limited by subcritical turbulence driven by the parallel velocity ...
  • Chudnovsky, Yakov; Kim, Dohoon; Zheng, Siyuan; Whyte, Warren A.; Bansal, Mukesh; Bray, Mark-Anthony; Gopal, Shuba; Theisen, Matthew A.; Bilodeau, Steve; Thiru, Prathapan; Muffat, Julien; Yilmaz, Omer; Mitalipova, Maya; Woolard, Kevin; Lee, Jeongwu; Nishimura, Riko; Sakata, Nobuo; Fine, Howard A.; Carpenter, Anne E.; Silver, Serena J.; Verhaak, Roel G.W.; Califano, Andrea; Young, Richard A.; Ligon, Keith L.; Mellinghoff, Ingo K.; Root, David E.; Sabatini, David M.; Hahn, William C.; Chheda, Milan G.; Whyte, Warren A. (Elsevier B.V., 2014-01)
    Glioblastoma (GBM) harbors subpopulations of therapy-resistant tumor-initiating cells (TICs) that are self-renewing and multipotent. To understand the regulation of the TIC state, we performed an image-based screen for ...
  • Zhang, Lingbo; Prak, Lina; Rayon-Estrada, Violeta; Thiru, Prathapan; Flygare, Johan; Lim, Bing; Lodish, Harvey F. (Nature Publishing Group, 2013-06)
    Stem cells and progenitors in many lineages undergo self-renewing divisions, but the extracellular and intracellular proteins that regulate this process are largely unknown. Glucocorticoids stimulate red blood cell formation ...
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