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Now showing items 32441-32450 of 34224
Bridging the gap between protein-tyrosine phosphorylation networks, metabolism and physiology in liver-specific PTP1b deletion mice
(Massachusetts Institute of Technology, 2012)
Metabolic syndrome describes a complex set of obesity-related disorders that enhance diabetes, cardiovascular, and mortality risk. Studies of liver-specific protein-tyrosine phosphatase lb (PTPlb) deletion mice (L-PTPlb-/-) ...
The impact of pathological ventilation on aerosol deposition : imaging, insight and intervention
(Massachusetts Institute of Technology, 2015)
Aerosol therapies are often used to treat lung diseases in which ventilation is distributed heterogeneously throughout the lung. As therapeutic aerosols are transported by the inhaled air, it is likely that deposition is ...
Modeling and controlling topographical nonuniformity in thermoplastic micro- and nano-embossing
(Massachusetts Institute of Technology, 2009)
The embossing of thermoplastic polymeric plates is valuable for manufacturing micro- and nanofluidic devices and diffractive optics. Meanwhile, the imprinting of sub-micrometer-thickness thermoplastic layers has emerged ...
Price of anarchy in a Bertrand oligopoly market
(Massachusetts Institute of Technology, 2006)
The price of anarchy quantifies the inefficiency that occurs in the total system objective in the user optimization as compared to the system optimization setting. It is well known that this inefficiency occurs due to lack ...
Invariant mechanical properties of calcium-silicate-hydrates (C-H-S) in cement-based materials : instrumented nanoindentation and microporomechanical modeling
(Massachusetts Institute of Technology, 2006)
Random porous solids such as bone and geomaterials exhibit a multiphase composite nature, characterized by water-filled pores of nm- to m-scale diameter. The natural synthesis and operating environments of such materials ...
Enhancing the customer service experience in call centers using preemptive solutions and queuing theory
(Massachusetts Institute of Technology, 2017)
The security alarms services market in the United States delivers hardware equipment and services to homeowners and businesses to help monitor and enhance personal property protection. Customer satisfaction via wait time ...
Design and analysis of penetrator probes for planetary science applications
(Massachusetts Institute of Technology, 2017)
Penetrator probes emplace by impact into a solid medium, carrying scientific instrumentation to fulfil specified post-impact mission objectives. They have been used successfully for multiple terrestrial applications, but ...
Development and assessment of a soot emissions model for aircraft gas turbine engines
(Massachusetts Institute of Technology, 2008)
Assessing candidate policies designed to address the impact of aviation on the environment requires a simplified method to estimate pollutant emissions for current and future aircraft gas turbine engines under different ...
Hydrologic data assimilation of multi-resolution microwave radiometer and radar measurements using ensemble smoothing
(Massachusetts Institute of Technology, 2006)
Previously, the ensemble Kalman filter (EnKF) has been used to estimate soil moisture and related fluxes by merging noisy low frequency microwave observations with forecasts from a conventional though uncertain land surface ...
Entry, descent and landing vehicle design space exploration for crewed Mars missions
(Massachusetts Institute of Technology, 2008)
With the announcement of the Vision for Space Exploration in 2004, NASA has been preparing plans for a crewed mission to Mars in the next few decades. One challenge associated with crewed missions to the Martian surface ...