Browsing Theses - Dept. of Biology by Title
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Browsing Theses - Dept. of Biology by Title
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(Massachusetts Institute of Technology, 1930)
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2010)A33 is a cell surface glycoprotein of colon epithelium with a long clinical history as a target in antibody-based cancer therapy. Despite being present in normal colon, radio-labeled antibodies against A33 are selectively ...
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(Massachusetts Institute of Technology, 1994)
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A T cell receptor transgenic approach to the study of thymocyte development and autoimmune disease (Massachusetts Institute of Technology, 1999)
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(Massachusetts Institute of Technology, 1995)
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(Massachusetts Institute of Technology, 2010)Tumor development is a multi-step process driven by the collective action of gain-of-function mutations in oncogenes and loss-of-function alterations in tumor suppressor genes. The particular spectrum of mutations in a ...
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(Massachusetts Institute of Technology, 2008)PDZK1 is a four PDZ-domain containing cytoplasmic adaptor protein that binds the Cterminus of the high-density lipoprotein (HDL) receptor SR-BI. Abolishing PDZK1 expression in PDZK1 knockout (KO) mice leads to a ...
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 1997)
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(Massachusetts Institute of Technology, 2000)
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2006)While a fundamental feature of human melanoma is its tendency to metastasize to numerous organs throughout the body, very few animal models recapitulate this essential aspect of the disease. In the work described, it is ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 2006)The large complexity of animals is thought to depend upon the regulation of gene expression and not the number of genes in a genome. Gene expression is a highly conserved process in which genes encoded by DNA are transcribed ...
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(Massachusetts Institute of Technology, 2011)The general amino acid permease Gap1p of Saccharomyces cerevisiae scavenges amino acids from the extracellular medium for use as nitrogen sources in starvation conditions. Because unlimited uptake of both naturally occurring ...
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(Massachusetts Institute of Technology, 2008)Protein degradation is a central mechanism in the regulation of gene expression and activity. Proteolysis regulates not only homeostatic activities, but also the cell's responses to stress. A recurring question underlying ...
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(Massachusetts Institute of Technology, 1994)
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