Browsing Theses - Harvard-MIT Division of Health Sciences and Technology by Title
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Browsing Theses - Harvard-MIT Division of Health Sciences and Technology by Title
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(Massachusetts Institute of Technology, 2006)The United States population is aging, and the need for novel approaches to treat and manage disease continues to grow. Among the diseases that will impact this population, cancer remains a therapeutic area with significant ...
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(Massachusetts Institute of Technology, 2006)In 1992, Accelerated Approval, or Subpart H approval, was added to the NDA regulations so promising products that provide a meaningful therapeutic benefit for serious or life-threatening diseases could be introduced to the ...
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Accelerated image reconstruction for a cylindrical positron tomograph using Fourier domain methods (Massachusetts Institute of Technology, 1990)
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(Massachusetts Institute of Technology, 2005)This study focuses on the acoustic patterns of stop consonants and adjacent vowels as they develop in young children (ages 2;6-3;3) over a six month period. Speech is generated using a series of articulatory, laryngeal, ...
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(Massachusetts Institute of Technology, 2000)
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(Massachusetts Institute of Technology, 2009)In recent years, research in human speech communication suggested that the inventory of sound units that are observed in vowels across languages is strongly influenced by the acoustic properties of the human subglottal ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2006)Acoustic parameters that differentiate between primary stress and non-primary full vowels were determined using two-syllable real and novel words and specially constructed novel words with identical syllable compositions. ...
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(Massachusetts Institute of Technology, 1993)
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(Massachusetts Institute of Technology, 1989)
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(Massachusetts Institute of Technology, 2006)Introduction: In the medical device space, a large proportion of the breakthrough inventions are developed by small firms that use private equity to bring their technologies from concept to varying stages of development. ...
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 2004)Non-muscle cell shape change and motility depend primarily on the dynamics and distributions of cytoplasmic actin. In cells, actin cycles between monomeric and polymeric phases tightly regulated by actin binding proteins ...
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(Massachusetts Institute of Technology, 2009)Adipose tissue serves two main functions in the body: (1) it is the body's primary energy depot; and (2) it also serves as an important endocrine organ, producing and secreting various enzymes, growth factors, cytokines, ...
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(Massachusetts Institute of Technology, 2009)It is widely believed that healthcare information technology (health IT) can improve care and lower costs. However, the pattern and uptake of beneficial features of health IT is poorly understood, and is an important part ...
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(Massachusetts Institute of Technology, 2008)The practice of brachytherapy and brachytherapy dosimetry was investigated with emphasis on evaluations of dose distributions and shielding considerations for both photon- and neutron-emitting radionuclides. Monte Carlo ...
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(Massachusetts Institute of Technology, 2005)Imaging speed is a crucial consideration for magnetic resonance imaging (MRI). The speed of conventional MRI is limited by hardware performance and physiological safety measures. "Parallel" MRI is a new technique that ...
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(Massachusetts Institute of Technology, 2008)Optical Coherence Tomography (OCT) is a developing medical imaging technology that generates micron resolution cross-sectional images of subsurface internal tissue structure in situ and in real time, without the need to ...
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(Massachusetts Institute of Technology, 2009)The clinical application of chemotherapy to brain malignancies has been severely limited because many potential therapeutic agents are typically unable to penetrate the blood-brain barrier (BBB). A novel approach to overcome ...
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(Massachusetts Institute of Technology, 2012)Myotonic dystrophy (DM) is the most common form of adult onset muscular dystrophy, affecting more than 1 in 8000 individuals globally. The symptoms of DM are multi-systemic and include myotonia, severe muscle wasting, ...
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