Browsing Brain and Cognitive Sciences - Ph.D. / Sc.D. by Author "Hachigian, Lea June"

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Modulation of Huntington's disease-associated phenotypes by the striatal-enriched transcription factor Foxp2

Hachigian, Lea June (Massachusetts Institute of Technology, 2017)

Huntington's disease (HD), the most common inherited neurodegenerative disorder, is caused by mutations in the huntingtin (HTT) gene, which encodes a poly-glutamine (polyQ) repeat protein. Despite widespread expression of ...