Application of system optimization theory, supply chain principles, and capacity modeling are increasingly valuable tools for use in pharmaceutical manufacturing facilities. The dynamics of the pharmaceutical industry - ...

Retro-biosynthesis is a novel pathway design method that integrates biocatalysis (in particular, functional group specificity and reactivity of enzymes) and organic chemistry. Using this method, several novel pathways have ...

Recombinant proteins produced by different host organisms have been broadly used as therapeutics. Considering the demand for large quantities of protein drugs, methods are needed to increase reactor titers in a timely and ...

The objective of this thesis is to evaluate a new carbon dioxide compression technology - shock compression - applied specifically to capture-enabled power plants. Global warming has increased public interest in carbon ...

(cont.) produced normal growth curves in the presence of particles. However, the particles do still exhibit some toxicity towards the cells, as the maximum cell density of cells cultured with particles does not reach that ...

As part of its responsibility to the National Institutes for Health, the sequencing operation at the Broad Institute strives for cost-effective production. This thesis attempts to reduce variability in the sequencing ...