Browsing Health Sciences and Technology - Ph.D. / Sc.D. by Title
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Browsing Health Sciences and Technology - Ph.D. / Sc.D. by Title
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(Massachusetts Institute of Technology, 2005)Imaging speed is a crucial consideration for magnetic resonance imaging (MRI). The speed of conventional MRI is limited by hardware performance and physiological safety measures. "Parallel" MRI is a new technique that ...
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(Massachusetts Institute of Technology, 2008)Optical Coherence Tomography (OCT) is a developing medical imaging technology that generates micron resolution cross-sectional images of subsurface internal tissue structure in situ and in real time, without the need to ...
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(Massachusetts Institute of Technology, 2009)The clinical application of chemotherapy to brain malignancies has been severely limited because many potential therapeutic agents are typically unable to penetrate the blood-brain barrier (BBB). A novel approach to overcome ...
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(Massachusetts Institute of Technology, 2014)Studies of human brain function require technologies to non-invasively image neuronal dynamics with high spatiotemporal resolution. The electroencephalogram (EEG) and magnetoencephalogram (MEG) measure neuronal activity ...
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(Massachusetts Institute of Technology, 2012)Myotonic dystrophy (DM) is the most common form of adult onset muscular dystrophy, affecting more than 1 in 8000 individuals globally. The symptoms of DM are multi-systemic and include myotonia, severe muscle wasting, ...
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(Massachusetts Institute of Technology, 2011)Aneuploidy, an abnormal complement of chromosomes, is present in approximately 90% of human malignancies. Despite over 100 years of research, many questions remain regarding the contribution of aneuploidy to the cancer ...
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(Massachusetts Institute of Technology, 2002)Poly-l-lysine and hexadimethrine bromide (polybrene) are cationic polymers which are frequently used to enhance the transduction efficiency of recombinant retroviruses in gene therapy experiments. Conversely, chondroitin ...
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(Massachusetts Institute of Technology, 1993)
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(Massachusetts Institute of Technology, 2008)Regions of phonation exhibiting nonmodal characteristics are likely to contain information about speaker identity, language, dialect, and vocal-fold health. As a basis for testing such dependencies, we develop a representation ...
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(Massachusetts Institute of Technology, 1999)
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(Massachusetts Institute of Technology, 2017)The cochlea is part of the peripheral auditory system that has unique and intriguing features - for example it acts as a wave-based frequency analyzer and amplifies traveling waves. The human cochlea is particularly ...
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(Massachusetts Institute of Technology, 2012)Adhesion-based cell capture on surfaces in microfluidic devices forms the basis of numerous biomedical diagnostics and in vitro assays. Solid surface microfluidic platforms have been widely explored for biomedical diagnostics ...
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(Massachusetts Institute of Technology, 2009)Epilepsy is a chronic disorder of the central nervous system that predisposes individuals to experiencing recurrent seizures. It affects 3 million Americans and 50 million people world-wide. A seizure is a transient ...
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(Massachusetts Institute of Technology, 2016)Clinical predictive models are useful in predicting a patient's risk of developing adverse outcomes and in guiding patient therapy. In this thesis, we explored two different ways to apply domain knowledge to improve clinical ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2011)This thesis builds on previous efforts to develop tactile speech-reception aids for the hearing-impaired. Whereas conventional hearing aids mainly amplify acoustic signals, tactile speech aids convert acoustic information ...
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(Massachusetts Institute of Technology, 2000)
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(Massachusetts Institute of Technology, 2016)Communication in environments with multiple competing sound sources can be challenging, even for listeners with normal hearing thresholds (NHT). This difficulty in "normal" listeners is thought to arise from central sites ...
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(Massachusetts Institute of Technology, 2012)Accurate sensory perception in noisy environments requires physiological mechanisms that reduce sensory interference. In the auditory system, it has been hypothesized that attentional control of cochlear responses to sound ...
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(Massachusetts Institute of Technology, 2015)RNA-sequencing is a sensitive method for inferring gene expression and provides additional information regarding splice variants, polymorphisms and novel genes and isoforms. Using this extra information greatly increases ...
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