Browsing Health Sciences and Technology - Ph.D. / Sc.D. by Title
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Browsing Health Sciences and Technology - Ph.D. / Sc.D. by Title
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(Massachusetts Institute of Technology, 2006)The prevalence of severe to profound bilateral congenital hearing loss is estimated at 1 in 1000 births, at least half of which can be attributed to a genetic cause. To date, mutations in at least 67 genes have been ...
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(Massachusetts Institute of Technology, 2009)Disrupted blood-brain barrier after an ischemic attack can cause vasogenic edema and increase the risk of hemorrhagic transformation. Therefore, early detection and monitoring of BBB damage is important in the pathological ...
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(Massachusetts Institute of Technology, 1997)
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(Massachusetts Institute of Technology, 2011)This thesis is motivated by the gaps between speech science and technology in analyzing dialects. In speech science, investigating phonetic rules is usually manually laborious and time consuming, limiting the amount of ...
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(Massachusetts Institute of Technology, 2008)Otitis media (OM) is the most common specifically-treated childhood disease in the United States. The widespread use of systemic antibiotics against a disease of such high incidence is believed to be a driving force behind ...
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(Massachusetts Institute of Technology, 1992)
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(Massachusetts Institute of Technology, 2012)Unlike lower vertebrates, capable of spontaneous hair cell regeneration, mammals experience permanent sensorineural hearing loss following hair cell damage. Although low levels of hair cell regeneration have been demonstrated ...
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(Massachusetts Institute of Technology, 2008)Parallel MRI techniques allow acceleration of MR imaging beyond traditional speed limits. In parallel MRI, radiofrequency (RF) detector coil arrays are used to perform some degree of spatial encoding which complements ...
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(Massachusetts Institute of Technology, 2011)Recovery from central nervous system (CNS) injuries is hindered by a lack of spontaneous regeneration. In injuries such as stroke and traumatic brain injury, loss of viable tissue can lead to cavitation as necrotic debris ...
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(Massachusetts Institute of Technology, 2011)Basic scientific research over the past few decades has shown some light on the complex pathophysiology of SCI and has enhanced our understanding of some of the important factors that contribute to the lack of regeneration ...
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(Massachusetts Institute of Technology, 2008)Bacterial infections represent a significant source of morbidity and mortality. Biofilms and antibiotic resistance pose challenges to our future ability to treat bacterial diseases with antibiotics (1). Bacteria frequently ...
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Combined-channel instantaneous frequency analysis for audio source separation based on comodulation (Massachusetts Institute of Technology, 2008)Normal human listeners have a remarkable ability to focus on a single sound or speaker of interest and to block out competing sound sources. Individuals with hearing impairments, on the other hand, often experience great ...
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(Massachusetts Institute of Technology, 2009)The use of functional magnetic resonance imaging (fMRI) to study the non-human primate brain has been developed over the past decade. Primate fMRI has many attractive features: it allows validation of previous homology ...
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(Massachusetts Institute of Technology, 2007)The ear represents a remarkable achievement in sensory physiology. It is very fast (timescales on the order of 1-100 kHz), has a large bandwidth (-10 octaves in the human), highly sensitive (threshold is ultimately determined ...
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(Massachusetts Institute of Technology, 1993)
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(Massachusetts Institute of Technology, 2001)Deep vein thrombosis (DVT) of the lower extremity and induced pulmonary embolism are common complications resulting from prolonged periods of bed-rest or immobilization of the limbs. One of the most effective methods of ...
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(Massachusetts Institute of Technology, 2012)Vertebrate hair cells respond to mechanical stimuli with an inward current that is carried by extracellular cations through mechanically-gated transmembrane ion channels called transduction channels, located in the hair ...
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(Massachusetts Institute of Technology, 2007)High-throughput molecular data are revolutionizing biology by providing massive amounts of information about gene expression and regulation. Such information is applicable both to furthering our understanding of fundamental ...
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(Massachusetts Institute of Technology, 2009)Large volumes of continuous waveform data are now collected in hospitals. These datasets provide an opportunity to advance medical care, by capturing rare or subtle phenomena associated with specific medical conditions, ...
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(Massachusetts Institute of Technology, 2007)Drug-eluting stents (DES) virtually eradicate the clinical phenomena of vessel restenosis; yet, they also increase the short and long term risks for stent thrombosis. To improve their safety and efficacy, it is critical ...
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