Browsing Health Sciences and Technology - Master's degree by Title
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Browsing Health Sciences and Technology - Master's degree by Title
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(Massachusetts Institute of Technology, 2006)The United States population is aging, and the need for novel approaches to treat and manage disease continues to grow. Among the diseases that will impact this population, cancer remains a therapeutic area with significant ...
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(Massachusetts Institute of Technology, 2006)In 1992, Accelerated Approval, or Subpart H approval, was added to the NDA regulations so promising products that provide a meaningful therapeutic benefit for serious or life-threatening diseases could be introduced to the ...
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(Massachusetts Institute of Technology, 2006)Introduction: In the medical device space, a large proportion of the breakthrough inventions are developed by small firms that use private equity to bring their technologies from concept to varying stages of development. ...
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(Massachusetts Institute of Technology, 2009)It is widely believed that healthcare information technology (health IT) can improve care and lower costs. However, the pattern and uptake of beneficial features of health IT is poorly understood, and is an important part ...
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(Massachusetts Institute of Technology, 2010)Medicare coverage policies of medical procedures can be promulgated at a national level by the Centers of Medicare and Medicaid Services (CMS) as National Coverage Determinations (NCDs) or at a local level by Medicare ...
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Applying axiomatic design methodology to enable adaptation of clinical guidelines to local contexts (Massachusetts Institute of Technology, 2004)Background: Local adaptation of guidelines may increase compliance with guidelines that have been developed at a national level and are often not used in practice because of contextual factors. We have developed a ...
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(Massachusetts Institute of Technology, 2007)The pipeline productivity challenge facing large, publicly traded pharmaceutical companies, collectively referred to as "Big Pharma," is well known. The unprecedented success Big Pharma achieved over the past few decades ...
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(Massachusetts Institute of Technology, 2007)The goal of this study is to explore the economic conditions that favor the joint development of therapeutics and companion diagnostics. I hypothesize that predictive biomarkers can generate economic value in drug development ...
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(Massachusetts Institute of Technology, 2011)This thesis investigates the commercial viability of developing and commercializing targeted oncology drugs directed at a specific tumor mutation instead of all forms and mutations of a single target. While oncologic drugs ...
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(Massachusetts Institute of Technology, 2012)Hepatitis C (HCV) is the most common bloodborne infection in the United States. Although the incidence of HCV is declining, the burden of the disease is rising, driven by the increasing rates of end-stage liver disease and ...
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(Massachusetts Institute of Technology, 2005)In normal-hearing ears, sound waves are amplified within the cochlea and a small fraction of the sound energy travels backward out into the ear canal, producing sounds known as "otoacoustic emissions" (OAE) that can be ...
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(Massachusetts Institute of Technology, 2010)Autism spectrum disorder (ASD) is characterized by many behavioral symptoms, including delays in social and communicative development. A cluster of symptoms concentrate on speech and language development, especially ...
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(Massachusetts Institute of Technology, 2011)The purpose of the research was to identify the clinical and commercial benefits of switching from intravenous (IV) to buccal delivery of antibiotics. then, the research continued to select 3-5 antibiotics that best met ...
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(Massachusetts Institute of Technology, 2007)Recently, hospitals, regulatory agencies, and insurers have renewed their focus on improving patient care and safety. Outcomes based measures are being utilized and hospitals are being asked to report on whether patients ...
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(Massachusetts Institute of Technology, 2010)The history of private philanthropy in the US has been dominated by family foundations with arms-length philanthropy practices that largely existed in separation from commercial enterprise and business operations. This ...
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(Massachusetts Institute of Technology, 2010)Background: The commoditization of high-throughput gene expression sequencing and microarrays has led to a proliferation in both the amount of genomic and clinical data that is available. Descriptive textual information ...
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(Massachusetts Institute of Technology, 2009)It has become increasingly important for companies in the biopharmaceutical industry to maximize the clinical, commercial and economic impact of their products on a global scale. In this context, both Western and Asian ...
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(Massachusetts Institute of Technology, 2011)Innovation within the medical device industry had led to tremendous advances in the provision of care for patients worldwide. Continued progress in the treatment of disease will require effective processes for managing and ...
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(Massachusetts Institute of Technology, 2005)Breath analysis has potential to become a new medical diagnostic modality. In this thesis, a method for the analysis of human expired breath was developed using gas chromatography-mass spectroscopy. It was subsequently ...
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(Massachusetts Institute of Technology, 2006)Since the Bayh-Dole Act of 1980, the commercialization of ideas generated in academia has driven significant startup activity and expansion in the life sciences. This commercial transformation has been shown by others to ...
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