Browsing Department of Biology by Title
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Browsing Department of Biology by Title
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(Massachusetts Institute of Technology, 1997)
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 2013)Sexual reproduction depends on meiosis, the specialized cell division that gives rise to gametes. During meiosis, two consecutive rounds of chromosome segregation follow one round of DNA replication to yield four haploid ...
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(Massachusetts Institute of Technology, 2004)This suggests that the S phase cyclin, which first activates DNA replication, then acts locally at the origin to prevent pre-RC formation.
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(Massachusetts Institute of Technology, 2012)The objective of this work is to obtain an in depth understanding of how embryonic stem cell-secreted signals contribute to their identity. We analyze the contribution of broad and specific signals present in the cell-secreted ...
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(Massachusetts Institute of Technology, 2012)Regeneration of missing body parts is biologically fascinating, yet poorly understood. Many instances of regeneration, such as the replacement of amphibian limbs or planarian heads, require both a source for new cellular ...
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(Massachusetts Institute of Technology, 2014)The poly(ADP-ribose) polymerase (PARP) protein family consists of seventeen enzymes and generates ADP-ribose (ADPr) posttranslational modifications onto target proteins using NAD* as a substrate. While functions for PARPs ...
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(Massachusetts Institute of Technology, 2013)Integrative and conjugative elements (ICEs) are mobile genetic elements that are normally found stably integrated into bacterial chromosomes, but under certain situations can excise and transfer to a recipient cell through ...
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(Massachusetts Institute of Technology, 1995)
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(Massachusetts Institute of Technology, 2006)Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation ...
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(Massachusetts Institute of Technology, 1994)
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(Massachusetts Institute of Technology, 2004)Bacteria keep track of their population density by using extracellular signaling molecules. In response to the accumulation of these signals, changes in gene expression coordinate the switch from unicellular activity to ...
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(Massachusetts Institute of Technology, 1987)
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(Massachusetts Institute of Technology, 1997)
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(Massachusetts Institute of Technology, 2011)Cataract, the leading cause of blindness worldwide, is the opacification of the eye lens. In.age-related cataract, as well as roughly one half of congenital cataract cases, aggregation or precipitation of crystallin proteins ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 1999)
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(Massachusetts Institute of Technology, 1994)
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(Massachusetts Institute of Technology, 2001)
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(Massachusetts Institute of Technology, 2007)Conserved signal transduction pathways coordinate all aspects of metazoan development, including cell fate specification, differentiation, and growth. Rather than functioning as completely independent modules, signaling ...
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