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Browsing Department of Biology by Title
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(Massachusetts Institute of Technology, 1975)
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(Massachusetts Institute of Technology, 2010)In metastatic cancer, cells must be able to migrate from their original environment, move through the blood or lymphatic system, and colonize a distant organ. Mena, a member of the Ena/VASP family of proteins, is upregulated ...
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(Massachusetts Institute of Technology, 2013)The Mitogen-activated protein kinase(MAPK) signaling pathway has been studied intensively in the context of neoplastic transformation. Other studies have focused on the roles of this pathway during development and have ...
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 2005)The geographic distribution and dynamics of coastal benthic populations are shaped by physical - biological interactions affecting larval dispersal and the demography of juvenile and adult individuals. This thesis focused ...
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(Massachusetts Institute of Technology, 2013)The sinking flux of particles is an important removal mechanism of carbon from the surface ocean as part of the biological pump and can play a role in cycling of other chemical species. This work dealt with improving methods ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2013)Mammalian target of rapamycin complex I (mTORC1) is an atypical Ser/Thr kinase that regulates cellular and organismal growth. Accordingly, mTORC1 has substantial roles in regulating insulin sensitivity and lifespan, and ...
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(Massachusetts Institute of Technology, 2007)The high capacity general amino acid permease in Saccharomyces cerevisiae (GAP1) is regulated such that it actively imports amino acids into the cell from the extracellular medium only when internal amino acid levels are ...
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(Massachusetts Institute of Technology, 1938)A considerable amount of work has been done on the growth of A. aerogenes and E. coli in synthetic media, but little work has been undertaken on the utilization by these organisms of amino acids as comparative sources of ...
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Analyses of the roles of the UmuDC proteins of E. coli in SOS mutagenesis and cell cycle regulation (Massachusetts Institute of Technology, 1997)
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(Massachusetts Institute of Technology, 1988)
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(Massachusetts Institute of Technology, 2006)Numerous DNA double-strand breaks (DSBs) are introduced into the genome in the course of meiotic recombination. This poses a significant hazard to the genomic integrity of the cell. Studies in a number of organisms have ...
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(Massachusetts Institute of Technology, 1999)
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(Massachusetts Institute of Technology, 1999)
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(Massachusetts Institute of Technology, 2011)Gene amplification in Drosophila follicle cells is an excellent model to study origin specification and developmental regulation of DNA replication in vivo. We mapped all follicle cell amplicons using a comparative genomic ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2003)The Neurofibromatosis type 2 tumor suppressor gene (NF2) is mutated in inherited and sporadically occurring central nervous system tumors. The NF2 encoded protein, merlin, shares close sequence similarity in its amino-terminal ...
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