Browsing Biological Engineering - Ph.D. / Sc.D. by Title
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Browsing Biological Engineering - Ph.D. / Sc.D. by Title
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(Massachusetts Institute of Technology, 2007)A grand challenge of systems biology is to model the cell. The cell is an integrated network of cellular functions. Each cellular function, such as immune response, cell division, metabolism or apoptosis, is defined by an ...
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(Massachusetts Institute of Technology, 2008)Many cellular processes are governed by large and highly-complex networks of chemical interactions and are therefore difficult to intuit. Computational modeling provides a means of encapsulating information about these ...
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 2009)The inability of articular cartilage to heal after damage or disease has motivated investigation of novel cartilage tissue engineering technologies. The objective of this thesis was to advance the use of self-assembling ...
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(Massachusetts Institute of Technology, 2006)Molecular markers for adult stem cells (ASCs) are highly demanded for research and clinical applications. The development of specific molecular markers for ASCs has been difficult mainly due to the technical barriers in ...
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(Massachusetts Institute of Technology, 2001)Glycosaminoglycans are complex polysaccharides that exist at the cell/extracellular matrix interface. As such, these information-dense molecules are key regulators of extracellular signals. However, to date, there has been ...
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(Massachusetts Institute of Technology, 2006)Recent studies have developed preliminary wiring diagrams for a number of important biological networks. However, the design principles governing the construction and operation of these networks remain mostly unknown. To ...
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(Massachusetts Institute of Technology, 2007)Our understanding of why biological systems are designed in a particular way would benefit from biophysically-realistic models that can make accurate predictions on the time-evolution of molecular events given arbitrary ...
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(Massachusetts Institute of Technology, 2012)Normalizing angiogenesis is a promising strategy for treatments of cancer and several disorders plagued by misregulated blood supplies. To address the daunting complexity of angiogenesis arising from multiple phenotypic ...
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(Massachusetts Institute of Technology, 2012)The adaptive immune system is an extraordinarily diverse inventory comprised of highly specialized cells, the differentiation of which requires numerous lineage specifications at various developmental stages. The precise ...
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(Massachusetts Institute of Technology, 2008)Nanoparticle-protein conjugates have a variety of applications in imaging, sensing, assembly and control. The nanoparticle-protein interface is made of numerous complex interactions between protein side-chains and the ...
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(Massachusetts Institute of Technology, 2007)Molecular springs have recently emerged as the basis for the fastest and most powerful movements at the cellular level in biology. The spasmoneme of the protozoan, Vorticella convallaria, is a model molecular spring, relying ...
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(Massachusetts Institute of Technology, 2012)Proteins and polysaccharides are of growing importance as a source for novel therapeutic compounds and target a range of diseases, from cancer to infections from pathogens. However, owing to their large and complex structures, ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2008)Parkinson's disease (PD) is a primarily motor disorder which affects at least half a million people in the US alone. Deep brain stimulation (DBS) is a neurosurgical intervention by which neural structures are stimulated ...
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(Massachusetts Institute of Technology, 2006)Live or attenuated pathogens are the basis of many successful vaccines due in part to the orchestrated response of dendritic cells (DCs) triggered by these immunizations, which includes (1) DC and DC precursor attraction ...
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(Massachusetts Institute of Technology, 2007)Cholesterol gallstones are exceptionally common and cost nearly 10 billion U.S. dollars annually. Despite a half-century of basic and clinical research questions still remain about cholesterol gallstone pathogenesis. The ...
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(Massachusetts Institute of Technology, 2006)Glycans are chemically heterogeneous macromolecules that have profound importance in a variety of biological processes. Located at the surfaces of cells, deposited in the extracellular matrix, or attached to soluble signaling ...
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(Massachusetts Institute of Technology, 2012)With constantly increasing demand for lightweight power sources, electrode architectures that eliminate the need for conductive and organic additives will increase mass specific energy and power densities. The increased ...
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