Browsing Department of Brain and Cognitive Sciences by Title
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Browsing Department of Brain and Cognitive Sciences by Title
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(Massachusetts Institute of Technology, 2004)It has been assumed that Ca2+ influx of different duration and amplitude would generate different level of potentiation. The conventional protocols of generating LTP have been 1. tetanic stimulation of presynaptic cell, ...
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(Massachusetts Institute of Technology, 2001)Long term potentiation (LTP) of synaptic transmission at the CA3-CA1 hippocampal synapse is a model synaptic plasticity mechanism that may underlie hippocampal dependent learning and memory. Inhibition of post-synaptic ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2002)The ability to group stimuli into meaningful categories is a fundamental cognitive process though little is known its neuronal basis. To address this issue, we trained monkeys to perform a categorization task in which they ...
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(Massachusetts Institute of Technology, 2006)Despite decades of evidence for functional plasticity in the adult brain, the role of structural plasticity in its manifestation remains unclear. cpg15 is an activity-regulated gene encoding a membrane-bound ligand that ...
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(Massachusetts Institute of Technology, 1995)
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(Massachusetts Institute of Technology, 2010)The basal ganglia, and specifically the sensorimotor (dorsolateral) striatum, have been implicated in stimulus-response learning. Here, I analyze the role the striatum plays in learning. We recorded from neurons of the ...
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(Massachusetts Institute of Technology, 2006)Regulation of gene transcription by neuronal activity is thought to be key to the translation of sensory experience into long-term changes in synaptic structure and function. Here we show that cgp15, a gene encoding an ...
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(Massachusetts Institute of Technology, 1995)
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(Massachusetts Institute of Technology, 2011)This dissertation documents how healthy aging and Parkinson's disease (PD) affect brain anatomy and physiology and how these neural changes relate to measures of cognition and perception. While healthy aging and PD are ...
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(Massachusetts Institute of Technology, 2004)(cont.) increased activity whenever recollection was attempted, independent of the level of recollection success. The results are consistent with the hypothesis that increased left-lateralized retrieval activity in older ...
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(Massachusetts Institute of Technology, 1997)
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(Massachusetts Institute of Technology, 2005)(cont.) baseline, and that some coherence-based approaches best predict the human data. However, coherence-based algorithms that operate on trees did not perform as well as coherence-based algorithms that operate on more ...
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(Massachusetts Institute of Technology, 2003)There is broad agreement that the hippocampus is crucially involved in the formation of richly-detailed, long term memories of events in humans. A key aspect of such memories is the temporal order and spatial context of ...
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(Massachusetts Institute of Technology, 2007)Perceptual systems are specialized for transducing and interpreting information from the environment. But perceptual systems can also be used for processing information that arises from other sources, such as mental imagery ...
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(Massachusetts Institute of Technology, 2008)The ability to switch between tasks reflects a fundamental part of our intelligence. A foundation of this ability lies in perceiving and processing information pertinent to the situation at hand. It is our capacity to ...
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(Massachusetts Institute of Technology, 1991)
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 1993)
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(Massachusetts Institute of Technology, 1995)
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