Browsing Biology - Ph.D. / Sc.D. by Title
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Browsing Biology - Ph.D. / Sc.D. by Title
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(Massachusetts Institute of Technology, 2008)E2F transcription factors were originally identified as regulators of cell cycle and cellular proliferation. In vivo mouse models have uncovered novel roles for these proteins in different developmental processes. This ...
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 2008)In this thesis, I provide quantitative descriptions of toothed whale echolocation and foraging behavior, including assessment of the effects of noise on foraging behavior and the potential influence of ocean acoustic ...
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(Massachusetts Institute of Technology, 2014)Microbes occupy a wide range of important niches ranging from global biogeochemical cycles to metabolism in the human gut. Yet microbes rarely act in isolation. Instead, they thrive in complex communities with myriad ...
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(Massachusetts Institute of Technology, 2015)Microbial secondary metabolites are among the most structurally and functionally complex molecules in nature. Lanthipeptides are ribosomally derived peptide secondary metabolites that undergo extensive post-translational ...
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(Massachusetts Institute of Technology, 2004)The marine cyanobacteria Prochlorococcus and Synechococcus are numerically dominant primary producers in the oceans. Each genera consists of multiple physiologically and genetically distinct groups (termed "ecotypes" in ...
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(Massachusetts Institute of Technology, 2006)Marine thecate heterotrophic dinoflagellates likely play an important role in the consumption of primary productivity and in the trophic structure of the plankton, yet we know little about these species. This thesis expanded ...
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(Massachusetts Institute of Technology, 2017)Animal movement is motivated in part by energetic constraints, where fitness is maximized by minimizing energy consumption. The energetic cost of movement depends on the resistive forces acting on an animal; changes in ...
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(Massachusetts Institute of Technology, 2010)In budding yeast, aneuploidy has a detrimental effect in cell growth and proliferation. The work presented here shows that most aneuploid yeast strains delay cell cycle entry by increasing the critical size for budding and ...
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(Massachusetts Institute of Technology, 2010)Activating mutations in RAS oncogenes commonly arise in human cancers. However, in experimental settings, oncogenic RAS has most often been studied at supraphysiological levels of expression. Importantly, work by others ...
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(Massachusetts Institute of Technology, 2004)The Par system contributes to stable inheritance of plasmids and chromosomes in diverse bacterial species. Faithful chromosome partitioning is important to dividing cells because anucleate, or chromosomeless, cells are not ...
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(Massachusetts Institute of Technology, 2006)Caspases play an important role in apoptosis, or programmed cell death. In particular, three highly related effector caspases, caspases-3, -6, and -7, translate upstream death signals into the physical manifestations of ...
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(Massachusetts Institute of Technology, 2004)Nervous system development is a complex morphogenetic process. Cell migration, axon guidance and many other regulated cell shape changes build a functional nervous system. These processes depend upon regulation of the actin ...
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(Massachusetts Institute of Technology, 2005)Nanobiotechnology aims to exploit biomolecular recognition and self-assembly capabilities for integrating advanced materials into medicine and electronics. In particular, peptides have exhibited the ability to specifically ...
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(Massachusetts Institute of Technology, 1995)
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(Massachusetts Institute of Technology, 2014)The human body is made up of a diverse array of cell types, each with specialized properties and functions that support the organism as a whole. Despite this variability, with few exceptions, these cells contain the same ...
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(Massachusetts Institute of Technology, 2017)How cellular and molecular processes are orchestrated to generate complex tissues and anatomical patterns is a longstanding question in biology. Planarians, flatworms capable of remarkable whole-body regeneration, are well ...
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(Massachusetts Institute of Technology, 2013)Co-evolution of pathogen and host helps drive biological diversity. Unlike viral-host interactions, little is known about the co-evolution of eukaryotic pathogens with their hosts. The intracellular parasite Toxoplasma ...
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(Massachusetts Institute of Technology, 1995)
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(Massachusetts Institute of Technology, 2015)Hydrothermal vents and coral ecosystems are conspicuous biological hot spots in the deep-sea. These ecosystems face increasing threats from human activities. Having thorough taxonomic inventories as well as understanding ...
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