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Department of Chemistry

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Department of Chemistry


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Recent Submissions

  • Branon, Tess C (Massachusetts Institute of Technology, 2018)
    Protein interaction networks and protein compartmentalization underlie all signaling and regulatory processes in cells. Traditional approaches to proteomics employ mass spectrometry (MS) coupled to biochemical fractionation ...
  • Lee, Myungwoon (Massachusetts Institute of Technology, 2018)
    Solid-state nuclear magnetic resonance (SSNMR) spectroscopy is an essential tool to elucidate the structure, dynamics, and function of biomolecules. This thesis mainly focuses on the structure determination of the hydrophobic ...
  • Han, Yisu, Ph. D. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2018)
    APEX is an engineered peroxidase that catalyzes the oxidation of a wide range of substrates, facilitating its use in a variety of applications, from subcellular staining for electron microscopy to proximity biotinylation ...
  • Lu, Zeyu (Zeyu Mike) (Massachusetts Institute of Technology, 2018)
    The intracellular delivery of therapeutic biomolecules such as oligonucleotides and proteins remains a key challenge today. Protective antigen, a naturally evolved protein translocase derived from Bacillus anthracis, has ...
  • Rojas, Anthony J. (Anthony Jose) (Massachusetts Institute of Technology, 2018)
    physicochemical properties in comparison to their linear counterparts. Here we detail a method for a divergent macrocyclization of unprotected peptides by crosslinking two cysteine residues with bis-palladium organometallic ...