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Browsing Department of Chemistry by Title
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(Massachusetts Institute of Technology, 1993)
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(Massachusetts Institute of Technology, 2011)Amyloid fibrils are insoluble, non-crystalline protein filaments associated with a number of diseases such as Alzheimer's and Type Il diabetes. They can have a functional role in different organisms and many proteins and ...
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(Massachusetts Institute of Technology, 1958)
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(Massachusetts Institute of Technology, 2004)Highly convergent annulation strategies have been developed for the synthesis of azulenes and polycyclic nitrogen heterocycles. Specifically, substituted azulenes have been synthesized via a ring expansion-annulation ...
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(Massachusetts Institute of Technology, 2013)Viruses are a major cause of human morbidity and mortality in the world. New effective approaches to stop their spread are paramount. Herein, two approaches toward this goal are explored: (i) developing multivalent ...
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(Massachusetts Institute of Technology, 2002)Our research over the last four years has been focused on the development of mild and general methods for conducting palladium-catalyzed carbon-carbon bond forming reactions utilizing the bulky and electron-rich ...
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(Massachusetts Institute of Technology, 1998)
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(Massachusetts Institute of Technology, 1995)
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Application of sensitive spectroscopic techniques to intramolecular dynamics and combustion kinetics (Massachusetts Institute of Technology, 2002)Modifications of Cavity Ringdown Spectroscopy (CRD) for use in the UV region are discussed. These modifications partially overcome the low sensitivity of CRD in the UV (due to lower mirror reflectivity, R - 0.99) by removal ...
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(Massachusetts Institute of Technology, 1995)
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(Massachusetts Institute of Technology, 2002)Based on a strategy developed in our group for the desymmetrization of planar heterocycles, we have designed, synthesized, and resolved a number of bidentate, C2-symmetric planar-chiral bis(azaferrocenes) that bear a ...
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(Massachusetts Institute of Technology, 2010)Magic Angle Spinning (MAS) solid state nuclear magnetic resonance (SSNMR) is a developing method for determining the structures and studying the dynamics and functions of biological molecules. This method is particularly ...
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(Massachusetts Institute of Technology, 1988)
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(Massachusetts Institute of Technology, 2004)Because Lewis acids are very versatile mediators of a variety of stereoselective organic transformations, a great deal of effort has been devoted toward the development of chiral Lewis acids. This thesis describes the ...
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(Massachusetts Institute of Technology, 2002)The development of planar-chiral heterocycles for asymmetric catalysis and their applications to enantioselective processes were investigated. Reactions including the kinetic resolution of propargylic alcohols, the ...
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(Massachusetts Institute of Technology, 2003)In PART I, the design and the synthesis of planar-chiral phosphaferrocene-oxazolines, a new class of P,N-ligands, are described. The modular nature of their structure allows easy access to a number of analogues in ...
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(Massachusetts Institute of Technology, 1995)
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(Massachusetts Institute of Technology, 2005)The information in genomes is only partially contained in the linear sequence of their nucleotides. Their folding into dynamic three-dimensional structures creates spatial relationships between loci that likely play important ...
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(Massachusetts Institute of Technology, 1996)
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