DSpace@MIT: Browsing Department of Chemistry by Title

Investigating exciton correlations using coherent multidimensional optical spectroscopy

Turner, Daniel Burton (Massachusetts Institute of Technology, 2010)

The optical measurements described in this thesis reveal interactions among bound electron-hole pairs known as excitons in a semiconductor nanostructure. Excitons are quasiparticles that can form when light is absorbed by ...

Investigating the pathway of asparagine-linked glycoprotein biosynthesis

O'Reilly, Mary K. (Mary Katherine) (Massachusetts Institute of Technology, 2006)

The biosynthesis of asparagine-linked glycoproteins, highly conserved throughout all eukaryotes, requires a dolichylpyrophosphate-linked tetradecasaccharide precursor (Dol-PP-GlcNAc2Man9Glc3), from which the tetradecasaccharide ...

Investigation of asparagine-linked glycosylation in archaeal and bacterial systems

Larkin, Angelyn (Angelyn Kathryne) (Massachusetts Institute of Technology, 2011)

Asparagine-linked protein glycosylation entails the stepwise assembly of an oligosaccharide onto a polyisoprenyl diphosphate carrier, followed by the en bloc transfer of the glycan onto acceptor proteins by oligosaccharyl ...

Investigation of DNP mechanisms : the solid effect

Smith, Albert Andrew (Massachusetts Institute of Technology, 2012)

Dynamic Nuclear Polarization (DNP) enhances signal to noise in NMR experiments, by transferring the large electron Boltzmann polarization to nuclear polarization, via application of pulsed or continuous-wave microwave ...

Investigation of freezing properties of polar statospheric cloud particles with optical microscopy

Ng, Huey Pin (Massachusetts Institute of Technology, 1997)

Investigation of microbicidal activity of surface-immobilized hydrophobic polycations

Hsu, Bryan Boen (Massachusetts Institute of Technology, 2011)

Hydrophobic polycations have been shown to completely kill bacterial, fungal, and viral pathogens, on-contact. Herein we describe advances with this technology on two fronts: (1) innovation of a polycationic-derivative ...

Investigation of the kinetics of protein folding and the ensemble of conformations in non-native states of proteins by liquid NMR spectroscopy

Wirmer, Julia (Massachusetts Institute of Technology, 2005)

For a complete description of protein folding dynamics and the structure of the folded state, of unfolded and of non-native states of proteins and the kinetics of protein folding from the unfolded state to the folded state ...

Investigation of the mechanism of radical propagation in E. coli ribonucleotide reductase by site-specific incorporation of unnatural amino acids

Seyedsayamdost, Mohammad R (Massachusetts Institute of Technology, 2008)

Inside the cell, ribonucleotide reductases (RNRs) are responsible for the conversion of nucleotides to 2'-deoxynucleotides, an essential step in DNA biosynthesis and repair. The E. coli RNR is the best studied RNR to date ...

Investigation of the yeast oligosaccharyl transferase

Dempski, Robert E. (Robert Edward), 1974- (Massachusetts Institute of Technology, 2003)

Oligosaccharyl transferase catalyzes the first commited step in N-linked glycosylation. The enzyme complex from Saccharomyces cerevisiae includes nine membrane bound proteins located in the lipid bilayer of the endoplasmic ...

Investigation of uranium oxide of low oxidation state

Nelson, Carl W (Massachusetts Institute of Technology, 1957)

Investigation of zinc metalloneurochemistry with fluorescent sensors based on fluorescein platforms

Burdette, Shawn C. (Shawn Christopher), 1975- (Massachusetts Institute of Technology, 2003)

Chapter 1. CoordinationChemistry for the Neurosciences Metal ions are integral components of numerous enzymes and proteins. Although the field of bioinorganic chemistry has not focused on the brain and central nervous ...

Investigations of sterically demanding ligands in molybdenum and tungsten monopyrrolide monoalkoxide catalysts for olefin metathesis

Gerber, Laura Claire Heidkamp (Massachusetts Institute of Technology, 2013)

Chapter 2 investigates the mechanism of the temperature-controlled polymerization of 3- methyl-3-phenylcyclopropene (MPCP) by Mo(NAr)(CHCMe 2Ph)(Pyr)(OTPP) (Ar = 2,6- diisopropylphenyl, Pyr = pyrrolide, OTPP = 2,3,5,6-te ...

Investigations of structure and dynamics in solids by high resolution nuclear magnetic resonance

Rothwell, William Paul (Massachusetts Institute of Technology, 1980)

Investigations of the inhibition mechanisms of human ribonucleotide reductase by gemcitabine-5'-diphosphate and saccharomyces cerevisiae ribonucleotide reductase by Sml1

Wang, Jun, Ph. D. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2009)

Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides supplying the dNTPs required for DNA replication and DNA repair. Class I RNRs require two subunits ([alpha] and [beta]) for activity. ...

In vivo cofactor biosynthesis and maintenance in the class Ia ribonucleotide reductase small subunit of Escherichia coli

Wu, Chia-Hung, Ph. D. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2009)

The small subunit ([beta]2) of Escherichia coli class Ia ribonucleotide reductases (RNRs) contains a diferric tyrosyl radical (Y*) cofactor essential for the conversion of nucleotides to deoxynucleotides that are needed ...

Iron macrocycle complexes

Koch, Stephen Andrew (Massachusetts Institute of Technology, 1975)

The isolation of senescent populations of S. cerevisiae (baker's yeast)

Claus, James J. (James Jon) (Massachusetts Institute of Technology, 1995)

Isotope edited FT-IR of peptides

Anderson, Todd Sterling (Massachusetts Institute of Technology, 1996)

I. Synthesis of mycarose from an acyclic precursor ; II. studies toward the sysnthesis of Roridin E

Hagadorn, Susannah Marie (Massachusetts Institute of Technology, 1987)

I. Total Synthesis of (-)-ptilocaulin. II. Stereoselective reactions of allylboronic esters with substituted aldehydes

Walts, Alan Edmund (Massachusetts Institute of Technology, 1985)